KEGG   Mus musculus (house mouse): 26406
Entry
26406             CDS       T01002                                 
Symbol
Map3k3, MAPKKK3, Mekk3, mKIAA4031
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 3
  KO
K04421  mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04722  Neurotrophin signaling pathway
mmu04912  GnRH signaling pathway
mmu05166  Human T-cell leukemia virus 1 infection
mmu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    26406 (Map3k3)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    26406 (Map3k3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    26406 (Map3k3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    26406 (Map3k3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    26406 (Map3k3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    26406 (Map3k3)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     26406 (Map3k3)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: STE group
  STE11 family
   26406 (Map3k3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PB1 ABC1 Kinase-like FTA2
Other DBs
NCBI-GeneID: 26406
NCBI-ProteinID: NP_036077
MGI: 1346874
Ensembl: ENSMUSG00000020700
UniProt: Q61084
Position
11:105975358..106047482
AA seq 626 aa
MDEQEALDSIMKDLVALQMSRRTRLSGYETMKNKDTGHPNRQSDVRIKFEHNGERRIIAF
SRPVRYEDVEHKVTTVFGQPLDLHYMNNELSILLKNQDDLDKAIDILDRSSSMKSLRILL
LSQDRNHTSSSPHSGVSRQVRIKPSQSAGDINTIYQAPEPRSRHLSVSSQNPGRSSPPPG
YVPERQQHIARQGSYTSINSEGEFIPETSEQCMLDPLSSAENSLSGSCQSLDRSADSPSF
RKSQMSRARSFPDNRKECSDRETQLYDKGVKGGTYPRRYHVSVHHKDYNDGRRTFPRIRR
HQGNLFTLVPSSRSLSTNGENMGVAVQYLDPRGRLRSADSENALTVQERNVPTKSPSAPI
NWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQ
HERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYL
HSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWMSPEVIS
GEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFL
RRIFVEARQRPSAEELLTHHFAQLVY
NT seq 1881 nt   +upstreamnt  +downstreamnt
atggatgaacaagaggcattagactcgatcatgaaggacctggtggccctccagatgagc
cgacgaacccggttgtctggatatgagaccatgaagaataaggacacaggtcacccaaac
aggcagagtgacgtcagaatcaagtttgaacacaatggggagagacgaattatagcattc
agccggcctgtgagatacgaagatgtggagcacaaggtgacaacagtctttgggcagcct
cttgatttgcattatatgaataatgagctctccatcctgttgaaaaaccaagatgatctc
gataaagccattgacattttggatagaagctcaagtatgaaaagccttaggatactactg
ttatcccaagacagaaaccatactagttcctctccccactctggagtgtccaggcaggtt
cggatcaagccttcccagtctgcaggggatataaataccatctaccaagctcctgagccc
agaagcaggcacctgtctgtcagctcccagaaccctggccgaagctctcctcccccggga
tatgtacctgagcgacaacagcacattgcccggcaaggatcctatacgagcatcaacagc
gaaggtgaattcatcccagagaccagcgaacagtgtatgctagatcccctcagcagtgcc
gaaaattccttgtcaggaagctgccaatccttggacaggtcagcagacagcccatccttc
aggaaatcacaaatgtcccgagcccggagcttcccagacaacagaaaggaatgctcagat
cgggagacccagctctatgataaaggtgtcaaaggtggaacctatcccaggcgctaccat
gtgtctgtgcatcacaaagactacaatgatggcagaagaacatttccccgaatacgacgg
catcaaggcaacctattcactctggtgccctcaagtcgctccttgagcacaaatggcgag
aacatgggtgtagctgtgcaatacctggacccccgtgggcgcctacggagtgcagacagt
gagaatgccctcactgtgcaggaaaggaatgtgccaaccaaatctcctagtgctcccatc
aattggcgtcgggggaagctcctgggtcaaggtgccttcggcagggtctacttgtgctat
gatgtggacacaggacgtgaacttgcttctaagcaggtccagtttgacccagatagtcct
gagacaagcaaggaggtgagtgctctggagtgtgagatccagttgctgaagaacctgcag
catgagcgcattgtgcagtactacggctgcctgcgggaccgtgctgagaagatcctcacc
atctttatggagtatatgccagggggctctgtaaaagaccagttgaaggcctacggagct
ctgacagagagtgtgacccgcaagtacacccggcagattctggagggcatgtcatacctg
cacagcaacatgattgtgcatcgggacatcaagggagccaatatcctccgagactcagct
gggaatgtgaagcttggggattttggggccagcaaacgcctacagaccatctgcatgtca
gggacaggcattcgctctgtcactggcacaccctactggatgagtcctgaagtcatcagt
ggcgagggctatggaagaaaggcagacgtgtggagcctgggctgtactgtggtggaaatg
ctgacagagaaaccaccttgggcagagtatgaagctatggctgccattttcaagattgcc
acccagcctaccaatcctcagctgccctctcacatctcagaacacggcagggacttcctg
aggcgcatatttgtggaagctcgtcagagaccctcagctgaggagctgctcacacaccac
tttgcacagctagtgtactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (15)   
   RefSeq(nuc) (5)   
   GenBank (5)   
   EMBL (5)   
Protein domain (6)   
   Pfam (6)   
All databases (48)   

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