KEGG   Mycobacterium tuberculosis H37Rv: Rv1603
Entry
Rv1603            CDS       T00015                                 
Symbol
hisA
Name
(RefSeq) 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
  KO
K24017  phosphoribosyl isomerase A [EC:5.3.1.16 5.3.1.24]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00340  Histidine metabolism
mtu00400  Phenylalanine, tyrosine and tryptophan biosynthesis
mtu01100  Metabolic pathways
mtu01110  Biosynthesis of secondary metabolites
mtu01230  Biosynthesis of amino acids
Module
mtu_M00026  Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00340 Histidine metabolism
    Rv1603 (hisA)
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    Rv1603 (hisA)
Enzymes [BR:mtu01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.1  Interconverting aldoses and ketoses, and related compounds
    5.3.1.16  1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
     Rv1603 (hisA)
    5.3.1.24  phosphoribosylanthranilate isomerase
     Rv1603 (hisA)
SSDB
Motif
Pfam: His_biosynth NMO Dus
Other DBs
NCBI-GeneID: 885873
NCBI-ProteinID: NP_216119
TubercuList: Rv1603
UniProt: P9WMM5
Structure
Position
1803294..1804031
AA seq 245 aa
MMPLILLPAVDVVEGRAVRLVQGKAGSQTEYGSAVDAALGWQRDGAEWIHLVDLDAAFGR
GSNHELLAEVVGKLDVQVELSGGIRDDESLAAALATGCARVNVGTAALENPQWCARVIGE
HGDQVAVGLDVQIIDGEHRLRGRGWETDGGDLWDVLERLDSEGCSRFVVTDITKDGTLGG
PNLDLLAGVADRTDAPVIASGGVSSLDDLRAIATLTHRGVEGAIVGKALYARRFTLPQAL
AAVRD
NT seq 738 nt   +upstreamnt  +downstreamnt
gtgatgccgctgatacttttgcccgccgtcgacgtggtcgagggtcgtgccgtgcgcctc
gttcaagggaaggccggcagccaaaccgagtacggctcagcggtggatgccgcgttgggc
tggcaacgcgatggcgccgagtggatccatttggtggacctggatgctgcgttcggccgc
ggttccaaccacgaactgcttgccgaggttgtcggcaagctcgacgtacaggttgagcta
tccggcggtattcgagacgacgagtcgctggccgcggcgctggccaccggatgcgctcgg
gtcaatgtgggcactgctgccctggaaaacccgcagtggtgtgcccgggtgattggcgag
cacggcgaccaggtcgccgtcggcttggacgtccagatcatcgacggcgagcatcggttg
cgcggacgcggctgggaaaccgacggcggcgacctgtgggacgtgctagaacgcctagac
agtgaaggatgttcgcggttcgtcgtgaccgatatcaccaaggacggcaccctgggcggc
cccaatctggacctgctggccggtgttgccgaccgcaccgacgccccggtgatcgcgtcc
ggaggtgtgtccagcctcgatgacctgcgcgccattgcgactctcacgcaccgcggcgtc
gagggggccatcgtcggcaaggccctctacgcccgtcggttcaccttgccgcaagcgttg
gccgcggttcgggactag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (4)   
   PDB (4)   
Protein domain (3)   
   Pfam (3)   
All databases (39)   

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