#=GF ID AP3B1_C
#=GF AC PF14796.10
#=GF DE Clathrin-adaptor complex-3 beta-1 subunit C-terminal
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE Pfam-B_195384 (release 26.0)
#=GF GA 27.00 27.00;
#=GF TC 27.00 27.00;
#=GF NC 26.90 26.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 9151686
#=GF RT Characterization of the adaptor-related protein complex, AP-3.
#=GF RA Simpson F, Peden AA, Christopoulou L, Robinson MS;
#=GF RL J Cell Biol. 1997;137:835-845.
#=GF RN [2]
#=GF RM 10024875
#=GF RT Altered trafficking of lysosomal proteins in Hermansky-Pudlak
#=GF RT syndrome due to mutations in the beta 3A subunit of the AP-3
#=GF RT adaptor.
#=GF RA Dell'Angelica EC, Shotelersuk V, Aguilar RC, Gahl WA, Bonifacino
#=GF RA JS;
#=GF RL Mol Cell. 1999;3:11-21.
#=GF DR INTERPRO; IPR029390;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This domain lies at the C-terminus of the clathrin-adaptor
#=GF CC protein complex-3 beta-1 subunit. The AP-3 complex is associated
#=GF CC with the Golgi region of the cell as well as with more
#=GF CC peripheral structures. The AP-3 complex may be directly involved
#=GF CC in trafficking to lysosomes or alternatively it may be involved
#=GF CC in another pathway, but that mis-sorting in that pathway may
#=GF CC indirectly lead to defects in pigment granules [2].
#=GF SQ 2638
#=GS A0A2K5QB68_CEBIM/772-923 AC A0A2K5QB68.1
#=GS A0A8C7L436_ONCKI/731-868 AC A0A8C7L436.1
#=GS A0A7L4BHP0_9CHAR/816-962 AC A0A7L4BHP0.1
#=GS A0A7J5YLC1_DISMA/740-884 AC A0A7J5YLC1.1
#=GS A0A8P0THP7_CANLF/787-933 AC A0A8P0THP7.1
#=GS A0A7K9PML4_9CORV/772-821 AC A0A7K9PML4.1
#=GS A0A7K7GI80_ERIRU/844-990 AC A0A7K7GI80.1
#=GS A0A672UD48_STRHB/576-714 AC A0A672UD48.1
#=GS A0A8I5TY05_PONAB/802-947 AC A0A8I5TY05.1
#=GS A0A663M6T7_ATHCN/815-923 AC A0A663M6T7.1
#=GS A0A3Q1M917_BOVIN/778-914 AC A0A3Q1M917.1
#=GS A0A5F9CML7_RABIT/857-1002 AC A0A5F9CML7.1
#=GS A0A8C1DU67_CYPCA/806-924 AC A0A8C1DU67.1
#=GS A0A7K7L3U7_9AVES/794-940 AC A0A7K7L3U7.1
