KEGG   Mus musculus (house mouse): 69188
Entry
69188             CDS       T01002                                 
Symbol
Kmt2e, 1810033J14Rik, 9530077A04Rik, D230038D11Rik, Mll5, NKp44L
Name
(RefSeq) lysine (K)-specific methyltransferase 2E
  KO
K09189  [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00310  Lysine degradation
mmu01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    69188 (Kmt2e)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    69188 (Kmt2e)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     69188 (Kmt2e)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     69188 (Kmt2e)
SSDB
Motif
Pfam: SET PHD_5 PHD PHD_2
Other DBs
NCBI-GeneID: 69188
NCBI-ProteinID: NP_081260
MGI: 1924825
Ensembl: ENSMUSG00000029004
UniProt: Q3UG20
Position
5:23638034..23709233
AA seq 1868 aa
MSIAIPLGVDTTETSYLEMAAGSEPESVEASPVVVEKSNSFPHQLYTSSSHHSHSYIGLP
YADHNYGARPPPTPPASPPPSGLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR
CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRSLDKERAVLLQRRK
RENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVPKVTDKRRKKSGEKEQNFSK
CKKAFREGSRKSSRVKGSAPEIDPSSDSSNFVWETKIKAWMDRYEEANNNQYSEGVQREA
QRLAQRLGSGNDSKDMNKSELSTNNSLFRPPVESHIQKNKKILKSAKDLPPDALIIEYRG
KFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFIRRSCTPNAEVRHE
IEEGTIHLYIYSIQSIPKGTEITIAFDFDYGNCKYKVDCACLKENPECPVLKRSSESTEN
INSGYETRRKKGKKEKDTSKEKDIQNQNMTLDCEGTNNKIRSPETKQRKLSPLRLSVSNN
QEPDFIDDMEEKTPISNEVEMESEEQIAERKRKMTREERKMEAILQAFARLEKREKRREQ
ALERISTAKTEVKPECKESQVIADAEVVQEQVKEETAIKPAAAKVNRTKQRKSFSRSRTH
IGQQRRRHRTVSMCSDIPPSSPDIEVLSQQNEIENTVLAIEPETETAVAEIIPEAEVPAL
NKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDSLSERPLRITTDPEVLATQLNSLPGLTYS
PHVYSTPKHYIRFTSPFLSEKKRRKETTENISGSCKKRWLKQALEEENSTILHRYHSPCQ
ERSRSPTVNGENKSPLLLSDSCSLPDLTTPLKKRRLYQLLDTAYSESSTPTPSPYATPTH
TDITPTDPAFATPPRIKSDDETYRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEI
KRCTYNQEGYDRPSNMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRPCPGEKESV
SDLQLGLDAVEPAALQKSMETPAHDRTEPSNQLDSTHSGRGTMYSSWVKSPDRTGVNFSV
NSNLRDLTPSHQLETGGGFRVSESKCLIQQDDTRGMFLGAAVFCTSEDGLASGFGRTVND
NLIDGSCTPQNPPQKKKVSLLEYRKRQREARKSGSKPENFALISVSPHPSGSLSSSGDGC
VHSSENGEQAENQASLPLPPPAAAAAATAAAAYSASSEEGSSNCPVKDANSSEKKDPEVQ
WTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSPPSSHSNHIPQVHA
QSLAPSLSELMADPDAEGTEATSTSECPSPDTSQSPSKTSKPGSPGPINPAQSHGKILTK
PDSHWEATATVSEADNSVHQNPEPQHRQLSSNTPALSQNHAPQAHALSANDQLPQKLPSA
PTKLHCPPSPHTENPPKSSTPHTPVQHGYLSPKPPSQHLGSPFRPHHSQSPQVGTPQRET
QRNFYAAAQNLQANPQQATSGALFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSY
YQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGSTSQQSVPGHHVTPGHFLPSQNPT
IHHQPAAAAVVPPPPPPPPAPGPHLIQQPSSHQQHSVAHGVGPVHAVTPGSHIHSQTAGH
HLPPPPPPPGPAPHHHPPPHPTTGLQSLQAQHQHVVNSAPPPPPPPPPPPPASVLVSGHH
SASGQALHHPPHQGPPLFPASAHPAVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVAG
PHLQPQGPNSIPTPTASGFCPHPHPGSVALPHGVQGPQQASPVPAQIPIHRAQVPPTFQN
NYHGSGWH
NT seq 5607 nt   +upstreamnt  +downstreamnt
atgagcatagcgatcccattgggggttgatacaacagaaacatcctacttggaaatggct
