KEGG   Mus musculus (house mouse): 234878
Entry
234878            CDS       T01002                                 
Symbol
Map3k21, Mlk4, mKIAA1804
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 21
  KO
K17534  mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    234878 (Map3k21)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    234878 (Map3k21)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     234878 (Map3k21)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: TKL group
  MLK family
   234878 (Map3k21)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH3_9 SH3_1 SH3_2 ABC1 Pkinase_fungal RNase_Y_N OmpH
Other DBs
NCBI-GeneID: 234878
NCBI-ProteinID: NP_663583
MGI: 2385307
Ensembl: ENSMUSG00000031853
UniProt: Q8VDG6
Position
8:126637189..126674179
AA seq 1002 aa
MALPVAEGTADTPLSPARDDSGSTSSGMWAALYDYEARGEDELSLRRGQLVEVLSQDAAV
SGDEGWWAGQVQRRLGIFPASYVAPCGPVPPPAPPPPRPCSPVHVDFERLELKELIGAGG
FGQVYRATWQGQEVAVKAARRDPEQDAAAAAESVRREARLFAMLRHPNIIQLRGVCLRQP
HLCLVLEFARGGALNRALAAAASDPRAPGPRRARRIPPQVLVNWAVQIARGMLYLHEEAV
VPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRTTRMSAAGTYAWMAPEVI
RSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKL
MKECWEQDPHIRPSFALILQQLTAIEEAVLTNMPQESFHSMQEDWKLEIQQMFSELRTKE
KELRSREEELSRAALQQKSQELLLRRREQQLAEREIDVLERELNVLIFQLSQEAPHVKKR
KGRFRRGRLRLKDGHRISLPSDFQHKITVQASPTLDKRRSSDSGLCSPPGSPLMLPRLRA
IQLTSDENNKTRGRNMVFRQEDFEDVKRSFKKKGCTWGPSSVQTKERPEGRERVRPLSDG
NSPWSSLLIKSQKTTPLASLFVDQPGSCEEQKLVPEGLEHRKPKQTKFPGQAHVGLPLCK
DSQREDSSEAESREEGSPKGSPVNNVGAPMLRKKTESALCECGMLLASMALGLDVRKLHG
AQAPAKPSPKMEKKEEGALQPASRCQSSPSSLLRQPSAGRAPSGGSTLLLPSAPSHSSKS
SLSMKCLLQAGKEESSLGNARDLCGPTTLTPDPGSAAPESGCELIPGLRPKTDYGVLRSM
PHAILEQTGERLPGCAIVGDKGCHHMQMGSEETPLWLQSAPEDSGLPHSPSPGPQRDLAS
QASLVKPEGVLGECQACPALPQRPHTASVRTTSPPTWVCDKDHQVPALACLLGAQERSRC
QTPSLLDASIEGQKKDCAMPLCRVKSVMCQPSIYALEKDFLT
NT seq 3009 nt   +upstreamnt  +downstreamnt
atggctctacctgtagccgagggcacggctgacacgccgctgtccccggcccgggacgac
tcggggagtacctcctccgggatgtgggccgcgctttatgattacgaagcgcgcggtgag
gacgagctgagcctgaggcgcggtcagctggtcgaggtactgtcgcaggacgccgcggtg
tcaggagacgagggctggtgggccggccaagtgcagcggcgcctgggcatctttccggcc
agctacgtggcgccctgtggcccggtgccgccgccggcgccgcccccgccgagaccctgc
tcgcctgtgcacgtagacttcgagcgcctggagctcaaggagctgatcggcgccggcggc
ttcggtcaggtgtaccgcgccacctggcagggccaggaggtggcggtgaaggcggcgcgc
cgggacccggagcaggacgcggcggcggcggccgagagcgtacggcgcgaggcgcggctc
ttcgctatgctgcggcaccccaacatcatccagctgcggggtgtgtgcctgcggcagccg
cacctctgcctggtgctggagttcgcgcgtggcggcgcgctcaaccgcgcgctggcggcg
gcagcatcggatccgcgagcgcccggcccccgccgcgcgcgccgcatccccccacaggtt
