KEGG   Mycobacterium tuberculosis H37Rv: Rv0423c
Entry
Rv0423c           CDS       T00015                                 
Symbol
thiC
Name
(RefSeq) phosphomethylpyrimidine synthase
  KO
K03147  phosphomethylpyrimidine synthase [EC:4.1.99.17]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00730  Thiamine metabolism
mtu01100  Metabolic pathways
mtu01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    Rv0423c (thiC)
Enzymes [BR:mtu01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.99  Other carbon-carbon lyases
    4.1.99.17  phosphomethylpyrimidine synthase
     Rv0423c (thiC)
SSDB
Motif
Pfam: ThiC_Rad_SAM ThiC-associated
Other DBs
NCBI-GeneID: 886379
NCBI-ProteinID: NP_214937
TubercuList: Rv0423c
UniProt: P9WG79
Position
complement(508582..510225)
AA seq 547 aa
MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT
DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV
IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR
VYLPITQ
NT seq 1644 nt   +upstreamnt  +downstreamnt
atgaccatcaccgttgaaccgtcggtgaccacgggtcccatcgcgggcagcgccaaggcc
taccgtgaaatcgaggctcccggcagcggagctactctccaagtcccgtttcgacgggtg
cacttgtccaccggagaccacttcgacctctacgacacctccgggccctacaccgacacg
gacacggtgatcgacctgaccgcggggctgccgcataggcccggagtggttcgcgatcgg
ggcacccagctgcagcgggcccgcgccggggagatcaccgccgagatggcgttcatcgcc
gcccgcgaagacatgtccgccgagctagtgcgcgacgaggtcgcccgcggccgcgcggtg
atcccggccaaccaccaccaccccgagagcgagccgatgatcatcggcaaggcgttcgcg
gtgaaagtcaacgccaacatcggcaactcggcggtgacgagctcgatcgccgaggaggtc
gacaagatggtgtgggccacccgctggggggccgacaccatcatggacctgtccaccggc
aagaacatccacgaaacccgcgagtggatcctgcgcaattctcccgtgccggtcggcacc
gtgccgatctatcaggcgctggagaaagtcaagggcgatccgaccgagctgacctgggag
atctaccgcgacaccgtgatcgagcagtgtgagcaaggcgtggactacatgacggtgcac
gccggggtgctgctgcggtatgtgccgctgaccgccaagcgggtcaccggcatcgtgtcc
cgcgggggttcgatcatggccgcgtggtgtttggcacatcatcgggagtcgttcttgtac
accaactttgaggagctctgcgatattttcgcccgctacgacgtcaccttctcactcggt
gacgggctgcgaccagggtcgatcgctgatgccaacgacgccgcgcagttcgccgagctg
cgcaccctgggcgagctcaccaagatcgccaaagcccatggcgcacaggtgatgatcgag
gggccgggccatatcccaatgcacaagatcgtcgagaatgtgcggctggaagaggaactg
tgtgaggaggccccgttctacacgctgggtccgctggccaccgacatcgcgccggcctac
gaccacatcacctcggcgatcggtgcggccatcatcgcccaagccggtaccgcgatgctg
tgctacgtcacccccaaggagcacctcgggttgccggaccgcaaggacgtcaaggacggg
gtgatcgcctacaagatcgccgcgcatgcggccgatttggccaagggccatccgcgcgcc
caggagcgcgacgacgctttgagcacggcgcgtttcgagttccgctggaacgaccagttc
gcactgtcgctggatcccgacaccgcacgggaattccacgacgaaaccctgccggcggag
ccggccaagaccgcgcacttctgctcgatgtgcggaccgaagttctgctccatgcgcatc
acccaggacgtccgtgagtacgccgccgaacacgggcttgagaccgaagcggacatcgaa
gccgtgctcgccgccggaatggccgaaaagtcacgtgaattcgcagagcacggcaatcgg
gtgtatctcccgataacccagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (3)   
   KEGG MODULE (4)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (35)   

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