KEGG   Mus musculus (house mouse): 545291
Entry
545291            CDS       T01002                                 
Symbol
Hpse2, Gm968, Hpa2
Name
(RefSeq) heparanase 2
  KO
K07965  heparanase 2 [EC:3.2.1.-]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00531  Glycosaminoglycan degradation
mmu01100  Metabolic pathways
mmu05205  Proteoglycans in cancer
Module
mmu_M00078  Heparan sulfate degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    545291 (Hpse2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    545291 (Hpse2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:mmu00536]
    545291 (Hpse2)
Glycosaminoglycan binding proteins [BR:mmu00536]
 Heparan sulfate / Heparin
  Enzymes
   545291 (Hpse2)
SSDB
Motif
Pfam: Glyco_hydro_79n
Other DBs
NCBI-GeneID: 545291
NCBI-ProteinID: NP_001074726
MGI: 2685814
Ensembl: ENSMUSG00000074852
UniProt: B2RY83
Position
19:complement(42774980..43376913)
AA seq 592 aa
MRVLCAFPEAMASSSSRPPSCLALVALFLALLLHLSLSFHAGNRRPLPVDRATGLKEKTL
ILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRT
DFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREK
ASQMHLVLLKEQYSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSS
ALSLLKYSASKKYNISWELGNEPNNYRSIHGRAVNGSQLGKDYIQLKSLLQPIRVYSRAS
LYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQ
IRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIR
HSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRI
YAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSV
QLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR
NT seq 1779 nt   +upstreamnt  +downstreamnt
atgagggtgctctgtgctttccctgaagccatggcctccagcagctcccgccccccctcg
tgcctagccctggtggctctcttcttggctctgttgctccatctctccctctccttccac
gctggaaacaggagacctttgcctgtagacagagctacaggtttgaaggaaaagaccctg
attctacttgatgtgagcaccaagaacccagtcaggacagtcaatgagaacttcctctct
ctgcagctggatccctccatcattcatgatggctggctcgatttcttaagctccaagcgt
ctggtgaccttggcccggggactctcgcccgcctttctgcgcttcgggggcaaaaggacg
gatttcctgcagttccagaacctgagaaatccggcgaaaagccgcgggggcccgggcccg
gattactatctcaaaaactatgaggatgacattgtccggagtgatgttgccttggacaag
cagaaaggctgtaagattgcccagcaccctgatgtcatgctggagctccagagagagaag
gcatcgcagatgcatctggttcttctgaaggagcaatactccaatacttacagtaacctc
atattaacagccaggtctctagacaaactttataactttgctgattgctctggactccac
ctgatatttgctctaaatgcactgcgtcgtaatcccaataactcctggaacagttctagt
gccctgagcctgttgaagtacagtgccagcaaaaagtacaacatttcttgggaactgggt
aatgagccaaataactatcggagcatccatggccgggcagtaaatggtagccagttggga
aaggattacatccagctgaagagcctgctccaacccatccgggtttactccagagccagc
ctgtacggccccaacatcggacggcccaggaagaacgtcattgctctcctagatggattc
atgaaggtggcaggaagcacagtggatgcggttacctggcaacattgctacattgatggc
cgggtggtcaaggtgatggacttcctgaaaactcgtctgttagatacactctctgaccag
attaggaaaattcagaaagtggtcaacacatacactccaggaaagaagatttggctggaa
ggcgtggtgaccacctcagctggaggcacaaacaatctgtcggattcctacgctgcagga
ttcttatggctaaacactttaggaatgttggccaatcagggcattgatgtcgtgatacga
cattcatttttcgaccacggatacaaccatctggtggaccagaattttaacccattacca
gactattggctttctctgctttacaagcgtctgattggccccaaagtcctggcagtgcat
gtagctgggctccagcggaagcctcggccaggaagagtcatccgagacaaactaagaatc
tatgctcactgcacaaaccaccacaaccacaactatgtccgtggctctatcacacttttc
atcatcaacctacatcgatcaagaaagaaaatcaaactggctgggactctgagggacaag
ctcgtgcaccagtatctgctgcagccctatgggcaggaaggcctaaagtccaagtcagtg
cagctcaatggccagcccttagtgatggtggacgacgggacccttccagaactgaagccc
cgcccgctgcgggccggccggacattggtcatccctccagtcaccatgggcttttatgtg
gtcaagaatgtcaatgctttggcctgccgttatcgataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (14)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (5)   
Protein domain (1)   
   Pfam (1)   
All databases (40)   

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