KEGG   Mus musculus (house mouse): 26403
Entry
26403             CDS       T01002                                 
Symbol
Map3k11, 2610017K16Rik, Mlk3, PTK1, SPRK
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 11
  KO
K04419  mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04932  Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    26403 (Map3k11)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    26403 (Map3k11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    26403 (Map3k11)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     26403 (Map3k11)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: TKL group
  MLK family
   26403 (Map3k11)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH3_9 SH3_1 SH3_2 Pkinase_fungal Abi_alpha
Other DBs
NCBI-GeneID: 26403
NCBI-ProteinID: NP_071295
MGI: 1346880
Ensembl: ENSMUSG00000004054
UniProt: Q80XI6
Position
19:5738764..5752893
AA seq 850 aa
MEPLKNLFLKSPLGSWNGSGSGGGGGTGGVRPEGSPKATAAYANPVWTALFDYEPNGQDE
LALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSRGGGPPPCEVASFQELRL
EEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIAL
KAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIH
RDLKSNNILLLQPIEGDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVIKASTF
SKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCW
AQDPHRRPDFASILQQLEALEAQVLREMPRDSFHSMQEGWKREIQGLFDELRAKEKELLS
REEELTRAAREQRSQAEQLRRREHLLAQWELEVFERELTLLLQQVDRERPHVRRRRGTFK
RSKLRARDGGERISMPLDFKHRITVQASPGLDRRRNVFEVGAGDSPTFPRFRAIQLEPTE
SGQTWGRQSPRRLEDSSNGERRACWAWGPSSPKPGEAQNGRRRSRMDEATWYLDSDDSSP
LGSPSTPPALNGNPPRPSPEPEEPRRAGPTERGNSSGTPKLIQRALLRGTALLASLGLGR
DLQPPGGLSRERGESPTAPPPAQMPSPCPPELPSTPLIRLSQTTPDAHSSPTPGPLLLDL
GVPSGQPSAKSPRREETRGRTVSPPPGISRSAPGTPGTPRSPPLGLISRPRPSPLRSRID
PWSFVSAGPRPSPLPSPQPAPRRAPWTLFPDSDPFWDSPPANPFRGGSQDCRTQTKDMGA
QAPWAPEAGP
NT seq 2553 nt   +upstreamnt  +downstreamnt
atggagcccttgaagaacctcttcctcaagagcccgctggggtcatggaacggcagtggc
agtgggggcggcgggggtaccggtggagtccggccggaggggtctccgaaggcaacagca
gcttatgccaatcctgtctggacagccctgttcgactatgagcccaatgggcaggacgaa
ctagccctgaggaagggcgaccgtgtggaggtgctgtccagggatgcagccatctcagga
gatgagggctggtgggcgggccaggtgggtggccaggtgggcatttttccatccaactat
gtatctcggggtggaggcccacccccctgtgaggtggccagcttccaggagctgcgactg
gaggaggtgatcggcatcggtggcttcggcaaggtctaccgtggcagctggcgaggggag
ctggtggctgtgaaggcagcccgacaggaccctgatgaggacatcagtgtaacagctgag
agtgttcgacaggaggcccggctttttgccatgctggcccatcccaacatcattgccctc
aaagctgtgtgcctggaggagccaaacctatgcctggtgatggagtatgcagctggtggg
cctcttagccgggccctggctggtcggcgtgtgcccccccatgtgctggtcaactgggct
gtgcagattgcccgaggaatgcactacctgcactgtgaggctctggtgcctgtgatacac
cgagacctgaagtccaacaacattctgttgctgcagcccatcgagggtgacgacatggaa
cacaagaccctaaagattactgacttcggcctcgcccgagagtggcacaaaaccacccag
atgagtgctgcgggcacctacgcttggatggctcccgaggttatcaaggcctccaccttc
tccaagggcagcgacgtctggagctttggagtgctgctgtgggaactgctgactggggag
gtgccctaccgtggcatcgactgtcttgccgtagcctatggtgtggctgtaaacaagtta
acgttacccatcccatctacctgccctgagccctttgcacaactcatggctgactgctgg
gcacaggacccccaccgcaggcccgacttcgcctccatcctgcagcagttggaagctcta
gaagcgcaggtgctgcgggagatgccacgggactccttccattccatgcaggaaggctgg
aaacgcgagatccagggcctgtttgatgagctgcgggccaaggaaaaggaactactgagc
cgggaggaggaactgacgcgcgctgcacgtgagcagcggtcccaggcggagcagctgcga
cggcgcgagcacctgctggcgcagtgggagctggaggtgttcgagcgcgagctgacgctg
ctactgcagcaggtggaccgagaacggccgcacgtgcgccgccgccggggcaccttcaag
cggagcaaactccgagcaagggacggcggagaacgcatcagcatgcccctggatttcaaa
caccgcatcacagtgcaagcctctcctggcctggatcggaggagaaacgtgttcgaggtt
ggggctggggactcgcccaccttccctagattccgagccatccagttggaacctacagaa
tcaggccagacttggggtcgccagtcccccagacgtcttgaagattcaagcaatggagag
aggcgtgcttgctgggcctggggtcccagctcccccaagcctggggaggcccagaacggg
aggagacggtcccgcatggatgaagccacgtggtacctagattcagacgactcgtcccca
ttagggtcccctagtactcccccggcactcaacggtaatcctccaaggcctagccccgag
ccagaggagccacggagggccgggcccacggagcgaggcaatagctctgggacgcctaaa
ctgatccaacgtgcattgctacgggggaccgctctgctggcttccctaggccttggccga
gatctgcaacctccaggaggcctgagccgtgaacgcggggagtccccgacagcaccaccc
cctgcacagatgccctcaccctgcccacctgagctgccctccaccccgctcatccgcctc
tcacaaacaacacctgatgcccatagttcacccactcctggacccttattgctagaccta
ggtgttccctctggccagccatcagccaagagccctcgacgggaagagacacgtgggaga
accgtctcacccccaccaggaatatcacgctctgctcctggcacacctggaacccctcgc
tcaccaccgttgggcctaatcagccgacctcggccctcaccactccgtagccgtattgac
ccatggagcttcgtgtcagctgggccacggccttcacccctgccctctccacagcctgca
ccccgacgggcaccgtggaccttattcccagactcagatcccttctgggactccccacct
gccaaccccttccggggaggctcccaggactgcaggacgcagaccaaagacatgggtgcc
caggccccatgggcaccagaagcagggccctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (41)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (35)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (38)   
   RefSeq(nuc) (8)   
   GenBank (15)   
   EMBL (15)   
Protein domain (7)   
   Pfam (7)   
All databases (102)   

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