KEGG   Mus musculus (house mouse): 84505
Entry
84505             CDS       T01002                                 
Symbol
Setdb1, ESET, KMT1E, mKIAA0067
Name
(RefSeq) SET domain, bifurcated 1
  KO
K11421  [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00310  Lysine degradation
mmu01100  Metabolic pathways
mmu04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    84505 (Setdb1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    84505 (Setdb1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    84505 (Setdb1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.366  [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase
     84505 (Setdb1)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     84505 (Setdb1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    84505 (Setdb1)
SSDB
Motif
Pfam: DUF5604 Tudor_4 MBD SET Tudor_5 Pre-SET DUF4537 53-BP1_Tudor
Other DBs
NCBI-GeneID: 84505
NCBI-ProteinID: NP_001157113
MGI: 1934229
Ensembl: ENSMUSG00000015697
UniProt: D3YYC3
Position
3:complement(95230836..95264513)
AA seq 1308 aa
MSSLPGCMSLAAAPAAADSAEIAELQQAVVEELGISMEELRQYIDEELEKMDCIQQRKKQ
LAELETWVLQKESEVAYVDRLFDDASREVTNCESLVKDFYSKLGLQYHDSSSEDEASRPT
EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
HKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGKKYKVKFDNKGKS
LLSGNHIAYDYHPPADKLFVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
YASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEG
TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTR
PNMGAVRSKGPVVQYTQDLTGTGIQFKPMEPLQPIAPPAPLPIPPLSPQAADTESLESQL
AQSRKQVAKKSTSFRPGSVGSGHSSPTSSTLSENVSAGKLGINQTYRSPLASVTSTPASA
APPVPPVPPGPPTPPGPPAPPGPLAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTC
LSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIE
RYLFETGCDFLFLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPP
PQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPN
SGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDD
IAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPTSSDSSG
VDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENELSEM
TSKDSRPPDLGPPHVPIPSSVSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRS
SFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDNKQPKKEDPENRNKMPVVTEGSQNHG
HNPPMKSEGLRRSASKMSVLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTAGHT
SATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMA
SVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLR
FPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
NT seq 3927 nt   +upstreamnt  +downstreamnt
atgtcctccctccctgggtgcatgagtttggctgcagcgccagctgcagctgactctgca
gagattgctgagctgcagcaggcggtggttgaagagctgggtatctctatggaggaactt
cgtcagtacattgatgaggaactggaaaagatggactgcatacagcagcgcaagaagcag
ctcgcagagctggagacgtgggtactacagaaagagtctgaagtggcttatgttgatcgg
ctgtttgatgatgcatccagggaagtgactaactgtgagtctttggtgaaggatttctac
tctaagctgggactacagtatcatgacagtagctctgaggatgaagcttcccggcccaca
gagatcattgagattcctgatgaagatgatgatgtcctcagtattgattcaggtgatgct
gggagcagaactccaaaagaccagaagcttcgtgaagctatggctgccttaagaaaatca
gctcaagatgtccagaagttcatggatgctgtcaacaagaaaagcagttctcaagatcta
cataaaggaaccttgggtcaggtgtctggagaactgagcaaagatggggacctgatagtc
agcatgcggattctgggcaagaagaggactaagacatggcacaaaggcacccttattgcc
atccagactgttgggctaggaaaaaaatacaaagtgaaatttgacaacaaaggaaagagt
ctgctatctgggaaccatattgcctatgattaccaccctcccgctgacaagctgtttgtg
ggcagtcgagtggtggccaagtacaaagatggaaatcaggtctggctttatgctggcatt
gtagctgagacccctaacgtcaagaacaagctcagatttttaattttttttgatgatggc
