KEGG   Mus musculus (house mouse): 78925
Entry
78925             CDS       T01002                                 
Symbol
Srd5a1, 0610031P22Rik, 4930435F02Rik, S5AR_1, Srd5a-1
Name
(RefSeq) steroid 5 alpha-reductase 1
  KO
K12343  3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00140  Steroid hormone biosynthesis
mmu01100  Metabolic pathways
Module
mmu_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
mmu_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    78925 (Srd5a1)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     78925 (Srd5a1)
SSDB
Motif
Pfam: Steroid_dh DUF1295 PEMT
Other DBs
NCBI-GeneID: 78925
NCBI-ProteinID: NP_780492
MGI: 98400
Ensembl: ENSMUSG00000021594
UniProt: Q68FF9 A0A0R4J136
Position
13:complement(69721568..69759611)
AA seq 255 aa
MELDELRLLDALVYLEGFLAFVAFVGLQMVGSSYGRYSSQWSGRRVPARPAWFLQELPSM
AWPLYECIRPAAARLGNLPNRVLLAMFLIHYVQRTLVFPVLIRGGKPTLLFTFVLAFLFC
TLNGYLQSRYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYK
IPRGGLFEYVSSANYFGELVEWCGFALASWSLQGVVFALFTLCALFTRARQHHQWYLEKF
EDYPKTRKILIPFLL
NT seq 768 nt   +upstreamnt  +downstreamnt
atggagttggatgagttgcgcctactggatgcgctagtctacctggagggtttcctggct
ttcgtggccttcgtggggctccagatggtgggctcttcctacggccgctactcctcgcag
tggtccggccgccgagtgcccgcgcgacctgcctggttcctacaggagctgccttcaatg
gcctggccgctgtacgagtgcatccgtcctgcagccgcccgactgggcaacctgcctaac
cgcgtcctgctagctatgtttctgatccactacgtgcaaaggacgctggtttttccagtt
ctgatcaggggagggaagcccaccctgctgttcacctttgtcttggccttcctgttctgc
accttaaatggctacttgcagagccgatacttgagccagtttgcggtgtatgctgaagac
tgggtaacccatccctgtttcctgacaggctttgccctgtggttagtgggcatggtgata
aatatccactcagaccacatcctgcggaatctgagaaaaccaggggaaactggatacaaa
atacccaggggaggcctgtttgaatatgtatcttcagccaactattttggggagctcgtg
gagtggtgtggctttgcactggccagctggtccctccagggcgtggtgtttgctctgttc
accctgtgtgcactgttcaccagagcgaggcagcatcatcagtggtacctcgagaagttt
gaagattaccccaaaacaagaaaaatactaattccattcctgctttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (2)   
   KEGG MODULE (2)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (15)   
   RefSeq(nuc) (3)   
   GenBank (6)   
   EMBL (6)   
Protein domain (3)   
   Pfam (3)   
All databases (72)   

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