KEGG T00015: Rv1617

Mycobacterium tuberculosis H37Rv: Rv1617

Entry

Rv1617            CDS       T00015

Symbol

pykA

Name

(RefSeq) pyruvate kinase

K00873

pyruvate kinase [EC:2.7.1.40]

Organism

mtu Mycobacterium tuberculosis H37Rv

Pathway

mtu00010

Glycolysis / Gluconeogenesis

mtu00620

Pyruvate metabolism

mtu01100

Metabolic pathways

mtu01110

Biosynthesis of secondary metabolites

mtu01120

Microbial metabolism in diverse environments

mtu01200

Carbon metabolism

mtu01230

Biosynthesis of amino acids

Module

mtu_M00001

Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate

mtu_M00002

Glycolysis, core module involving three-carbon compounds

Brite

KEGG Orthology (KO) [BR:mtu00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    Rv1617 (pykA)
   00620 Pyruvate metabolism
    Rv1617 (pykA)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mtu04131]
    Rv1617 (pykA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mtu04147]
    Rv1617 (pykA)
Enzymes [BR:mtu01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.40  pyruvate kinase
     Rv1617 (pykA)
Membrane trafficking [BR:mtu04131]
Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    Rv1617 (pykA)
Exosome [BR:mtu04147]
Exosomal proteins
  Proteins found in most exosomes
   Rv1617 (pykA)

SSDB

Motif

Pfam:

PK PK_C HpcH_HpaI

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

TubercuList:

UniProt:

Structure

Position

1816189..1817607

AA seq 472 aa
MTRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGR
AVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGD
RVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFA
LNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMV
ARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAV
LDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARD
IGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQ
STDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV

NT seq 1419 nt +upstreamnt +downstreamnt
gtgacgagacgcgggaaaatcgtctgcactctcgggccggccacccagcgggacgacctg
gtcagagcgctggtcgaggccggaatggacgtcgcccgaatgaacttcagccacggcgac
tacgacgatcacaaggtcgcctatgagcgggtccgggtagcctccgacgccaccgggcgc
gcggtcggcgtgctcgccgacctgcagggcccgaagatcaggttgggacgcttcgcctcc
ggggccacccactgggccgaaggcgaaaccgtccggatcaccgtgggcgcctgcgagggc
agccacgatcgggtgtccaccacctacaagcggctagcccaggacgcggtggccggtgac
cgggtgctggtcgacgacggcaaagtcgcattggtggtcgacgccgtcgagggcgacgac
gtggtctgcaccgtcgtcgaaggcggcccggtcagcgacaacaagggcatctcgttgccc
ggaatgaacgtgaccgcgccggccctgtcggagaaggacatcgaggatctcacgttcgcg
ctgaacctcggcgtcgacatggtggcgctttccttcgtccgctccccggccgatgtcgaa
ctggtccacgaggtgatggatcggatcgggcgacgggtgccggtgatcgccaagctggag
aagccggaagccatcgacaatctcgaagcgatcgtgctggcgttcgacgccgtcatggtc
gctcggggcgacctaggtgttgagctgccgctcgaagaggtcccgctggtacagaagcga
gccatccagatggcccgggagaacgccaagccggtcattgtggcgacccagatgctcgac
tcgatgatcgagaactcgcggccgacccgagctgaggcctccgacgtcgccaacgcggtg
ctcgatggcgccgacgcgctgatgctgtccggggaaacctcggtagggaagtaccccctt
gctgcggtccggacaatgtcgcgcatcatctgcgcggtcgaggagaactccacggccgca
ccgccgttgacacacattccccggaccaagcgtggggtcatctcgtatgcggcccgtgac
atcggcgaacgactcgacgccaaggccttggtggccttcactcagtccggtgataccgtg
cggcgactggcccgcctgcataccccgctgccgctgctggccttcaccgcgtggcccgag
gtgcgcagccaactggcgatgacctggggcaccgagacgttcatcgtgccgaagatgcag
tccaccgatggcatgatccgccaggtcgacaaatcgctgctcgaactcgcccgctacaag
cgtggtgacttggtggtcatcgtcgcgggtgcgccgccaggcacagtgggttcgaccaac
ctgatccacgtgcaccggatcggggaagatgacgtctag

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