KEGG   Mus musculus (house mouse): 53859
Entry
53859             CDS       T01002                                 
Symbol
Map3k14, Nik, aly
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 14
  KO
K04466  mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04064  NF-kappa B signaling pathway
mmu04210  Apoptosis
mmu04380  Osteoclast differentiation
mmu04625  C-type lectin receptor signaling pathway
mmu04660  T cell receptor signaling pathway
mmu04668  TNF signaling pathway
mmu04672  Intestinal immune network for IgA production
mmu04936  Alcoholic liver disease
mmu05166  Human T-cell leukemia virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    53859 (Map3k14)
   04064 NF-kappa B signaling pathway
    53859 (Map3k14)
   04668 TNF signaling pathway
    53859 (Map3k14)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    53859 (Map3k14)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    53859 (Map3k14)
   04660 T cell receptor signaling pathway
    53859 (Map3k14)
   04672 Intestinal immune network for IgA production
    53859 (Map3k14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    53859 (Map3k14)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    53859 (Map3k14)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    53859 (Map3k14)
   05169 Epstein-Barr virus infection
    53859 (Map3k14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    53859 (Map3k14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    53859 (Map3k14)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     53859 (Map3k14)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: STE group
  Other
   53859 (Map3k14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal APH TCAD9
Other DBs
NCBI-GeneID: 53859
NCBI-ProteinID: NP_058592
MGI: 1858204
Ensembl: ENSMUSG00000020941
UniProt: Q9WUL6 Q544K4
Structure
Position
11:complement(103110590..103158227)
AA seq 942 aa
MAVMEVACPGTPGSAVGQQKELAKAKEKTQSLGKKQSCIFKLEAVEKSPVFCGKWEILND
VITKGTAKDGSEGGPPAISIIAQAECENSQEFSPTFSERIFIAGSQQYSQSESLDQIPNN
VAHATEGKMARVCRRGKRHGKARKKRRKKRSKSLAQAGVALAKPLPRTPEQESCTIPVQE
DESPLGNLYARNVSQFTKPLGGPGLGHLCFKKQDEGLRPVLPRPELHKLISPLQCLNHVW
KLHHPQATGPRPHPTHPFPYSGMPHPFPFYPLEPWKPYMLDSAVLDKLAGVSGQRPLPGP
PHLSQLAHGDSQKPLPGPHLESSCPSRGALEKVPVEEYLVHALQGSVSSGQAHSLASLAK
TWSSGSAKLQRLGPETEDNEGVLLTEKLKPVDYEYREEVHWMTHQPRVGRGSFGEVHRMK
DKQTGFQCAVKKVRLEVFRVEELVACAGLSSPRIVPLYGAVREGPWVNIFMELLEGGSLG
QLIKQMGCLPEDRALYYLGQALEGLEYLHTRRILHGDVKADNVLLSSDGSRAALCDFGHA
LCLQPDGLGKSLLTGDYIPGTETHMAPEVVMGKPCDAKVDIWSSCCMMLHMLNGCHPWTQ
YFRGPLCLKIASEPPPIREIPPSCAPLTAQAIQEGLRKEPVHRASAMELRRKVGKALQEV
GGLKSPWKGEYKEPRPPPQDQATCHQTLPTPPRENPPAKANTDGAPEPQPPLPPEPPEPS
KAPALNLSKEESGTWEPLPLSSLDPATAKGPSFPDRRATLPELELQQLEIELFLNSLSQP
FSLEEQEQILSCLSIDSLSLSDDSEKNPSKASQSSRDTLSSGVHSWNSQAEARTCSCSTA
LARGRPTDIPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPATAFSLVTKD
GQPVCYDMEVPDSGIDLQCTLAPDGSFAWTWRVKHGQLENRP
NT seq 2829 nt   +upstreamnt  +downstreamnt
atggccgtgatggaagtggcctgcccgggcactcctgggtcagcagtcgggcagcagaag