gcaggctcagaaccggaatccgtagaagctagccctgtggtagttgagaaatccaacagt
tttccccaccagttatacaccagcagctcccaccactcacacagctacatcggtctgccc
tatgcggaccataattatggtgctcgtcctcctccaacacctccagcatcccctcctcca
tcaggtctcattagcaaaaacgaagtaggcatatttaccactcctaattttgatgaaact
tccagtgctactacaatcagcacatctgaagatggaagttacggtactgatgtaaccagg
tgcatatgtggttttacacatgatgacggatacatgatctgttgtgacaaatgcagtgtt
tggcaacatattgactgcatggggattgacaggcagcatattcctgatacatacctatgt
gaacgttgtcagcccaggagtttggataaagagagggcagtgctactgcaacgccggaaa
agagaaaatatgtcagatggtgataccagtgcaactgaaagtggtgatgaagttcctgtg
gaattatatactgcatttcagcatactccaacttcaatcactttaactgcttccagagtt
cccaaggttactgataaaagaaggaaaaaaagtggggagaaagaacaaaacttttcaaaa
tgtaaaaaagcctttcgtgaaggatctaggaaatcatcaagggttaagggttcagcacca
gaaattgatccttcatctgatagttcaaattttgtttgggaaacaaaaatcaaagcatgg
atggatcgttacgaagaagcaaataataaccaatatagtgaaggtgttcagagagaggca
caaagactagctcaaagactcggtagtgggaatgacagcaaagacatgaataaatcagaa
ttgagtaccaacaactcactcttcagacctcctgtagagagccatatacagaagaataaa
aaaattctgaaatctgccaaagacttgcctcctgatgcacttatcattgaatatagaggg
aagtttatgctgagagaacagtttgaagcaaatggatatttctttaaaaggccataccct
tttgttttattctactctaagttccatgggcttgaaatgtgtgttgatgcgaggactttt
gggaatgaggctcgattcatcaggcgttcttgtacaccgaatgcagaggtgaggcatgaa
attgaagaggggaccatacatctctacatttattctatacagagtattccaaaagggact
gaaattaccattgcctttgattttgactacgggaattgcaaatacaaggtggactgtgca
tgcctcaaggaaaatccagagtgccctgttctcaagcgaagctcggaatccacagaaaac
atcaatagtggttatgagaccagaaggaaaaaaggaaaaaaagagaaagatacttcaaaa
gaaaaagacatacaaaatcagaatatgactttggactgtgaaggaacaaacaacaaaata
aggagtccagaaacaaaacagagaaagctttctccattgaggctgtcggtgtcaaacaac
caggaaccagattttattgatgatatggaagaaaaaactcctattagcaatgaagtggaa
atggaatctgaggaacagattgcagaaaggaaaaggaagatgacaagagaagaaagaaaa
atggaagcaattttgcaggcttttgccagacttgagaagagagagaaaagacgagaacaa
gctttggaaaggatcagcacagctaagacagaagttaagcctgaatgcaaagagtcgcag
gtcatcgccgatgccgaagtggtgcaggaacaagtaaaagaagaaactgctatcaagcca
gccgctgccaaagtgaacagaactaagcagagaaagagcttttctcgtagtaggactcac
attggacagcagcgtcggagacacagaactgtcagcatgtgttcagacataccgccatct
tctcctgacatcgaagttctgtcacaacagaacgagattgaaaatactgtacttgctata
gaaccagaaactgaaactgcagtagcagaaataattcctgaagcggaagttccagcactt
aataagtgtcccacaaagtaccccaaaacaaagaagcacttggtcaatgaatggttaagt
gagaagaatgagaagacaggaaaaccttcagacagcctttcagaaaggcctctgcgcata
actacagatccagaggtgttagctacacagctcaattctttgccaggtctcacttacagc
ccccatgtatactctactcctaagcattatattagatttacatcaccattcctttcggaa
aaaaagagaagaaaagaaactactgaaaacatttctggctcatgcaaaaagcggtggctg
aagcaagccctggaggaagaaaattcaacaattttacatagatatcattcaccttgtcag
gaaagatccaggagtcctacagttaatggtgaaaacaaaagtccacttctgctaagcgac
agctgctccctcccagatttaaccacaccactaaaaaagcgaagactttaccaattgtta
gatactgcttactcagaaagctccactcctaccccttcaccatatgctacaccaactcac
acagacatcactcctacggacccagcatttgccactcccccacggatcaaatcagatgat
gaaacttacagaaatggttataaacccatatattcaccagtgacccctgtaacccctggc
acaccaggaaacaccatgcactttgagaatatttcttccccagaaagttctccagaaata
aagagatgcacttacaatcaagagggatatgaccgaccttcaaacatgctaacgttgggg
ccttttagaaattccaatttaactgagctgggcctgcaagaaataaagactattggttat
