KEGG   Mus musculus (house mouse): 71745
Entry
71745             CDS       T01002                                 
Symbol
Cul2, 1300003D18Rik, 4932411N15Rik, mKIAA4106
Name
(RefSeq) cullin 2
  KO
K03870  cullin 2
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04066  HIF-1 signaling pathway
mmu04120  Ubiquitin mediated proteolysis
mmu05200  Pathways in cancer
mmu05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    71745 (Cul2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    71745 (Cul2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    71745 (Cul2)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    71745 (Cul2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mmu04121]
    71745 (Cul2)
Ubiquitin system [BR:mmu04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul2 complex
    Cullin
     71745 (Cul2)
SSDB
Motif
Pfam: Cullin Cullin_Nedd8 Rio2_N TFIIE_alpha
Other DBs
NCBI-GeneID: 71745
NCBI-ProteinID: NP_083678
MGI: 1918995
Ensembl: ENSMUSG00000024231
UniProt: Q9D4H8
Position
18:3382970..3436700
AA seq 745 aa
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYAE
TKIFLESHVRHLYKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQYIKKNKLTE
ADIQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQNILIRMLLREIKNDRGGEDPNQKV
IHGVINSFVHVEQYKKKFPLKFYQGIFVSPFLTETGEYYKQEASNLLQESNCSQYMEKVL
GRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADHLQFLHSECHSIIQQERKNDMANMYVL
LRAVSSGLPHMIEELQKHIHDEGLRATSNLTQEHMPTLFVESVLEVHGKFVQLINTVLNG
DQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVEDKLTSFIT
VFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDM
SVSADLNNKFNNFIRNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMF
ELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQ
DSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMSFSSKRTKFKITTSMQKD
TPQELEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKK
CIEVLIDKQYIERSQASADEYSYVA
NT seq 2238 nt   +upstreamnt  +downstreamnt
atgtctttaaaaccaagagtagtggattttgatgagacatggaacaaactcctaactaca
atcaaagctgttgttatgttggaatatgtcgagcgagcaacatggaatgaccgcttctca
gatatctatgctttatgtgtggcctatcctgaaccacttggagaaagactttatgcggaa
acaaagatttttttggaaagtcacgttcggcatttgtataagagagttctggagtctgaa
gaacaagtgcttgttatgtatcataggtactgggaagaatacagcaaaggcgccgactat
atggactgcttatataggtatctcaatacccagtatattaaaaagaataaattgacagaa
gctgatatacagtatggctatggtggagtagatatgaatgaaccacttatggaaatagga
gagctagcattggatatgtggaggaagttaatggttgaaccccttcagaacatcctcatc
cggatgctgcttcgagaaattaaaaatgatcgtggtggtgaagatccaaaccagaaagta
atccatggggttattaactcctttgttcatgttgaacagtataagaaaaaatttccctta
aagttttatcagggaatattcgtgtctccctttctgactgaaacgggagaatattacaag
caagaagcttcaaatttattacaagaatcaaattgttcacagtatatggaaaaggttcta
ggtagattaaaagatgaagaaattagatgtcgaaaatatttgcatccaagttcatatact
aaagtgattcatgagtgtcagcagcggatggtagcagaccacttacagttcttacattca
gagtgccacagcatcattcagcaagagaggaagaacgacatggcaaatatgtacgtctta
ctccgtgctgtgtccagtggtttacctcatatgattgaggagctgcagaaacatatccat
gacgagggcctcagagcgaccagtaaccttactcaggaacatatgccaacactatttgtg
gaatcagttttggaagtacatggtaaattcgttcaacttatcaacactgttttgaatggt
gatcagcattttatgagtgctttagataaggcccttacatctgttgtaaattacagagaa
cccaagtctgtttgcaaagcgcctgaactgcttgctaagtactgtgacaacttgctaaag
aagtcagcgaaggggatgactgaaaatgaagtggaggacaagctcactagcttcatcaca
gttttcaagtacattgatgacaaggacgtctttcagaagttctatgcaagaatgctagca
aaacgtctaattcacgggttgtctatgtctatggattctgaagaagccatgatcaataaa
ttaaagcaagcctgtggttatgagtttaccagcaagctgcatcgaatgtatacagacatg
agtgtcagcgctgatttgaacaataagttcaacaatttcatcagaaaccaagacaccgtg
attgacttggggattagtttccaaatatatgttcttcaggctggtgcgtggcctctcact
caggctccttcatctacatttgcaattccccaagagctagagaaaagtgtacagatgttt
gaattgttttatagccagcatttcagtggacggaagctgacatggttgcattatctctgt
acaggtgaagttaaaatgaactatttgggaaaaccatatgtagctatggttacaacctac
caaatggcagttcttcttgcctttaacaacagtgaaactgtcagctacaaagaacttcaa
gacagtacccagatgaatgaaaaggagctgaccaaaacaatcaaatcattacttgatgtg
aaaatgattaaccatgattcagaaaaggaagatatcgatgcagaatcttcattttcatta
aatatgagcttcagcagtaagagaacaaaatttaagattactacgtcaatgcagaaggat
acgccacaagaactggaacagactagaagtgctgtagatgaggaccggaaaatgtatctt
caagctgctattgtccgcatcatgaaagcacgaaaagtgcttcggcacaacgccctcatt
caagaggtaatcagccagtcaagagccaggttcaatcccagtatcagcatgattaagaag
tgcatagaagttctgatagacaaacagtacatcgagcgcagccaagcatctgcagatgaa
tacagttacgtcgcatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (26)   
   RefSeq(nuc) (4)   
   GenBank (11)   
   EMBL (11)   
Protein domain (4)   
   Pfam (4)   
All databases (59)   

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