KEGG   Mus musculus (house mouse): 625249
Entry
625249            CDS       T01002                                 
Symbol
Gpx4, GPx-4, GSHPx-4, PHGPx, mtPHGPx, snGPx
Name
(RefSeq) glutathione peroxidase 4
  KO
K05361  phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00480  Glutathione metabolism
mmu00590  Arachidonic acid metabolism
mmu01100  Metabolic pathways
mmu04216  Ferroptosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    625249 (Gpx4)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    625249 (Gpx4)
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    625249 (Gpx4)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.12  phospholipid-hydroperoxide glutathione peroxidase
     625249 (Gpx4)
SSDB
Motif
Pfam: GSHPx AhpC-TSA
Other DBs
NCBI-GeneID: 625249
NCBI-ProteinID: NP_032188
MGI: 104767
Ensembl: ENSMUSG00000075706
UniProt: O70325
Structure
Position
10:79883000..79892273
AA seq 197 aa
MSWGRLSRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVCLDKYR
GFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSNQEIKEFA
AGYNVKFDMYSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRY
GPMEEPQVIEKDLPCYL
NT seq 594 nt   +upstreamnt  +downstreamnt
atgagctggggccgtctgagccgcttacttaagccagcactgctgtgcggggctctggct
gcgcctggtctggcaggcaccatgtgtgcatcccgcgatgattggcgctgtgcgcgctcc
atgcacgaattctcagccaaggacatcgacgggcacatggtctgcctggataagtacagg
ggtttcgtgtgcatcgtcaccaacgtggcctcgcaatgaggcaaaactgacgtaaactac
actcagctagtcgatctgcatgcccgatatgctgagtgtggtttacgaatcctggccttc
ccctgcaaccagtttgggaggcaggagccaggaagtaatcaagaaatcaaggagtttgca
gccggctacaacgtcaagtttgacatgtacagcaagatctgtgtaaatggggacgatgcc
cacccactgtggaaatggatgaaagtccagcccaagggcaggggcatgctgggaaatgcc
atcaaatggaactttaccaagtttctcattgataagaacggctgcgtggtgaagcgctat
ggtcccatggaggagccccaggtgatagagaaggacctgccgtgctatctctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (44)   
   RefSeq(nuc) (4)   
   GenBank (20)   
   EMBL (20)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (83)   

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