#=GS A0A1S3LS76_SALSA/822-966 AC A0A1S3LS76.1
#=GS A0A1S3KGN8_LINUN/796-961 AC A0A1S3KGN8.1
#=GS A0A672QGS2_SINGR/793-939 AC A0A672QGS2.1
#=GS A0A834N215_VESVU/777-915 AC A0A834N215.1
#=GS A0A8C3FFB8_CHRPI/970-1116 AC A0A8C3FFB8.1
#=GS A0A671LMG5_9TELE/723-847 AC A0A671LMG5.1
#=GS A0A0K0EVS8_STRVS/710-830 AC A0A0K0EVS8.1
#=GS A0A8I5NSJ2_PAPAN/782-928 AC A0A8I5NSJ2.1
#=GS V4TGF8_CITCL/824-943 AC V4TGF8.1
#=GS A0A8U8C4U0_GEOPR/833-979 AC A0A8U8C4U0.1
#=GS A0A1U7Y9J7_NICSY/821-923 AC A0A1U7Y9J7.1
#=GS A0A7L0MSC7_9PSIT/790-936 AC A0A7L0MSC7.1
#=GS A0A5G2RC09_PIG/776-922 AC A0A5G2RC09.1
#=GS A0A2I4AXB6_9TELE/804-948 AC A0A2I4AXB6.1
#=GS A0A445H2L6_GLYSO/684-780 AC A0A445H2L6.1
#=GS A0A8W8HUT0_CRAGI/803-954 AC A0A8W8HUT0.1
#=GS A0A369RUF7_9METZ/772-926 AC A0A369RUF7.1
#=GS A0A3Q1BV41_AMPOC/817-961 AC A0A3Q1BV41.1
#=GS A0A2R6RRF3_ACTCC/812-928 AC A0A2R6RRF3.1
#=GS A0A8P0NWU2_CANLF/783-929 AC A0A8P0NWU2.1
#=GS A0A8C1DU99_CYPCA/697-815 AC A0A8C1DU99.1
#=GS A0A183IDI6_9BILA/856-1000 AC A0A183IDI6.1
#=GS A0A671V0V1_SPAAU/752-883 AC A0A671V0V1.1
#=GS A0A067R759_ZOONE/813-956 AC A0A067R759.1
#=GS A0A669QFM6_PHACC/640-761 AC A0A669QFM6.1
#=GS A0A8C4LE15_EQUAS/761-906 AC A0A8C4LE15.1
#=GS A0A673HDS4_9TELE/591-745 AC A0A673HDS4.1
#=GS W5JEI3_ANODA/893-1038 AC W5JEI3.1
#=GS A0A7J7R1S9_MYOMY/759-904 AC A0A7J7R1S9.1
#=GS A0A821MCE0_9BILA/78-171 AC A0A821MCE0.1
#=GS A0A674N3N0_TAKRU/775-882 AC A0A674N3N0.1
#=GS A0A6P8W1U3_GYMAC/830-976 AC A0A6P8W1U3.1
#=GS A0A8C4ISH7_DICLA/639-757 AC A0A8C4ISH7.2
#=GS A0A8C6V006_9GOBI/688-824 AC A0A8C6V006.1
#=GS A0A6A5MBN2_LUPAL/801-931 AC A0A6A5MBN2.1
#=GS A0A7L3NSV0_9AVES/760-818 AC A0A7L3NSV0.1
#=GS A0A210QFK3_MIZYE/804-958 AC A0A210QFK3.1
#=GS A0A1S3KLK9_SALSA/890-1037 AC A0A1S3KLK9.1
#=GS A0A674D0A9_SALTR/765-899 AC A0A674D0A9.1
#=GS A0A452R2A7_URSAM/795-935 AC A0A452R2A7.1
#=GS A0A3Q4FZF9_NEOBR/576-695 AC A0A3Q4FZF9.1
#=GS A0A667GZE2_LYNCA/757-903 AC A0A667GZE2.1
#=GS A0A4W6CC87_LATCA/722-845 AC A0A4W6CC87.1
