KEGG   Mus musculus (house mouse): 329502
Entry
329502            CDS       T01002                                 
Symbol
Pla2g4e, 2310026J01Rik, C230096D22, Pla2epsilon
Name
(RefSeq) phospholipase A2, group IVE
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00564  Glycerophospholipid metabolism
mmu00565  Ether lipid metabolism
mmu00590  Arachidonic acid metabolism
mmu00591  Linoleic acid metabolism
mmu00592  alpha-Linolenic acid metabolism
mmu01100  Metabolic pathways
mmu04010  MAPK signaling pathway
mmu04014  Ras signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04217  Necroptosis
mmu04270  Vascular smooth muscle contraction
mmu04370  VEGF signaling pathway
mmu04611  Platelet activation
mmu04664  Fc epsilon RI signaling pathway
mmu04666  Fc gamma R-mediated phagocytosis
mmu04724  Glutamatergic synapse
mmu04726  Serotonergic synapse
mmu04730  Long-term depression
mmu04750  Inflammatory mediator regulation of TRP channels
mmu04912  GnRH signaling pathway
mmu04913  Ovarian steroidogenesis
mmu04921  Oxytocin signaling pathway
mmu05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    329502 (Pla2g4e)
   00565 Ether lipid metabolism
    329502 (Pla2g4e)
   00590 Arachidonic acid metabolism
    329502 (Pla2g4e)
   00591 Linoleic acid metabolism
    329502 (Pla2g4e)
   00592 alpha-Linolenic acid metabolism
    329502 (Pla2g4e)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    329502 (Pla2g4e)
   04014 Ras signaling pathway
    329502 (Pla2g4e)
   04370 VEGF signaling pathway
    329502 (Pla2g4e)
   04072 Phospholipase D signaling pathway
    329502 (Pla2g4e)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    329502 (Pla2g4e)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    329502 (Pla2g4e)
   04664 Fc epsilon RI signaling pathway
    329502 (Pla2g4e)
   04666 Fc gamma R-mediated phagocytosis
    329502 (Pla2g4e)
  09152 Endocrine system
   04912 GnRH signaling pathway
    329502 (Pla2g4e)
   04913 Ovarian steroidogenesis
    329502 (Pla2g4e)
   04921 Oxytocin signaling pathway
    329502 (Pla2g4e)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    329502 (Pla2g4e)
  09156 Nervous system
   04724 Glutamatergic synapse
    329502 (Pla2g4e)
   04726 Serotonergic synapse
    329502 (Pla2g4e)
   04730 Long-term depression
    329502 (Pla2g4e)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    329502 (Pla2g4e)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    329502 (Pla2g4e)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     329502 (Pla2g4e)
SSDB
Motif
Pfam: cPLA2_C2 PLA2_B C2
Other DBs
NCBI-GeneID: 329502
NCBI-ProteinID: NP_808513
MGI: 1919144
Ensembl: ENSMUSG00000050211
UniProt: Q50L42
Position
2:complement(119996893..120075816)
AA seq 875 aa
MQSIPHSDEADVAGMTHASEGHHGLGTSMLVPKNPQGEEDSKLGRNCSGFEDAQDPQTAV
PSSPLLSMASCSSQEGSSPCHLLTVRIIGMKNVRQADILSQTDCFVTLWLPTASQKKLKT
RTISNCLHPEWDESFTFQIQTQVKNVLELSVCDEDTLTQNDHLLTVLYDLSKLCLRNKTH
VKFPLNPEGMEELEVEFLLEENFSSSETLITNGVLVSRQVSCLEVHAESRRPRKRKKNKD
LLVMVTDSFENTQRVPPCQEPCYPNSACFHYPKYSQPQLYAEAPKSHCNFRLCCCGTHRN
DPVCQPLNCLSDGQVTTLPVGENYELHMKSSPCSDTLDVRLGFSLCQEEVEFVQKRKMVV
AKTLSQMLQLEEGLHEDEVPIIAIMATGGGTRSMVSLYGHLLGLQKLNFLDASTYITGLS
GATWTMATLYSDPEWSSKNLETVVFEARRHVVKDKMPALFPDQLYKWREDLQKHSQEGYK
TTFTDFWGKLIEYSLGDKKNECKLSDQRAALCRGQNPLPIYLTINVKDDVSNQDFREWFE
FSPYEVGMQKYGAFIPSELFGSEFFMGRLMKRIPEPEMCYMLGLWSSIFSLNLLDAWNLS
