KEGG   Mus musculus (house mouse): 76089
Entry
76089             CDS       T01002                                 
Symbol
Rapgef2, 5830453M24Rik, CNRasGEF, Pdzgef1, RA-GEF-1, mKIAA0313, nRapGEP
Name
(RefSeq) Rap guanine nucleotide exchange factor (GEF) 2
  KO
K08018  Rap guanine nucleotide exchange factor 2
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04015  Rap1 signaling pathway
mmu04530  Tight junction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    76089 (Rapgef2)
   04015 Rap1 signaling pathway
    76089 (Rapgef2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    76089 (Rapgef2)
SSDB
Motif
Pfam: RasGEF RasGEF_N RA PDZ PDZ_6 cNMP_binding PDZ_2
Other DBs
NCBI-GeneID: 76089
NCBI-ProteinID: NP_001093094
MGI: 2659071
Ensembl: ENSMUSG00000062232
UniProt: E9QNQ4 Q6NXI4
Position
3:complement(78969818..79194681)
AA seq 1494 aa
MAFLVRCYANCLQPWSSKLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLSDI
YQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTDDD
IEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGSVE
VTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEKNM
QKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLLTY
RTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENNLE
REKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSCSKA
TEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEEKR
NGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKTRI
SILPQKPYNDIGIGQSQDDSIVGLRQTKHIPAALPVSGTLSSSNPDLLQSHHRILDFSTT
PDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPEQYSLCEVSVTPEGV
IKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVEVA
TQLSMRNFELFRNIEPTEYIDDLFKLKSKTSCANLKKFEEVINQETFWVASEILRETNQL
KRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDLQD
LFDPSRNMAKYRNVLSGQNLQPPVIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMIAK
EIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSANATVLDVAQTGGHKKRVRRSSFL
NAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATSTLPKNPGDKKPVKSETS
PVAPRAGPQQKVQPQQPLAQPQPPHKVSQGLQVPAVSLYPSRKKVPVKDLPPFGINSPQA
LKKILSLSEEGSLERHRKQAEDTISNASSQLSSPPTSPQSSPRKGYALALSGTVDNFSDS
GHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVESNLGVGRMERRTLMEPDQYSLG
SYAPVSESRGLYAAATVISSPSTEELSHDQGDRASLDAADSGRGSWTSCSSGSHDNIQTI
QHQRSWETLPFGHTHFDYSGDAASIWASGGHMDQMMFSDHSTKYNRQNQSRESLEQAQSR
ASWASSTGYWGEDSEGDTGTIKRRGGKDVSAEAESSSMVPVTTEEAKPVPMPAHIAVTPS
TTKGLIARKEGRYREPPPTPPGYVGIPIADFPEGPCHPARKPPDYNVALQRSRMVARPTE
APAPGQTPPAAAASRPGSKPQWHKPSDADPRLAPFQPQGFAGAEEDEDEQVSAV
NT seq 4485 nt   +upstreamnt  +downstreamnt
atggctttccttgtgcgttgctatgccaactgcctgcagccatggtcctccaaactccct
gcagacttcacaaaactgcacctcactgacagcctgcacccacaggtgacccacgtgtcc
tccagccattcaggatgtagcatcaccagcgactctgggagcagcagtctttctgacatt
taccaggccacggagagcgaggccggtgacatggacctgagtggactgccagagacggcg
gttgactctgaggatgacgatgatgaggaagacatcgagagagcatcagaccctctgatg
agcagggacatcgtgagggactgcctggagaaggacccgatagacaggactgacgatgac
atcgaacaactactggaatttatgcaccagctgccggcctttgccaatatgacgatgtca
gtaagacgggagctctgtgccgtgatggtgtttgcagtggtggaaagagctggaaccatt
gtgttaaacgacggagaagagctggattcctggtcagtgattctcaatggttccgtggag
gtgacatatccggatgggaaagcagaaattctgtgcatgggaaacagctttggtgtttcg
cccaccatggacaaagaatacatgaaaggagtcatgaggactaaggtggatgactgccag
tttgtctgcattgcccagcaagattactgccgtattttgaaccaagtagaaaagaacatg
caaaaagttgaggaggaaggagagattgtaatggtgaaggagcaccgagaacttgatcgg
actggaacaaggaagggccacatcgtcatcaagggcacctcagagaggctgaccatgcat
ttggtggaagagcattctgtagtggatccaacattcatagaagacttcctgttgacatac
cggactttcctttccagcccgatggaagtgggcaagaagttattggagtggttcaatgac
ccgagcctcagggataaggtgacgcgggtagtattactgtgggtgaataatcacttcaat
gactttgaaggggatcctgcaatgactcgatttctggaagaatttgaaaataatctggaa
agagagaaaatgggtggacatctaaggctgttgaacattgcatgtgcagctaaagccaaa