#=GS A0A7N8X8J4_9TELE/716-831 AC A0A7N8X8J4.1
#=GS A0A2S2QKX4_9HEMI/773-924 AC A0A2S2QKX4.1
#=GS A0A6J2VN06_CHACN/759-904 AC A0A6J2VN06.1
#=GS A0A669Q8B4_PHACC/629-775 AC A0A669Q8B4.1
#=GS A0A8B9FY09_9PSIT/658-794 AC A0A8B9FY09.1
#=GS A0A485P8W7_LYNPA/807-952 AC A0A485P8W7.1
#=GS A0A261BWQ1_9PELO/667-783 AC A0A261BWQ1.1
#=GS A0A8C8BP08_9STRI/701-815 AC A0A8C8BP08.1
#=GS A0A672UPZ8_STRHB/817-935 AC A0A672UPZ8.1
#=GS A0A8C8EEN2_9STRI/767-900 AC A0A8C8EEN2.1
#=GS B4R4I3_DROSI/869-1020 AC B4R4I3.1
#=GS G4ZJU5_PHYSP/820-956 AC G4ZJU5.1
#=GS A0A8C9LBX6_PAVCR/774-880 AC A0A8C9LBX6.1
#=GS A0A5N4CFU2_CAMDR/1020-1165 AC A0A5N4CFU2.1
#=GS A0A3P8W5T7_CYNSE/824-969 AC A0A3P8W5T7.1
#=GS A0A7K8Q1R6_COCCO/779-925 AC A0A7K8Q1R6.1
#=GS A0A7L0QQR3_SETKR/807-953 AC A0A7L0QQR3.1
#=GS A0A6P3ZNJ5_ZIZJJ/822-938 AC A0A6P3ZNJ5.1
#=GS A0A8B9ECF8_ANSCY/933-1079 AC A0A8B9ECF8.1
#=GS A0A7K5J2C3_TOXRE/790-936 AC A0A7K5J2C3.1
#=GS A0A8C7Z4V6_9TELE/825-969 AC A0A8C7Z4V6.1
#=GS A0A7K4QFC6_9TYRA/790-936 AC A0A7K4QFC6.1
#=GS A0A067G1E4_CITSI/689-806 AC A0A067G1E4.1
#=GS A0A2I4C8Z1_9TELE/851-997 AC A0A2I4C8Z1.1
#=GS F4PQY8_CAVFA/748-870 AC F4PQY8.1
#=GS A0A8C9DVZ4_PHOSS/748-893 AC A0A8C9DVZ4.1
#=GS A0A4W4GMX5_ELEEL/719-862 AC A0A4W4GMX5.1
#=GS A0A7N6APG6_ANATE/654-788 AC A0A7N6APG6.1
#=GS A0A2K5I3A4_COLAP/771-916 AC A0A2K5I3A4.1
#=GS G5B1R3_HETGA/770-915 AC G5B1R3.1
#=GS A0A2U4AX28_TURTR/805-951 AC A0A2U4AX28.1
#=GS A0A3P8UWV0_CYNSE/841-987 AC A0A3P8UWV0.1
#=GS A0A8B9USK4_9AVES/894-1040 AC A0A8B9USK4.1
#=GS A0A8J0U9Q2_XENLA/815-959 AC A0A8J0U9Q2.1
#=GS A0A8C6LXJ0_NOTFU/677-818 AC A0A8C6LXJ0.1
#=GS A0A7K6LX53_9CORV/790-936 AC A0A7K6LX53.1
#=GS A0A8B8MTV3_9MYRT/695-792 AC A0A8B8MTV3.1
#=GS A0A0V0ZQ11_9BILA/759-911 AC A0A0V0ZQ11.1
#=GS A0A6G0TUN4_APHGL/773-923 AC A0A6G0TUN4.1
#=GS A0A6J1N7N0_BICAN/765-908 AC A0A6J1N7N0.1
#=GS A0A803T2X3_ANOCA/655-774 AC A0A803T2X3.1
#=GS V4BIB9_LOTGI/777-919 AC V4BIB9.1
#=GS A0A669CKP5_ORENI/725-844 AC A0A669CKP5.1
