KEGG   Mus musculus (house mouse): 23918
Entry
23918             CDS       T01002                                 
Symbol
Impdh2, IMPD, IMPD_2, IMPDH-II
Name
(RefSeq) inosine monophosphate dehydrogenase 2
  KO
K00088  IMP dehydrogenase [EC:1.1.1.205]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu00983  Drug metabolism - other enzymes
mmu01100  Metabolic pathways
mmu01232  Nucleotide metabolism
Module
mmu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    23918 (Impdh2)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    23918 (Impdh2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    23918 (Impdh2)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.205  IMP dehydrogenase
     23918 (Impdh2)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   23918 (Impdh2)
  Exosomal proteins of breast cancer cells
   23918 (Impdh2)
SSDB
Motif
Pfam: IMPDH CBS NMO FMN_dh His_biosynth NanE ThiG Dus Glu_synthase G3P_antiterm YceG_bac B12-binding DUF561 DHO_dh
Other DBs
NCBI-GeneID: 23918
NCBI-ProteinID: NP_035960
MGI: 109367
Ensembl: ENSMUSG00000062867
UniProt: P24547 Q3UAT9
Position
9:108437635..108442776
AA seq 514 aa
MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT
LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV
LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMT
KREDLVVAPAGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDA
KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVI
GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP
VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM
DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR
AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
NT seq 1545 nt   +upstreamnt  +downstreamnt
atggcggactacctgattagcggaggcacctcttacgtgccggacgacgggctcacagcg
cagcagctcttcaactgcggggacggcctcacctacaatgattttctcattcttcctggg
tatatcgacttcactgcagatcaggtggacttgacgtctgctctaactaagaagattaca
ctaaagaccccattggtttcctcacccatggacactgtcacagaggctggaatggccatc
gcgatggcgcttacaggaggtattggtttcatccaccacaactgcacacctgaattccag
gccaatgaagttcggaaagtgaagaaatacgaacagggattcatcactgaccccgtggtc
cttagccccaaggatcgtgtacgcgatgtttttgaggccaaagccaggcatggcttctgt
ggtatccccatcacagatacaggccggatggggagtcgattggtgggcatcatctcctca
agggacattgatttcctcaaggaggaagagcatgaccggttcttggaagagatcatgact
aagagggaagatttggtggtcgcccctgccggcgtcactctgaaagaggcaaatgagatt
ctgcagcgaagtaaaaagggaaagttgcccattgtgaatgaaaatgatgagctggtagcc
atcattgcccggacagacctaaagaagaatcgtgattaccccctggcctccaaagatgcc
aagaagcaactgctgtgtggggcagccattggcactcatgaggatgacaagtataggctg
gacttactggcccttgctggtgtggatgtagtggttttggactcttcccagggaaactcc
atcttccaaatcaatatgatcaaatacatcaaggagaagtatcccagtctacaggtcatt
ggaggcaatgtagtcactgctgcgcaagccaagaacctcatagatgcaggtgtagatgct
ttgcgagtcggcatgggaagtggttccatctgcatcacccaggaagtgttggcctgtggg
cggccccaagccacagcagtgtacaaggtctctgagtatgcccgtcgctttggtgttcct
gttattgctgatggaggaatccaaaatgtgggtcatattgccaaagctttggctcttggg
gcttccacagtcatgatgggctccctcctggctgccaccactgaggcccctggcgagtac
ttcttctcagatgggatccggctgaagaaataccgaggtatgggttctcttgatgccatg
gacaaacatctcagcagccagaaccgatacttcagtgaagctgacaaaatcaaagtggcc
caaggagtttcaggggcagtgcaggacaaggggtctatccacaagttcgttccttacctg
attgctggcatccagcattcctgtcaggacattggtgccaagagtttaacccaagtcaga
gccatgatgtactcgggggagcttaaatttgagaagaggacatcctctgctcaggtggaa
ggtggcgtccacagcctccattcgtacgagaaacggcttttctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (48)   
   RefSeq(nuc) (2)   
   GenBank (23)   
   EMBL (23)   
Protein domain (14)   
   Pfam (14)   
All databases (103)   

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