KEGG   Mus musculus (house mouse): 26404
Entry
26404             CDS       T01002                                 
Symbol
Map3k12, DLK, MUK, Zpk
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 12
  KO
K04423  mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    26404 (Map3k12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    26404 (Map3k12)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     26404 (Map3k12)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: TKL group
  MLK family
   26404 (Map3k12)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Pkinase_fungal ABC1
Other DBs
NCBI-GeneID: 26404
NCBI-ProteinID: NP_001157115
MGI: 1346881
Ensembl: ENSMUSG00000023050
UniProt: Q60700
Position
15:complement(102406079..102425311)
AA seq 888 aa
MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGG
GGPSPSPGGEPPPEPFANSVLQLHEQDTGGPGGATGSPESRASRVRADEVRLQCQSGSGF
LEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGE
EVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRP
VTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK
MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL
HLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWR
EEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALM
LQLELKERELLRREQALERRCPGLLKSHPSRGLLHGNTMEKLIKKRNVPQKLSPHSKRPD
ILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLPGLRAALP
PHEPGGLGSPGGLGVGPSAWDACPPALRGLHHDLLLRKMSSSSPDLLSAALGARGRGATG
GARDPGSPPPPQGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTAG
RGGNRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELPPSQRWPQGPNMRQS
LSTFSSENPSDVEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDLPTSEV
VPEREASSLPMQHQDGQGPNPEDSDCDSTELDNSNSIDALRPPASLPP
NT seq 2667 nt   +upstreamnt  +downstreamnt
atggcctgcctccatgaaacccgaacaccctccccttcctttgggggctttgtgtctact
ctaagtgaggcttctatgcgaaagctggatccagacacttcagactgcacccccgagaaa
gacctgacgcccacccaatgtgtacttcgagatgttgtgcctctcggtgggcagggtgga
ggaggacccagcccctccccaggtggagagcctcccccagagccttttgccaatagtgtc
ctccagctacatgagcaggatacaggtgggccagggggagccactgggtcacctgagagt
cgagcatctagagttcgagctgatgaggtacgtctgcagtgccagagtggcagtggcttc
cttgaaggtctttttggctgcctgcgccctgtctggacaatgattggcaaagcctactcc
acagaacacaagcaacagcaggaagacctttgggaagtcccctttgaggaaatcctggac
ctgcagtgggtaggctcaggggctcagggtgctgttttcctgggacgcttccacggggag
gaggtagctgtgaagaaggttcgagatctcaaggagactgacatcaagcatcttcgaaag
ctgaagcaccccaacatcatcactttcaagggtgtttgcacacaggccccctgctactgc
atccttatggaattctgcgctcaaggacagctatatgaggtgctcagagccggccgccct
gtcaccccctccttgctggttgactggtccatgggcatcgctggtggcatgaattacctg
cacctgcacaagattatccacagagacctgaagtcacccaacatgctaatcacatacgac
gatgtggtgaagatctcagattttggcacttccaaggagctgagtgacaagagcaccaag
atgtcctttgcaggaacagtagcctggatggctcctgaagtgatcagaaatgaacctgtg
tctgagaaggttgacatctggtcctttggggtggtgctatgggaactactgactggagag
attccctacaaagatgtagattcctcagccatcatctggggtgtgggaagcaacagtctc
cacctgcctgtaccctccagctgcccagatggttttaaaattctacttcgccagtgctgg
aacagcaaaccacgaaatcgcccatcattccgacagatcttgctgcacctggacatcgcc
tccgctgatgtgctctctacaccccaggagacttactttaagtcccaggcagagtggcgg
gaagaagtaaaactgcactttgaaaagattaagtcagaagggacctgtctgcaccgccta
gaagaggaactggtgatgcggagaagggaggagctcagacatgccctggacatcagggag
cactatgaacggaagttggagagagccaacaacctgtacatggaactgaatgccctcatg
ctgcaactagaactcaaagagagggaattgctcaggcgagagcaggctttagaaaggcgg
tgtcctggtctactaaagtcacacccttctcggggcctcctacatggaaacactatggag
aagctcatcaagaaaaggaacgtgccacagaaactgtcgccccacagcaaaaggccagat
attctcaagacagagtcgttgctacctaaactagatgcagccctaagtggggtggggctt
cctgggtgtcctaagggccccccttcacctggaaggagtcggcgtggcaagacccgtcac
cgaaaggccagtgccaagggcagctgtggagacctgcctgggcttcgtgcagctttgcca
ccccatgagcctggaggactaggaagcccagggggcctaggagtgggcccttcagcttgg
gatgcttgcccccctgctctccgtggactccaccatgaccttctactccgaaagatgtca
tcatcatccccagacctgctatcagcagcgctgggagcccgaggccgaggggctacaggg
ggagctcgggatcctggctcaccacctccaccccagggcgatactcctccaagtgaggga
tcagctcctggttccaccagcccagattcgcctgggggagctaaaggggaaccccctcca
ccagtagggcctggagaaggtgtggggctgctgggaactggaagggaagggactgcaggc
cggggaggaaaccgggctgggtcccagcacttgacccccgctgcgctgctgtacagggct
gctgtgactcgaagtcagaaacgtggtatctcatctgaagaagaagaaggagaggtagac
agtgaagtagagctacccccaagtcaaaggtggcctcagggcccgaacatgcgtcagtca
ctatctacattcagctcagagaacccatcagatgtggaggaaggtacagctagtgagcct
tccccaagtggcacaccagaagttggcagtaccaacactgatgagcgaccagatgaacga
tctgatgacatgtgctcacagggctcagaaattccactggacctacctacttcagaggtg
gtccctgaacgtgaagccagctccttgcccatgcaacaccaggatggccagggccccaat
cctgaagactcagactgtgacagcactgaattggacaactccaacagcattgatgccttg
cggcccccagcctcccttcctccatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (36)   
   RefSeq(nuc) (10)   
   GenBank (13)   
   EMBL (13)   
Protein domain (4)   
   Pfam (4)   
All databases (79)   

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