KEGG   Mycobacterium tuberculosis H37Rv: Rv2764c
Entry
Rv2764c           CDS       T00015                                 
Symbol
thyA
Name
(RefSeq) thymidylate synthase ThyA
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00240  Pyrimidine metabolism
mtu00670  One carbon pool by folate
mtu01100  Metabolic pathways
mtu01232  Nucleotide metabolism
Module
mtu_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    Rv2764c (thyA)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Rv2764c (thyA)
Enzymes [BR:mtu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     Rv2764c (thyA)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-GeneID: 887728
NCBI-ProteinID: NP_217280
TubercuList: Rv2764c
UniProt: P9WFR9
Structure
Position
complement(3073680..3074471)
AA seq 263 aa
MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL
WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR
TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS
YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE
YTYEDIVVKNYDPHPAIKAPVAV
NT seq 792 nt   +upstreamnt  +downstreamnt
gtgacgccatacgaggacctgctgcgcttcgtgctcgaaacgggtacgcccaaatccgac
cgcaccggcaccggaacccgcagcctgttcggccagcagatgcgctatgatttgtcggcc
ggtttcccgctgctcactaccaagaaagtccatttcaaatcggtagcctacgagctgctg
tggtttttgcgcggcgattccaatatcggttggctgcacgagcacggagtcaccatctgg
gacgaatgggcaagtgatacaggcgaactcgggccgatctacggtgtacaatggcgatcg
tggccggctccatccggtgagcacatcgaccagatcagcgcggcgctggatttgctgcgc
accgatcccgattcccggcgcatcatcgtgtcggcctggaacgtcggcgaaatcgagcgg
atggcgctgccgccctgtcatgcgttcttccagttctacgtcgccgatggccggctgagc
tgtcagctctaccaacgcagcgccgacctgtttctgggtgtgccgttcaacatcgccagc
tatgcgttgctcacccacatgatggccgcccaggccggcttgtcggtcggcgagttcatc
tggaccggtggcgactgccacatctacgacaatcacgtcgagcaagtacggctgcagctc
agccgcgagccgcggccatatccgaaactacttctagccgaccgggattcaatcttcgag
tacacctatgaagacatcgttgtgaagaactacgatccgcatccggcgatcaaagctcca
gtcgcggtatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (5)   
   PDB (5)   
Protein domain (1)   
   Pfam (1)   
All databases (36)   

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