KEGG   Mus musculus (house mouse): 53313
Entry
53313             CDS       T01002                                 
Symbol
Atp2a3, SERCA3b, Serca3
Name
(RefSeq) ATPase, Ca++ transporting, ubiquitous
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04020  Calcium signaling pathway
mmu04022  cGMP-PKG signaling pathway
mmu04024  cAMP signaling pathway
mmu04148  Efferocytosis
mmu04260  Cardiac muscle contraction
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04380  Osteoclast differentiation
mmu04919  Thyroid hormone signaling pathway
mmu04972  Pancreatic secretion
mmu05010  Alzheimer disease
mmu05017  Spinocerebellar ataxia
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05410  Hypertrophic cardiomyopathy
mmu05412  Arrhythmogenic right ventricular cardiomyopathy
mmu05414  Dilated cardiomyopathy
mmu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    53313 (Atp2a3)
   04024 cAMP signaling pathway
    53313 (Atp2a3)
   04022 cGMP-PKG signaling pathway
    53313 (Atp2a3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    53313 (Atp2a3)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    53313 (Atp2a3)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    53313 (Atp2a3)
   04261 Adrenergic signaling in cardiomyocytes
    53313 (Atp2a3)
  09154 Digestive system
   04972 Pancreatic secretion
    53313 (Atp2a3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    53313 (Atp2a3)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    53313 (Atp2a3)
   05017 Spinocerebellar ataxia
    53313 (Atp2a3)
   05022 Pathways of neurodegeneration - multiple diseases
    53313 (Atp2a3)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    53313 (Atp2a3)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    53313 (Atp2a3)
   05414 Dilated cardiomyopathy
    53313 (Atp2a3)
   05415 Diabetic cardiomyopathy
    53313 (Atp2a3)
Enzymes [BR:mmu01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     53313 (Atp2a3)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD DUF3106
Other DBs
NCBI-GeneID: 53313
NCBI-ProteinID: NP_001156808
MGI: 1194503
Ensembl: ENSMUSG00000020788
UniProt: Q64518 Q8R0X5 Q8C213 Q3U1K2 Q3U6T4
Position
11:72851995..72883869
AA seq 999 aa
MEEAHLLSAADVLRRFSVTAEGGLSLEQVTDARERYGPNELPTEEGKSLWELVVEQFEDL
LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK
EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL
TGESVSVTKHTDAIPDPRAVNQDKKNMLFSGTNIASGKALGVAVATGLQTELGKIRSQMA
AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFVVAEAEAGTCRLHEFTISGTTYTPEGEVRQGEQPVRCGQFDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRVERAGACNSVIKQLMR
KEFTLEFSRDRKSMSVYCTPTRADPKVQGSKMFVKGAPESVIERCSSVRVGSRTAPLSTT
SREHILAKIRDWGSGSDTLRCLALATRDTPPRKEDMHLDDCSRFVQYETDLTFVGCVGML
DPPRPEVAACITRCSRAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVLGKAYTGREFDD
LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAI
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRNPREALISGWLFFRYLAI
GVYVGLATVAAATWWFLYDTEGPQVTFYQLRNFLKCSEDNPLFAGIDCKVFESRFPTTMA
LSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLGAVVMSMALHFLILLVPPLPLIFQVT
PLSGRQWGVVLQMSLPVILLDEALKYLSRNHMDEKKDLK
NT seq 3000 nt   +upstreamnt  +downstreamnt
atggaggaggcgcacctgctctccgctgccgacgtgctgcgtcgcttctcggtgacagcc