accagccctaggagcaggactgaggttaacaggccttgcccaggggagaaggagtctgtg
tcagaccttcaactgggactcgatgcagtcgagccagctgccttacagaaatccatggaa
acaccagcccatgacaggactgagcccagcaaccaactggattcgacccactctggacgg
ggcacaatgtattcatcctgggtaaagagtcctgacagaacaggagttaacttctcagta
aactccaacttgagggacttaacaccctctcatcagttggagactggaggcggcttccga
gtaagtgagtccaagtgcctgattcagcaggatgacactagaggcatgtttctgggagcg
gctgtcttttgtacttctgaagacgggcttgcctctggttttggacggactgttaatgac
aatttgatcgacgggagttgcacgccccagaatccaccacaaaagaaaaaggtttctcta
ttagaataccgtaagagacaacgtgaagctaggaagagtgggtctaagccagagaacttt
gctttgattagtgtgtcacctcacccgagtgggagcctgagcagcagtggcgacgggtgt
gtccacagcagtgaaaacggggagcaggcagaaaaccaggctagcttgcctttaccaccg
cctgctgccgccgccgccgccaccgccgccgccgcttacagtgcctcttctgaagaaggc
agcagtaactgtcctgttaaagacgccaattccagtgagaagaaagacccagaagttcag
tggactgcctccacttcagtggagcaagtgagagagagaagttaccagagagccttactg
ctcagtgaccaccgcaaagacaaagacagtgggggagagtcaccatgtgtctcatgctca
ccgagtcatgttcagtctccaccttcatctcattcaaatcacattccccaggtgcacgct
cagagcctagctccttctttgagtgaactcatggcagaccctgatgcggaaggtacagaa
gccacaagtacaagtgaatgtccatcccctgacacttctcagagcccttctaaaacaagc
aagcctggttcaccagggccaatcaatcctgctcagtcacatgggaaaatactcacaaaa
ccagatagccactgggaggcaactgccactgtatcagaagctgacaacagtgttcaccaa
aacccagagcctcagcacagacagctgtcaagtaacaccccagcactttctcagaaccat
gctcctcaggcccacgctctgagtgcgaatgatcaacttccgcaaaagctgccttctgca
ccgacgaagttgcactgtcctccgtcacctcacacagaaaaccctcccaagtcctccaca
cctcacacccccgtgcagcatggttacctctcgccaaagcctccttcacagcacttagga
tctcccttcaggcctcaccattcacaatcacctcaagttggaactcctcaacgagagact
cagagaaacttttatgcagcggcacagaaccttcaagctaatcctcagcaggcaacttct
ggagcgttatttacccagacaccctcaggacaatcttcagcaacctacagtcagttcaac
caacagagtctcaacagcacggccccaccccctccccctcctccccctccttcatcctac
tatcaaaaccagcagccctctgcaaactttcagaattataatcagctaaaaggtagtctt
tcccaacaaactgtgtttacatctggaccaaatcaagcacttcctggcagcaccagccag
caatcagttcctggacatcacgttactccagggcattttctgccatctcaaaaccccacc
attcaccatcaacctgctgctgctgctgtggtcccgcccccgcccccacccccgcccgct
ccaggaccacacctcatacagcagccaagctcacatcagcagcactctgtagcacatgga
gttgggccagttcatgctgttacccctgggtcacacattcattctcaaactgcaggacac
catttaccaccaccccctccaccacctggtcctgccccacatcaccatcccccaccccat
cctaccacgggactgcaaagtctacaagcacaacaccagcatgtagtaaactcggcaccc
ccgccccctccccctcccccgccccctcccccagccagtgttctggtttctgggcatcat
tcagcatcaggtcaagccttacaccacccacctcatcaaggacctccacttttccctgca
agcgctcatccagctgtcccgccgtacccctcacaagccacacatcataccactttggga
ccgggaccccaacaccagccttccggaacagggccacattgtccattaccagttgcaggt
cctcatctccagccccaaggaccaaacagtattccaacccctactgcttcagggttctgt
cctcatcctcatcctggctctgtggccctgccacatggggtgcaaggacctcagcaggca
tcgccagtgcctgcacagattccaattcacagagcacaggtgccgccgacatttcaaaac
aattaccacggttcagggtggcattaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (78)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (70)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (44)   
   RefSeq(nuc) (8)   
   GenBank (18)   
   EMBL (18)   
Protein domain (4)   
   Pfam (4)   
All databases (150)   

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