KEGG   Mus musculus (house mouse): 98432
Entry
98432             CDS       T01002                                 
Symbol
Phlpp1, Phlpp, Plekhe1, SCOP, mKIAA0606
Name
(RefSeq) PH domain and leucine rich repeat protein phosphatase 1
  KO
K16340  PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04151  PI3K-Akt signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    98432 (Phlpp1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    98432 (Phlpp1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     98432 (Phlpp1)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Mg2+- or Mn2+- dependent protein phosphatases (PPMs)
   PPM1 phosphatases (PP2C)
    98432 (Phlpp1)
SSDB
Motif
Pfam: LRR_8 PP2C LRR_4 LRR_1 LRR_6 PH
Other DBs
NCBI-GeneID: 98432
NCBI-ProteinID: NP_598582
MGI: 2138327
Ensembl: ENSMUSG00000044340
UniProt: Q8CHE4
Position
1:106099599..106321975
AA seq 1687 aa
MEPAAAAPAQRLADPTGEDQALAAAAAEGGRCPDPALSAAAPSGGNGGAAREEAPCEAPP
GPLPGRAGGTGRRRRRGAPQPAAGGAAPVPAAGGGANSLLLKRGRLKRNLSAAAAASSSS
SPSSASSAAGGLPASCSASASLCTRSLDRKTLLLKHRQLLQLQPSDRDWVRHQLQRGCVH
VFDRHMASSYLRPVLCTLDTTAAEVAARLLQLGHKGGGVVKVLGYGPPPAAAPAASDQTL
DGEHGRDVEPPPSSGTVGAVRGPARAPPADLPLPGGAWTRCAPRISPAPSDSSPGELFAG
GPGSPPRAPRPASDTESFSLSPSAESVSDRLDPYSSGGGGSSSSSEELEADPAMPHRPGR
PAQPRPPSPKTSALLQPKAPTGVDSTGVIAGEGPGDDKAMAAAAPDVPLSTSGRIRETVQ
KTSPPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFY
AGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRWTRRQVILCGTCLIVSSVKDSVSGKMHV
LPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDL
SCCSLEHLPANLFYSQDLTHLNLKQNFLRQTPTLPAARGLGELQRFTKLKSLNLSNNHLG
AFPSAVCSIPTLAELNVSCNALREVPAAVGDMQNLQTFLLDGNFLQSLPAELESMHQLSY
LGLSFNEFTDIPEVLEKLTAVDKLCMAGNCVETLRLQALRRMPHIKHVDLRLNILRKLMA
DEVDFVQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLNVCGYFLKALYASSNEL
AQLDVYPVPNYLSYMDVSRNCLESVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRK
LLAGHNRLARLPERLERTSVEVLDVQHNQITELPPNLLMKADSLRFLNASANKLETLPPA
TLSEETSSILQELYLTNNCLTDKCVPLLTGHPRLKILHMAYNRLQSFPASKMAKLEELEE
IDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLSCNELSEITLPE
NLPPKLQELDLTGNPRLALDHKSLELLNNIRCFKIDQPSAGDASGAPAVWSHGYTEASGV
KNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMV
NTFIVMQRKLGTAGQKLGGAAVLCHIKPDPVDLGGSFTLTSANVGKCQTVLCRNGKPLSL
SRSYIMSCEEERKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTP
QDEFFILGSKGLWDSLSIDEAVEAVRNVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSV
TEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDGLGVPSSSSGMASEISSELSTS
EMSSEVGSTASDEPPSGVLNESSPAYPNEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNG
LDSDDEEPIEGVFSNGSRVEVEVDIHCSRAKEKERQQHLLQVPAEASDEGIVISANEDES
GLSKKADFSAVGTIGRRRANGSVAPQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQF
IIPPELEEEVKEIMKHHQEQQQQQQQQQLPPPPQPPQPQPQPQPQPQPQPQRHFQMDHLP
