KEGG   Mus musculus (house mouse): 27400
Entry
27400             CDS       T01002                                 
Symbol
Hsd17b6, 17betaHSD9, Hsd17b9, Rdh8
Name
(RefSeq) hydroxysteroid (17-beta) dehydrogenase 6
  KO
K13369  17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00140  Steroid hormone biosynthesis
mmu00830  Retinol metabolism
mmu01100  Metabolic pathways
mmu01240  Biosynthesis of cofactors
Module
mmu_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
mmu_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    27400 (Hsd17b6)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    27400 (Hsd17b6)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     27400 (Hsd17b6)
    1.1.1.105  all-trans-retinol dehydrogenase (NAD+)
     27400 (Hsd17b6)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     27400 (Hsd17b6)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR
Other DBs
NCBI-GeneID: 27400
NCBI-ProteinID: NP_038814
MGI: 1351670
Ensembl: ENSMUSG00000025396
UniProt: Q9R092
Position
10:complement(127826800..127843517)
AA seq 317 aa
MWFYLVTLVGLYHLLRWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAAC
LTEKGAEELRNKTSDRLETVILDVTKTESIVAATQWVKERVGDRGLWGLVNNAGVLQPFA
YIEWYRPEDYMPIFQVNLIGLTQVTISMLFLVKKARGRIVNVSSALGRVALFGGFYSCSK
YGVEAFSDVLRHEVQDFGVKVSIIEPGSFKTEMTDAELTIERTKKVWEAAPEHIKESYGQ
QFFDDFCSTTKRELMKCSRNLSLVTDCMEHALTSTHPRTRYSAGWDAKFFFIPLSYLPAS
LVDYLLAISRGKPAQAA
NT seq 954 nt   +upstreamnt  +downstreamnt
atgtggttctacctggtaactcttgtgggcctttaccaccttctgcgttggtatcgtgag
aggcaggtggtgagccatctccaagacaagtatgtcttcatcacgggctgtgactctggc
tttgggaacctgctggccagacagctggacaggagaggcatgagggtattggctgcatgt
ctgacggagaagggagccgaggagctgaggaacaagacatctgacaggctggagacagtg
atcctggatgtcaccaagacagagagtattgtggcagccactcagtgggtgaaggagcgt
gttggagacagaggactctggggtttggttaataatgcaggtgtgttacaaccatttgcc
tacattgaatggtacagaccagaggactacatgcctatctttcaagtgaacctcattggt
ttgacccaggtgactataagcatgcttttcctggtaaagaaggctcggggcaggatcgtc
aatgtctccagtgctttgggaagagttgcattgtttggaggattctacagttgctccaag
tatggggttgaggcattttcagatgtgctaaggcatgaggttcaagatttcggggtgaaa
gtcagcataattgaacctgggagcttcaagacggaaatgacagatgcagagttaaccatt
gagagaactaagaaagtctgggaagctgcccctgagcacatcaaggaatcctacggacag
cagttttttgacgacttttgcagcaccaccaaacgagagttgatgaagtgtagcaggaac
ctgagcctagtcacggactgcatggagcacgccctgacctccacgcatcctcgcacccgg
tactcggctggctgggatgccaagtttttcttcatccctctatcttatttgcctgcgtca
ctggtagactacttattggccatatctaggggcaagccagctcaagcagcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (21)   
   KEGG COMPOUND (21)   
Chemical reaction (14)   
   KEGG ENZYME (3)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (19)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (17)   
DNA sequence (23)   
   RefSeq(nuc) (19)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (97)   

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