KEGG   Mus musculus (house mouse): 99982
Entry
99982             CDS       T01002                                 
Symbol
Kdm1a, 1810043O07Rik, Aof2, D4Ertd478e, Kdm1, Lsd1, mKIAA0601
Name
(RefSeq) lysine (K)-specific demethylase 1A
  KO
K11450  [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04714  Thermogenesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    99982 (Kdm1a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    99982 (Kdm1a)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.66  [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase
     99982 (Kdm1a)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HDAC complexes
    BRAF-HDAC complex
     99982 (Kdm1a)
    REST complex
     99982 (Kdm1a)
   Histone demethylases
    99982 (Kdm1a)
SSDB
Motif
Pfam: Amino_oxidase SWIRM NAD_binding_8 DAO Pyr_redox_2 AlaDh_PNT_C Pyr_redox FAD_binding_2 FAD_oxidored HI0933_like FAD_binding_3 Thi4 GIDA MutS_IV Sec10_N 2-Hacid_dh_C Lycopene_cycl Pyr_redox_3
Other DBs
NCBI-GeneID: 99982
NCBI-ProteinID: NP_598633
MGI: 1196256
Ensembl: ENSMUSG00000036940
UniProt: Q6ZQ88
Position
4:complement(136277844..136330127)
AA seq 853 aa
MLSGKKAAAAAAAAAAAAAAGTEAGSGAAGGAENGSEVAAPPAGLTGPTDMATGAAGERT
PRKKEPPRASPPGGLAEPPGSAGPQAGPTAGPGSATPMETGIAETPEGRRTSRRKRAKVE
YREMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAF
QSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLE
APYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPIKKTGKVIIIGSGVSGLAAARQLQS
FGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQK
CPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQ
EKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFL
VKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFA
NATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASG
CEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNL
NKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENIS
DDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQP
ITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQ
ATPGVPAQQSPSM
NT seq 2562 nt   +upstreamnt  +downstreamnt
atgttgtctgggaagaaggcggcggcggcggcagcggcagcggcggcggcggcggctgct
gggaccgaggccgggtccggggcggcgggcggtgccgagaacggctctgaggtggccgcg
ccgcccgcgggcctgacgggccccaccgacatggctacgggggcggcgggcgagcgcact
ccccgaaagaaggagcctccgcgggcctcgccgcccgggggcctagccgagccgccgggg
tctgctgggccccaggcggggcccacagccgggcccggctccgcgacgcccatggagacc
ggaatagccgagaccccggagggccgacggaccagccggcgcaagcgggccaaggtagaa
tacagagaaatggatgaaagcttggccaacctctcagaagatgaatattattcggaagaa
gaaagaaatgctaaagcagagaaggaaaagaagcttcccccaccacctcctcaagcccca
cctgaggaagaaaatgaaagtgagccggaagagccgtctggtgtggagggtgcagctttt
caaagccgacttccccatgaccgaatgacctctcaggaagcagcctgtttcccagacatc
atcagtgggcctcagcagacacagaaggtttttctgttcatcaggaatcgcacattgcag
ttatggctggacaacccaaagatccagctgacgtttgaagccactctccagcagctggaa
gcgccttacaacagcgatactgtgcttgtccaccgagttcacagttacttagagcgccat
ggtcttatcaacttcggcatctacaagaggataaaacccttaccaattaaaaagacagga
aaggtgattattataggttcaggtgtttctggcttggcagcagctcgacagctacagagt
tttgggatggatgtcacacttctggaagccagggatcgagtaggtggacgagttgctaca
tttcgaaaaggaaactatgtagctgatcttggcgccatggttgtaacaggtcttggaggg
aatcccatggctgtcgtcagcaaacaagtaaatatggaactggccaagatcaagcaaaaa
tgcccactttatgaagccaatggacaagctgttccaaaagaaaaagatgaaatggtagaa
caagaatttaaccggttgctagaagccacttcttaccttagtcaccagttagacttcaac
gtcctcaataataaacctgtatcccttggccaggcattggaggttgtcattcagctgcaa
gaaaagcatgtcaaagatgagcagattgaacattggaagaagatagtgaaaactcaggag
gagttgaaagagcttcttaataagatggtaaatttgaaggagaaaattaaagagctccat
cagcaatacaaagaagcttcagaagtgaagccgcccagagatatcacagccgagttcctg
gtgaagagcaagcacagggacctgactgccctctgcaaggaatatgatgaattagctgaa
acacaaggaaagctagaagaaaaacttcaagaattggaagccaatcccccaagtgatgta
tacctctcatcaagagacagacaaatacttgactggcattttgcaaatcttgaatttgcc
aacgccacacctctctctaccctctctcttaaacattgggatcaggatgatgactttgag
tttactggaagccacctgacagtaaggaatggctactcatgtgtgcctgtggctttagct
gaaggcttggacattaaactgaacacagcagtgcggcaggttcgctacacagcctcagga
tgtgaagtgattgctgtgaacacacgttccacaagtcaaacctttatttataagtgtgat
gcagttctctgtacacttcctttgggagtgttgaagcagcagccaccagctgttcagttt
gtgccacctcttcctgagtggaaaacatctgcagtccaaaggatgggatttggcaacctt
aacaaggtggtgttatgctttgaccgtgtgttctgggacccaagtgtcaatttgtttggg
cacgttggcagtacaactgctagcaggggtgagctcttcctcttctggaacctatataaa
gctccaatactattggccctggtagcaggagaagctgctggcattatggagaacattagt
gatgatgtgattgtcggccggtgcctggccattctcaaagggatttttggcagcagtgca
gtcccacagcccaaggaaactgtggtatctcgttggcgtgctgatccgtgggcccggggc
tcctattcttatgtggctgcaggatcctctggaaatgactatgatttaatggctcagccg
atcactcctggcccctcaattccaggtgccccacagccaatcccaagactcttctttgct
ggagaacacacaatccggaactacccagctacagtccatggtgctctgttgagtgggctt
cgagaagcaggaaggattgccgaccagtttttgggagccatgtacactttgcctcgtcag
gccacaccaggtgtccctgcacagcagtccccaagtatgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   NAGAHAMA-S (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (18)   
   RefSeq(nuc) (4)   
   GenBank (7)   
   EMBL (7)   
Protein domain (18)   
   Pfam (18)   
All databases (74)   

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