KEGG   Mus musculus (house mouse): 71586
Entry
71586             CDS       T01002                                 
Symbol
Ifih1, 9130009C22Rik, Helicard, Hlcd, MDA5, RLR-2
Name
(RefSeq) interferon induced with helicase C domain 1
  KO
K12647  interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04622  RIG-I-like receptor signaling pathway
mmu05161  Hepatitis B
mmu05162  Measles
mmu05164  Influenza A
mmu05168  Herpes simplex virus 1 infection
mmu05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    71586 (Ifih1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    71586 (Ifih1)
   05171 Coronavirus disease - COVID-19
    71586 (Ifih1)
   05164 Influenza A
    71586 (Ifih1)
   05162 Measles
    71586 (Ifih1)
   05168 Herpes simplex virus 1 infection
    71586 (Ifih1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:mmu04054]
    71586 (Ifih1)
Enzymes [BR:mmu01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.6  RNA 3'-5' helicase
     71586 (Ifih1)
Pattern recognition receptors [BR:mmu04054]
 Cytoplasmic pattern recognition receptors
  RIG-I-like receptors
   71586 (Ifih1)
SSDB
Motif
Pfam: CARD_2 RIG-I_C-RD RIG-I_C ResIII Helicase_C DEAD CARD SNF2-rel_dom SWI2_SNF2 DUF3638 AAA_19 MoCF_biosynth
Other DBs
NCBI-GeneID: 71586
NCBI-ProteinID: NP_082111
MGI: 1918836
Ensembl: ENSMUSG00000026896
UniProt: Q8R5F7 Q3TGP5 D2CGM4
Structure
Position
2:complement(62426137..62476599)
AA seq 1025 aa
MSIVCSAEDSFRNLILFFRPRLKMYIQVEPVLDHLIFLSAETKEQILKKINTCGNTSAAE
LLLSTLEQGQWPLGWTQMFVEALEHSGNPLAARYVKPTLTDLPSPSSETAHDECLHLLTL
LQPTLVDKLLINDVLDTCFEKGLLTVEDRNRISAAGNSGNESGVRELLRRIVQKENWFST
FLDVLRQTGNDALFQELTGGGCPEDNTDLANSSHRDGPAANECLLPAVDESSLETEAWNV
DDILPEASCTDSSVTTESDTSLAEGSVSCFDESLGHNSNMGRDSGTMGSDSDESVIQTKR
VSPEPELQLRPYQMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQASESGKV
IVLVNKVMLAEQLFRKEFNPYLKKWYRIIGLSGDTQLKISFPEVVKSYDVIISTAQILEN
SLLNLESGDDDGVQLSDFSLIIIDECHHTNKEAVYNNIMRRYLKQKLRNNDLKKQNKPAI
PLPQILGLTASPGVGAAKKQSEAEKHILNICANLDAFTIKTVKENLGQLKHQIKEPCKKF
VIADDTRENPFKEKLLEIMASIQTYCQKSPMSDFGTQHYEQWAIQMEKKAAKDGNRKDRV
CAEHLRKYNEALQINDTIRMIDAYSHLETFYTDEKEKKFAVLNDSDKSDDEASSCNDQLK
GDVKKSLKLDETDEFLMNLFFDNKKMLKKLAENPKYENEKLIKLRNTILEQFTRSEESSR
GIIFTKTRQSTYALSQWIMENAKFAEVGVKAHHLIGAGHSSEVKPMTQTEQKEVISKFRT
GEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVTSSGSGV
TEREIVNDFREKMMYKAINRVQNMKPEEYAHKILELQVQSILEKKMKVKRSIAKQYNDNP
SLITLLCKNCSMLVCSGENIHVIEKMHHVNMTPEFKGLYIVRENKALQKKFADYQTNGEI
ICKCGQAWGTMMVHKGLDLPCLKIRNFVVNFKNNSPKKQYKKWVELPIRFPDLDYSEYCL
YSDED
NT seq 3078 nt   +upstreamnt  +downstreamnt
atgtcgattgtctgttctgcagaggacagcttcaggaatctcatcttattcttcaggccc
aggctgaaaatgtacattcaggtggagccagtgctggaccacctcatctttctgtctgca
gaaaccaaagagcagattcttaaaaagatcaacacctgtggtaacaccagcgcggcagaa
ctgctgctgagcaccttggagcagggacaatggcctctgggatggacgcagatgttcgtg
gaggccctagagcacagtggcaatcccctagccgcgcgctatgtcaaacccacactcact
gatctgccctctccttcctctgagactgcccatgacgagtgtctccacttgctgaccctc
ctccagcccactttggtggacaaacttctgattaacgatgtcttggacacttgcttcgag