ctggtcaactgggcggtgcagatcgcccgcggcatgctgtacctgcacgaggaggcggtg
gtgcccatcctgcaccgtgacctcaagtccagcaacattttgctgctggagaagatagaa
catgatgacatttgcaacaagaccctgaagatcacggactttgggctagcgagggaatgg
cacaggaccaccaggatgagcgcagcagggacctacgcctggatggctcccgaggtcatc
aggtcctccctgttctccaagggcagcgacatctggagctatggagtgctgttgtgggag
ctgctcactggtgaggtcccgtaccgtggcatcgatggactggctgtggcgtacggggtg
gctgtcaacaagctcacactgcctattccatccacctgccctgaaccgtttgcaaaactc
atgaaagagtgctgggaacaagaccctcatatccgcccctcgtttgccttaattcttcag
cagctgactgcgatcgaagaggcagtgttgaccaacatgccccaggagtccttccattcc
atgcaggaagactggaaactggagattcagcaaatgttcagtgagctgcgaaccaaggag
aaggagctgcgttcccgagaggaggagctgagccgagctgccttgcaacagaaatcgcag
gaactgctgctcagacgccgcgagcagcagctcgcggagcgtgagatcgacgtgctggag
cgcgagctgaacgtgctcatcttccagctgagccaggaggctccccacgtgaagaagagg
aagggaaggttcaggagaggacggctgaggctcaaagacggccaccgcatcagcctgcct
tcagatttccagcacaagatcacagtgcaggcttccccgacgctggacaagcgccgaagc
tcagacagcggactgtgcagcccacccggcagccccttgatgctcccccgcctccgggct
attcagttaacttcagatgagaacaataaaacccggggaaggaacatggtcttccgccaa
gaagactttgaagacgtgaaaaggagtttcaagaaaaaaggatgtacgtggggaccaagc
tccgttcaaacaaaggaaagaccagaaggcagagagagggtcagacctctctcagatggc
aacagcccttggtcatctcttttaataaaaagccagaaaaccacacccttggcttcactg
tttgtggaccagccaggttcttgtgaggagcagaaacttgtccctgaaggattagaacat
agaaaaccaaagcaaacgaagttccctggccaggcccacgttggtctacctctttgcaaa
gacagccagagagaagactcatcagaggctgagagtcgggaggagggatcccctaagggg
tccccggtgaacaacgtgggtgcacccatgctgaggaagaaaacggagtcagcgctgtgt
gagtgtgggatgctgctggcatcgatggctttgggactggatgtcaggaaacttcacgga
gcccaggcccccgcaaaaccatcacccaagatggaaaagaaggaagagggtgccctccaa
cctgcctccaggtgccaatcaagtcccagttcccttctgaggcagccatctgcaggcagg
gcacccagcggtggctccacgctcctgctgcccagtgccccaagccattcctcaaagtct
tctctctccatgaagtgtttgctgcaggctggtaaggaggagtcatctttggggaatgct
cgggacttgtgtggtcctacgacgctcactccagatcctggctctgccgcaccagagagc
ggctgtgaactcatccccggactgagacctaagactgactatggtgtgttgagaagcatg
ccgcatgccatcctggagcagacaggggagagactgccaggctgtgccattgtaggagac
aaaggatgccaccacatgcagatgggatctgaagaaactcctctctggctccaaagtgcc
cctgaagactctggattaccacactctccctcccctggacctcaaagggacctggccagc
caggcctctcttgtgaaacctgaaggtgttctgggcgagtgccaggcatgcccggctctg
ccacaaaggccacacactgcttcggtgagaacaacatctccacctacctgggtttgtgac
aaggaccatcaggtgccagcccttgcctgcttgcttggtgctcaggagagaagcaggtgt
cagactccttccttgctggatgccagcatagaaggtcagaagaaggactgtgccatgccc
ttgtgtagagtgaagagcgtgatgtgtcagccgtccatctacgccctggagaaagacttt
ctgacctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (9)   
   Pfam (9)   
All databases (52)   

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