KEGG   Mus musculus (house mouse): 232345
Entry
232345            CDS       T01002                                 
Symbol
A2m, A2mp
Name
(RefSeq) alpha-2-macroglobulin
  KO
K03910  alpha-2-macroglobulin
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04610  Complement and coagulation cascades
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    232345 (A2m)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    232345 (A2m)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    232345 (A2m)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    232345 (A2m)
Peptidases and inhibitors [BR:mmu01002]
 Peptidase inhibitors
  Family I39: alpha2M family
   232345 (A2m)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    232345 (A2m)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   232345 (A2m)
SSDB
Motif
Pfam: TED_complement A2M MG4 MG3 A2M_BRD A2M_recep MG2 SVA MG1 CarboxypepD_reg
Other DBs
NCBI-GeneID: 232345
NCBI-ProteinID: NP_783327
MGI: 2449119
Ensembl: ENSMUSG00000030111
UniProt: Q6GQT1
Position
6:121612920..121656197
AA seq 1474 aa
MGKRWLPSLALLPLPPPLLLLLLLLLPTNASAPQKPIYMVMVPSLLHAGTPEKGCLLFNH
LNETVTVKVSMESVRGNQSLFTDLVVDKDLFHCASFIVPQSSSNEVMFLTVQVKGPTHEF
RRRSTVLIKTKESLVFAQTDKPIYKPGQMVRFRVVSLDENFHPLNELIPLLYIQDSKKNR
IAQWQNFRLEGGLKQLSFPLSSEPTQGSYKVVIRTESGRTVEHPFSVKEFVLPKFEVKVA
VPETITILEEEMNVSVCGIYTYGKPVPGHVTVNICRKYSNPSSCFGEESLAFCEKFSQQL
DGRGCFSQLVKTKSFQLKRQEYEMQLDVNAKIQEEGTGVEETGKGLTKITRTITKLSFVN
VDTHFRQGIPFVGQVLLVDGRGTPIPYEMIFIGADEANQNINTTTDKNGLARFSINTDDI
MGTSLTVRAKYKDSNVCYGFRWLTEENVEAWHTANAVFSPSRSFVHLESLPYKLRCEQTL
AVQAHYILNDEAVLERKELVFYYLMMAKGGIVRAGTHVLPVTQGHKKGHFSILISMETDL
APVARLVLYTILPNGEVVGDTVKYEIEKCLANKVDLVFHPNIGLPATRAFLSVMASPQSL
CGLRAVDQSVLLTKPEAELSASLVYDLLPVKDLTGFPKGVNQQEEDTNGCLKQNDTYING
ILYSPVQNTNEEDMYGFLKDMGLKVFTNLNIRKPKVCERLGVNKIPAAYHLVSQGHMDAF
LESSESPTETTRSYFPETWIWDLVIVDSTGVAEMEVTVPDTITEWKAGAFCLSNDTGLGL
SPVIDFQAFQPFFVDLTMPYSVIRGEAFTLKATVLNYLQTCIRVGVQLEASPDFLATPEE
KEQKSHCICMNERHTMSWAVIPKSLGNVNFTVSAEALDSKELCRNEVPVVPERGKKDTII
KSLLVEPEGLENEVTFNSLLCPTGAEVSEQISLKLPSDVVEESARASVTVLGDILGSAMQ
NTQDLLKMPYGCGEQNMVLFAPNIYVLDYLNETEQLTQEIKTKAITYLNTGYQRQLNYKH
RDGSYSTFGDKPGRSHANTWLTAFVLKSFAQARRYIFIDESHITQALTWLSQQQKDNGCF
RSSGSLLNNAMKGGVEDEVTLSAYITIALLEMSLPVTHPVVRNALFCLDTAWKSARRGAS
GNHVYTKALLAYAFALAGNQDTKKEILKSLDEEAVKEDNSVHWTRAQKPRVPADLWYQPQ
APSAEVEMTAYVLLAYLTTELVPTREDLTAAMLIVKWLTKQQNSHGGFSSTQDTVVALHA
LSKYGAATFTRAKKAAHVTIQSSGAFYTKFQVNNDNQLLLQRVTLPTVPGDYTAKVAGEG