DCYDTPL
NT seq 5064 nt   +upstreamnt  +downstreamnt
atggagcccgccgctgcagccccggcacagcgactcgcggaccccacgggtgaggaccaa
gccctggcggcggcggcggccgagggcggccggtgtccggatcccgcgctgagcgcggcg
gccccgagcggcgggaacggcggcgcggcgcgagaggaggccccctgcgaggcgccgccg
gggccgctgcccggccgcgccggaggcaccgggcgcaggcggcggcggggagctccccag
cccgcggccggtggggccgctccggtgcccgcggccggcggcggcgccaactcgctgctg
ctgaagagagggcggctgaagaggaatctgtcggccgccgccgccgcctcgtcgtcctcg
tcgccgtcctcggcgtcttcggccgctggcggcctcccggcgtcctgctcggcctcggcg
tcgctgtgcacccggagcctggacaggaagacgctgctcctgaagcaccggcagctgctt
cagctgcagccgtcggacagggactgggtgaggcaccagctccagcggggctgtgtgcac
gtctttgaccgccacatggcctcgtcctacctgcgcccagtgctctgcacgctggacacc
acggccgccgaggtggcggcccggcttctgcagctgggccacaaaggcggcggggtggtg
aaggtgctgggctacgggccgcctcccgccgccgcccctgccgccagcgatcagaccctg
gacggagagcacggaagggacgtggagccaccgccctcgagcggcactgttggtgctgtc
cggggccctgcgcgcgcgcctcccgccgatctgccgctgcccgggggcgcctggacgcgc
tgtgcaccccgcatcagccccgcgccttcggactccagccccggagagctgttcgcgggc
ggccccgggtcccctccccgcgccccgcgcccggcctctgacaccgagagcttcagcctg
agccccagcgccgagagcgtgtcagaccggctggacccctacagcagcggcggcggcggc
tcctcgtcgtcgtcggaggagttagaggctgatccggccatgccccaccgccccggccgc
cccgcgcagcctcggccgccttccccgaagacctcggctttactgcagccgaaagccccg
acgggcgtagacagcactggcgtgatagcgggcgagggtcccggagacgataaggcgatg
gcagccgcagctccggacgttcctctgtcgacttcggggaggatacgggagaccgtgcaa
aagacatctccgccctccctgtatgtacagctccatggagagactacccggcgcctggag
gcggacgagaagccattgcagatccaaaatgactacctcttccaactgggatttggggag
ctgtggagggtgcaggaggaaggcatggactcagagattggctgtctcattcgattctat
gcaggaaagcctcatagcactgggagctctgagcggattcagctctccggaatgtacaat
gtccgaaaaggcaaaatgcagttgccagtgaaccgatggacaagacgacaggtcattctg
tgcgggacgtgcttgatagtgtcgtccgtgaaagacagcgtgagtgggaagatgcatgtc
ctgcccctcattggtggaaaagtggaggaagtgaaaaagcaccagcactgtttagcgttc
agctcttcggggcctcaaagccagacttactacatctgctttgatactttcacggagtac
ttacggtggctgcggcaagtctccaaggttgcatcacagcgtataagctcagtagacctc
tcctgttgtagccttgaacatctgcctgccaacctcttttacagccaagaccttactcat
ctcaacttaaaacagaacttcctaaggcaaacccccaccctcccagctgccagaggactt
ggtgaactgcaaaggttcaccaaattgaagagccttaacctttccaataaccacctagga
gcctttccgtcagcagtctgcagcattccaaccctagcagagctgaatgtatcttgcaat
gccctgcgagaagtcccagcagctgttggagatatgcagaacttgcagacgtttctgctg
gatggaaattttctccagtcccttcctgctgaactggagagcatgcaccagctcagctat
ctgggtctttcctttaatgaattcactgacattccagaggtattggagaagctgactgct
gtggataagctgtgtatggctgggaactgtgtggagaccctcagactacaggccttaaga
agaatgcctcatattaaacatgtggacctaagactgaacatactcagaaagcttatggca
gatgaggtggactttgtgcaacatgtcactcagcttgacctgcgagacaataagcttggt
gatctagatgctatgatcttcaacaacatagaagttctgcactgtgagaggaatcagctg
gtgacattgaacgtttgtggctatttcctaaaggcactctatgcttcttctaatgaactt
gctcaacttgatgtctacccagttccgaattatctctcttacatggatgtctcaagaaac
tgcctagaaagtgtgcctgagtgggtatgtgaaagccggaaattagaagttttggatatt
