KEGG   Mus musculus (house mouse): 233328
Entry
233328            CDS       T01002                                 
Symbol
Lrrk1, C230002E15Rik, D130026O16Rik, mKIAA1790
Name
(RefSeq) leucine-rich repeat kinase 1
  KO
K08843  leucine-rich repeat kinase 1 [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    233328 (Lrrk1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     233328 (Lrrk1)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: TKL group
  LRRK family
   233328 (Lrrk1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr LRR_8 COR LRR_4 Ank_2 Roc Ank Ank_3 Ank_5 Ank_4 Arf Ras Gtr1_RagA MMR_HSR1
Other DBs
NCBI-GeneID: 233328
NCBI-ProteinID: NP_666303
MGI: 2142227
Ensembl: ENSMUSG00000015133
UniProt: Q3UHC2
Position
7:complement(65908493..66038089)
AA seq 2014 aa
MAGTSQRPPSMYWCVGTEGLAVCPGPAMETHNGAEDMGSKLSLPGGSSTVQCPSMEEIHT
AYKQRNLSRARDLLRGVCEESESSQEKGQLLSIAAAHGDLETVQFLLTEKRVELPTEPTD
DNPAVVAAHFGHAEVVRELLESLPGPCTPQRLLNWMLALACQRGHLEVVKLLVLTHGADP
ENYAVRKNEFPVIVRLPLYAAIKAGNEDIAIFLLRHGAYFCSYILLDSPEPSKHLLRKYF
IEASALPSSYPGKIALRVKWSHLKLPWVDLDWLLDISCQITELDLSANCLPSLPSIIPWG
LINLKKLNLSNNQLGELPCVQSSDEIICSRLLEIDISSNKLSHLPPGFLHLSKLQKLTAS
KNYLERLFEEENATNWIGLRKLQELDLADNRLTELPVQFMHSFKSLTSLNVSRNNLKSFP
DPWSCPLKCCKASKNALESLPDKMAVFWKSHLRDADFSENSLKEVPLGLFQLDALMFLRL
QGNQLLSLPPQEKWTCTQLKTLDLSRNQLGKNEDGLKTKRISLFTTRGRQRSGTETASML
EFPAFLSESLEVLCLNDNHLDAVPPSVCLLKNLSELYLGNNPGLRELPPELGQLGNLWQL
DIEDLNISNVPAEVRKEGPKATLSFLRAQLRKAEKCKLMKMILVGPPRQGKSTLLEILQT
GKAPQLAHSEATIRTTKWELQRPAGSKAKVESVEFNVWDIGGPASMATVNQCFFTDKALY
VVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLA
LCRSPSGSRATGFPDITFKHLHEISCKNLEGQEGLRQLIFHVTCNMKDVGSTIGCQKLAG
RLIPRSYISLQEAVLAEQQRRSLGDQVQYLTDRQLDQLVEQTPGNDIKDYEDLQSAISFL
IETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIQAEDLRMLLVG
TGFTQQTEEQYFQFLAKFEIALPVANDSYLLPHLLPSKPGLDTHSMRHPMANTIQRVFKM
SFVPVGFWQRFIARMLISLAEMDLQLFENKKNTKSRNRKVTIYSFTGSQRNRCSTFRVRR
NQTIYWQEGLLVTFDGGYLSVESSDVNWKKKKSGGIKIICQSEMRDFSAMAFITDHVNSL
IDQWFPALTATESDGTPLMEQYVPCPVCEASWAQHADPNERSESVQYFDMEDCVLTAIER
DFISCPRHPDLPVPLQELVPELFMTDFPARLFLENSKLEHTEGENSILGQGGSGTVIYQA
RYQGQPVAVKRFHIKKFKNSANAPADTMLRHLRAMDAMKNFSDFRQEASMLHALQHPCIV
SLIGISIHPLCFALELAPLGSLNTVLSENAKDSSFMPLGHMLTQKIAYQIASGLAYLHKK
NIIFCDLKSDNILVWSLSAKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPRIV
YDEKVDMFSYGMVLYELLSGQRPALGHHQLQIVKKLSKGIRPVLGQPEEVQFHRLQALMM