tatgcttcctatgtcactcagtcagagctttatcccatttgccgaccactaaaaaagact
tgggaggacatagaagatagctcctgccgagacttcatagaggaatatatcactgcctat
ccaaaccgcccaatggtacttctcaagagtgggcagcttatcaagactgagtgggaaggc
acatggtggaagtctcgagttgaagaggtggatggcagcctagtcaggatcctctttctg
gatgacaaaagatgtgagtggatatatcgaggctctacacgcctggaacctatgtttagt
atgaagacatcctcagcctctgcaatggagaagaagcaaggggggcaactcagaacccgt
cctaatatgggtgctgtgaggagcaaaggtcctgttgttcagtatacacaggatctaact
ggtactggaatccagtttaagcccatggagcccctacagcctatagctccaccggcccca
cttcctatacctcctctttccccccaagcagctgacactgaaagcttagaaagccaactt
gcacaatcacggaaacaagtagccaagaagagcacatcattccgaccaggatctgtgggc
tccggccattcctcccctacttcatccacactcagtgaaaatgtgtctgctgggaaactt
gggataaaccagacatatcggtcacctttggcctcagtaacatctaccccagcatctgca
gcccctccagtccctccagtcccaccagggcctccaacccctccagggcctccagctcct
ccagggcctctagctcctccagccttccatggcatgttagagcgggcaccagctgagccc
tcctaccgagcccccatggagaagcttttctatttacctcatgtctgcagttacacttgt
ttgtcccggatcagacccatgagaaacgaacagtatcggggcaagaaccctctattagtt
ccacttctgtatgacttccggaggatgacagcacggcgcagagttaaccgcaaaatgggc
tttcatgtaatctataagacaccctgtggtctctgccttcggacgatgcaggagatagag
cgctacctttttgagactggctgtgactttctgttcctggagatgttctgtttggatcca
tatgttcttgttgacagaaagtttcaaccctttaagcctttttactatattttggacatc
acctatggcaaggaagatgttcccctgtcctgtgttaatgagattgacacaactccccca
ccccaggtggcctacagcaaggaacgcattcctggcaagggtgttttcattaacacaggc
cctgaatttctggttggctgtgactgcaaggatgggtgtcgggataaatccaaatgtgcc
tgccaccagctaactatccaggccacagcctgtaccccagggggccaagtcaaccctaac
tctggctaccagtataaaagactagaagagtgtctgcccacaggggtttatgagtgtaac
aaacgctgcaattgtgacccaaacatgtgcacaaatcggttggtgcagcatggtctgcag
gttcgactacagctgtttaagacacagaacaagggctggggtatccgctgcttggatgat
attgccaaaggctcttttgtctgcatttatgcaggcaaaatcctgacagatgactttgca
gacaaagaaggcctggagatgggtgatgagtactttgcaaatctggaccacattgaaagt
gtggagaacttcaaggaaggatatgagagtgatgtccccacttcctctgacagcagtggg
gtagatatgaaggaccaggaagatggcaacagcggttcagaggaccctgaagaatccaat
gatgacagctctgatgataacttctgtaaggatgaggacttcagcaccagttcagtgtgg
cgtagctatgctacccggaggcagactcggggtcaaaaggagaatgaattgtctgagatg
acttccaaggactcccgccccccagacctcgggcctccacatgttcctatcccttcctca
gtatctgtagggggctgcaatccaccttcctctgaagagacacccaagaacaaggtggcc
tcgtggttgagttgcaatagtgtcagtgaaggtggatttgctgactctgacagccgttct
tccttcaagactagtgaaggtggagatggccgtgctgggggaggccggggagaggctgaa
agggcctctacctcaggattgagcttcaaggatgaaggagacaataagcagcctaaaaaa
gaggaccctgagaaccgaaacaagatgccagtagttactgaaggctctcagaatcatgga
cataatcctcccatgaagtctgaagggcttcgccgatcagctagtaaaatgtctgtgctc
cagagccagcgagttgtgacttctactcagtcaaaccctgatgacatcctgacactgtcc
agcagcacagagagtgagggggaaagtggaaccagccgaaagcccactgctggtcacact
tcagccacagctgttgatagtgatgacatccagaccatctcttctggctctgacggtgat
gactttgaggacaagaagaacttgtcaggaccaacaaagcgccaggtggcagtaaaatca
acccgaggctttgctcttaaatcaacccatggtattgccattaaatcaaccaacatggct
tccgtggacaagggggagagtgcaccagttcgtaagaacacacgccagttctatgatggt
gaagagtcttgctacatcattgatgccaaacttgaaggcaacctaggccgctacctcaat
cacagttgcagccccaacctgtttgtccagaatgtgtttgtggatacccatgatcttcgc
ttcccttgggtggccttctttgccagcaagagaatccgggctggaacagaactcacttgg
gactacaactacgaagtgggcagtgtggaaggcaaggagctgctgtgctgctgtggggcc
attgaatgcagagggagacttctttag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (39)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (30)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (32)   
   RefSeq(nuc) (4)   
   GenBank (14)   
   EMBL (14)   
Protein domain (8)   
   Pfam (8)   
All databases (97)   

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