KEGG T00015: Rv0234c

Mycobacterium tuberculosis H37Rv: Rv0234c

Entry

Rv0234c           CDS       T00015

Symbol

gabD1

Name

(RefSeq) succinate-semialdehyde dehydrogenase

K00135

succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]

Organism

mtu Mycobacterium tuberculosis H37Rv

Pathway

mtu00250

Alanine, aspartate and glutamate metabolism

mtu00310

Lysine degradation

mtu00350

Tyrosine metabolism

mtu00650

Butanoate metabolism

mtu00760

Nicotinate and nicotinamide metabolism

mtu01100

Metabolic pathways

mtu01120

Microbial metabolism in diverse environments

Module

mtu_M00027

GABA (gamma-Aminobutyrate) shunt

Brite

KEGG Orthology (KO) [BR:mtu00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    Rv0234c (gabD1)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    Rv0234c (gabD1)
   00310 Lysine degradation
    Rv0234c (gabD1)
   00350 Tyrosine metabolism
    Rv0234c (gabD1)
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    Rv0234c (gabD1)
Enzymes [BR:mtu01000]
1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.16  succinate-semialdehyde dehydrogenase [NAD(P)+]
     Rv0234c (gabD1)
    1.2.1.20  glutarate-semialdehyde dehydrogenase
     Rv0234c (gabD1)
    1.2.1.79  succinate-semialdehyde dehydrogenase (NADP+)
     Rv0234c (gabD1)

SSDB

Motif

Pfam:

Aldedh LuxC fvmX5 Acetyltransf_6

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

TubercuList:

UniProt:

Position

complement(279605..281140)

AA seq 511 aa
MRSVTCSATLVLPVIEPTPADRRPRHLLLGSAGHVSGRLDTGRFVQTHPAKDVSVPIATI
NPATGETVKTFTAATDDEVDAAIARAHRRFADYRQTSFAQRARWANATADLLEAEADQAA
AMMTLEMGKTLAAAKAEALKCAKGFRYYAENAEALLADEPADAAKVGASAAYGRYQPLGV
ILAVMPWNFPLWQAVRFAAPALMAGNVGLLKHASNVPQCALYLADVIARGGFPDGCFQTL
LVSSGAVEAILRDPRVAAATLTGSEPAGQSVGAIAGNEIKPTVLELGGSDPFIVMPSADL
DAAVSTAVTGRVQNNGQSCIAAKRFIVHADIYDDFVDKFVARMAALRVGDPTDPDTDVGP
LATEQGRNEVAKQVEDAAAAGAVIRCGGKRLDRPGWFYPPTVITDISKDMALYTEEVFGP
VASVFRAANIDEAVEIANATTFGLGSNAWTRDETEQRRFIDDIVAGQVFINGMTVSYPEL
PFGGVKRSGYGRELSAHGIREFCNIKTVWIA

NT seq 1536 nt +upstreamnt +downstreamnt
atgcgatcggtgacatgttccgccacgctggtcctgcccgtgatagagcccaccccagcc
gataggaggccccgacacctcctgctcgggagcgctggccacgttagtggcaggctggac
accggacgatttgtgcaaacccacccagcaaaggatgtcagcgtgcccatcgccaccatc
aacccggctaccggcgaaacagtcaagacattcactgcggcgaccgatgacgaagtcgac
gcggcaatagcccgggcccaccggcggttcgccgactaccgccagaccagcttcgcccag
cgcgcccggtgggccaatgccaccgccgacttgctggaagccgaggccgaccaggccgcc
gcgatgatgacgctcgagatgggcaagacgctggccgcggccaaagccgaggcactgaag
tgcgccaagggttttcgctactacgccgaaaacgccgaggcgttgctggccgacgaaccc
gccgatgcggccaaggtcggggcgtcggcggcctacggccgataccagccgctcggggtg
atcctggcggtgatgccatggaacttccccctgtggcaagcggttcggttcgccgcaccg
gcactgatggccggaaacgtcggcctgctcaagcacgcgtcgaacgtgccgcaatgcgcg
ctgtacctggccgacgtcatcgcccgaggcggcttcccggacggctgcttccagacgttg
cttgttagctcgggagccgtcgaagccatcctgcgtgatccccgggtcgcggcggccacg
ctgaccggaagcgagccggccggccaatcggtgggcgctatcgccggtaacgagatcaag
ccgaccgtgctcgagctcggcggcagcgacccgttcatcgttatgccgtcggccgatctg
gacgccgcggtcagcaccgccgtcaccggccgggtgcagaacaacggccaatcctgcatc
gccgccaagcggttcatcgtccacgccgacatttacgacgatttcgtcgacaagttcgtc
gcgcggatggcggcgttacgggtcggcgacccgaccgacccggacaccgacgtgggcccg
ctggccaccgagcagggccgcaacgaggttgccaagcaagtcgaggatgctgccgcggcg
ggcgcggtgatccggtgcggcggaaagcgtctcgaccggccgggctggttctacccgccg
accgtgatcaccgacatctccaaggacatggctctctacaccgaggaggtcttcggtccg
gtcgcctcggtgttccgcgcggcgaacatcgacgaggccgtcgagatcgccaacgccacc
accttcgggctgggatccaacgcctggacccgcgacgagaccgagcaacgacgcttcatc
gacgacatcgtggcgggccaggtttttatcaacggcatgacggtgtcctatcccgaattg
ccgttcggcggggtcaagcgctcgggctatggccgggaactgtccgcacacgggatacgc
gagttctgcaacatcaagaccgtctggatcgcctag

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