ECWDTKPEKRPLALSVVSQMKDPTFATFMYMLPCGKQSAFFSSQSQEYTVVFWDGKEESR
NYTVVNTEKGLLEVQRMTCPGMKLSCQLKVQSSVWIATEDQKIYIYSLKGMCPLSVPQQA
LDTPAVVTCFLAVPVIKKNSFLVLAGLADGLVAVFPVARGTPKESCSYLCSHTANRSKFC
IPDEDARQNPYPVKAMEVVNSGSEVWYSNGPGLLVIDCTILDISRRLEPYAAPSMVTSLV
CSSDCRGEEMVWCLDDKANCLVMYHSATYQLCARYFCGDPNPLRDTFSVQPSVLETPGSH
KTTSKGPVEECIADVSIMYSEELGTQILTHQDSLTDYCSMSSYSSSPPHQDPRSPSSLPS
SLTSYSSVPFSANYEDSDRLQEPSVTSDRTEHDLSPMDGETFSQHLQAVKVLAVKDLIWV
PRHGGDIIVIGLEKDSGAQRGRVIAVLKARELNRHGVLVDAAVVAKDTVVCSFANENTEW
CLAVWRGWGAREFDIFYQSYEELGRLEACTRKRR
NT seq 6045 nt   +upstreamnt  +downstreamnt
atggctggcacgtcacagcggccacccagtatgtactggtgtgtggggacagaaggatta
gctgtgtgtccaggacctgccatggagacccataatggtgccgaagacatgggcagcaaa
ctgtctttaccaggtggcagctccacggtgcagtgccccagcatggaagaaatccacact
gcgtacaagcagaggaacctctcccgagcccgagacctactcagaggggtttgtgaagag
agcgaatcctcacaggagaagggccagctgctgagcatcgcggcagcccacggggatctg
gagactgttcagttcctgctcactgagaagcgcgtggagctgccgacggagcccaccgat
gacaacccagctgtggtggcagcgcattttggacacgccgaagtagtacgtgaactacta
gagtccttgccaggtccctgtaccccccagcggctactgaactggatgctggccctggct
tgccagcgagggcacctggaggttgtgaagctgctggtcctgacacatggggctgacccg
gagaactatgccgtcaggaagaatgagttccccgtcattgtgcggttgcccctctatgcg
gccatcaaggcagggaatgaagacattgccatattcctgcttcggcacggagcctatttc
tgctcctacatcctgctggatagtcctgagccaagcaaacatctgctcaggaagtatttc
atcgaagccagcgccctgcccagcagctatcccgggaaaatcgcacttcgtgtgaaatgg
tcccatctgaagttgccctgggtggacctggactggctcctagacatctcctgccagatc
acagagcttgacctgtctgccaactgcctgccttcgctcccttccatcatcccttgggga
ctcatcaatctaaagaagctgaatctctcaaacaaccagctgggggagctgccctgcgtg
cagtcctccgacgaaatcatctgctccaggttacttgaaattgacatctccagcaacaaa
ctgtctcacctccctcctggattcctgcacctctcaaaacttcaaaagctgactgcttcc
aaaaactacctggagcggctgtttgaagaagaaaacgccactaactggatcggcctgcgg
aagctgcaagaactcgatctagctgacaacaggctgacagagctccctgtccaatttatg
cactccttcaagtctctcacctctctgaatgtctccaggaacaacctgaagagcttcccg
gatccctggtcctgccctttgaaatgttgtaaagcctccaaaaatgccctggaatcgctg
ccagacaaaatggctgtcttttggaaaagccaccttcgggatgcagatttctctgagaac
tctctgaaagaggtgcccctgggattgttccagcttgacgccctcatgttcttgaggtta
cagggaaaccagctgttgtcgctgccacctcaagagaagtggacctgcacccaactcaag
accctggacctctccagaaaccagctcggcaaaaatgaagatgggcttaaaacaaagagg
atctccctgttcaccaccagagggcgccagcgttctggaactgagacagcctccatgttg
gaattcccagctttcctaagtgagtctttggaggtcctttgtctgaatgacaaccatctt
gatgctgttcccccatcggtctgcctgctgaagaacctctcagagctctacttgggcaat
