KEGG   Mus musculus (house mouse): 59024
Entry
59024             CDS       T01002                                 
Symbol
Med12, 230kDa, Mopa, OPA-1, Tnrc11, Trap230
Name
(RefSeq) mediator complex subunit 12
  KO
K15162  mediator of RNA polymerase II transcription subunit 12
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04919  Thyroid hormone signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    59024 (Med12)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mmu03021]
    59024 (Med12)
Transcription machinery [BR:mmu03021]
 Eukaryotic type
  RNA polymerase II system
   Mediator complex
    CDK-module
     59024 (Med12)
SSDB
Motif
Pfam: Med12-LCEWAV Med12-PQL Med12
Other DBs
NCBI-GeneID: 59024
NCBI-ProteinID: NP_067496
MGI: 1926212
Ensembl: ENSMUSG00000079487
UniProt: A2AGH6 Q2NLB9
Position
X:100317697..100342540
AA seq 2190 aa
MAAFGILSYEHRPLKRLRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAK
NVNFNPAKISSNFSSIIAEKLRCNTLSDTGRRKSLMNQKDNFWLVTARSQSAINTWFTDL
AGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKKKNT
ADPFTEWTQIITKYLWEQLQKMAEYYRPGPAGSGGCGSTIGPLPHDVEMAIRQWDYNEKL
ALFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAY
FCTRRLALQLDGVSSHSSHVIAAQSTSSLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLV
FGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRA
KLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDS
LCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAE
RCGESEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLL
FCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPTDDPERKEAEGSSSSKLED
PGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPAKEKIE
GTLGILYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDIL
KVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHY
DQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFAIQLLNE
LSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGM
NRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSESNMRWAP
EFMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCA
ELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQ
CLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGI
RSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVPGGTEELPEEEGGGGSS
GRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQR
LMQLICYPHRLLDNEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNTEMNSLL
ENIAKATIEVFQQSAETGSSSGSTASNMPSSSKTKPVLSSLERSGVWLVAPLIAKLPTSV
QGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGL
LASLHSQVHQIVINWRENQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQ
LLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKK
LQKDLGERQSDSLEKVHQLLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQV
STKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYY
LEPLPLPPEDEEPPAPALLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATK
NEDYGMGPGRSGPYGVTVPPDLLHHANPGSISHLSYRQSSMGLYTQNQPLPAGGPRVDPY
RPVRLPMQKLPTRPTYPGVLPTTMSTVMGLEPSSYKTSVYRQQQPTVPQGQRLRQQLQAK
IQSQGMLGQSSVHQMTPSSSYGLQTSQGYTSYVSHVGLQQHTGPAGTMVPPSYSSQPYQS
THPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMMGTMTPLSA
QGVQAGVRSTSILPEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQQM
LRQQQQQQQQQQQQQQQQQQQQQQQQQQQPHQQQQQAAPPQPQPQSQPQFQRQGLQQTQQ
QQQTAALVRQLQQQLSNTQPQPSTNIFGRY
NT seq 6573 nt   +upstreamnt  +downstreamnt
atggcggctttcgggatcttgagctatgaacaccgacccctgaagcggctgcggctgggg
cctcccgatgtgtaccctcaagatcccaaacagaaggaggatgaactgacggctttgaat
