KEGG   Mus musculus (house mouse): 56720
Entry
56720             CDS       T01002                                 
Symbol
Tdo2, TDO, TO, chky
Name
(RefSeq) tryptophan 2,3-dioxygenase
  KO
K00453  tryptophan 2,3-dioxygenase [EC:1.13.11.11]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00380  Tryptophan metabolism
mmu01100  Metabolic pathways
mmu01240  Biosynthesis of cofactors
Module
mmu_M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
mmu_M00912  NAD biosynthesis, tryptophan => quinolinate => NAD
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    56720 (Tdo2)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.11  tryptophan 2,3-dioxygenase
     56720 (Tdo2)
SSDB
Motif
Pfam: Trp_dioxygenase
Other DBs
NCBI-GeneID: 56720
NCBI-ProteinID: NP_064295
MGI: 1928486
Ensembl: ENSMUSG00000028011
UniProt: P48776 Q8VCW3
Position
3:complement(81865719..81883035)
AA seq 406 aa
MSGCPFAGNSVGYTLKNVSMEDNEEDRAQTGVNRASKGGLIYGNYLQLEKILNAQELQSE
VKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVIARMHRVVV
IFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHY
RDNFGGDYNELLLKSEQEQTLLQLVEAWLERTPGLEPNGFNFWGKFEKNILKGLEEEFLR
IQAKTDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYRE
EPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGTKAGTGGSSGYHYLRSTVSDRYK
VFVDLFNLSTYLVPRHWVPKMNPIIHKFLYTAEYSDSSYFSSDESD
NT seq 1221 nt   +upstreamnt  +downstreamnt
atgagtgggtgcccgtttgcaggaaacagtgtaggatacactttgaaaaacgtatctatg
gaggacaatgaagaagacagagctcaaactggtgtaaacagagccagcaaaggaggactt
atctatggcaattacttgcagttggaaaagattttgaatgcgcaagaacttcagagtgaa
gtaaaagggaacaaaatccatgacgagcacctattcatcataactcatcaagcttatgaa
ctttggtttaaacaaatcctctgggaactagattctgttcgtgaaatcttccaaaatggc
catgtcagggatgagaggaacatgctcaaggtgatagctcggatgcatcgtgtggtggtc
atcttcaagctcctggtacagcagttctcggttctggaaacaatgactgctttggacttc
aatgacttcagagaatacctgtctccagcatcaggcttccagagtctacagttccggctg
ctggaaaataagattggtgttcttcagagcttgagagtcccttacaacaggaaacactat
cgtgataactttggaggagactacaatgagctgttgctgaaatcagagcaggagcagacg
ctgttgcagctggtggaggcatggctggaaagaacacctggtttagagccaaatggattt
aatttctggggaaagtttgaaaaaaatatcttgaaaggcctggaagaagaatttctaagg
attcaggctaaaaccgactctgaagaaaaagaggaacagatggcagagttccggaagcag
aaggaggtgctgctctgcttgtttgatgagaagcgtcatgactaccttctgagtaaaggt
gaacgacgactgtcataccgtgcactccagggagcactgatgatatatttttacagggag
gagcctcgattccaggtccctttccagctgctgacctcacttatggacattgacacgctc
atgaccaaatggagatataatcatgtgtgcatggtgcacagaatgctgggcaccaaggct
ggcactgggggatcctcaggctatcattacctgcgttcaactgtgagcgacaggtacaag
gtttttgtggatttatttaacctctcaacatatctggttcccagacactgggtaccaaag
atgaatccgatcattcacaaattcctttacacagccgagtacagtgacagctcttacttc
agcagcgatgaatcggattga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
Protein domain (1)   
   Pfam (1)   
All databases (52)   

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