aaccctggcctccgagagctccctccggagctaggccagctggggaacctctggcaactg
gacattgaagatctgaacattagcaacgtgcctgcggaggtcaggaaagaaggcccgaaa
gcaacactgtctttcctgcgtgctcagctgcgcaaagcagagaagtgtaagctgatgaag
atgatcctcgtgggtcccccgcgccagggcaagtccacactcctggagatcttacagacc
gggaaggccccgcagctagcacacagtgaagccaccatcaggaccaccaagtgggagctc
cagagaccagcaggctccaaagccaaggttgagtccgtagagttcaacgtctgggacatc
gggggtccggccagcatggccacggtcaatcagtgcttcttcacagacaaggcgctgtat
gtggtggtctggaacctggcactgggagaggaagccgtggccaacctccagttctggctg
ctcaacattgaggccaaggccccaaatgccgttgtgctggtggtcgggacacacctggac
ctaatcgaagctaagttccgagtggagaggatagcaaccctgcgtgcctacgtgctggcc
ctctgccgctcgccatcgggctccagggctacgggcttcccggacatcactttcaaacac
ttgcatgagatctcctgcaagaatctggaagggcaggaggggctgcggcaactgatcttc
cacgtcacgtgcaacatgaaggatgtgggtagcactatcggctgtcaaaaactcgccggc
aggctgatccccaggagctacataagcctacaggaggccgtgctggctgagcaacagcgc
cgcagtctgggtgaccaagtacagtatctgacggacaggcagctggaccagctggtagag
cagacgcctggcaatgatatcaaagactatgaagacctgcagtctgccatcagcttcctc
atagaaactgggaccctgctgcactttccagacacgagccatggcctaaggaacctctac
ttcctggatcccatctggctctctgaatgcctgcagaggatctttaacatcaagggctcg
cggtcagtggcaaagaatggggtgatccaagcggaagacctcaggatgctgctggtgggg
acaggcttcacacagcagactgaggagcaatacttccagttccttgccaagttcgagatt
gccctccctgttgccaatgacagctacctcctaccacacctccttccatccaagcctggg
ctggacacccacagcatgcggcacccaatggctaacaccatccagcgggtgtttaagatg
agcttcgtgcctgttggcttctggcaacggttcatagcacggatgctaatcagcttggct
gagatggacctgcagctttttgaaaacaagaagaatacgaaaagcaggaaccggaaagtc
actatttacagttttacagggagccagagaaaccgctgcagtacattccgagtccgaaga
aatcagaccatctactggcaggaagggctgctggtcactttcgatgggggctacctcagt
gtggaatcctcagatgtgaactggaaaaagaaaaaaagcggaggaattaaaatcatctgc
cagtcagagatgagggacttctcggcaatggcttttatcacagaccatgtcaactccctg
attgaccagtggttccctgccctgacggccacagaaagtgacgggaccccactgatggag
cagtacgtaccctgccctgtctgtgaagcatcctgggcccagcatgcagatccaaacgag
aggtcagagagcgtgcagtactttgatatggaagactgtgtgctcacagccatcgaacgg
gacttcatctcctgccccagacacccagacctcccagtaccacttcaggagcttgtacca
gagctgttcatgactgacttcccagccaggctcttcctggagaacagcaagctggagcac
acggagggtgagaacagcattctgggccaaggtggcagtggcacagtcatctaccaggcc
cggtaccagggccagcctgtggctgtgaagaggttccatatcaagaagttcaagaattct
gctaatgccccagcagacaccatgctgcggcacctgagagccatggatgccatgaagaac
ttctcagatttccgtcaggaggccagcatgctgcatgccttgcagcatccttgcatcgtg
tcactcatcggcatcagcatccacccgctctgcttcgccttggagctggccccgctgggc
agtctcaacaccgtgctatctgagaatgccaaagattcttcctttatgcccctgggacac
