KEGG   Mus musculus (house mouse): 56632
Entry
56632             CDS       T01002                                 
Symbol
Sphk2, Sk2, Spk2
Name
(RefSeq) sphingosine kinase 2
  KO
K04718  sphingosine kinase [EC:2.7.1.91]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00600  Sphingolipid metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04071  Sphingolipid signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04148  Efferocytosis
mmu04370  VEGF signaling pathway
mmu04371  Apelin signaling pathway
mmu04666  Fc gamma R-mediated phagocytosis
mmu05152  Tuberculosis
Module
mmu_M00100  Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    56632 (Sphk2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    56632 (Sphk2)
   04371 Apelin signaling pathway
    56632 (Sphk2)
   04020 Calcium signaling pathway
    56632 (Sphk2)
   04072 Phospholipase D signaling pathway
    56632 (Sphk2)
   04071 Sphingolipid signaling pathway
    56632 (Sphk2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    56632 (Sphk2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    56632 (Sphk2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    56632 (Sphk2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphingosine kinase
     56632 (Sphk2)
SSDB
Motif
Pfam: DAGK_cat YegS_C
Other DBs
NCBI-GeneID: 56632
NCBI-ProteinID: NP_001166032
MGI: 1861380
Ensembl: ENSMUSG00000057342
UniProt: Q9JIA7 Q58E38
Position
7:complement(45358887..45367426)
AA seq 617 aa
MAPPPLLPVAASTPILHGEFGSYPANGPRFALTLTTQALHIQRLRPKPEARPRDGLVSLD
EVSGCGTLQSRSPEDTAAYFCIYTYPRGRRGGRRRATRTFRADGATTYEENRAEAQRWAT
ALTCLLRGVPLSGDQEITPELLPRKPRLLILVNPFGGRGLAWQRCMDHVVPMISEAGLSF
NLIQTERQNHARELVQGLSLSEWEGIVTVSGDGLLYEVLNGLLDRPDWEDAVRMPIGVLP
CGSGNALAGAVNHHGGFEQVVGVDLLLNCSLLLCRGGSHPLDLLSVTLASGSRCFSFLSV
AWGFLSDVDIHSERFRALGSARFTLGAVLGLASLHTYRGRLSYLPATTEPALPIPGHSLP
RAKSELVLAPAPAPAATHSPLHRSVSDLPLPLPQPALVSPGSPEPLPDLSLNGGGPELTG
DWGGAGDAPLSPDPLLPSSPNALKTAQLSPIAEGPPEMPASSGFLPPTHSAPEASTWGPV
DHLLPPLGSPLPQDWVTIEGEFVLMLGILPSHLCADLMAAPHARFDDGVVHLCWVRSGIS
RAALLRILLAMEHGNHFSLGCPHLGYAAARAFRLEPLTPRGLLTVDGELVEYGPIQAQVH
PGLATLLTGPAGQKPQA
NT seq 1854 nt   +upstreamnt  +downstreamnt
atggccccaccaccactactgccagtggctgccagcactccaatcctgcacggcgagttt
ggttcctacccggccaacggcccacggtttgccctcaccctcacaacacaagccctacac
atacagcgactacgcccaaagccagaagcccggccccgagatggtctagtctctctggat
gaggtctcgggctgtggcaccctgcagagccgtagccccgaggacactgcagcctacttc
tgcatctacacctacccacgtggccgtcgagggggccggcgcagagctacgcggaccttc
cgggcggatggggccaccacttatgaggagaatcgtgcagaggcccagcgctgggccact
gccctcacgtgtctcctccgaggagtgcctctgtcaggggaccaggaaatcacccctgaa
ttgctgccccggaagcccaggctgctcatattggtcaatccctttggggggcggggcctg
gcctggcagcgctgtatggaccacgtggtgccaatgatctctgaagctgggctgtccttc
aacctcatacagacagaacgacagaaccatgcccgtgagctggtgcaggggttaagcctg
agtgagtgggaaggcattgtcactgtgtctggagacgggctgctttacgaggtgctgaat
gggctccttgatcggccagactgggaggatgccgtgcggatgcccattggtgtcctcccc
tgtggatcgggcaatgcgctagctggggcggtgaaccatcatggcgggtttgagcaggtt
gtcggtgttgacctgttgctcaactgctcgcttcttctctgccgtggtggcagccatcct
ctggacctgctctctgtgacgctagcctcgggatcccgctgtttttccttcctgtcagtg
gcctggggattcttgtcagatgtggacattcacagtgagcgcttcagggccctgggcagc
gctcgattcacactgggtgcagtgctaggcctggcctcgttgcatacctaccgtggacgc
ctctcctacctccccgctaccacagaaccagccttgcccatcccaggccacagtctgcct
cgagccaagtcagaactagtcttggctccagccccagcccccgccgccacccactcgcct
ctacatcgatctgtgtctgacctgcccctgccccttccccagcctgccttggtctcccct
ggctcccctgagcccctgcctgacctgtccctcaatggtggtggtccagagctgactgga
gactggggaggagctggggatgcacctctgtccccagacccactgctgccttcatccccc
aacgctctcaaaacagctcagctttcacccatcgctgaagggcccccagaaatgccagca
tcttcggggttcctgcctcccacccacagtgccccagaagcctctacctggggcccagtg
gaccacctcctccctcccctgggctctccactgccccaagactgggtgacaatagagggg
gagtttgtactcatgttgggcatcttgccgagccacctctgcgcagacctgatggcagcc
ccacatgcacgctttgatgatggcgttgtgcacctgtgttgggtgcggagcggcatctca
cgggctgcacttctacgcattttgctggccatggagcatggaaaccacttcagcctgggc
tgcccccatctgggctatgctgcagcacgtgccttccgccttgaaccactcacgcctcgt
ggcctgctcactgtagatggggagttagtggagtatgggccaatacaggcgcaggtgcac
ccaggtctcgccacgctgctcactgggcctgcaggtcaaaagccacaagcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (46)   
   RefSeq(nuc) (6)   
   GenBank (20)   
   EMBL (20)   
Protein domain (2)   
   Pfam (2)   
All databases (98)   

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