KEGG   Mus musculus (house mouse): 29869
Entry
29869             CDS       T01002                                 
Symbol
Ulk2, A830085I22Rik, Unc51.2, mKIAA0623
Name
(RefSeq) unc-51 like kinase 2
  KO
K08269  serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04136  Autophagy - other
mmu04140  Autophagy - animal
mmu04150  mTOR signaling pathway
mmu05010  Alzheimer disease
mmu05014  Amyotrophic lateral sclerosis
mmu05016  Huntington disease
mmu05017  Spinocerebellar ataxia
mmu05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    29869 (Ulk2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    29869 (Ulk2)
   04136 Autophagy - other
    29869 (Ulk2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    29869 (Ulk2)
   05014 Amyotrophic lateral sclerosis
    29869 (Ulk2)
   05016 Huntington disease
    29869 (Ulk2)
   05017 Spinocerebellar ataxia
    29869 (Ulk2)
   05022 Pathways of neurodegeneration - multiple diseases
    29869 (Ulk2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    29869 (Ulk2)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    29869 (Ulk2)
   03029 Mitochondrial biogenesis [BR:mmu03029]
    29869 (Ulk2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     29869 (Ulk2)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  ULK family [OT]
   29869 (Ulk2)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Autophagosome formation proteins
   Atg1 complex
    29869 (Ulk2)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    29869 (Ulk2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ATG1-like_MIT1 ATG1-like_MIT2 Kdo ABC1 RIO1 Pkinase_fungal Kinase-like TcdA_TcdB
Other DBs
NCBI-GeneID: 29869
NCBI-ProteinID: NP_038909
MGI: 1352758
Ensembl: ENSMUSG00000004798
UniProt: Q9QY01 Q3UG39
Position
11:complement(61666424..61750754)
AA seq 1037 aa
MEVVGDFEYCKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKIL
KELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMR
ILHSKGIIHRDLKPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMY
MAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRET
SPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPVKKSCPVPVPVYSGPVPGSSCSSSP
SCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASNSSKNSSCDTDDFVLVPHNI
SSDHSYDMPMGTTARRASNEFFMCGGQCQPTVSPHSETAPIPVPTQVRNYQRIEQNLIST
ASSGTNPHGSPRSAVVRRSNTSPMGFLRVGSCSPVPGDTVQTGGRRLSTGSSRPYSPSPL
VGTIPEQFSQCCCGHPQGHEARSRHSSGSPVPQTQAPQSLLLGARLQSAPTLTDIYQNKQ
KLRKQHSDPVCPSHAGAGYSYSPQPSRPGSLGTSPTKHTGSSPRNSDWFFKTPLPTIIGS
PTKTTAPFKIPKTQASSNLLALVTRHGPAESQSKDGNDPRECSHCLSVQGSERHRSEQQQ
SKAVFGRSVSTGKLSEQQVKAPLGGHQGSTDSLNTERPMDVAPAGACGVMLALPAGTAAS
ARAVLFTVGSPPHSATAPTCTHMVLRTRTTSVGSSSSGGSLCSASGRVCVGSPPGPGLGS
SPPGAEGAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNMMLMFTEC
VLDLTAVRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASL
HLAKAQVKSGKLSPSMAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSV
TAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSKILQDPTDVENVHKYK
CSIERRLSALCCSTATV
NT seq 3114 nt   +upstreamnt  +downstreamnt
atggaggtggtgggcgacttcgagtactgcaagcgggacctcgtgggacacggggccttc
gctgtggtcttccgggggcggcaccgccagaaaactgattgggaggtggctattaaaagt
attaataaaaagaacttgtcaaaatcacaaattctgcttggaaaggaaataaaaatctta
aaggagcttcagcatgaaaacatcgtagcgctctatgatgttcaggaattgcccaactct
