KEGG   Mus musculus (house mouse): 231329
Entry
231329            CDS       T01002                                 
Symbol
Polr2b, Pol2rb, Rpb140, Rpb2
Name
(RefSeq) polymerase (RNA) II (DNA directed) polypeptide B
  KO
K03010  DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03020  RNA polymerase
mmu03420  Nucleotide excision repair
mmu05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    231329 (Polr2b)
  09124 Replication and repair
   03420 Nucleotide excision repair
    231329 (Polr2b)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    231329 (Polr2b)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mmu03021]
    231329 (Polr2b)
   03400 DNA repair and recombination proteins [BR:mmu03400]
    231329 (Polr2b)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.6  DNA-directed RNA polymerase
     231329 (Polr2b)
Transcription machinery [BR:mmu03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Core subunits
     231329 (Polr2b)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      231329 (Polr2b)
SSDB
Motif
Pfam: RNA_pol_Rpb2_6 RNA_pol_Rpb2_1 RNA_pol_Rpb2_2 RNA_pol_Rpb2_7 RNA_pol_Rpb2_4 RNA_pol_Rpb2_3 RNA_pol_Rpb2_5
Other DBs
NCBI-GeneID: 231329
NCBI-ProteinID: NP_722493
MGI: 2388280
Ensembl: ENSMUSG00000029250
UniProt: Q8CFI7
Position
5:77458331..77497175
AA seq 1174 aa
MYDADEDMQYDEDDDEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVE
DAPPIDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTY
SAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLD
PGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSML
ARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEM
VKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETK
KAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQ
KFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLS
HLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSP
ILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSE
VSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASG
VVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSP
RNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIV
AIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGM
RHAIYEKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSE
TGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEG
ITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGY
HLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSR
DGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGC
RNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV
NT seq 3525 nt   +upstreamnt  +downstreamnt
atgtatgacgccgacgaggacatgcaatatgatgaagacgacgatgagatcactccggat
ctgtggcaggaagcatgctggatcgtgatcagttcttactttgatgagaaaggcttggtc
agacaacagctggattcctttgatgagtttattcagatgtctgttcaaagaattgtggaa
gatgcaccaccgattgacctacaggccgaagctcagcacgccagtggagaagttgaagag
ccgccaagatatttactgaagtttgaacaaatttacctctccaaacctactcattgggaa
agagatggtgccccttcgccaatgatgccaaatgaagccaggttaagaaatctcacgtat
tctgctccgctttacgttgacataacaaagacagtcattaaagaaggtgaagaacagctg
cagactcagcaccagaaaacgttcatagggaaaattccaattatgctgcgctccacctac
tgcctgttaaatggcttaacagatcgtgacctgtgtgagctgaatgagtgtcctttggat
cccggtggctattttattatcaatggatcagaaaaggttctgatagctcaagagaaaatg
gcaacaaacacagtctatgtgtttgccaaaaaggattccaagtatgcctatacaggagaa
tgtcgctcatgcctggagaattcttcccgacccaccagtactatatgggttagcatgctg
gccagaggaggacagggtgcaaagaagagtgctattggccagcgcatcgtggcaacgtta
ccatacatcaagcaagaagttcctatcatcattgtgttcagagcactaggctttgtgtct
gatagagatattttagaacacatcatttatgacttcgaggatccagagatgatggaaatg
gttaaaccatctctcgatgaagcgtttgtcatccaagagcagaatgttgccttaaacttc
atcggttcaagaggggcaaagcctggtgttactaaggagaaaagaattaaatatgcaaaa
gaagtcttacagaaagaaatgctccctcacgttggtgtcagtgatttctgtgagaccaaa
aaggcctatttcttggggtatatggttcataggttgcttctagcagccctaggcagaaga
gaactagacgacagagatcactatggcaacaagagattggatcttgctgggcctctgctt
gcattcttattcagaggcatgtttaagaatttgctgaaagaagtacgaatctatgcgcag
aagtttattgatcgcgggaaggattttaacttagagctggcaatcaagacaaggatcata
tctgatgggctaaaatactctttagccactgggaactggggtgaccagaagaaagctcat
caagccagagctggagtatcccaggtattgaaccgcctgacgtttgcatctactctttct
cacctgcgtcgtctaaactctcctattggcagagatggcaagctagcgaagcccagacag
ttgcataataccttgtggggaatggtgtgtcctgctgaaactccagagggccatgctgta
gggcttgtgaagaatttagccctgatggcttatatttcagttggatctcaaccctctcca
attttggaatttttagaagaatggagcatggaaaatttagaagaaatttctcctgcagct
attgctgatgcaaccaagatttttgttaatggctgctgggttggaatccataaagacccc
gaacaactcatgaacacgctaaggaagttacggcggcagatggacatcattgtatccgaa
gtttctatgatcagagatattcgagagcgggagattcggatctatacagatgcaggccgt
atttgtagaccccttctgattgtggaaaagcagaagctgcttttgaagaagagacacatt
gaccagttgaaagagagagaatataacaactacagttggcaggatctggtagccagtggg
gtagtagagtatattgataccctggaagaggagaccgtgatgcttgcaatgactccagat
gatttgcaggagaaggaagtagcttattgttctacctacacccactgtgagattcaccca
tcaatgattcttggagtctgtgcatctattattccttttcctgatcataaccagtcccct
agaaacacataccagtctgctatgggcaagcaggctatgggagtttatatcaccaacttc
catgtgcggatggacaccttggcccatgttctctactatcctcagaaaccccttgtgact
acacggtctatggaatatctacgattcagagagctgccagcaggaatcaactcaattgtg
gccattgcatcctacacgggctataatcaagaagactctgttatcatgaatcgttcagct
gtggatcgaggctttttcaggtctgttttctaccgatcatacaaagaacaagagtctaaa
aagggatttgatcaagaagaagtgtttgagaagcctacacgtgagacatgccagggaatg
aggcatgccatctatgaaaagttggacgatgacggtttgatagctccgggggtccgagtc
tccggagatgacgttattatcggcaagacagtcaccttacccgagaacgaggatgagctg
gagagcaccaacaggcgctacaccaagagggactgcagcactttcctcagaactagtgag
acgggcatcgtggaccaggtcatggtcactctcaaccaggaaggatataaattttgtaaa
ataagggtgcgctctgttagaattccgcagattggagacaaatttgctagccgacatggt
cagaagggaacttgtggtattcagtatagacaagaggacatgccgttcacttgcgaaggc
ataactcctgacatcatcataaacccccacgccatcccctcccggatgacaattggtcac
ttgatcgaatgtctccaagggaaggtctctgccaacaagggtgaaattggtgacgctact
ccatttaatgatgctgtcaatgtgcagaagatttctaatcttttgtctgactatggctac
catctcagagggaacgaggtgctctacaatggattcactggacgaaaaatcacatcacag
atttttattggccccacttactaccagcgtttgaagcatatggtggatgacaaaattcat
tctcgtgctaggggacccattcagattcttaacagacagcccatggagggcagatctcgt
gatggtggcctgcgcttcggagaaatggaacgagactgtcaaattgcccacggtgcagca
cagtttctaagagaaagactgtttgaagcatcagatccgtatcaggttcatgtctgtaat
ctttgtggaataatggcaattgctaacacgaggactcatacatatgagtgcaggggatgc
cgcaataaaacccagatttccttggtgcgaatgccgtacgcgtgcaagctgttgttccag
gagctcatgtccatgagcatcgcaccacgaatgatgagtgtttag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (56)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (49)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (7)   
   Pfam (7)   
All databases (92)   

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