gtaaaacaaggtttcaataaccagcctgctgtctctggggacgaacatggcagtgccaag
aacgtcaacttcaatcctgccaagatcagttccaacttcagcagcatcatcgcagagaag
ttaaggtgtaatactctctctgacactggtcgcaggaagtccctaatgaaccagaaggac
aacttctggctggtgactgcaagatctcagagtgctattaacacctggttcactgacctg
gctggcaccaaaccactcacacacctagccaaaaaggtccccattttcagtaaaaaggaa
gaagtatttgggtatttggccaaatacacggtgcctgtgatgcgggctgcctggctcatt
aagatgacttgtgcctactatgcagcaatgtctgagactaaggttaagaagaaaaatact
gctgaccccttcactgaatggactcaaatcatcacaaagtacttgtgggagcagctacag
aagatggctgagtactatcggccagggcctgcaggaagtggaggctgtggttctactata
gggcctttgccccatgatgtagagatggccatcaggcagtgggattacaatgagaagctc
gccttgttcatgtttcaggatggaatgctggacagacatgagttcctgacttgggtgctt
gagtgttttgagaaaatacgccctggagaagatgaattgcttaaattgctgcttccccta
ctgctgcgatactcaggggagtttgttcagtctgcctatctgtcccgccgccttgcctac
ttctgtacccggagattggctctccagctggatggtgtgagcagccactcatctcatgtc
atagctgctcagtcaacaagttctctgcccactaccccagcacctcagcccccaactagc
agtacaccctcgactccctttagtgacctgcttatgtgccctcagcatcgtcccctggtt
tttggcctcagctgtatccttcagaccatccttctgtgttgccctagtgccctagtttgg
cactactcattgactgatagccgaattaagaccggctcaccacttgaccacctgcctatt
gctccttccaacttgcccatgccagagggtaacagtgcctttactcagcaggtccgtgca
aaattacgagagatcgaacaacagatcaaggagcgtggacaagcagttgaggttcgctgg
tcttttgataagtgccaggaagctactgcaggtttcaccattggacgggtgctccatact
ttagaagtgctggatagccatagtttcgagcgctctgactttagtaactctcttgactcc
ctttgtaatcgaatctttggattggggcctagtaaggatggtcatgagatttcctctgat
gatgatgctgtggtatcattattgtgtgaatgggctgtaagctgcaaacgctcaggtcgg
catcgtgctatggtagtagccaaactcctagagaagagacaagcagaaattgaggctgag
cgctgcggagaatctgaagcagctgatgagaagggctccgtcgcctctggttccctttcc
gctcctagtgcacccattttccaggatgtcctcctgcagtttctggatacacaggctccc
atgctgactgatccccgaagtgaaagtgagcgagtagaattctttaacttggtactgctc
ttctgtgaactgatccgacatgatgtcttctcccataatatgtacacctgcactctcatc
tctcggggggatcttgcatttggagcccctggtcctcggcctccctctccctttgatgat
cctacagatgatccagagcgcaaggaggctgaaggcagcagcagcagcaagctagaggac
ccagggctctctgaatctatggacatcgaccctagttccagtgtgctttttgaggacatg
gaaaagcctgatttctcattgttctcccctactatgccttgtgaggggaagggaagccca
tcccctgagaaaccagatgtcgaaaaggaagtaaaacccccagccaaagagaagatcgag
gggacacttgggattctgtatgaccagccacgacatgtgcagtatgccacacactttcca
atcccacaggaggagtcatgcagccatgagtgcaaccagcggttggtcgtactgtttggg
gtggggaagcagcgagatgatgcccgccatgccatcaagaagattaccaaggatatcctg
aaggttctgaatcgcaaggggacagcagaaactgaccagcttgctcctattgtgcctctg
aatcctggagacctgacattcttaggtggggaagatgggcagaagcgacgacgcaaccgg
cccgaagccttccccactgctgaagatatttttgctaagttccagcacctttcccattat
gaccaacaccaggtcacggctcaggtctcccggaacgttctggagcagatcacgagcttc
gcccttggcatgtcgtaccacttgcctctggtgcagcatgtgcagttcatcttcgacctc
atggaatattcactgagcatcagtggcctcatcgactttgccatccagttactgaatgag
ctgagtgtggttgaggcggagctccttctcaaatcgtcggatctggtgggcagctacact
accagcctgtgcttatgtatcgtggctgtccttcgacactatcatgcctgcctcatcctc
aatcaggaccagatggcgcaagtgtttgaggggctctgtggcgtggtgaaacatggaatg
aaccgttcagatggctcctctgcagagcgctgtatccttgcttatctctatgatctgtat
acctcctgtagccatttaaagagcaaatttggggagctcttcagtgacttttgctcaaaa
gtgaagaacaccatctactgtaacgtggagccatcggaatccaatatgcgctgggcaccg
gagttcatgattgacactctggagaaccctgccgctcacactttcacctacacggggctc
ggcaagagtcttagtgagaaccctgctaaccgctatagctttgtgtgcaatgctcttatg
cacgtctgcgtgggccaccatgatcctgatagggtaaatgacatcgccatcctttgtgca
gagctgaccggctattgcaagtccttgagtgctgagtggctaggagtacttaaggccttg
tgctgctcctcgaacaatggcacttgtggtttcaatgatctcctgtgcaacgtagacgtc
agtgatttgtcttttcatgattccttggctacttttgttgctatcctcatcgcccgtcaa
