KEGG   Mycobacterium tuberculosis H37Rv: Rv1547
Entry
Rv1547            CDS       T00015                                 
Symbol
dnaE1
Name
(RefSeq) DNA polymerase III subunit alpha
  KO
K02337  DNA polymerase III subunit alpha [EC:2.7.7.7]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu03030  DNA replication
mtu03430  Mismatch repair
mtu03440  Homologous recombination
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    Rv1547 (dnaE1)
   03430 Mismatch repair
    Rv1547 (dnaE1)
   03440 Homologous recombination
    Rv1547 (dnaE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mtu03032]
    Rv1547 (dnaE1)
   03400 DNA repair and recombination proteins [BR:mtu03400]
    Rv1547 (dnaE1)
Enzymes [BR:mtu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     Rv1547 (dnaE1)
DNA replication proteins [BR:mtu03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    DNA polymerase III holoenzyme
     Rv1547 (dnaE1)
DNA repair and recombination proteins [BR:mtu03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    DNA polymerase III holoenzyme
     Rv1547 (dnaE1)
SSDB
Motif
Pfam: DNA_pol3_alpha DNA_pol3_finger PHP HHH_6 tRNA_anti-codon DNA_pol_IIIA_C
Other DBs
NCBI-GeneID: 886392
NCBI-ProteinID: NP_216063
TubercuList: Rv1547
UniProt: P9WNT7
Structure
Position
1747694..1751248
AA seq 1184 aa
MSGSSAGSSFVHLHNHTEYSMLDGAAKITPMLAEVERLGMPAVGMTDHGNMFGASEFYNS
ATKAGIKPIIGVEAYIAPGSRFDTRRILWGDPSQKADDVSGSGSYTHLTMMAENATGLRN
LFKLSSHASFEGQLSKWSRMDAELIAEHAEGIIITTGCPSGEVQTRLRLGQDREALEAAA
KWREIVGPDNYFLELMDHGLTIERRVRDGLLEIGRALNIPPLATNDCHYVTRDAAHNHEA
LLCVQTGKTLSDPNRFKFDGDGYYLKSAAEMRQIWDDEVPGACDSTLLIAERVQSYADVW
TPRDRMPVFPVPDGHDQASWLRHEVDAGLRRRFPAGPPDGYRERAAYEIDVICSKGFPSY
FLIVADLISYARSAGIRVGPGRGSAAGSLVAYALGITDIDPIPHGLLFERFLNPERTSMP
DIDIDFDDRRRGEMVRYAADKWGHDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADR
ITKALPPAIMAKDIPLSGITDPSHERYKEAAEVRGLIETDPDVRTIYQTARGLEGLIRNA
GVHACAVIMSSEPLTEAIPLWKRPQDGAIITGWDYPACEAIGLLKMDFLGLRNLTIIGDA
IDNVRANRGIDLDLESVPLDDKATYELLGRGDTLGVFQLDGGPMRDLLRRMQPTGFEDVV
AVIALYRPGPMGMNAHNDYADRKNNRQAIKPIHPELEEPLREILAETYGLIVYQEQIMRI
AQKVASYSLARADILRKAMGKKKREVLEKEFEGFSDGMQANGFSPAAIKALWDTILPFAD
YAFNKSHAAGYGMVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRKLGITVLP
PDVNESGLNFASVGQDIRYGLGAVRNVGANVVGSLLQTRNDKGKFTDFSDYLNKIDISAC
NKKVTESLIKAGAFDSLGHARKGLFLVHSDAVDSVLGTKKAEALGQFDLFGSNDDGTGTA
DPVFTIKVPDDEWEDKHKLALEREMLGLYVSGHPLNGVAHLLAAQVDTAIPAILDGDVPN
DAQVRVGGILASVNRRVNKNGMPWASAQLEDLTGGIEVMFFPHTYSSYGADIVDDAVVLV
NAKVAVRDDRIALIANDLTVPDFSNAEVERPLAVSLPTRQCTFDKVSALKQVLARHPGTS
QVHLRLISGDRITTLALDQSLRVTPSPALMGDLKELLGPGCLGS
NT seq 3555 nt   +upstreamnt  +downstreamnt
atgagcggttcatctgcggggtcctccttcgtgcacctgcacaaccacaccgagtattcg
atgctggacggtgccgcgaagatcacgcccatgctcgccgaggtggagcggctggggatg
cccgcggtggggatgaccgaccacggaaacatgttcggtgccagcgagttctacaactcc
gcgaccaaggccgggatcaagccgatcatcggcgtggaggcatacatcgcgccgggctcg
cggttcgacacccggcgcatcctgtggggtgaccccagccaaaaggccgacgacgtctcc
ggcagcggctcctacacgcacctgacgatgatggccgagaacgccaccggtctgcgcaac
ctgttcaagctgtcctcgcatgcttccttcgagggccagctgagcaagtggtcgcgcatg
gacgccgagctcatcgccgaacacgccgagggcatcatcatcaccaccggatgcccgtcg
ggggaggtgcagacccgcctgcggctcggccaggatcgggaggcgctcgaagccgcggcg