#=GS A0A8B9M4F9_9AVES/727-860 AC A0A8B9M4F9.1
#=GS A0A093QAK8_9PASS/755-901 AC A0A093QAK8.1
#=GS A0A6P5L6U4_PHACI/806-952 AC A0A6P5L6U4.1
#=GS A0A093QLY7_PHACA/570-719 AC A0A093QLY7.1
#=GS A0A8C4YCH3_9SAUR/833-979 AC A0A8C4YCH3.1
#=GS A0A8C8BP50_9STRI/663-798 AC A0A8C8BP50.1
#=GS A0A8Q3WKK0_HUMAN/767-913 AC A0A8Q3WKK0.1
#=GS E2AQ74_CAMFO/774-912 AC E2AQ74.1
#=GS A0A2Y9S3M1_PHYMC/773-918 AC A0A2Y9S3M1.1
#=GS A0A8D2D1E2_SCIVU/809-955 AC A0A8D2D1E2.1
#=GS A0A674HQD1_TAEGU/773-919 AC A0A674HQD1.1
#=GS A0A817DVF4_9BILA/209-333 AC A0A817DVF4.1
#=GS A0A5D6XKF3_9STRA/837-999 AC A0A5D6XKF3.1
#=GS A0A8C7HTL5_ONCKI/827-971 AC A0A8C7HTL5.1
#=GS A0A8B8MSL8_9MYRT/827-959 AC A0A8B8MSL8.1
#=GS A0A8C3WI32_9CETA/808-954 AC A0A8C3WI32.1
#=GS A0A8I3N509_CANLF/809-955 AC A0A8I3N509.1
#=GS A0A7J6DJ84_CANSA/819-924 AC A0A7J6DJ84.1
#=GS A0A2I3SW12_PANTR/758-904 AC A0A2I3SW12.1
#=GS A0A7N6A2Z3_ANATE/718-855 AC A0A7N6A2Z3.1
#=GS T1FWW7_HELRO/774-914 AC T1FWW7.1
#=GS A0A6J5WNG5_PRUAR/136-245 AC A0A6J5WNG5.1
#=GS A0A672K1G5_SINGR/699-817 AC A0A672K1G5.1
#=GS A0A663M703_ATHCN/719-859 AC A0A663M703.1
#=GS A0A813U0W3_9BILA/842-988 AC A0A813U0W3.1
#=GS G3USB5_MELGA/452-598 AC G3USB5.2
#=GS A0A8C8BK64_9STRI/711-846 AC A0A8C8BK64.1
#=GS E0VMB8_PEDHC/787-929 AC E0VMB8.1
#=GS A0A571BEW4_MOUSE/770-915 AC A0A571BEW4.1
#=GS A0A8I3N660_CANLF/702-848 AC A0A8I3N660.1
#=GS A0A8C7ZJS3_9TELE/787-905 AC A0A8C7ZJS3.1
#=GS A0A2J8JA28_PANTR/802-947 AC A0A2J8JA28.1
#=GS AP3B2_MOUSE/802-947 AC Q9JME5.2
#=GS A0A8C3FA81_CHRPI/817-963 AC A0A8C3FA81.1
#=GS A0A540N9C9_MALBA/804-930 AC A0A540N9C9.1
#=GS A0A452R297_URSAM/763-903 AC A0A452R297.1
#=GS A0A8C6MM14_MOSMO/824-969 AC A0A8C6MM14.1
#=GS A0A7K6WB84_STECA/777-923 AC A0A7K6WB84.1
#=GS A0A6J2VN40_CHACN/791-936 AC A0A6J2VN40.1
#=GS A0A493TGM0_ANAPP/427-545 AC A0A493TGM0.1
#=GS A0A663DTY3_AQUCH/800-933 AC A0A663DTY3.1
#=GS A0A6P6N185_CARAU/811-955 AC A0A6P6N185.1
#=GS A0A2K5RWG9_CEBIM/823-968 AC A0A2K5RWG9.1
#=GS A0A1S3KLL1_SALSA/903-1050 AC A0A1S3KLL1.1