CVYLQTSLKYSVLPREKEFPFALVVQTLPGTCEDLKAHTTFQISLNISYIGSRSDSNMAI
ADVKMVSGFIPLKPTVKMLERSVHVSRTEVSNNHVLIYLDKVSNQMLTLFFMVQQDIPVR
DLKPAIVKVYDYYEKDEFAVAKYSAPCSAGYGNA
NT seq 4425 nt   +upstreamnt  +downstreamnt
atggggaagcgctggctcccaagcctggccctgctgccgctgccgccaccgctgctgctg
ctgctgttgctgctgctgcccacaaatgcctcagcaccacagaaaccaatctacatggtg
atggttccctccctgctccacgctggcacccctgagaagggctgcctcctgttcaaccac
ctaaacgagacagtaacagtgaaagtatccatggagtctgtccgtgggaaccaaagcctc
ttcactgaccttgttgttgacaaggacttattccactgtgcctccttcatcgtcccacag
tcttcatccaatgaggtgatgtttctcactgtccaagtaaaaggaccaactcatgagttc
aggaggaggagcacggtgctgatcaagactaaagagagcctggtctttgctcagactgac
aagcccatctacaaaccaggacagatggtgagatttcgtgttgtctcattggacgaaaat
ttccacccccttaatgaattgattcctctactgtacattcaggattcaaaaaaaaatcgc
attgcacagtggcagaatttccgcttagagggtggcctcaaacagctgtccttccccctc
tcctcagagcccactcagggctcctacaaggtggtgatacgtacagaatcaggcaggacc
gtcgagcaccccttctctgtgaaggaatttgtgcttcccaagtttgaagtcaaagttgca
gtaccagagacaatcaccatcctggaggaagagatgaatgtgtccgtgtgtggcatatac
acctatgggaagcctgttccaggacacgtgactgtgaacatttgcagaaagtacagtaat
ccttctagctgctttggtgaagaatcgctggctttctgtgagaaattcagtcaacagcta
gatggccgtggctgcttctcacagctagtgaaaaccaagtctttccagctaaagaggcaa
gagtatgagatgcagcttgatgtgaatgccaagatccaagaagaaggaacaggtgtggaa
gaaaccggtaaagggctcactaagatcacaagaactataacaaaactatcatttgtgaac
gtggatacacatttcagacaaggaattcctttcgttgggcaggtgctcctggtggatggg
agaggcacccctattccatatgaaatgatcttcattggagctgatgaagcaaaccagaac
ataaatactaccactgataagaatggcctggcacggttctccatcaacactgatgacatc
atgggcacgtccctaactgtcagggccaaatacaaagatagcaatgtctgctatggattt
agatggttgacagaagagaacgtagaggcttggcacactgccaacgctgtcttctcaccg
agcagaagcttcgtgcacctggaatccctgccctataaactgcgctgtgagcaaaccctg
gcggtccaggctcattatattctaaatgacgaggctgtgctggagcggaaggagttggtc
ttctattatctgatgatggcaaagggaggcattgttcgggcagggactcacgttctgcct
gtgacgcagggacacaagaaaggccatttctccatcctcatctcgatggagacagacctg
gctcctgtagctcgactggtcctttataccattctgcccaatggagaagtggttggagat
actgttaaatatgagattgaaaagtgcctggccaacaaggtggatttggtcttccaccca
aatatcggtcttccggccacacgtgccttcctcagtgtcatggcttctcctcagtctctc
tgtggcctgcgagctgtggaccaaagcgtactgctcacaaagcctgaggccgaactctct
gcatccctggtttatgatctgctaccagtgaaagacctcactggcttccctaagggtgtg
aatcaacaggaagaagacactaatggctgccttaagcaaaatgacacttacattaatgga
atcctgtactccccagtacagaatacaaatgaagaggacatgtatggcttcctaaaggat
atgggcttaaaggtattcaccaacttgaacatccgtaaacccaaagtctgtgaacgcctt
ggagtcaataaaataccagctgcataccaccttgtaagccaaggccacatggatgctttt
ctagagtcttcagagtctcccacagagactacacgaagctacttccctgagacgtggatc