aagggactattgacagtcgaagacagaaatcggatttctgctgcaggaaacagcgggaat
gagtcaggtgtaagagagctgctgagaaggattgtgcagaaggaaaactggttttctacc
ttcctggatgttctgcgccaaactggaaatgatgcactattccaagaactaacaggtgga
ggctgcccagaagacaacacagacttggctaactcgtctcacagagatgggcctgcagct
aatgagtgtcttctgcctgctgtcgatgagtcaagtctggagacagaggcctggaacgta
gacgacatattaccagaggcttcttgtacagattcgtctgtgaccacagaatcagacaca
agtttggcagaaggaagtgtcagctgcttcgatgaaagtcttggacataacagcaacatg
ggcagggattcaggcaccatgggaagtgattcagatgaaagtgtcatccagacaaaaaga
gtatcccccgagccagaactgcagctcaggccttaccaaatggaagtggcccaaccagct
ctagatgggaagaatattattatctgcctccccacggggagtgggaaaaccagagtggct
gtttacatcaccaaagatcacttagacaagaagaagcaggcatctgaatccgggaaggtt
atcgttcttgtcaataaggtaatgttagcagaacaacttttccgaaaagagttcaaccca
tatttgaagaaatggtatcgaattattggattaagtggcgatacccagctgaaaatatca
tttccagaagttgtcaaatcttacgatgttattatcagcactgctcaaatccttgaaaac
tccctcttaaatctggagagtggagacgatgacggtgtgcagctgtcagacttctctctc
attatcattgatgagtgccatcacaccaacaaggaggcagtctataacaacatcatgaga
cgatatttgaagcagaagctgagaaacaatgacctcaagaaacaaaacaaaccagccatt
cccctgccgcagatactaggactgacagcttcacctggtgttggagcagccaaaaagcag
tctgaggctgaaaaacatattttaaatatatgtgccaatcttgatgcctttaccattaaa
acagtgaaagagaatcttggtcaactcaaacaccaaataaaggaaccatgcaagaaattt
gtgattgctgatgacaccagagaaaatccatttaaagagaaacttctagaaattatggca
agcattcagacttactgccaaaaaagtccaatgtcagattttggaacccaacattatgag
cagtgggccattcaaatggagaaaaaagctgctaaagacggaaatcgcaaagatcgcgtc
tgtgcagaacatttgaggaagtacaacgaagccctacaaatcaacgacacgatccgaatg
attgatgcatatagccacctggagacattctacactgatgagaaagaaaagaagttcgca
gtcctcaatgacagcgacaagagtgatgacgaggccagcagttgcaatgaccaacttaag
ggcgatgtaaagaaatctttgaaactggacgaaacggatgaatttctcatgaatttgttc
tttgataacaagaaaatgttgaaaaaactagctgaaaacccaaaatacgagaatgaaaaa
ctcattaaattaagaaacacgatactggaacaattcacaaggtctgaggagtcctcccga
ggaattatttttacaaaaacacgacagagcacctacgcactttcccagtggatcatggaa
aatgcaaagtttgcggaagttggagtcaaagcgcatcacctgattggcgcggggcacagc
agtgaagtcaagcccatgactcagactgaacaaaaagaagtcattagtaaatttcgcact
ggcgaaataaatctgcttatcgctacgacggtggcagaggaaggcctggatatcaaagag
tgcaatattgttattcgttatggccttgtcacgaacgagatagccatggtccaggcccgg
ggtcgagccagagctgatgaaagcacgtatgtcctggtcaccagcagtggctcaggagtt
accgaacgggagattgttaatgatttccgagagaagatgatgtataaagctattaaccgt
gttcaaaacatgaaaccagaggagtatgcacataagattttggaattgcaggtgcaaagt
atcctggaaaagaaaatgaaagtcaaaagaagcattgcaaagcaatacaacgacaatcca
tcgttaataacacttctctgcaaaaattgtagcatgctggtctgctcgggagaaaacatc
catgtcattgagaagatgcatcatgtcaatatgacaccagaattcaagggactctacatt
gtaagagaaaacaaagcactgcaaaagaaatttgctgattatcagaccaatggagagatt
atctgcaagtgtggccaggcttggggaacaatgatggtgcacaaaggtttagatttgcct
tgtcttaaaataaggaattttgtagtcaatttcaaaaataactcaccgaagaaacagtac
aagaagtgggtggaattgcctatcagatttcctgatcttgactactcagaatactgcttg
tatagtgatgaagattag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (39)   
   RefSeq(nuc) (3)   
   GenBank (18)   
   EMBL (18)   
3D Structure (14)   
   PDB (14)   
Protein domain (12)   
   Pfam (12)   
All databases (102)   

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