ggccataatcaaatatgtgaacttcctgcccgcctgttttgtaatagtagtctccggaaa
ttgctagcaggacacaaccggttggcaaggcttcctgaaaggctggagagaacttctgtg
gaggtcttggatgtccagcacaaccagatcactgagctcccaccaaacctcctcatgaag
gctgacagcctgagattcctgaatgcatctgcaaacaaactggaaaccctgcctccagcc
acactttctgaggagacgagcagtatattacaggagttgtacctgacaaacaactgcctc
acggataagtgtgtgcccttgttaacagggcacccccgtctgaagatcctacacatggcc
tataaccggcttcagagcttcccggcaagtaaaatggcaaaactggaggaacttgaagaa
attgatatcagtgggaataagctgaaagccatccccacaacaatcatgaactgcagacgc
atgcacaccgtgattgctcactccaattgtatcgaagtctttcctgaagttatgcagctc
ccagaagtcaagtgtgtagatctgagctgtaatgagctgagtgaaatcacgttaccagaa
aacctgccacctaagctgcaggagctagacctgactggaaatccacgccttgccctggac
cacaaaagcctggagctgctcaataacattcgctgcttcaagattgaccagccgtcagca
ggagatgcatcaggagccccagcagtatggagtcatggttacactgaagcatcgggagta
aaaaacaagctgtgtgtcgcagccctgtctgtaaataacttccgtgacaaccgagaggcc
ctctatggtgtgtttgatggagaccggaatgtggaggtgccctaccttctccagtgcacc
atgagtgacattttggctgaagagcttcagaaaacgaaaaatgaagaagaatacatggtc
aatacattcatagtcatgcaaaggaaactgggaactgctgggcagaaacttggtggtgct
gctgtcctctgccacatcaagcctgaccctgtggacctgggaggatcctttaccctgacc
tctgctaatgttggcaagtgccaaacggttctctgtcgaaatgggaagccactgtctctg
tccaggtcatacatcatgagctgtgaagaagagcggaagaggattaagcagcacaaagcc
atcatcactgaggatggcaaggtcaatggagtgacagagtccacgcgcatcctgggctac
accttcctccatcccagtgtggtgcctcgcccccatgtgcagtcggtgcttctgactcca
caggatgagtttttcatcctgggcagcaaagggctgtgggacagcctatccattgacgag
gctgtggaagctgtacgcaatgtgccagatgctctggctgctgctaagaagctctgcacc
ctggctcagagctatggctgccatgacagcatcagtgctgtggtggtacagctaagtgtc
accgaagacagcttctgctgctgtgagctcagtgctggagggagcatgccaccacccagc
cccggaatcttcccaccatccgtcaacatggtcatcaaggaccgaccctcagatgggctg
ggtgtgccatcctccagcagtggcatggcatctgagatcagcagtgaactgtctacctcc
gagatgagtagtgaggtgggctccacagcctctgatgagcccccgtctggagtcctgaat
gagagcagccctgcctaccccaacgagcagcgctgcatgctccaccctgtctgcctgtct
aactccttccaacgtcagctgtccagcgctactttctccagcgcgttctctgacaacggc
cttgacagtgacgatgaagaacccattgagggggtgttcagcaacggcagccgggttgag
gtggaagtagacatccactgcagcagggccaaggaaaaggagagacagcagcacctactt
caggtgccagctgaggccagtgatgagggcattgtcatcagtgccaatgaggatgagtca
ggtctgtccaagaaggcagacttttctgctgtgggaaccattggacgacgcagggctaat
ggctctgtagctccccaggaaaggagccataatgtgatagaggttgctgcagatgcgcct
ctccggaagccaggaggctattttgcagcccctgctcagccagatccagatgatcagttt
atcatccccccagagctggaagaggaagtcaaagaaatcatgaaacatcaccaggagcag
cagcagcagcagcagcagcagcagctgccaccaccaccccagccgccacagccacagcca
cagccacagccacagccacagccacagccacagcggcacttccaaatggatcacctgcca
gactgttacgatacaccgctatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (70)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (63)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (6)   
   Pfam (6)   
All databases (102)   

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