cgaagactgatgacgttaacaaagccttcccgggaagcccctctgcccttcatcttactg
ggaggctctgaaaagggctttggcatcttcgtggacagcgttgactcgtgtagcaaagcc
actgaagcaggcttgaagcgcggggatcagatattagaagtgaatggtcaaaattttgaa
aatatccaactttcaaaggcaatggaaattctcagaaataacacacacctgtccatcact
gtgaaaaccaacttatttgtatttaaagaacttctgacgagattgtctgaagagaaaaga
aacggtgcccctcacctccctaaaatcggggacatcaagaaggccagccgctactccata
ccggatctcgccgtagacgtagaacaggtgataggcctcgagaaggtcaacaagaaaagc
aaagccaacaccgtgggaggaagaaacaagctgaagaaaatactcgacaagacccggatc
agcatcttacctcagaaaccatacaatgatattgggattggtcagtctcaagatgatagc
atcgtaggactgaggcagaccaagcacatcccagctgccctgcctgtcagtggaacgctg
tcctccagtaaccctgacttgctgcagtcacaccaccggattctggacttcagcactact
cctgacttgccagatcaggtactgagagttttcaaggctgaccaacaaagcaggtacatc
atgatcagcaaggacaccaccgcaaaggaagtggtcatccaggccatcagagagtttgct
gtcactgccaccccagagcagtattccctctgtgaggtctcagtcacaccagagggagtt
atcaaacaacgccgactcccagatcagctttccaagcttgccgacaggatacaactgagt
ggaaggtattatctgaaaaacaacatggaaacagaaacgctttgctcagatgaagatgcc
caggagctgctgcgagagagccaaatctccctccttcagctcagcaccgtggaggttgcc
acgcagctctccatgaggaactttgaactcttccgcaacattgagcctactgaatacata
gatgatttatttaaactcaaatcaaaaaccagctgtgccaacctgaagaaatttgaggaa
gtcattaaccaggaaacattttgggtggcttctgaaatcctgcgggaaacaaaccagctg
aagaggatgaagatcattaagcatttcatcaagattgccttgcactgcagggaatgcaag
aattttaactccatgtttgcaatcatcagtggcctaaacctggcaccggtggcaagacta
cgaaccacctgggaaaagcttcccaataaatatgaaaagctgttccaggacctgcaagac
ctgtttgatccttccagaaacatggcaaagtaccgcaatgtcctgagtggccagaactta
cagcctcctgtcattcccctgttccctgtcatcaagaaggacctcacgtttctccatgag
ggaaatgactcaaaagtagacggactggtcaactttgagaagctgaggatgattgcaaaa
gaaatccgtcacgttggccgaatggcatcagtcaacatggaccctgcccttatgttcagg
actcggaagaagaagtggcggagtctggggtccctgagtcagggcagtgcaaacgccaca
gtgctggatgttgctcagacaggcgggcataaaaagcgggtacgccgtagttccttcctc
aatgccaaaaagctgtatgaagatgcccagatggctcggaaagtgaagcaatacctgtcc
aacctggagctggagatggatgaggagagtcttcagacactgtcactgcagtgtgaacca
gcaaccagcacattgcccaagaatcctggagacaaaaagcctgtcaagtctgagacctcc
ccagtggctccacgtgcagggccccagcagaaagtacagcctcagcagccgctggcacag
ccacaacctccacataaagtcagccagggactgcaggtgcccgctgtgtccctctatcct
tcacgaaagaaggtgccggtgaaggatctgcctccttttggcataaactctccacaagct
ttgaagaaaatcctgtccttgtctgaagaagggagtttggagcgtcacaggaagcaagca
gaagatacaatatcaaatgcgtcctctcagctctcatcgccccccacctcacctcagagc
tctccaaggaaaggttatgcactggctctcagtggcaccgtggataatttctcagattca
ggtcacagtgagatttcttcacgatccagtattgtcagcaattcttcttttgactcggtg
ccagtctctctgcatgatgaacggcgccagaggcattctgtcagcattgtggagagcaac
ctaggtgtgggcaggatggagcggcggaccctgatggagcctgatcaatacagcttaggg
tcgtatgccccagtgtctgaaagccgaggcctgtatgccgcagcgacggtcatctcttct
cctagcacagaggagctttcccatgaccaaggggaccgtgcttccctcgatgctgctgac
agcggtcgtgggagctggacatcatgctcaagtggttcccatgacaacatacagaccatt
cagcaccagagaagctgggaaacactgccatttgggcacactcactttgactattcaggg
gatgctgcaagtatatgggcctccggtggccatatggaccaaatgatgttttctgatcat
agcacaaaatataacagacagaatcaaagtagagagagtcttgaacaagcccaatcccgg
gccagctgggcgtcttccacgggctactggggagaagactcagaaggcgacacaggcact
atcaagcgaaggggtgggaaggatgtctccgctgaggcagagagcagcagcatggtgccc
gtgactacagaggaagccaaacctgtccctatgcctgcccacatagctgtgacgccgagc
actaccaagggactcatcgcacggaaggaaggcaggtaccgggagccgcctcccacacct
ccaggctacgtgggcatccccattgccgatttcccagaagggccttgccacccggccagg
aagcccccggattacaacgtggccctgcagcggtcccgcatggtggcacggcccactgag
gccccggcaccgggccagacgccgcctgcagccgcagccagccggccgggcagcaagcca
cagtggcacaagcccagcgacgcagacccacgcctcgcgcccttccagccgcagggcttc
gcaggagcggaggaggacgaagatgaacaagtgtctgctgtttga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (11)   
   UniProt (2)   
   RefSeq(pep) (9)   
DNA sequence (25)   
   RefSeq(nuc) (9)   
   GenBank (8)   
   EMBL (8)   
Protein domain (7)   
   Pfam (7)   
All databases (68)   

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