KEGG   Mus musculus (house mouse): 75788
Entry
75788             CDS       T01002                                 
Symbol
Smurf1, 4930431E10Rik, mKIAA1625
Name
(RefSeq) SMAD specific E3 ubiquitin protein ligase 1
  KO
K04678  E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04120  Ubiquitin mediated proteolysis
mmu04137  Mitophagy - animal
mmu04144  Endocytosis
mmu04340  Hedgehog signaling pathway
mmu04350  TGF-beta signaling pathway
mmu04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    75788 (Smurf1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    75788 (Smurf1)
   04350 TGF-beta signaling pathway
    75788 (Smurf1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    75788 (Smurf1)
   04137 Mitophagy - animal
    75788 (Smurf1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    75788 (Smurf1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    75788 (Smurf1)
   04121 Ubiquitin system [BR:mmu04121]
    75788 (Smurf1)
   03029 Mitochondrial biogenesis [BR:mmu03029]
    75788 (Smurf1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     75788 (Smurf1)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    75788 (Smurf1)
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    75788 (Smurf1)
Ubiquitin system [BR:mmu04121]
 Ubiquitin ligases (E3)
  HECT type E3
   75788 (Smurf1)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    75788 (Smurf1)
SSDB
Motif
Pfam: HECT WW C2
Other DBs
NCBI-GeneID: 75788
NCBI-ProteinID: NP_001033716
MGI: 1923038
Ensembl: ENSMUSG00000038780
UniProt: Q9CUN6 Q8BSC0
Position
5:complement(144813305..144902657)
AA seq 731 aa
MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDP
KWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCK
LNPSDTDAVRGQIVVSLQTRDRIGGGGSVVDCRGLLENEGTVYEDSGPGRPLSCLMEEPA
PYTDGTGAAAGGGNCRFVESPSQDQRLLVQRLRNPEVRGPLQTPQNRPHGHQSPELPEGY
EQRTTVQGQVYFLHTQTGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVD
HNNRTTQFTDPRLHHIMNHQCQLKEPSQPLQLPSEGSVEDEELPAQRYERDLVQKLKVLR
HELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVARE
WLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYI
NGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRIL
QHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQK
ELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTR
VPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLT
AVEETCGFAVE
NT seq 2196 nt   +upstreamnt  +downstreamnt
atgtcgaaccccgggacccgtaggaacggctccagcatcaagatccgtctgacagtattg
tgtgccaagaaccttgcaaagaaagacttcttcagactccccgacccctttgccaagatt
gttgtggacggctctgggcagtgccactcaaccgacactgtgaaaaacaccctggaccca
aagtggaaccagcactatgacctgtatgttgggaaaacggactcgataaccatcagtgtg
tggaaccacaagaagatccacaagaagcagggggctggcttcctgggctgtgtgcggctg
ctctccaatgccatcagcagattgaaagacactggctaccagcgtttggatctatgcaaa
ctaaatccctcagatactgatgcagttcgtggccaaatagtggtcagtttacagacccga
gacagaataggcggtggagggtcagtggtggactgcagagggctgctggagaacgaagga
acagtgtatgaagactcaggccctggaaggccgctcagctgcctcatggaggaacctgcc
ccatatacagatggtactggtgcagcagcaggaggcgggaactgcaggtttgtggagtct
ccaagccaagatcagagactcctggtacagcgactccgaaatcctgaggttcgagggccc
ttacagacaccccagaaccgaccacatggccaccagtcgccagagctgcctgaaggctat
gagcaaaggacaacagtgcagggacaagtttactttttgcacacgcagactggagtcagt
acatggcatgaccccaggatccccagagaccttaacagtgtgaactgcgatgaacttggg
ccactgcctccaggctgggaagtccgaagcacagtgtcgggaagaatctattttgtagat
cacaataataggacaacccagtttacagatccacggcttcaccacatcatgaatcaccag
tgccaactcaaggagcccagccagccgctgcagctgcccagtgagggctccgtggaggac
gaggagcttcctgcccagagatatgagagggacttagtccagaagctcaaagttctcagg
cacgagctctctcttcagcagccccaggctggtcactgtcgaatagaagtctccagagaa
gagatatttgaggagtcgtatcgccagatcatgaagatgcggccaaaagacctaaagaag
cgcctgatggtgaagttccgaggggaggaaggtttggactatggtggagtggctcgggag
tggctgtatttgttgtgccatgaaatgttgaacccgtactatggactcttccagtattcc
acggacaatatttacacactgcagatcaacccagattcttctatcaaccctgaccatctg
tcatacttccactttgtgggtcgcatcatgggtctggctgtgttccacggacactacata
aatgggggtttcacagttccgttctacaagcagctcctggggaagccaatccagctgtcg
gacctggagtccgtggacccagaactgcataagagcttggtgtggattctagagaatgac
atcacgcctgtgttggatcataccttctgcgtggagcacaacgctttcgggcggattctc
cagcatgaactgaaacccaatggcagaaatgtgcctgtcactgaggagaacaagaaggaa
tacgtccggctgtatgtgaactggaggtttatgagaggaatcgaagcccagttcttagca
cttcagaaggggtttaacgaactcattccccaacacttgctgaagccctttgaccagaag
gaactagagctgataataggtgggctggataagatagacctgaacgactggaagtccaac
acccggctgaaacactgtgtggcagacagcaacatcgtcaggtggttctggcaggcggtg
gagaccttcgatgaggagaggagagccagactcctgcagtttgtgacaggatccacaaga
gttcctctccaaggcttcaaggctctgcaaggctctacaggcgcggcagggccccggctg
ttcaccattcacctgatagacgccaatacagacaacctgcccaaggcccatacctgcttt
aatcggatcgacatcccaccctatgagtcctatgagaagctctatgagaagctgctgaca
gcggtggaggaaacctgtggctttgcagtggagtga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (22)   
   RefSeq(nuc) (6)   
   GenBank (8)   
   EMBL (8)   
Protein domain (3)   
   Pfam (3)   
All databases (64)   

Download RDF
DBGET integrated database retrieval system