KEGG   Mus musculus (house mouse): 72198
Entry
72198             CDS       T01002                                 
Symbol
Mtrex, 2610528A15Rik, Skiv2l2, mKIAA0052
Name
(RefSeq) Mtr4 exosome RNA helicase
  KO
K12598  ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03018  RNA degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    72198 (Mtrex)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    72198 (Mtrex)
   03041 Spliceosome [BR:mmu03041]
    72198 (Mtrex)
   03009 Ribosome biogenesis [BR:mmu03009]
    72198 (Mtrex)
   03016 Transfer RNA biogenesis [BR:mmu03016]
    72198 (Mtrex)
Enzymes [BR:mmu01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.6  RNA 3'-5' helicase
     72198 (Mtrex)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    TRAMP complex
     72198 (Mtrex)
Spliceosome [BR:mmu03041]
 Complex B
  U4/U6.U5 tri-snRNP components
   U4/U6.U5 tri-snRNP related factors
    72198 (Mtrex)
 Complex C
   U4/U6.U5 tri-SnRNP related factors
    72198 (Mtrex)
Ribosome biogenesis [BR:mmu03009]
 Eukaryotic type
  Pre-60S particles
   Helicases
    72198 (Mtrex)
Transfer RNA biogenesis [BR:mmu03016]
 Eukaryotic type
  tRNA degradation factors
   TRAMP complex
    72198 (Mtrex)
SSDB
Motif
Pfam: MTR4_beta-barrel DSHCT DEAD MTR4-like_stalk Helicase_C ResIII nSTAND3 AAA_22
Other DBs
NCBI-GeneID: 72198
NCBI-ProteinID: NP_082427
MGI: 1919448
Ensembl: ENSMUSG00000016018
UniProt: Q9CZU3
Position
13:complement(113004306..113063914)
AA seq 1040 aa
MADAFGDELFSVFEDDSTSAAGAKKDKEKEKWKGPPGSADKAGKRLDTKLQSESASGGKN
KRDLDVEGTDEPIFGKKPRIEDSINEDLSLADLMPRVKVQSVETVEGCTHEVALPADEDY
IPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREK
QRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEV
MREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQ
PCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQK
GRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEE
VFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFAT
ETFAMGINMPARTVLFTNARKYDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEK
MSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVV
EKVKNSEEQYNKIVIPNEENVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKV
KNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDE
KGEMQVVPVLVHLLSAISTVRLYIPKDLRPVDNRQSVLKSIQEVQRRFPDGVPLLDPIDD
MGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCERKAQIALDIKSAKRELKKA
RTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSS
EQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSF
KPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENK
FAEGITKIKRDIVFAASLYL
NT seq 3123 nt   +upstreamnt  +downstreamnt
atggcggatgctttcggggatgagcttttcagcgttttcgaggatgattcgacctctgca
gcaggagccaagaaagacaaagagaaagagaaatggaaggggccaccagggtctgcagac
aaggccgggaaacgactggataccaaattacaatcagagtcagccagtggggggaaaaac
aaaagagatctagatgttgaaggcactgatgaacctatttttggcaagaagccgagaata
gaagactcaattaatgaagatttaagcctggcggacctgatgcccagagtcaaggtacag
tcagtggaaacagttgaaggctgcacacatgaggtcgctcttcctgcagatgaggattat
ataccacttaaacctcgagttgggaaggcagcaaaggaatacccattcattcttgatgct
