KEGG   Mus musculus (house mouse): 68943
Entry
68943             CDS       T01002                                 
Symbol
Pink1, 1190006F07Rik, BRPK, mFLJ00387
Name
(RefSeq) PTEN induced putative kinase 1
  KO
K05688  PTEN induced putative kinase 1 [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04137  Mitophagy - animal
mmu05012  Parkinson disease
mmu05014  Amyotrophic lateral sclerosis
mmu05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    68943 (Pink1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    68943 (Pink1)
   05014 Amyotrophic lateral sclerosis
    68943 (Pink1)
   05022 Pathways of neurodegeneration - multiple diseases
    68943 (Pink1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    68943 (Pink1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    68943 (Pink1)
   03029 Mitochondrial biogenesis [BR:mmu03029]
    68943 (Pink1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     68943 (Pink1)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  NKF2 family
   68943 (Pink1)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    68943 (Pink1)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    68943 (Pink1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like
Other DBs
NCBI-GeneID: 68943
NCBI-ProteinID: NP_081156
MGI: 1916193
Ensembl: ENSMUSG00000028756
UniProt: Q99MQ3
Position
4:complement(138040718..138053631)
AA seq 580 aa
MAVRQALGRGLQLGRALLLRFAPKPGPLFGWGKPGPAAAWGRGERPGQVVSPGAQPRPVG
LPLPDRYRFFRQSVAGLAARIQRQFMVRARGGAGPCGRAVFLAFGLGLGLIEEKQAEGRR
AASACQEIQAIFTQKTKRVSDPLDTRCWQGFRLEDYLIGQAIGKGCNAAVYEATMPTLPQ
HLEKAKHLGLIGKGPDVVLKGADGEQAPGTPTFPFAIKMMWNISAGSSSEAILSKMSQEL
VPASRVALAGEYGAVTYRRSRDGPKQLAPHPNIIRVFRAFTSSVPLLPGALADYPDMLPP
HYYPEGLGHGRTLFLVMKNYPCTLRQYLEEQTPSSRLATMMTLQLLEGVDHLVQQGIAHR
DLKSDNILVEWDSDGCPWLVISDFGCCLADQHVGLRLPFNSSSVERGGNGSLMAPEVSTA
HSGPSAVIDYSKADTWAVGAIAYEIFGLANPFYGQGSAHLESRSYQEAQLPEMPESVPPE
ARRLVRSLLQREASKRPSARLAANVLHLSLWGEHLLALKNLKLDKMIAWLLQQSAATLLA
DRLREKSCVETKLQMLFLANLECEALCQAALLLSSWRAAP
NT seq 1743 nt   +upstreamnt  +downstreamnt
atggcggtgcgacaggcactgggccgaggcctgcagctgggtcgggcgctgctgctgcgc
ttcgcgcccaagcccggcccgctgttcggctgggggaagcccggccccgcggcggcctgg
ggccgcggagagcgcccaggccaggtcgtaagccccggagcacagcctcggccggtcggg
ctccccctcccggaccgctaccgcttcttccgccagtcggtagctgggctggcggcgcgg
atccagaggcagttcatggtgcgggcccggggcggcgcaggcccttgcggccgagcggtc
ttcctggccttcgggctggggctggggctgatcgaggagaagcaggcggaaggccggagg
gccgcctcggcctgtcaggagatccaggcaatttttacacagaaaaccaagcgcgtgtct
gacccactggacactcgatgctggcagggcttccgtctggaggattatctgatagggcaa
gccattggcaagggttgcaatgccgctgtgtatgaagccaccatgcccacgctgccccag
cacctggaaaaggccaaacaccttggccttataggaaagggcccggatgtcgtcctgaag
ggagcagacggggagcaggctccagggactcccacctttccctttgccatcaagatgatg
tggaatatctcggcaggttcctccagcgaagccatcttaagcaaaatgagccaggagctg
gtcccggcaagccgcgtggctttggctggagagtatggagcagttacttacagaagatcc
agagatggtcccaagcagcttgccccacaccctaacatcatccgggttttccgcgccttc
acctcatctgtgcccctcctgccgggggccctggctgactatcctgatatgctgccccca
cactactacccagaaggcctgggccacggtcgcacactgttcctcgttatgaagaactac
ccctgtaccctgcgccagtaccttgaggagcagactcccagttctcgcctggctaccatg
atgaccttgcagttgctggagggcgtggaccatctggttcagcagggcattgcccatcgg
gatctcaagtccgacaacatccttgtggagtgggactcagatggctgtccctggctagtg
atctcagactttggctgctgcctggctgaccagcatgttggcctgcggctgcctttcaac
agctccagtgtagagcgtggtggcaatggctccctgatggcccctgaggtgtccacagcc
cattctggccccagtgcggtaattgactacagcaaagccgatacctgggctgtgggggcc
atcgcctatgaaatctttgggcttgccaatcccttctatggccaaggcagtgcccacctc
gagagccgcagctaccaggaagctcagctgcctgagatgcctgagtcggtgcctccagag
gcaagacggctggtgaggtcactgctccagcgagaggccagcaagagaccgtctgcacgc
ttagctgcaaatgtgctgcacttaagcctctggggcgagcatcttctagccctgaagaac
ctgaaattggacaagatgatcgcctggctcttgcagcagtcagcagccactctgctggct
gacaggctgagagagaagagctgcgtggagacaaagctgcagatgctgtttctggctaac
ctggagtgtgaggctctctgccaggcagccctcctcctctcttcctggagggcagcccca
tga

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (80)   
   RefSeq(nuc) (2)   
   GenBank (39)   
   EMBL (39)   
Protein domain (3)   
   Pfam (3)   
All databases (114)   

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