KEGG   Mus musculus (house mouse): 73341
Entry
73341             CDS       T01002                                 
Symbol
Arhgef6, 1600028C08Rik, 1700038J06Rik, 4930592P22Rik, alpha-PIX
Name
(RefSeq) Rac/Cdc42 guanine nucleotide exchange factor 6
  KO
K05729  Rho guanine nucleotide exchange factor 6
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04810  Regulation of actin cytoskeleton
mmu05212  Pancreatic cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    73341 (Arhgef6)
 09160 Human Diseases
  09162 Cancer: specific types
   05212 Pancreatic cancer
    73341 (Arhgef6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    73341 (Arhgef6)
Membrane trafficking [BR:mmu04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    73341 (Arhgef6)
SSDB
Motif
Pfam: RhoGEF67_u2 betaPIX_CC RhoGEF CH SH3_2 SH3_9 SH3_1 PH RhoGEF67_u1 CAMSAP_CH DUF2204 ZapB HetE-N
Other DBs
NCBI-GeneID: 73341
NCBI-ProteinID: NP_690014
MGI: 1920591
Ensembl: ENSMUSG00000031133
UniProt: Q8K4I3 F6WMJ3
Structure
Position
X:complement(56276845..56384119)
AA seq 771 aa
MNPEERLVTWLISLGVLESPKKTVCDPEEFLKSSLKNGVVLCKLINRLLPGSVEKYCLEP
QTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCG
RSSSLSAATSSQTNPQVAVPSTAPEQHSEEKAEMTENGSHQLIVKARFNFKQTNEDELSV
CKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAIKGFDTAPLTKNY
YTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQ
ALEECSKFPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGA
SSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKTLMGQCQDL
RKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIML
SASPRMSGFMYQGKIPIAGMVVNRLDEIEGSDCMFEITGSTVERIVVHCNNNQDFQEWME
QLNRLTKGPTSCGSLSKTSSSSCSTHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLR
PSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKASEEEYVIRKSTAALEEDAQILK
VIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEV
KELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRSESSSKTSILQ
NT seq 2316 nt   +upstreamnt  +downstreamnt
atgaatccagaagaacgccttgtgacatggcttatatctttgggagttctagagtctccc
aaaaagactgtctgtgatccagaggagttcttgaagtcctcgctgaaaaatggggtagtg
ttgtgcaaactcataaacagacttctgcctggctcggtggagaagtattgtctggaaccc
caaactgaggccgactgcatcgacaacatcaatgacttcctgaaaggatgtgcaactctt
caagtggaagtgtttgagcctgatgacctctattcgggggccaatttctccaaggttctg
aatactcttttagctgtcaacaaagcaactgaagatcagctctcagaaagaccatgtgga
aggtcctcttctcttagtgctgcgaccagctctcagacaaacccgcaggtggccgttccc
agcacagctccagagcagcacagcgaggaaaaggcagagatgacggaaaatggaagtcac
cagttgatagtaaaggcaagattcaacttcaagcagacgaatgaagatgaattgtcagtg
tgtaaaggggacatcatttatgtcacacgagttgaagaaggaggctggtgggaaggcaca
ttaaatgggagaactggatggttccctagtaattatgtccgagaaattaaacccagtgag
agacctctgtcccctaaggctatcaaaggatttgacactgctccacttaccaagaattac
tacactgtggtgttacagaacatcttggacactgaaaaagaatatgccaaagaacttcag
tctcttcttgttacttacctaagacccttgcagtctaataacaacctgagtactgtggag
tttacatgtttattgggaaactttgaagaagtatgcacatttcaacagacactctgccaa
gccttggaagaatgttcaaagtttccagaaaaccaacacaaagtaggaggctgcctactg
aacctcatgcctcatttcaaatcgatgtacctggcttactgtgcaaatcatccatcagct
gtcaacgtgctcacccagcacagtgatgatctagaacgattcatggaaaatcaaggtgca
tccagcccgggtatcctcattctaacaacaagtctcagcaaaccattcatgcgactggaa
aagtatgttactctcttgcaagaactggaacgacatatggaggacactcatccagaccat
caggatattctgaaagcaatcatagcattcaaaacactcatggggcagtgtcaagatctg
agaaagagaaagcagctggaattgcagatcctttcagaacctattcaggcatgggaagga
gatgatattaagactttgggaaatgtgatctttatgtctcaagtagtgatgcagcatggg
gcctgtgaggagaaagaggaacgatattttctgctgttttcaagtgtcttgataatgttg
tctgcaagtcctcggatgagtggctttatgtatcagggaaaaataccaatagcagggatg
gtagtgaacagattggatgaaattgaaggcagtgactgtatgttcgaaatcacaggtagc
acggttgagagaattgtggtccattgcaacaataaccaggacttccaggagtggatggag
cagctgaacagactgaccaaaggaccaacctcttgcggttcattgtctaagacctcctcc
tcatcatgtagtactcattcttcttttagctctaccggacagccccgaggacccttggag
cctcctcaaattataaaaccgtggagtttaagttgcctacgacctgcacctccacttaga
ccatcagcagcactaggttataaagagaggatgtcttatatcttaaaggaatctagtaag
agccccaaaacaatgaagaagtttcttcacaaaagaaagacggagaggaaagcatccgag
gaagaatacgtgattaggaaaagtactgctgccctggaagaggatgctcagattcttaag
gtgatcgaagcttattgcaccagcgccagttttcaacaaggtactcgtaaagattctgtt
ccacaagttctactccccgaggaagagaaactcattattgaagaaaccagaagtaatggg
cagaccatcattgaagagaagagccttgttgatactgtctatgccttgaaggatgaggtc
aaggaactgaagcaggagaataaaaaaatgaagcaatgtctggaagaagaattgaagtcg
aggaaggacctagagaagctggtccggaagctgttgaaacaaacagatgaatgcattcga
tctgaatccagcagcaagacctcgattctccagtaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (17)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (32)   
   RefSeq(nuc) (14)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (13)   
   Pfam (13)   
All databases (89)   

Download RDF
DBGET integrated database retrieval system