ttccaaagagaagccattcagtgtgttgataataaccagtctgtgctagtatctgctcat
acgtcagcagggaagaccgtgtgtgccgagtatgctattgcattggctttaagagaaaaa
cagcgtgtaatatttaccagccctattaaggctctaagtaatcagaaataccgtgaaatg
tatgaagaatttcaagatgtggggctgatgacgggagatgttactattaatcccacagca
tcttgtctcgttatgactacagagattttgagaagtatgctgtatagaggctctgaagtt
atgcgagaagttgcttgggtcatatttgatgaaattcattacatgagagattcagagcgt
ggtgtagtatgggaagaaactattattttgcttccagataatgttcactatgtctttctt
tcggctactattccaaatgctcgacagtttgctgaatggatttgtcacctacataaacag
ccctgtcatgttatttacactgattatcgacccactccactgcaacactacatatttcca
gcagggggagatggccttcacctggtggttgatgaaaatggtgacttcagagaagataat
tttaacactgcaatgcaagtgctgcgggatgcaggtgatttggccaaaggagaccagaag
ggacggaaaggaggaacaaaaggtccatcaaatgtgttcaagattgtgaagatgattatg
gagagaaatttccagcctgtgatcatcttcagtttcagtaagaaggactgtgaagcatat
gctcttcagatgacgaagctagacttcaacacagatgaagaaaagaagatggttgaagaa
gttttcaataatgcaattgactgcttgtctgatgaagataaaaagctccctcaggttgaa
catgtgcttccacttttgaagcgggggattggtattcaccatggtggcttacttcctatt
ttgaaagaaactatagaaattctcttttctgaaggattgataaaggctttatttgccaca
gagacttttgctatgggaattaacatgccagctagaactgttttatttacaaatgcccgt
aaatatgacggaaaggacttcagatggatttcctctggcgagtacatccagatgtctggt
cgcgcaggaaggagaggcatggacgacagagggattgtgattcttatggtagacgagaag
atgagcccaactattggaaagcagctgcttaaggggtcagctgatcctctgaacagtgct
ttccatctgacctataacatggttttgaacttactaagagtagaagaaattaaccccgag
tacatgcttgaaaaatccttctaccagtttcagcattatagagcaattccaggggtcgta
gaaaaggtaaagaactcagaagagcagtataataaaatagtcattcccaatgaagaaaat
gtggtcatctattacaagattagacagcaacttgccaagctgggaaaagagattgaagaa
tatattcataaaccaaagtactgcttaccctttctacagccaggccgtttggtaaaggtg
aaaaatgaaggcgatgatttcggctggggagtagtagtgaacttctcaaaaaagtcaaat
gtcaagcccaattctggcgaactggatcccttgtatgtggtggaagtcctcctgcgctgt
agcaaggaaagcctgaagaactcagccaccgaggcagcaaagccagcgaagccagacgag
aaaggggagatgcaggttgttccagttttggtgcatctcctgtctgccatcagcactgtc
aggctctatattccaaaagaccttcgacctgtggacaacagacagagtgtcttaaaatcc
atacaggaagttcaaaggcgctttcccgacggcgttcctctgttagatccgatcgatgat
atgggcatccaagatcaaggactgaagaaagtcatccagaaagtagaggcctttgagcat
cgcatgtactcacacccactccacaatgatcctaacttggaaactgtttatacactgtgt
gaaagaaaggcccagattgcactagatatcaagtctgcaaagagagaactgaagaaggca
agaactgttctgcaaatggacgagctcaaatgccgcaagcgcgtgctgagacggctgggc
tttgcgacatcgtcggatgtcatagagatgaaaggacgggtggcttgtgaaataagcagt
gcggacgagctccttctaacggagatgatgttcaatgggcttttcaatgacctttcttca
gagcaggcaaccgcactgttaagctgttttgtgtttcaagagaattctagtgagatgccc
aaactaacagagcagttagctggaccactccgacaaatgcaggaatgtgctaaaaggatt
gcaaaagtttcagcagaggcaaagctggagattgatgaagaaacttacctaagctcattc
aagcctcacctgatggatgtggtgtatacctgggcaactggggccacatttgcccatatc
tgcaaaatgacagatgttttcgaaggcagtataattcgttgtatgaggcgtctggaagaa
ctgcttcgacagatgtgtcaagcagcaaaagccattggaaacacagagctggagaacaaa
tttgctgaaggaattaccaaaatcaagagggatattgtatttgctgccagcctctactta
tag

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (16)   
   RefSeq(nuc) (2)   
   GenBank (7)   
   EMBL (7)   
Protein domain (8)   
   Pfam (8)   
All databases (63)   

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