KEGG   Mus musculus (house mouse): 27390
Entry
27390             CDS       T01002                                 
Symbol
Mmel1, Mell1, NEP2, NEP2(m), NEPII, NL-1, NL2, Nl1, SEP
Name
(RefSeq) membrane metallo-endopeptidase-like 1
  KO
K08635  neprilysin [EC:3.4.24.11]
Organism
mmu  Mus musculus (house mouse)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    27390 (Mmel1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.11  neprilysin
     27390 (Mmel1)
Peptidases and inhibitors [BR:mmu01002]
 Metallo peptidases
  Family M13: neprilysin family
   27390 (Mmel1)
SSDB
Motif
Pfam: Peptidase_M13_N Peptidase_M13 ERAP1_C Kdo TerB_N
Other DBs
NCBI-GeneID: 27390
NCBI-ProteinID: NP_038811
MGI: 1351603
Ensembl: ENSMUSG00000058183
UniProt: Q9JLI3 E9PVK7
Position
4:154954042..154979987
AA seq 766 aa
MVERAGWCRKKSPGFVEYGLMVLLLLLLLGAIVTLGVFYSIGKQLPLLTSLLHFSWDERT
VVKRALRDSSLKSDICTTPSCVIAAARILENMDQSRNPCENFYQYACGGWLRHHVIPETN
SRYSVFDILRDELEVILKGVLEDSTSQHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLSVL
KMVGGWPVAMDKWNETMGLKWELERQLAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYIDQ
PTLGMPSREYYFQEDNNHKVRKAYLEFMTSVATMLRKDQNLSKESAMVREEMAEVLELET
HLANATVPQEKRHDVTALYHRMDLMELQERFGLKGFNWTLFIQNVLSSVEVELFPDEEVV
VYGIPYLENLEDIIDSYSARTMQNYLVWRLVLDRIGSLSQRFKEARVDYRKALYGTTVEE
VRWRECVSYVNSNMESAVGSLYIKRAFSKDSKSTVRELIEKIRSVFVDNLDELNWMDEES
KKKAQEKAMNIREQIGYPDYILEDNNKHLDEEYSSLTFYEDLYFENGLQNLKNNAQRSLK
KLREKVDQNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKDQPQSLNFGGIGMVIGH
EITHGFDDNGRNFDKNGNMLDWWSNFSARHFQQQSQCMIYQYGNFSWELADNQNVNGFST
LGENIADNGGVRQAYKAYLRWLADGGKDQRLPGLNLTYAQLFFINYAQVWCGSYRPEFAV
QSIKTDVHSPLKYRVLGSLQNLPGFSEAFHCPRGSPMHPMKRCRIW
NT seq 2301 nt   +upstreamnt  +downstreamnt
atggtggagagagcaggctggtgtcggaagaagtccccaggcttcgtggagtatgggctg
atggtgctgctgctgctgctgttgctgggagccatagtgactctgggtgtcttctacagc
atagggaagcagctgcccctcttaactagcctgctacacttctcctgggatgagaggacg
gttgtaaaacgagccctcagggattcatcactgaaaagtgacatctgcaccaccccaagc
tgtgtgatagcagctgccagaatcctcgaaaacatggaccaatcgaggaacccctgtgaa
aacttctaccagtacgcttgcggaggctggctgaggcaccacgtgatcccagagaccaac
tccagatacagcgtctttgacatccttcgggacgagctggaggttatcctcaaaggggtg
ctggaggattccacttcccagcatcgcccggccgtggagaaggccaagacactatatcgc
tcctgcatgaaccaaagtgtgatcgagaagagagactctgagcccctgctgagcgtctta
aaaatggtaggaggttggcctgtggccatggataagtggaacgagaccatgggcctcaag
tgggaactggagcgacagttggctgtgttgaactcgcagttcaacaggcgggtcctcatc
gacctcttcatctggaatgacgaccagaactccagccggcatgtcatctacatagaccag
cccaccttgggcatgccatcccgggagtactatttccaggaggacaacaaccacaaggta
cggaaagcctacctggagttcatgacgtcagtggccactatgcttaggaaagaccagaac
ctgtccaaggagagcgccatggtgcgggaggagatggcggaggtgctggaactggagacg
catctggccaacgccacagtcccccaggagaaaaggcatgatgtcactgccctgtaccac
cgaatggacctgatggagctacaggaaaggtttggtctgaaggggtttaactggactctc
ttcatacaaaacgtgttgtcttctgtggaagtcgagctgttcccagatgaggaggtggtg
gtctacggcatcccctacctggagaatctggaggatatcattgatagctactcagcacgg
accatgcagaactacctggtatggcgcctggtgctagatcgaattggcagcctgagccag
agattcaaagaggcgcgtgtggactaccgcaaggcgctgtacggcacgaccgtggaggag
gtacgctggcgagagtgtgtcagctatgtcaacagtaacatggagagcgccgtgggctcc
ctctacatcaagcgggccttctccaaggacagcaagagcacggtcagagagctgattgag
aagataaggtccgtgtttgtggataacctggatgagctgaactggatggacgaggaatcc
aagaagaaggcccaggaaaaggccatgaatatacgggaacagattggctaccctgactac
attttggaagataacaataaacacctggatgaggaatactccagtttgactttctatgag
gacctgtattttgagaacggacttcagaacctcaagaacaatgcccagaggagcctcaag
aagcttcgggaaaaggtggaccagaatctctggatcatcggggctgcagtggtcaatgca
ttctactccccaaacagaaaccagatcgtctttccagcagggattctccagccgcccttc
ttcagcaaggaccaaccacagtccttgaattttgggggcatcgggatggtgattgggcac
gagatcacacacggctttgatgataatggtcgtaactttgacaagaacggcaacatgctg
gactggtggagtaacttctcggcccggcacttccaacagcagtcgcaatgcatgatctat
cagtacggcaacttctcttgggaactagcagacaaccagaatgtgaacggattcagtacc
ctcggggagaacattgccgacaacggaggtgtgcgacaggcatacaaggcttacctacgg
tggctggctgatggcggcaaagatcagcgactgccgggactgaacctgacctatgcccag
cttttcttcatcaactatgcccaggtgtggtgtgggtcctataggccggagttcgccgtc
cagtccatcaagacggacgtccacagtcctcttaagtacagggtgctgggctcactacag
aacctgccaggcttctctgaggcattccactgcccacgaggcagccccatgcaccccatg
aagcgatgtcgcatctggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (5)   
   Pfam (5)   
All databases (51)   

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