#=GS A0A8D2E9P4_THEGE/770-915 AC A0A8D2E9P4.1
#=GS A0A8C8EUH1_ONCTS/650-787 AC A0A8C8EUH1.1
#=GS A0A8C0FY22_BUBBB/665-802 AC A0A8C0FY22.1
#=GS A0A8C4ZV70_GADMO/683-823 AC A0A8C4ZV70.1
#=GS G0MFE7_CAEBE/663-771 AC G0MFE7.1
#=GS B4JKC1_DROGR/917-1066 AC B4JKC1.1
#=GS A0A3Q1FV73_9TELE/846-992 AC A0A3Q1FV73.1
#=GS A0A8C9ZRY1_SANLU/761-866 AC A0A8C9ZRY1.1
#=GS A0A8C0FT23_BUBBB/603-742 AC A0A8C0FT23.1
#=GS A0A7J8CDL2_ROUAE/384-529 AC A0A7J8CDL2.1
#=GS A0A6P5L7K1_PHACI/860-915 AC A0A6P5L7K1.1
#=GS A0A8C8JYR2_ONCTS/658-783 AC A0A8C8JYR2.1
#=GS AP3B1_CANLF/809-955 AC Q7YRF1.1
#=GS A0A8C9II54_9PRIM/753-899 AC A0A8C9II54.1
#=GS A0A6I9KEK8_CHRAS/832-978 AC A0A6I9KEK8.1
#=GS A0A6Q2XPN6_ESOLU/817-947 AC A0A6Q2XPN6.1
#=GS A0A8C5U846_9PASS/601-746 AC A0A8C5U846.1
#=GS A0A1S3KLL4_SALSA/841-988 AC A0A1S3KLL4.1
#=GS A0A8C2WYD6_CYCLU/732-876 AC A0A8C2WYD6.1
#=GS A0A7K5S5Q3_LANLU/571-717 AC A0A7K5S5Q3.1
#=GS A0A8C7Z3C2_9TELE/628-752 AC A0A8C7Z3C2.1
#=GS A0A7L0N660_9PASS/748-894 AC A0A7L0N660.1
#=GS A0A803U1S6_ANOCA/706-829 AC A0A803U1S6.1
#=GS A0A2K6MNW3_RHIBE/802-947 AC A0A2K6MNW3.1
#=GS A0A8C7L5G0_ONCKI/743-873 AC A0A8C7L5G0.1
#=GS A0A8C3YL93_9CETA/773-918 AC A0A8C3YL93.1
#=GS A0A8I3MQV2_CANLF/846-991 AC A0A8I3MQV2.1
#=GS A0A5N5L895_9ROSI/799-910 AC A0A5N5L895.1
#=GS A0A4W2D5X9_BOBOX/802-948 AC A0A4W2D5X9.1
#=GS A0A3Q1ART5_AMPOC/832-978 AC A0A3Q1ART5.1
#=GS A0A8C5VZ66_MICMU/809-954 AC A0A8C5VZ66.1
#=GS A0A437AWW4_CHISP/779-920 AC A0A437AWW4.1
#=GS A0A8C3TZT6_CATUS/734-870 AC A0A8C3TZT6.1
#=GS W5MF35_LEPOC/823-970 AC W5MF35.1
#=GS A0A851YW20_9AVES/738-884 AC A0A851YW20.1
#=GS F6X3Z0_MONDO/800-946 AC F6X3Z0.2
#=GS A0A2Y9LYT8_DELLE/805-950 AC A0A2Y9LYT8.1
#=GS A0A2K6MP33_RHIBE/787-932 AC A0A2K6MP33.1
#=GS A0A851KHP8_VIDCH/789-935 AC A0A851KHP8.1
#=GS A0A8C5V522_MICMU/828-973 AC A0A8C5V522.1
#=GS A0A6J3EFM1_AYTFU/820-967 AC A0A6J3EFM1.1
#=GS A0A7J8CDL7_ROUAE/659-804 AC A0A7J8CDL7.1
#=GS A0A8C9B2P4_PHOSS/805-950 AC A0A8C9B2P4.1
