KEGG   Mus musculus (house mouse): 54131
Entry
54131             CDS       T01002                                 
Symbol
Irf3, C920001K05Rik, IRF-3
Name
(RefSeq) interferon regulatory factor 3
  KO
K05411  interferon regulatory factor 3
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04620  Toll-like receptor signaling pathway
mmu04621  NOD-like receptor signaling pathway
mmu04622  RIG-I-like receptor signaling pathway
mmu04623  Cytosolic DNA-sensing pathway
mmu04936  Alcoholic liver disease
mmu05133  Pertussis
mmu05135  Yersinia infection
mmu05160  Hepatitis C
mmu05161  Hepatitis B
mmu05162  Measles
mmu05163  Human cytomegalovirus infection
mmu05164  Influenza A
mmu05165  Human papillomavirus infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05171  Coronavirus disease - COVID-19
mmu05203  Viral carcinogenesis
mmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    54131 (Irf3)
   04621 NOD-like receptor signaling pathway
    54131 (Irf3)
   04622 RIG-I-like receptor signaling pathway
    54131 (Irf3)
   04623 Cytosolic DNA-sensing pathway
    54131 (Irf3)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    54131 (Irf3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    54131 (Irf3)
   05161 Hepatitis B
    54131 (Irf3)
   05160 Hepatitis C
    54131 (Irf3)
   05171 Coronavirus disease - COVID-19
    54131 (Irf3)
   05164 Influenza A
    54131 (Irf3)
   05162 Measles
    54131 (Irf3)
   05168 Herpes simplex virus 1 infection
    54131 (Irf3)
   05163 Human cytomegalovirus infection
    54131 (Irf3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    54131 (Irf3)
   05169 Epstein-Barr virus infection
    54131 (Irf3)
   05165 Human papillomavirus infection
    54131 (Irf3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    54131 (Irf3)
   05133 Pertussis
    54131 (Irf3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    54131 (Irf3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    54131 (Irf3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    54131 (Irf3)
   04131 Membrane trafficking [BR:mmu04131]
    54131 (Irf3)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters interferon-regulating factors
    54131 (Irf3)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Other autophagy associated proteins
   TRIM-directed selective autophagy
    54131 (Irf3)
SSDB
Motif
Pfam: IRF-3 IRF
Other DBs
NCBI-GeneID: 54131
NCBI-ProteinID: NP_058545
MGI: 1859179
Ensembl: ENSMUSG00000003184
UniProt: P70671 Q3U9K6
Structure
Position
7:44647072..44652272
AA seq 419 aa
METPKPRILPWLVSQLDLGQLEGVAWLDESRTRFRIPWKHGLRQDAQMADFGIFQAWAEA
SGAYTPGKDKPDVSTWKRNFRSALNRKEVLRLAADNSKDPYDPHKVYEFVTPGARDFVHL
GASPDTNGKSSLPHSQENLPKLFDGLILGPLKDEGSSDLAIVSDPSQQLPSPNVNNFLNP
APQENPLKQLLAEEQWEFEVTAFYRGRQVFQQTLFCPGGLRLVGSTADMTLPWQPVTLPD
PEGFLTDKLVKEYVGQVLKGLGNGLALWQAGQCLWAQRLGHSHAFWALGEELLPDSGRGP
DGEVHKDKDGAVFDLRPFVADLIAFMEGSGHSPRYTLWFCMGEMWPQDQPWVKRLVMVKV
VPTCLKELLEMAREGGASSLKTVDLHISNSQPISLTSDQYKAYLQDLVEDMDFQATGNI
NT seq 1260 nt   +upstreamnt  +downstreamnt
atggaaaccccgaaaccgcggattttgccctggctggtgtcacagctggacctggggcag
ctggaaggcgtggcctggctggacgagagccgaacgaggttcaggatcccgtggaagcat
ggcctacggcaggacgcacagatggctgactttggcatcttccaggcctgggcagaagcc
agtggtgcctacaccccggggaaggataagccggacgtgtcaacctggaagaggaatttc
cggtcagccctgaaccggaaagaagtgttgcggttagctgctgacaatagcaaggaccct
tatgaccctcataaagtgtatgagtttgtgactccaggggcgcgggacttcgtacatctg
ggtgcctctcctgacaccaatggcaaaagcagcctgcctcactcccaggaaaacctaccg
aagttatttgatggcctgatcttggggcccctcaaagatgaggggtcctcagatctggct
attgtttctgatccttctcaacaactgccaagccccaatgtgaacaacttcctaaaccct
gcaccccaagaaaatccactgaagcagctgctagctgaggaacaatgggagttcgaggtg
accgccttctaccgaggccgccaggtcttccagcagacactcttttgcccggggggcctg
cggctggtgggcagcacagctgacatgacactgccctggcagccagtcaccctgcccgat
cctgaggggtttctgacggacaagcttgtgaaggagtacgtggggcaggtgctcaaaggg
ctgggcaatgggctggcactgtggcaggctgggcagtgcctctgggcccagcgcctaggc
cactcccacgccttctgggctctgggggaggagctgcttccagacagtgggcgagggcct
gatggagaggtccacaaggacaaggacggagccgtgttcgacctcaggcccttcgtggca
gatctgattgccttcatggaaggaagtggacactccccacgctacactctgtggttctgc
atgggggaaatgtggccccaggaccagccatgggtcaagaggcttgtgatggtcaaggtt
gttcctacatgtcttaaggagctgttagagatggcccgggaagggggagcctcttcactg
aaaaccgtggacttgcacatctccaacagccagcctatctcccttacctctgaccagtac
aaggcctacctccaggacttggtggaggacatggacttccaggccactggaaatatctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (20)   
   KEGG PATHWAY (20)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (30)   
   RefSeq(nuc) (4)   
   GenBank (13)   
   EMBL (13)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (78)   

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