tgggacttggtgatcgtggactcaacaggagtggctgaaatggaagtgacagtccctgac
accatcactgaatggaaggctggggccttctgcctgtccaatgacactgggttgggcctc
tctcctgtgatcgatttccaagccttccagcccttcttcgtggatctcacaatgccctac
tccgtgatccgtggagaggccttcacgctcaaggccactgtgctgaactacctccagaca
tgcatccgggttggtgtacagctggaggcctctcctgatttcctagctaccccagaggag
aaggaacaaaagtctcactgcatctgtatgaacgagcggcataccatgtcctgggcggtg
atccccaagtcattaggaaatgtgaatttcacagtgagtgcagaggcactggactctaag
gagctgtgtaggaatgaggtgccagtggttcctgaacgtggaaagaaagacacgatcatc
aagtccctgctggttgaacctgaaggtctagagaatgaagtgacattcaacagtttgctt
tgtccaacaggtgctgaggtatcggaacagatatctctgaaactgccatcagatgtggta
gaggaatctgcccgagcttctgtcacagttttgggagatatattgggttctgctatgcag
aacacacaggatctccttaagatgccctatggctgtggagaacagaacatggttctgttt
gctcctaatatctatgtcctggactatctgaatgaaacagagcagctgacacaggagatc
aagaccaaggccattacctatctcaatacgggttaccaaagacaattaaactacaagcac
cgggatggctcctacagtacttttggggataaacctggtaggagtcatgccaatacctgg
ctcacagcctttgtactgaagagttttgctcaggctcgaagatatatcttcatcgatgaa
tcacacatcacccaagccctcacctggctctcccagcagcagaaggacaatggctgcttc
aggagctccgggtcactgctcaacaatgccatgaagggaggagtagaagatgaagtcact
ttgtctgcctacatcaccattgctctcctggagatgtctcttcctgtcactcatcctgtt
gtccgaaatgccctcttttgcctggacacagcctggaagtcagcgaggagaggagccagc
ggcaaccatgtctacactaaggcactgttggcctatgcatttgcccttgctggtaaccag
gacacgaagaaggagatactgaaatcactcgatgaggaggcggtaaaagaagacaattct
gtccactggaccagagctcagaaacccagagtgccagcagatctctggtaccaaccccag
gctccctcggctgaggtagagatgaccgcttatgtgctcctggcttatcttaccactgag
ctggttccaacccgagaggacctgactgctgcaatgctcattgtgaagtggctcacaaag
cagcagaattcccacggtggcttctcctccacccaggacacggtagtggctctccatgct
ttgtccaaatacggagcagctactttcacaagagcgaagaaagctgcacatgtgaccatc
cagtcttctggcgcattttatacaaaattccaagtgaacaacgacaaccagttattatta
cagagagtcacattgccaactgtgcctggggattacaccgcaaaggtagctggagaaggg
tgtgtctacctccagacatccttgaaatatagtgttctcccgagggagaaggagtttcca
tttgctttggtggtgcagactctgcctgggacttgtgaggatctcaaagctcacaccacc
ttccagatctcactcaatatcagttacattggaagccgttctgactccaacatggcaatt
gctgatgtgaagatggtgtctggcttcatccccttgaaaccaacagtgaaaatgcttgaa
agatctgtgcatgtgagccggacggaagtcagcaataaccatgtcttgatttacttggat
aaggtgtcaaatcagatgctgaccttgttcttcatggtgcagcaagatattccagtgaga
gacctgaagccagccatagtgaaagtctatgattactacgagaaagatgagtttgcagtt
gcaaaatacagtgctccctgcagtgcaggttatggaaatgcctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
Protein domain (10)   
   Pfam (10)   
All databases (61)   

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