gagggcggcttgagcctggagcaggtgaccgacgcgcgggagcgttacggccccaacgag
ctcccgaccgaggaagggaaatccctgtgggagctggtggtggagcagtttgaggacctc
ttggtgcgcatcctgctgctggcagctctggtttcctttgtcctggcctggttcgaggag
ggtgaggagaccacaacggccttcgtggagcccctggtcatcatgctaattctcgtggcc
aatgcgatcgtgggagtgtggcaggaacgcaacgcagagagtgcaattgaggccttgaag
gagtatgagcctgagatgggtaaggtgatccggtctgaccgcaagggtgtacagaggatc
cgagccagggacatcgtccctggggacattgtggaagtggcagtgggagacaaggtaccc
gctgacctccgtctcatcgagatcaagtccaccacacttcgagtggaccagtccatcctg
acaggggaatccgtgtctgtgacgaagcacacagatgccattccagacccccgagccgtg
aaccaggacaagaagaacatgctattttctggcaccaatattgcatcaggcaaagccctg
ggtgtggctgtggctacaggcctgcagacagagctgggcaagattcggagccagatggcg
gctgtggagcctgagcggacgccattgcagcgcaagctggatgaatttgggaggcagctg
tcccatgccatctctgtgatctgtgtggctgtgtgggtcatcaacatcggccactttgct
gacccggcccacggtggatcctggctccgtggtgcagtctactacttcaagatcgctgtg
gccctggctgtggctgctatccccgagggtctcccagcagtcatcactacatgcctggcc
ctgggcacaagacgtatggcacgtaagaatgccattgtgcggagcctgccttctgtggag
acgctgggctgcacctcggtcatctgctctgacaagacggggacgctcaccaccaatcag
atgtctgtctgcaggatgttcgtggtggctgaagcagaggcaggcacctgtcgtttgcat
gaattcaccatttcgggtaccacgtacaccccagagggcgaagtgaggcaaggggagcag
cctgtgcgctgtgggcagtttgatgggctagtggagctcgccaccatctgtgccctctgc
aatgattctgcgctggactacaatgaggccaagggtgtgtatgagaaggtaggagaggcc
acagagaccgccctgacttgcctggtagagaagatgaatgtgtttgacacagacctgaaa
ggactgtcgcgggtggagcgtgctggcgcctgcaactcagtcatcaagcaactcatgcgg
aaagagttcaccctggagttctcccgggaccggaagtctatgtccgtgtactgcacacct
actcgtgctgaccccaaggtccagggcagcaagatgtttgtgaagggagctcctgagagt
gtaattgagcgctgtagctcagtccgagtgggcagccgaacagcacccctgagcaccact
tccagagagcatatcctggccaagatccgggactggggctcaggctctgacacactgcgc
tgcttagccttggccaccagggacacacccccaaggaaggaggacatgcatctagatgac
tgcagccggtttgtacagtacgagacagacctgaccttcgtgggctgcgtgggcatgtta
gacccaccgagaccagaggtggctgcttgtatcacacgctgttcccgggctggcattcga
gtggtcatgatcacaggggacaacaaagggacagctgtggccatctgccgccgacttggc
atctttggggacacggaggatgtgttgggcaaggcctacacgggccgtgagtttgatgac
ctcagcccagagcagcagcgccaggcttgtcgcactgcccggtgctttgcccgagtggaa
cccgcacataagtctcgaatcgtggagaacctacagtcctttaatgagatcactgccatg
actggcgatggggtgaatgatgcaccagccctgaagaaggcagagatcggcatcgccatg
ggctcaggcactgctgtggccaagtcagcagcagagatggtgctgtccgatgacaacttt
gcctccattgtggctgcagtagaagagggcagggccatctacaacaacatgaagcagttc
atccgctacctcatctcctccaatgttggcgaggttgtctgcatcttcctcacagcaatt
ctgggcctgcccgaagctctgatccctgtgcagctgctctgggtgaacctggtaacagat
ggcttaccggccacagcccttggcttcaacccaccagatctggatatcatggagaagccg
cctcggaatccccgtgaggccctcatcagtggctggctttttttccgctatttggctatt
ggagtgtatgtaggcctggctacagtggctgccgccacctggtggttcctgtatgacacc
gagggacctcaagtcaccttctatcagctgaggaacttcctgaagtgctctgaagacaat
ccactgtttgctggcattgactgcaaggtttttgagtcacgcttccccacaaccatggcc
ttatctgtgcttgtgaccattgaaatgtgcaacgccctcaacagcgtctctgagaaccag
tcactgctgcgcatgccaccctggctgaacccttggctgctgggggctgtggtcatgtcc
atggctctgcattttcttatcctcctggtgccacctctgcctctcatttttcaggtgacc
ccactgagtggtcggcagtggggggtggtgcttcagatgtctctgcctgtcatcctgctc
gatgaggccctcaagtatctgtccaggaatcacatggatgaaaaaaaggacctgaagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (5)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (21)   
   RefSeq(nuc) (3)   
   GenBank (9)   
   EMBL (9)   
Protein domain (8)   
   Pfam (8)   
All databases (71)   

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