KEGG   Mus musculus (house mouse): 26362
Entry
26362             CDS       T01002                                 
Symbol
Axl, Ark, Tyro7, Ufo
Name
(RefSeq) AXL receptor tyrosine kinase
  KO
K05115  AXL receptor tyrosine kinase [EC:2.7.10.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu04148  Efferocytosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    26362 (Axl)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    26362 (Axl)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    26362 (Axl)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     26362 (Axl)
Protein kinases [BR:mmu01001]
 Receptor tyrosine kinases (RTK)
  AXL family
   26362 (Axl)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase fn3 Ig_3 Ig_2 ig I-set V-set C1-set Pkinase_fungal Pur_ac_phosph_N DUF2627 DUF4381 ABC1
Other DBs
NCBI-GeneID: 26362
NCBI-ProteinID: NP_033491
MGI: 1347244
Ensembl: ENSMUSG00000002602
UniProt: Q00993 Q8CCF8
Position
7:complement(25455925..25488502)
AA seq 888 aa
MGRVPLAWWLALCCWGCAAHKDTQTEAGSPFVGNPGNITGARGLTGTLRCELQVQGEPPE
VVWLRDGQILELADNTQTQVPLGEDWQDEWKVVSQLRISALQLSDAGEYQCMVHLEGRTF
VSQPGFVGLEGLPYFLEEPEDKAVPANTPFNLSCQAQGPPEPVTLLWLQDAVPLAPVTGH
SSQHSLQTPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQRPHHLHVVSRQPTELEVAWT
PGLSGIYPLTHCNLQAVLSDDGVGIWLGKSDPPEDPLTLQVSVPPHQLRLEKLLPHTPYH
IRISCSSSQGPSPWTHWLPVETTEGVPLGPPENVSAMRNGSQVLVRWQEPRVPLQGTLLG
YRLAYRGQDTPEVLMDIGLTREVTLELRGDRPVANLTVSVTAYTSAGDGPWSLPVPLEPW
RPGQGQPLHHLVSEPPPRAFSWPWWYVLLGALVAAACVLILALFLVHRRKKETRYGEVFE
PTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGE
FGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQ
GSDREGFPEPVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIASGMEYLSTK
RFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVY
TSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPVDCLDGLYALMSRCW
ELNPRDRPSFAELREDLENTLKALPPAQEPDEILYVNMDEGGSHLEPRGAAGGADPPTQP
DPKDSCSCLTAADVHSAGRYVLCPSTAPGPTLSADRGCPAPPGQEDGA
NT seq 2667 nt   +upstreamnt  +downstreamnt
atgggcagggtcccgctggcctggtggttggcgctgtgctgctgggggtgtgcagcccat
aaggacacacagaccgaggctggcagcccgtttgtggggaacccagggaatatcacaggt
gccagaggactcacggggacacttcggtgtgagctccaggttcagggggaaccccctgag
gtggtgtggcttcgagatggacagatcctagaactggctgataacacccagacccaggtg
cctctgggcgaagactggcaagatgaatggaaagttgtcagtcagctcagaatctcagcc
ctgcaactttcagatgcaggggagtaccagtgtatggtgcatctagaaggacggaccttt
gtgtctcagccgggctttgtagggctggaaggtctcccgtacttcctggaggagcctgag
gacaaagctgtgcctgccaacacccctttcaacctaagctgccaggcccagggacccccg
gaacccgtgaccctactctggcttcaagatgctgtccccctggccccagtcacaggacac
agctcccagcacagtctgcaaactccaggcctgaacaagacatcttctttctcatgtgaa
gcccacaatgccaagggagtcaccacctcccgcacagccaccatcacagtgctcccccag
aggcctcaccatctccacgtggtttccagacaacctacggagctagaggtagcttggacc
cctggcctgagtggcatctacccgctcacccactgcaacctgcaggccgtgctgtcagac
gatggggtgggtatctggctgggaaagtcagatcctcctgaagaccccctcaccttgcaa
gtatcagtgcccccccaccagcttcggctggaaaagctccttcctcacaccccgtatcac
atccggatatcctgcagcagcagccagggcccctcaccttggacccactggcttcctgtg
gagaccacagagggagtgcccttgggtccccctgagaacgttagcgccatgcggaatggg
agccaggtcctcgtgcgttggcaggagccaagggtgcccctgcaaggcaccctgttaggg
taccggctggcatatcgaggccaggacacccccgaggtacttatggatatagggctaact
cgagaggtgaccttggaactgcggggggacaggcctgtggctaacctgactgtgtctgtg
acagcctatacctcggctggggatgggccctggagccttcctgtgcccctagagccctgg
cgcccagggcaaggacagccactccaccatctggtgagtgaacccccacctcgcgccttc
tcgtggccttggtggtatgtactgctgggagcacttgtggctgccgcctgcgtcctcatc
ttggccctgttccttgtccatcggaggaagaaggagactcgatatggggaggtgtttgag
ccaaccgtggaaagaggtgaactggtagtcaggtaccgtgtccgaaagtcctacagccgg
cggaccactgaagccaccttgaacagtctgggcatcagtgaagagctgaaggagaaacta
cgagacgtcatggtagatcggcataaggtggccttggggaagaccctgggagaaggagaa
tttggcgctgtgatggaaggtcagctcaatcaggatgactccatcctcaaggtcgctgtg
aagaccatgaaaattgccatctgcacaagatcagagctggaggatttcctgagtgaagct
gtctgcatgaaggaatttgaccaccccaacgtcatgaggctcattggcgtctgttttcag
ggctctgacagagagggtttcccagaacctgtggtcatcttgcctttcatgaaacacgga
gacctacacagtttcctcctgtactcccggctcggggaccagccagtgttcctgcccact
cagatgctagtgaagttcatggccgacattgccagtggtatggagtacctgagtaccaag
agattcatacatcgggacctggctgccaggaactgcatgctgaatgagaacatgtccgtg
tgtgtggcagacttcgggctctccaagaagatctacaacggggattactaccgccaaggg
cgcattgccaagatgccagtcaagtggattgctattgagagtctggcagatcgggtctac
accagcaagagcgatgtgtggtccttcggtgtgacaatgtgggagatcgccacccgaggc
caaactccctatccaggggtggagaacagtgagatttacgactacctgcgtcaaggaaat
cggctgaaacagcctgtggactgtctggacggcctgtatgccctgatgtctcggtgctgg
gaactgaaccctcgagaccggccaagttttgcggagctccgggaagacttggagaacaca
ctgaaggctctgccccctgctcaggagccagatgaaatcctctatgtcaacatggatgag
ggcggaagccaccttgaaccccgtggggctgctggaggagctgaccccccaacccaacct
gatcctaaggattcctgtagctgtctcactgcagctgacgtccactcagctggacgctat
gtcctttgtccttctacagccccaggacccactctgtctgctgacagaggctgcccagca
cctccagggcaggaggacggagcctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (35)   
   RefSeq(nuc) (7)   
   GenBank (14)   
   EMBL (14)   
Protein domain (14)   
   Pfam (14)   
All databases (94)   

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