KEGG   Mus musculus (house mouse): 271849
Entry
271849            CDS       T01002                                 
Symbol
Shc4, 6230417E10Rik, 9930029B02Rik, Gm685, RaLP
Name
(RefSeq) SHC (Src homology 2 domain containing) family, member 4
  KO
K17449  SHC-transforming protein 4
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu01522  Endocrine resistance
mmu04012  ErbB signaling pathway
mmu04014  Ras signaling pathway
mmu04062  Chemokine signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04510  Focal adhesion
mmu04650  Natural killer cell mediated cytotoxicity
mmu04722  Neurotrophin signaling pathway
mmu04910  Insulin signaling pathway
mmu04915  Estrogen signaling pathway
mmu04917  Prolactin signaling pathway
mmu04926  Relaxin signaling pathway
mmu04935  Growth hormone synthesis, secretion and action
mmu05034  Alcoholism
mmu05100  Bacterial invasion of epithelial cells
mmu05206  MicroRNAs in cancer
mmu05214  Glioma
mmu05220  Chronic myeloid leukemia
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    271849 (Shc4)
   04014 Ras signaling pathway
    271849 (Shc4)
   04072 Phospholipase D signaling pathway
    271849 (Shc4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    271849 (Shc4)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    271849 (Shc4)
   04062 Chemokine signaling pathway
    271849 (Shc4)
  09152 Endocrine system
   04910 Insulin signaling pathway
    271849 (Shc4)
   04915 Estrogen signaling pathway
    271849 (Shc4)
   04917 Prolactin signaling pathway
    271849 (Shc4)
   04926 Relaxin signaling pathway
    271849 (Shc4)
   04935 Growth hormone synthesis, secretion and action
    271849 (Shc4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    271849 (Shc4)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    271849 (Shc4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    271849 (Shc4)
   05226 Gastric cancer
    271849 (Shc4)
   05214 Glioma
    271849 (Shc4)
   05220 Chronic myeloid leukemia
    271849 (Shc4)
   05224 Breast cancer
    271849 (Shc4)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    271849 (Shc4)
  09165 Substance dependence
   05034 Alcoholism
    271849 (Shc4)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    271849 (Shc4)
   01522 Endocrine resistance
    271849 (Shc4)
SSDB
Motif
Pfam: PID SH2 Delta_lysin
Other DBs
NCBI-GeneID: 271849
NCBI-ProteinID: NP_950187
MGI: 2655364
Ensembl: ENSMUSG00000035109
UniProt: Q6S5L9 Q8CB26
Position
2:complement(125469359..125566085)
AA seq 626 aa
MRERSQDSQAGLTLYVGLFGHLGMLHRTKYSRFRNESITSLDEGSPGGSVGNKGSSPPPY
PALAPHLPTEDATVSSQESPTALCTLIPRMASMKLANPITFLGLKTFCLGTKQVSRLKLQ
ENQDQTPSRPASPESNLNRTGPAPAPDPDQVGRRPTSLRPDTCPLPGPGEPSPRSKQDGP
PLQHLLGNGLNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGAHGAIKKRK
APVKFLTTVLGKSNLQFSGMNIKLTVSTSSLTLMNLDNQQIIANHQMQSISFASGGDPDT
TDYVAYVAKDPVNQRACHILECRSGMAQDVISTIGQAFELRFKQYLKNPSLNTWEREEVL
VDGAPEDRDHDYYNSIPGKQPPEGGISDVRIQAQATDQMAYCPIRCEKLCYLPGNSTCSG
VYKNCMGRSRPIGIPHERAGQGDTPSLRHFWRVDLFDDPCYVNTQALQSMHSYAGNQSSA
LPQGSPWHLGKAPETVQPGATAKPGSALALPHIRQQLWDEECFHGKLSRGAAEKLLVKDG
DFLVRESVTSPGQFVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNNLPI
ISSGSEVRLKQPIRKYDNTGLLPPKK
NT seq 1881 nt   +upstreamnt  +downstreamnt
atgcgagaacgcagccaggacagccaggcaggactcacgctgtatgtaggactctttggg
cacctggggatgcttcacaggaccaagtacagccgctttcggaacgagtccatcacgtct
ttggacgaagggagccccggaggctccgttggaaacaagggctcgtcgccgcctccctac
ccagccctggcccctcacctgccgactgaggatgccactgtgtccagccaggagagcccc
acggcgctgtgcaccttgattccccgtatggcaagcatgaagctggccaaccccatcact
tttctgggtctgaaaaccttctgcttgggtacgaaacaggtgagccggttgaagctccaa
gagaaccaggatcagactccaagccgtccagcgtccccagaatccaatctaaacaggact
ggacctgcacctgcaccggatccggaccaggtgggacgcaggcccacctctttgcgtcct
gatacttgcccactgcctggccctggagaaccaagccccaggagcaagcaggacgggccc
cctctgcagcacctgttggggaacggtctgaactactgtgtgcggtacatgggctgcatt
gaagtgctgcaatcaatgaggtcactggattttggaatgagaacccaagttacaagggaa
gcaataagtcgcctgtgtgaagctgtccccggggcccatggagccattaaaaaacgaaag
gctcccgttaagttcctgacaacggttcttggcaaaagcaatcttcagttttcaggaatg
aatataaaactgactgtttcaacaagcagcctcacactgatgaaccttgacaaccaacag
attattgcaaatcaccaaatgcaatcgatttcatttgcctctggaggggaccctgatacc
acagactatgttgcctatgtagctaaagatccagtcaaccaacgagcgtgccacatactg
gagtgtcgcagtggaatggcccaagacgtcataagcaccatagggcaggcctttgaactc
cggttcaaacagtacttgaaaaatccttccttgaacacttgggaaagggaggaggtactt
gttgatggtgcccctgaagacagagaccatgactattacaactccatcccggggaagcag
ccacctgaaggcggcatttcagatgtgcgcatccaggctcaagctacagaccaaatggca
tactgccctatccggtgtgaaaagttgtgctatttgcctgggaactccacgtgcagcggt
gtgtataagaactgtatgggacggagcaggccaataggtatcccgcacgagagagcgggg
cagggtgacacaccatcgctgaggcacttctggagagtggatctctttgacgacccctgc
tatgtcaatacacaggctcttcagagtatgcacagctatgctggaaatcaaagctcagct
ctgccacaggggagcccctggcacctcggaaaggcaccagaaactgtgcagcctggagcc
acggccaagcctgggagcgcactcgctttgccacacattaggcagcagctgtgggacgag
gagtgcttccatggcaagctgagcagaggggcagcggagaaacttttggtgaaggatggg
gactttttggttcgagagagtgtgacatctcccggccagtttgtactgagtggactgcaa
ggtggccaggccaagcatcttctcttggtggatccagaaggcaaggtgaggaccaaggac
catgtgtttgataatgttggccaccttatcaaataccatatggataataatttgccaatc
atctcttctggaagtgaagtacgccttaaacaaccaataagaaaatatgataacacagga
cttttgccccccaagaaatga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (22)   
   KEGG PATHWAY (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (17)   
   RefSeq(nuc) (3)   
   GenBank (7)   
   EMBL (7)   
Protein domain (3)   
   Pfam (3)   
All databases (64)   

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