#=GS A0A8C7ZKP2_9TELE/612-727 AC A0A8C7ZKP2.1
#=GS A0A668T9T7_OREAU/697-820 AC A0A668T9T7.1
#=GS A0A093JDU8_FULGA/573-719 AC A0A093JDU8.1
#=GS A0A314ZXX8_PRUYE/703-816 AC A0A314ZXX8.1
#=GS A0A7M4ECI9_CROPO/848-961 AC A0A7M4ECI9.1
#=GS A0A8B7W5S0_CASCN/440-585 AC A0A8B7W5S0.1
#=GS A0A815FFF0_9BILA/501-642 AC A0A815FFF0.1
#=GS A0A8C3GNR0_CAIMO/825-971 AC A0A8C3GNR0.1
#=GS A0A8C7ZEM4_9TELE/708-847 AC A0A8C7ZEM4.1
#=GS A0A8K0DTT2_9ROSA/821-916 AC A0A8K0DTT2.1
#=GS A0A672JX94_SINGR/654-778 AC A0A672JX94.1
#=GS A0A261BXM3_9PELO/657-773 AC A0A261BXM3.1
#=GS A0A2K6DYF4_MACNE/812-958 AC A0A2K6DYF4.1
#=GS A0A3B3HLC4_ORYLA/840-986 AC A0A3B3HLC4.1
#=GS A0A7N8WSP6_9TELE/783-911 AC A0A7N8WSP6.1
#=GS A0A674JZQ4_TERCA/767-913 AC A0A674JZQ4.1
#=GS A0A8C5Z222_MARMA/753-889 AC A0A8C5Z222.1
#=GS A0A7J0E7A3_9ERIC/819-942 AC A0A7J0E7A3.1
#=GS A0A4W3JMZ9_CALMI/680-815 AC A0A4W3JMZ9.1
#=GS A0A6J2N5M4_9CHIR/803-949 AC A0A6J2N5M4.1
#=GS A0A2R5GN16_9STRA/874-1011 AC A0A2R5GN16.1
#=GS A0A8C5E0D1_9TELE/679-803 AC A0A8C5E0D1.1
#=GS A0A8C7ZH68_9TELE/740-874 AC A0A8C7ZH68.1
#=GS A0A5P1EUH1_ASPOF/810-957 AC A0A5P1EUH1.1
#=GS A0A8I3N6Q5_CANLF/825-970 AC A0A8I3N6Q5.1
#=GS A0A8C5JFE8_JUNHY/821-967 AC A0A8C5JFE8.1
#=GS A0A6J1WNQ4_GALME/1-105 AC A0A6J1WNQ4.1
#=GS A0A6J3HUY2_SAPAP/812-869 AC A0A6J3HUY2.1
#=GS A0A0D9RXI0_CHLSB/803-948 AC A0A0D9RXI0.1
#=GS AP3B1_HUMAN/812-958 AC O00203.3
#=GS A0A314Y7E0_PRUYE/803-919 AC A0A314Y7E0.1
#=GS A0A8C6Z4X6_NOTPE/796-940 AC A0A8C6Z4X6.1
#=GS A0A8C8K4K9_ONCTS/761-906 AC A0A8C8K4K9.1
#=GS A0A158RAN2_THECL/687-815 AC A0A158RAN2.1
#=GS A0A026WX82_OOCBI/778-916 AC A0A026WX82.1
#=GS A0A8C6Y8F0_NAJNA/644-783 AC A0A8C6Y8F0.1
#=GS A0A672J8T4_SALFA/730-876 AC A0A672J8T4.1
#=GS A0A7L4BWB0_9AVES/795-941 AC A0A7L4BWB0.1
#=GS A0A8D2QIZ4_ZONAL/777-923 AC A0A8D2QIZ4.1
#=GS A0A8J2MUG6_9BILA/692-800 AC A0A8J2MUG6.1
#=GS A0A315VYC0_GAMAF/863-969 AC A0A315VYC0.1
#=GS A0A3P8SMR5_AMPPE/747-859 AC A0A3P8SMR5.1
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