aagtggcgggagatcgtcggaccggacaactacttccttgagctgatggaccacgggctg
accatcgaacgccgggtccgtgacggtctgctcgagatcggacgcgcgctcaacattccg
cctcttgccaccaatgactgccactacgtgacccgcgacgccgcccacaaccatgaggct
ttgttgtgtgtgcagaccggcaagaccctctcggatccgaatcgcttcaagttcgacggt
gacggctactacctgaagtcggccgccgagatgcgccagatctgggacgacgaagtgccg
ggcgcgtgtgactccaccttgttgatcgccgaacgggtgcagtcctacgccgacgtgtgg
acaccgcgcgaccggatgcccgtgtttccggtgcccgatgggcatgaccaggcgtcctgg
ctgcgtcacgaggtggacgccgggcttcgccggcgatttccggccggtccgccggacggg
taccgcgagcgcgccgcctacgagatcgacgtcatctgctccaaaggtttcccatcgtac
tttctgatcgtcgccgacctgatcagctacgcgcggtcggcgggcataagggtgggtccc
ggccgcggctcggccgccggctcgctggtcgcctacgcgctgggcatcaccgacatcgac
ccgattccacacggtctgctgttcgagcggttcctcaaccccgagcgcacctcgatgccc
gacatcgatatcgacttcgacgaccggcgccgcggtgagatggtgcgctacgcagccgac
aagtggggccacgaccgggtcgcgcaggtcatcaccttcggcaccatcaaaaccaaagcg
gcgctgaaggattcggcgcgaatccactacgggcagcccgggttcgccatcgccgaccgg
atcaccaaggcgttgccgccggcgatcatggccaaagacatcccgctgtctgggatcacc
gatcccagccacgaacggtacaaggaggccgccgaggtccgcggcctgatcgaaaccgac
ccggacgtacgcaccatctaccagaccgcacgcgggttggaaggcctgatccgcaacgcg
ggtgtgcacgcctgcgcggtgatcatgagcagcgagccgctgactgaggccatcccgttg
tggaagcggccgcaggacggggccatcatcaccggctgggattacccggcgtgcgaggcc
atcggtctgctgaaaatggacttcctgggcctgcggaacctgacgatcatcggcgacgcg
atcgacaacgtcagggccaacaggggtatcgacctcgacctggaatccgtgccgctggac
gacaaggccacctatgagctgctgggccgcggcgacaccctgggcgtgttccagctcgac
ggcgggcccatgcgcgacctgctgcgccgcatgcagccgaccgggttcgaagacgtcgtc
gccgttatcgcgctgtaccggcccggcccgatgggcatgaacgcacacaacgactatgcc
gaccgcaagaacaaccggcaggccatcaaacctattcacccggaactcgaagaaccgctg
cgcgagatcctcgccgagacctacggcctcatcgtctatcaagagcagatcatgcgcatc
gcgcagaaggtggcgagctactcgttggcccgcgccgacattctacgcaaggccatgggc
aagaagaaacgcgaggtgctggagaaggagttcgagggcttctccgatggcatgcaggcc
aacgggttctctccggcggccatcaaggcgctgtgggacaccatcctgccgttcgctgac
tacgcgttcaacaagtcacatgccgccggctacggcatggtgtcctactggacggcctac
ctcaaggccaactatcccgccgagtacatggccggtctgttgacgtcggtcggcgacgat
aaagacaaggccgcggtttatctggccgactgccgcaagctcggcatcaccgtgctcccg
cccgacgtcaacgaatctggcttgaacttcgcatcggtcggccaagacatccgctacggg
ctgggcgcggtgcgcaacgttggcgctaatgtcgtgggctcgttgctccaaacccgcaac
gacaagggcaagttcaccgacttttcggactacctgaacaagatcgacatctcggcgtgc
aacaagaaggtgaccgaatcgctgatcaaggcgggtgcgttcgactcgctggggcatgcc
cgcaagggtcttttcctggtgcacagcgatgcggtggactcggtgctgggcaccaagaag
gccgaggcactggggcagttcgatctcttcggcagcaatgatgatgggaccggcaccgca
gatcccgtgttcaccatcaaggtgcccgatgatgagtgggaggacaaacacaaactcgcc
ctagagcgcgagatgctgggactgtacgtctcggggcatcccctcaacggtgtggcacac
ttgctggctgcccaggtcgacaccgcgatcccagcgatcctcgacggcgatgtccccaac
gatgcccaagtgcgggtgggcggcatcctggcgtcggtgaaccggagggtcaacaaaaac
ggaatgccatgggcttcagcgcaattggaggatctcacgggcggcatcgaggtgatgttc
ttcccgcacacctactccagctatggtgccgacatcgtcgacgatgccgtcgtgctggtc
aacgccaaggtggcggtccgtgacgaccgcatcgcattgatcgccaatgacctcacagtg
cccgacttttccaacgccgaggtggagcggccgctggcggtcagcttgcccacccggcag
tgcacctttgacaaggtgagtgcgctcaaacaggtgttggcgcgccaccccggcacctcg
caggtgcatctgcggctcatcagcggagaccggatcaccacgctggcacttgatcagtcg
ttgcgggtgacgccgtcgccggcgttgatgggtgacctcaaggagctgctcggccctgga
tgtctggggagttag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (48)   

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