gtctttctggtgatggagtattgcaatggtggagacctggcagattatttgcaagctaaa
ggaactctgagtgaagatactatcagagtgtttctccatcagattgcggcagccatgcga
atcctgcacagcaaagggataatccacagggatctcaaaccacagaatatcctgttgtct
tatgccaatcgaaggaagtcgaatgtcagtggtattcgtattaaaatagctgattttggt
ttcgcacggtacctacatagtaacacaatggcagcgacactgtgtggatccccaatgtac
atggctcccgaggttattatgtctcaacattatgatgctaaggcagatttatggagcata
ggaacagtgatctatcaatgcctagttggaaaaccaccttttcaggctaatagtcctcag
gacctaaggatgttttatgaaaaaaacaggagcttaatgcctagtattcccagagaaaca
tcaccttacttggctaatctccttttgggtttgcttcagagaaatcaaaaggatagaatg
gactttgaagcatttttcagccatcctttccttgagcaagttccagttaaaaaatcttgc
ccagtcccagtgcctgtgtattctggccctgtccctggaagctcctgcagcagctcacca
tcttgtcgctttgcttctccaccatcccttccagatatgcagcatattcaggaagaaaac
ttatcctccccaccgttgggtcctcccaactatctacaggtgtccaaagactctgcgagt
aatagtagcaagaactcttcttgtgacacggatgactttgttttggttccacacaacatc
tcgtcagaccactcatatgacatgccaatggggactacggccagacgtgcttcaaatgaa
ttctttatgtgtggagggcagtgtcaacctactgtgtcacctcacagcgaaacagcccca
attccagttcctactcaagtaaggaattatcagcgcatagaacagaatcttatatccact
gccagctctggcacaaacccacatggttctccaagatctgcagtagtacgaaggtctaat
accagccccatgggcttcctccgggttgggtcctgctcccctgtaccaggagacacagtg
cagacaggaggacgaagactctctactggctcttccaggccttactcaccatcccctttg
gttggtaccattcctgaacagtttagtcagtgctgctgtggacatcctcagggccatgaa
gccaggagtaggcactcctcaggttctccagtgccacagacccaggcaccacagtcactc
ttactgggtgctagactgcagagtgcacccaccctcaccgatatctatcagaacaagcag
aagctcagaaagcagcactctgaccctgtgtgtccgtcccatgctggagctgggtatagt
tactcacctcagcctagtcggcctggcagccttgggacctctcccaccaagcacacgggg
tcctctccacggaattctgactggttctttaaaactcctttaccaacaatcattggctct
cctactaagactacagctcctttcaaaatccctaaaacacaagcatcttctaacctgtta
gccttggttactcgtcatgggcctgctgaaagccagtccaaagatgggaatgaccctcgt
gagtgttcccactgcctctcagtacaaggaagcgagaggcatcgatctgagcagcagcag
agcaaggcagtgtttggcagatctgtcagtactgggaagttatcagaacaacaagtaaag
gcacctttaggtggacaccagggcagcacggatagtttaaacacagaacgaccaatggat
gtagctcctgcaggagcctgtggtgttatgctggcattgccagcaggaacagcagcaagc
gccagagctgtcctcttcaccgtggggtctcctccacacagtgccacagcccccacttgt
actcatatggtccttcgaacaagaaccacctcagtggggtccagcagctcaggaggttcc
ttgtgttctgcaagtggccgagtatgtgtgggctcccctcctggaccagggttgggctct
tccccaccaggagcagagggagctcccagcctaagatacgtgccttatggtgcttcacca
cccagcctagagggtctcatcacctttgaagcccctgaactaccagaggagacactgatg
gagcgagagcacacagacaccttacgccatctgaacatgatgttaatgtttactgagtgt
gtgctggacctgacggcagtgaggggtgggaaccctgagctgtgcacatctgctgtgtcc
ttgtaccagattcaggagagtgtagttgtggaccagatcagccagctaagcaaagattgg
gggcgggtggagcagctggtgttgtacatgaaggcagcacagctgctggcggcttccctg
catctcgccaaagctcaggtcaagtctgggaagctgagcccatccatggctgtgaaacaa
gttgttaaaaatctgaatgaaagatacaaattctgcatcaccatgtgcaagaaacttaca
gaaaagctgaatcgcttcttctccgataaacagagatttattgatgaaatcaacagtgtg
actgcagagaaactcatctataattgtgctgtggaaatggttcaatctgcagccctggat
gagatgtttcagcagactgaagacatcgtttatcgctaccacaaggcagcccttcttttg
gaaggcttaagtaagatcctgcaggaccctacagatgttgaaaatgtgcataagtataaa
tgtagtattgaaagaagattgtcagcactctgctgtagcactgcaactgtgtga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (11)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (50)   
   RefSeq(nuc) (8)   
   GenBank (21)   
   EMBL (21)   
Protein domain (10)   
   Pfam (10)   
All databases (107)   

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