gagcttgccaaagccaaggagaagacacagtcactggggaagaagcagagctgcatcttc
aagcttgaggccgtggagaagagccccgtgttctgtgggaagtgggagatcctaaacgac
gtgatcaccaaaggcacagccaaggacggctctgagggaggaccaccggccatctccatc
atcgcccaggctgaatgtgagaatagccaagagttcagccccaccttctcagagcgcatt
ttcatcgcggggtcacagcagtacagccagtctgagagtctcgatcaaatccccaacaat
gtggcccatgcaactgaaggcaaaatggcccgtgtgtgccggaggggaaaacgtcacggc
aaagcccgaaaaaaacgtaggaagaagaggtcgaagtcactggcccaggcaggagtggcc
ttagccaagcccctgcccagaacccctgagcaagagagctgtaccatcccagtacaggaa
gatgagtctccactaggcaacctctatgccagaaatgtctcccagttcaccaagcctctg
gggggaccaggccttggccacctgtgctttaagaaacaagatgaaggcctgcgaccggta
ctgcctcgaccagaactccacaaactgatcagccccttgcaatgtctaaaccacgtgtgg
aaactccaccacccccaggccacaggcccccggccccacccgactcaccccttcccctac
agcggaatgccccatcctttcccattctaccccctggagccctggaaaccctatatgctg
gactctgccgtcctggacaaactagccggtgtcagcggccagcggcctctgcctggccca
ccgcatctaagccaactggcccatggagacagtcagaagccgctgcctggcccacacctg
gagtccagctgcccgtctcggggtgccctagaaaaggttcccgtggaggaatacctggtg
catgcgctccaaggaagtgtgagctcaggccaggcccacagcctggccagcctggctaag
acatggtcctcgggaagcgccaagctgcagaggctcggccccgaaactgaggacaacgag
ggggtcctgcttactgagaaactcaagccagtggattatgagtatcgagaagaggtccac
tggatgacacaccagcctcgggtgggcagaggctccttcggcgaggtccacagaatgaag
gacaagcagacaggcttccagtgtgctgtcaaaaaggtacgactcgaggtgtttcgggta
gaggaactagtggcctgtgctggtctgagctcgcccagaatcgtccctctctatggagct
gtgagagaaggcccgtgggtgaacatcttcatggaactgctagaaggtggctcgctgggt
cagctcataaagcaaatgggctgtctgccagaagaccgagccctttactacctgggccag
gccctggaggggctggagtacctccacacacgcaggattctgcatggcgatgtcaaagct
gacaacgtgctcctgtccagtgatggaagccgagcggccctctgcgactttggccacgcc
ttgtgcctgcaacctgacggcctagggaaatccttgctcacaggggactacattcctggc
acggagacccacatggcaccagaagtggtgatgggaaagccctgcgatgccaaggtggac
atctggagcagctgctgcatgatgctccacatgctcaacggctgccacccctggactcag
tacttccgaggcccgctttgtctcaagattgccagcgagcctccaccgatcagggagatc
ccaccttcctgcgcacccctcacagcccaggccatccaagaggggctgaggaaagagccc
gtccaccgagcatctgccatggagcttcggaggaaagtgggcaaggcactacaggaagtg
ggaggtctgaaaagcccttggaaaggagaatataaagaaccaagacctccaccccaagac
caagccacctgccaccagaccctacctactccgccgagagagaacccaccagccaaggcc
aacacagacggggctcctgagcctcagcctcctctaccgccagaaccaccagaaccgagc
aaagcgccagccctgaacctgagcaaggaggagtctggcacatgggaacccctgcctctg
tcctccctggacccagccactgccaaaggccccagcttcccagaccggagggcaaccttg
ccagagctggagctacagcaactggagatagaactgtttctcaacagcctgtcccagccg
ttctctctggaggaacaggaacaaatcctctcctgcctcagcatcgacagcctctcgctg
tcagatgacagtgaaaagaatccatcgaaggcctctcagagctcacgggacaccctgagt
tctggcgtgcactcttggaacagccaagctgaggcaagaacctgcagctgcagcacggcg
ctggcccgggggcggcctactgacatcccgagctacttcaacggggtcaaggtccagatc
cagtctctcaatggcgaacacctgcatatccgggaattccaccgcgtcaaggtgggagac
attgccaccggcatcagcagccagatcccagccacagctttcagcctggtgaccaaagat
ggacagcctgtttgctatgacatggaggtgccagactcgggcatcgacctgcagtgcacc
ctggcccctgatggcagctttgcttggacctggagggtcaagcatggtcagctggagaac
cgaccctag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
3D Structure (11)   
   PDB (11)   
Protein domain (5)   
   Pfam (5)   
All databases (79)   

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