KEGG   Mus musculus (house mouse): 50721
Entry
50721             CDS       T01002                                 
Symbol
Sirt6, 2810449N18Rik, Sir2l6, mSIRT6
Name
(RefSeq) sirtuin 6
  KO
K11416  NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00760  Nicotinate and nicotinamide metabolism
mmu01100  Metabolic pathways
mmu04714  Thermogenesis
mmu05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    50721 (Sirt6)
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    50721 (Sirt6)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    50721 (Sirt6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    50721 (Sirt6)
Enzymes [BR:mmu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.286  protein acetyllysine N-acetyltransferase
     50721 (Sirt6)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    SIRTs (sirtuins, class III HDACs)
     50721 (Sirt6)
SSDB
Motif
Pfam: SIR2 TPP_enzyme_M
Other DBs
NCBI-GeneID: 50721
NCBI-ProteinID: NP_853617
MGI: 1354161
Ensembl: ENSMUSG00000034748
UniProt: P59941
Position
10:complement(81457621..81463631)
AA seq 334 aa
MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLMWQSSSVVFHTGAGISTASG
IPDFRGPHGVWTMEERGLAPKFDTTFENARPSKTHMALVQLERMGFLSFLVSQNVDGLHV
RSGFPRDKLAELHGNMFVEECPKCKTQYVRDTVVGTMGLKATGRLCTVAKTRGLRACRGE
LRDTILDWEDSLPDRDLMLADEASRTADLSVTLGTSLQIRPSGNLPLATKRRGGRLVIVN
LQPTKHDRQADLRIHGYVDEVMCRLMKHLGLEIPAWDGPCVLDKALPPLPRPVALKAEPP
VHLNGAVHVSYKSKPNSPILHRPPKRVKTEAAPS
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtcggtgaattatgcagcagggttgtcgccttacgcggataagggcaagtgcgggctg
cccgagatcttcgacccaccagaggagctggaacgcaaggtgtgggagctggcccggcta
atgtggcagtcctccagcgtggttttccacacgggcgccggcatcagcaccgcctctggc
atccccgacttcagaggcccccatggcgtgtggaccatggaggaacgcggcctggccccc
aagtttgacaccaccttcgagaatgctcggccctcgaagacccacatggccctggttcag
ctagaacgcatgggcttcctcagcttcctggtcagccagaacgtagacgggctgcacgtg
cgctcgggcttccccagggacaagctggcagagctgcacggaaacatgtttgtagaggaa
tgtcccaagtgtaagacgcagtacgtcagagacacggttgtgggcaccatgggcctcaag
gccacaggccggctctgcaccgtggccaagaccaggggacttcgggcctgtagaggggag
ctgagagacaccattctggactgggaggactcgttgcctgaccgggacctgatgctcgct
gatgaggccagcaggaccgcagacctgtctgtcaccctgggtacctcgctgcagatccgc
cccagtgggaacctgccccttgccactaagcgccgaggaggccgtctggtcattgtcaac
ctgcaacccacaaaacatgaccgccaggctgacctgcgcatccacggctacgtggatgag
gtgatgtgcagactcatgaagcatctggggctggagattccagcctgggatggaccctgc
gtgctagacaaagccctgccacctctgcctcgcccagtagcactcaaggctgagcccccc
gtgcatctcaatggtgcagtgcatgtttcgtataagtccaagcccaacagccctatactc
cacaggccccccaaaagagtgaagaccgaggctgcccccagctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (18)   
   RefSeq(nuc) (6)   
   GenBank (6)   
   EMBL (6)   
Protein domain (2)   
   Pfam (2)   
All databases (58)   

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