HTSEEFFYRWTRERLHDIEDDPILPEIPRCDDNPLETTVVIPTTWLSNTFREILTRRPFV
SEFHNFLYGMQLHTDYLQNRQFSMWKDTVLDTFPNQLTQFAKHLNLLDTAFFVNSSYAPL
LRPERKVDLIIHLNYCAGSQTKPLKQTCEYCTEQKIPFPSFSILEDDNSLKECYVMENPQ
EPDAPIVAYFPLISDTFQKYKAPGVERSPDELELGQLNIYGPKSPYATKELTYTEAAFDK
LVKLSEYNILNNRDKLIQALRLAMEKKRMRSQCPS
NT seq 2628 nt   +upstreamnt  +downstreamnt
atgcagtctattccacactccgatgaagcagacgtggctgggatgacccacgcctcagaa
ggccaccatggcctggggaccagcatgcttgtcccaaagaacccacaaggggaagaagac
agcaagctaggaagaaactgcagtggatttgaagatgcacaggacccacagactgctgtg
ccctcctcacctttactttccatggcttcttgcagttctcaggaggggtcatctccatgc
catctgttgacagtgaggatcattggcatgaaaaacgtccggcaggctgatatactgagt
cagacagactgctttgtgaccctctggctgcctactgcctctcagaagaagctgaagacc
agaaccatctccaactgcctacacccagagtgggacgaaagcttcacctttcagatccag
actcaagtaaagaatgtgctagagctgagcgtctgtgacgaagacaccctgacacaaaat
gaccatctcttgacagtcctctatgacctctctaagctttgcctccggaataaaacccat
gtgaagttcccactcaacccagagggcatggaagaactggaggtggagttcctactcgaa
gagaatttctcctcatcagagaccctcatcaccaacggcgtgctggtgtctcgccaagtc
tcttgcctggaggttcatgcagaatccaggaggccgaggaagaggaagaaaaacaaagac
cttctggtgatggtgacagactccttcgagaacacccagcgtgtcccgccttgccaggag
ccctgctaccccaattctgcctgcttccactaccccaagtactcccagccacagctttac
gcagaggcgcctaagagccactgtaactttaggctttgctgctgcggaacacacaggaat
gaccctgtctgccagcccctcaattgcctttctgatggccaggtgacaaccctgcctgtg
ggagagaactatgagctacacatgaagtcctcaccctgctctgacacactggatgtgcgg
cttggattcagcctgtgccaggaagaggtggagtttgtgcagaagcggaagatggtggtg
gccaagacactaagtcagatgctgcagctggaggaaggcctgcatgaggatgaggtaccg
ataatagccatcatggccacaggaggtggcacaaggtctatggtctccttgtatggccac
ctgctggggttgcagaagctgaactttctggacgcttctacttacatcaccggcttgtca
ggtgcaacctggactatggctaccttgtacagtgatcctgagtggtcctccaaaaacctg
gagactgttgtctttgaggcccggagacatgttgtcaaagacaagatgcctgccctgttc
ccagatcagctctacaaatggcgagaggacctccaaaagcatagccaggagggctataag
accacgtttacagacttttggggcaagctgatcgagtacagtctgggagataaaaaaaac
gaatgcaagctgtcagatcagcgagctgctctgtgcaggggacagaaccctctgcccatc
tacctcaccatcaatgtcaaggatgatgtaagcaaccaggatttcagagaatggttcgag
ttctccccctacgaggtgggcatgcagaagtacggagccttcatccccagcgagttattt
ggctccgagttcttcatggggcggctgatgaagaggattcctgagccggagatgtgctac
atgctagggttgtggagtagcatcttttccctgaacctgcttgatgcctggaatttgtct
cacacctcagaggagtttttctataggtggacaagggagagactgcatgacatcgaagat
gatcccatcctgcctgaaatccctaggtgtgacgataaccccctagagaccacagtagtg
atcccaacgacatggctgtccaacaccttccgagaaatcctcacacgcaggcccttcgtg
tctgagttccacaacttcctgtacgggatgcagctgcatactgactacttacagaacagg
cagttctctatgtggaaagacacagtactggacaccttcccaaaccagctgacacagttt
gcaaaacacctgaacctgctggacactgcgttctttgtcaactccagctacgcacccctc
cttaggccagagagaaaagtcgaccttatcatccacctcaattactgcgcaggatcccag
acaaagcccctgaaacaaacctgtgagtactgtaccgagcagaagatccccttccccagc
ttctccatcctggaagatgacaacagtctcaaggagtgctacgtgatggagaatccccag
gagcccgacgcccccatcgtggcttacttcccactcatcagtgacaccttccagaagtac
aaggctccaggtgtagagcgaagtcctgacgagctggaactgggccagctgaacatctat
ggaccaaagtctccctatgccaccaaggagctgacgtacacagaggccgccttcgacaag
ctggtgaagctctcagaatataatatcctcaataacagagataagctcattcaggccttg
agactagcaatggagaagaaacgcatgaggagccagtgtccctcctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (23)   
   KEGG PATHWAY (23)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (19)   
   RefSeq(nuc) (5)   
   GenBank (7)   
   EMBL (7)   
Protein domain (3)   
   Pfam (3)   
All databases (107)   

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