tgtttgctcctagaagacctgattcgctgtgcagccatcccttcactcctcaatgctgct
tgtagtgagcaggattctgagccaggagccaggcttacttgccgaatcctcctccacctg
ttcaagacgccacaactcaatccttgccagtctgatggaaacaaacctactgttggaatc
cggtcctcctgtgaccgccacctgctggctgcctcccagaaccgcatcgtggatggggct
gtgtttgctgttctcaaggctgtgtttgtactcggagatgcggagctaaaaggttcaggc
tttactgtgccgggaggaacagaagaacttccagaagaggagggaggaggtggtagtagc
ggtcggagacagggtggccgcaacatctctgtggagacagcaagtctggatgtctatgcc
aagtacgtgctgcgaagcatctgccaacaggaatgggtaggagaacgttgccttaagtca
ctgtgtgaggatagcaatgatctacaagacccagtgttgagtagtgcccaggcccagcgc
ctcatgcaacttatctgctacccacatcgactgctggacaatgaggatggagaaaacccc
cagcggcagcgcattaaacgtattctcaagaatttagaccaatggaccatgcgccagtcc
tctttggagctacagttgatgatcaagcagacccccaacactgagatgaactctctcttg
gagaacattgccaaggccacaatcgaggttttccaacagtcagcagagacggggtcatct
tctggaagtacagcaagcaacatgcccagcagcagcaagaccaaacctgtgctcagctct
ctagagcgatctggtgtatggttggtggctcctctcattgccaaactgcccacttcagtc
cagggccatgtattaaaagctgctggggaggaactggaaaagggtcagcacctgggctct
tcttcccgtaaagaacgagatcgacagaaacagaagagcatgtccctgttgagccaacag
cctttcttatcactggtgctaacatgtctgaaaggacaggatgagcagcgcgagggactc
ctggcctccctccacagccaggtgcaccagattgtgattaattggcgagaaaaccagtac
ttagatgattgcaaaccaaagcagctaatgcatgaggcactcaaactgcggctcaacctg
gtggggggcatgtttgacactgtgcagcgtagtacccagcagactacagagtgggcccag
cttctccttgagatcatcatcagcggcactgtggacatgcagtctaacaatgagctcttc
actactgtgttggacatgctgagcgtgcttatcaacggaacgttggctgcagacatgtcc
agtatctcgcaaggcagcatggaggaaaacaagcgtgcatatatgaacctggtgaagaag
cttcagaaggacttgggggagcgccaatcagacagtctggagaaggttcaccaactgttg
ccactacccaagcagaaccgagatgtcataacctgtgagccacagggctcccttattgac
accaagggcaacaagattgctggcttcgattccatcttcaagaaggagggtctacaagtt
tctaccaaacaaaagatctctccctgggagctttttgagggcctgaagccatcaacagca
ccactgtcatgggcctggtttggcacagtccgagtggaccgcagagtggcacgaggggag
gagcagcagcggctgttgctctatcatacccacctgaggcctcgacccagagcctattac
ctggaaccactacctctgcccccagaagatgaggagccaccagcccctgccctactagag
cctgagaaaaaggctcctgagccccccaagactgacaaaccaggggctgctcctccgagc
actgaggagcgcaaaaagaagtctaccaagggcaaaaaacgcagccagccagccaccaag
aacgaggactatggcatggggccaggtcggagtggcccctatggtgtgacagtgcctcca
gaccttctacaccatgcaaatcctggttctatatcccaccttagctacaggcaaagctcc
atgggcctgtatacccaaaaccagccactacctgctggtggccctcgtgtggatccatac
cgccccgtgcgattaccaatgcaaaagctgccaactcgaccaacttatcccggtgtgctg
cctacaactatgtctactgtcatgggcctagaaccctcttcttataagacatctgtatac
cggcagcagcaacccacagtgccccagggacagcgccttcgccaacagctccaggcaaag
atacagagtcaggggatgttgggacagtcatctgtccatcagatgacccctagttcttcc
tatggtttgcagacttcccagggctatacatcctatgtttctcatgtgggattgcagcaa
cacacaggccctgcaggtaccatggtgccccccagctactccagccagccttatcagagc
acccacccttctaccaatcctactcttgtagatcctacccgccacctgcaacagcggccc
agtggctatgtgcatcagcaggccccaacctatgggcatggactgacttccactcaaagg
ttttcacaccagacactgcagcagacacccatgatgggtaccatgactccgttgagtgcc
cagggtgtccaggcaggcgtccgttcaacttccatcctgcctgagcagcagcaacaacaa
cagcagcagcagcaacagcagcagcagcaacagcagcagcagcaacaacaacagcagcag
cagcagcagcaacaacaacagcagtaccatatccgacagcaacagcagcagcagcagatg
ctacggcaacagcagcaacaacagcaacagcagcagcagcagcaacagcagcagcagcaa
caacaacagcaacagcagcagcagcagccacaccagcagcagcagcaggcagctcctccc
caaccccagccccagtcccagccccagttccagcgccagggcctgcagcagacccagcag
cagcaacagacagcagctttggtccggcaacttcaacaacagctctctaatacccagcca
cagcccagcaccaacatatttggacgctactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
Protein domain (3)   
   Pfam (3)   
All databases (55)   

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