atgctcacccaaaagatagcctaccagattgcctcgggcctggcctacctgcacaagaaa
aacatcatcttctgtgacctcaagtcggacaacatcctagtgtggtcgctgagcgccaag
gagcatatcaacatcaaactgtcagactacggcatctccaggcagtcctttcacgagggg
gccctgggtgtggagggcaccccaggttaccaggccccagagatcaggcctcgcatcgtg
tatgacgagaaggtagatatgttctcctacggcatggtgctatacgagctgctgtcagga
cagcgtcctgcactgggccaccaccaacttcagattgtcaagaagttgtccaagggcatc
cgcccagttctggggcagccggaggaagttcagttccatcggctgcaggcgctcatgatg
gagtgctgggacacaaagccggagaagcgccccctggccttgtccgtggtgagccagatg
aaagacccaacctttgccaccttcatgtacatgctgccctgtgggaagcagtcggccttc
ttctcatcccagagccaggagtacactgtggtgttctgggatgggaaggaggagtccagg
aattacacggtggtcaacacagagaagggccttctggaagtacagaggatgacctgcccc
gggatgaagttgagctgtcagctcaaggtccagagctcagtgtggatagccacggaggac
cagaaaatctatatctacagccttaagggtatgtgcccattaagcgtgccccagcaggcc
ctggacaccccagctgtcgtcacctgtttcttggcagtacctgttatcaaaaagaactcc
ttcctggtgctggcaggcctggctgacggactcgtggctgtgtttcctgtggcacggggc
accccaaaagaaagctgctcctacctgtgctcccacacagccaacaggtccaagttctgc
atccccgacgaagatgcacggcagaacccttacccagtgaaggcaatggaagtggtcaac
agtgggtctgaggtctggtacagcaacgggcctggcctcctcgtcattgactgcaccatc
ctggacatcagcaggcggctggagccctacgcagctccgtccatggtcacgtcacttgtg
tgcagctcagactgcagaggagaggagatggtctggtgcctcgacgacaaggccaattgc
ttagtgatgtaccactcagccacctaccagctctgtgcccggtacttctgtggggacccc
aatcctctcagggacacgttttctgtgcagccttcagtcctagaaaccccaggcagtcac
aaaaccacctcaaaggggcctgtggaagagtgcatcgcggatgtgagcatcatgtacagc
gaggagctgggcacgcagatcctcacccaccaggactcgctcaccgactactgctccatg
tcctcttattcttcgtccccaccccaccaagatcctaggtccccttccagtctgcccagc
tccctcaccagctattccagtgtgcctttctctgccaactatgaagactcagacaggctg
caggagcccagtgtcacctctgacagaactgagcatgacctgagccccatggatggggag
acgttcagccagcacctgcaggctgtgaaggtgcttgctgtcaaagacctcatttgggtt
cctagacatggaggagatatcattgtcatcggcctggagaaggattcaggtgcccagcgg
ggcagagtcatcgctgttttaaaagcccgagagctcaatcggcacggggttctggtggat
gccgcagtggtggcaaaggacaccgtagtgtgcagctttgcaaatgaaaacacagagtgg
tgcctggctgtctggaggggctggggcgccagggagtttgacatcttctaccagtcctat
gaggagctgggccggctggaggcttgtactcgcaagagaaggtaa

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Ontology (3)   
   KEGG BRITE (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (38)   
   RefSeq(nuc) (6)   
   GenBank (16)   
   EMBL (16)   
Protein domain (15)   
   Pfam (15)   
All databases (90)   

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