KEGG   Mus musculus (house mouse): 269523
Entry
269523            CDS       T01002                                 
Symbol
Vcp, 3110001E05, CDC48, p97, p97/VCP
Name
(RefSeq) valosin containing protein
  KO
K13525  transitional endoplasmic reticulum ATPase
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04137  Mitophagy - animal
mmu04141  Protein processing in endoplasmic reticulum
mmu05014  Amyotrophic lateral sclerosis
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05134  Legionellosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    269523 (Vcp)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    269523 (Vcp)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05134 Legionellosis
    269523 (Vcp)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    269523 (Vcp)
   05022 Pathways of neurodegeneration - multiple diseases
    269523 (Vcp)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    269523 (Vcp)
   03009 Ribosome biogenesis [BR:mmu03009]
    269523 (Vcp)
   04131 Membrane trafficking [BR:mmu04131]
    269523 (Vcp)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    269523 (Vcp)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Ran-mediated transport factors
     269523 (Vcp)
Ribosome biogenesis [BR:mmu03009]
 Eukaryotic type
  Pre-60S particles
   Ribosome quality control proteins
    269523 (Vcp)
Membrane trafficking [BR:mmu04131]
 SNARE
  SNARE associated proteins
   Others
    269523 (Vcp)
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    269523 (Vcp)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   269523 (Vcp)
SSDB
Motif
Pfam: AAA AAA_lid_3 CDC48_N RuvB_N AAA_16 CDC48_2 AAA_5 AAA_33 AAA_2 AAA_22 TIP49 AAA_14 RNA_helicase AAA_28 Vps4_C nSTAND3 AAA_18 Parvo_NS1 Mg_chelatase AAA_17 ATPase_2 IstB_IS21 AAA_7 ATPase DUF815 Bac_DnaA ABC_tran AAA_24 NB-ARC ResIII TsaE Zeta_toxin NACHT Sigma54_activat Viral_helicase1 SLFN-g3_helicase bpMoxR KAP_NTPase Zot UFD1 DUF3944
Other DBs
NCBI-GeneID: 269523
NCBI-ProteinID: NP_033529
MGI: 99919
Ensembl: ENSMUSG00000028452
UniProt: Q01853
Structure
Position
4:complement(42979964..43000507)
AA seq 806 aa
MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLK
GKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPID
DTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDT
VIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRG
ILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAI
IFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRF
GRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAAL
QAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIG
GLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFI
SIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRV
INQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKAN
LRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAM
EVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGG
AGPSQGSGGGTGGSVYTEDNDDDLYG
NT seq 2421 nt   +upstreamnt  +downstreamnt
atggcctctggagccgattcaaaaggtgatgatttatcaacagccattctcaaacagaag
aaccgacccaatcggttaattgttgatgaagccatcaatgaagataacagcgtggtgtcc
ttgtcccagcccaagatggatgaactgcagttgttccgaggtgacacggtgttgctaaaa
ggaaagaaaagacgggaagctgtatgcattgttctttctgatgacacgtgttctgatgag
aagattcgaatgaatagagttgttcggaataacctccgagttcgcctaggagatgtcatc
agcatccagccatgccctgatgtaaagtatggcaaacgtatccacgttctacccatcgat
gacacagtggaaggcatcactggcaatctctttgaggtataccttaagccgtacttcctg
gaagcttatcggcccatccgtaaaggagatatttttcttgtccggggtgggatgcgtgct
gtggagttcaaagttgtagagacagatcccagcccttactgtattgttgctccagacaca
gtgatccactgtgagggggagccaatcaagcgagaggatgaggaggaatccttgaatgaa
gtaggctatgatgacatcggtggttgcaggaagcagctagctcagataaaggagatggtg
gagctgccactgagacatcctgcgctctttaaggcgattggtgtaaagcctcctcgggga
atcttgttgtatgggcctcctgggacagggaagaccctgattgctcgagctgtggcaaat
gaaactggagccttcttctttctgatcaatggtcctgaaatcatgagcaaattggctggt
gagtctgagagcaaccttcgtaaagcctttgaggaagctgaaaagaatgctcctgctatc
atcttcatcgatgagcttgatgccattgcacccaaaagagagaaaactcatggggaagtg
gagcgtcgcatcgtgtctcagttgttgaccctcatggatggcctaaagcagagagcacat
gtgatagttatggcagcaaccaatagacccaacagcattgacccagccctacggcgattt
ggtcgctttgacagagaggtagatattggaatacctgatgctacaggacgtttggagatt
cttcagatccataccaagaacatgaaactggcagatgatgtggacttggaacaggtagcc
aatgagactcatggtcatgttggtgctgatttggcagccctatgttcagaggctgctctg
caggccatccggaaaaaaatggacctcattgacctagaagatgagaccattgatgctgag
gtcatgaattccctggcagttactatggatgacttccggtgggctttgagtcaaagcaac
ccatcagcacttcgggaaactgtggtagaggtgccacaagtaacctgggaagatattgga
ggcctggaggatgtcaaacgtgagcttcaggagttggttcagtatcctgtggaacatcca
gacaaattcctcaaatttggcatgactccctccaaaggcgttcttttctatggacctcct
ggctgtgggaaaaccttactggctaaagccattgctaatgaatgccaggccaacttcatc
tccatcaagggtcctgagctgcttaccatgtggtttggggaatctgaggccaatgtccgg
gaaatttttgacaaggcacggcaagctgccccctgtgtactcttctttgatgagttagat
tcaattgccaaggctcgaggtggtaatattggagatggtggtggagctgctgaccgagtc
atcaatcagatcctgacagaaatggatggcatgtctacaaaaaagaatgtgtttatcatt
ggagctaccaacaggcctgacatcattgatcctgctatcctaagacctggccgtctagat
cagctcatttatatcccacttcctgatgagaagtcccgtgttgccatcctaaaagccaat
ctgcgaaagtccccagttgccaaggatgtggatttggagttcctggctaagatgactaat
ggcttttctggagctgatttgacagaaatttgccaacgggcttgtaaactggccattcgt
gaatctattgagagtgagattaggcgagaacgagagaggcagacaaatccatcggctatg
gaggtagaagaggacgatccagtgcctgagatccgcagagatcactttgaggaagccatg
cgttttgcccgacgttctgtcagcgataatgacattcggaagtatgaaatgttcgcccag
acactgcagcagagtcgaggttttggcagcttcagattcccttcagggaaccagggtgga
gctggtcccagccagggcagtggaggtggcacaggtggcagtgtgtacacagaagacaat
gacgatgacctgtatggctaa

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (5)   
   KEGG PATHWAY (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (79)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (71)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (283)   
   RefSeq(nuc) (1)   
   GenBank (141)   
   EMBL (141)   
3D Structure (8)   
   PDB (8)   
Protein domain (41)   
   Pfam (41)   
All databases (425)   

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