LinkDB: APC_N_CC
Original site: APC_N_CC
Gene (5422) KEGG GENES (5422) Protein sequence (1740) UniProt (1734) SWISS-PROT (6) Protein domain (2) InterPro (1) NCBI-CDD (1) All databases (7164)
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#=GF ID APC_N_CC #=GF AC PF16689.9 #=GF DE Coiled-coil N-terminus of APC, dimerisation domain #=GF AU Coggill P;0000-0001-5731-1588 #=GF SE pdb_1deb #=GF GA 27.40 27.40; #=GF TC 27.50 34.00; #=GF NC 27.20 27.30; #=GF BM hmmbuild HMM.ann SEED.ann #=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq #=GF TP Coiled-coil #=GF RN [1] #=GF RM 10926498 #=GF RT Crystal structure of the amino-terminal coiled-coil domain of #=GF RT the APC tumor suppressor. #=GF RA Day CL, Alber T; #=GF RL J Mol Biol. 2000;301:147-156. #=GF DR INTERPRO; IPR032038; #=GF DR SO; 0001080; coiled_coil; #=GF CC APC_N_CC is the N-terminal, coiled-coil dimerisation domain of #=GF CC the adenomatosis polyposis coli (APC) tumour-repressor proteins. #=GF CC It plays a key role in the regulation of cellular levels of the #=GF CC oncogene product beta-catenin. Coiled-coil regions are binding #=GF CC repeats that in this case bind to the armadillo repeat region of #=GF CC beta-catenin [1]. #=GF SQ 1271 #=GS A0A7K8AWQ8_9CORV/6-57 AC A0A7K8AWQ8.1 #=GS A0A7L3MM59_9PASS/6-62 AC A0A7L3MM59.1 #=GS A0A7K9RGV0_9PASS/6-57 AC A0A7K9RGV0.1 #=GS A0A8J6FHE1_ELECQ/4-55 AC A0A8J6FHE1.1 #=GS K7ERC5_HUMAN/6-57 AC K7ERC5.2 #=GS A0A5F8H673_MONDO/98-149 AC A0A5F8H673.1 #=GS A0A5F9D6Y6_RABIT/4-55 AC A0A5F9D6Y6.1 #=GS A0A8C8I6H5_ONCTS/4-55 AC A0A8C8I6H5.1 #=GS A0A8C1B642_CYPCA/4-55 AC A0A8C1B642.1 #=GS S9YKL0_CAMFR/30-81 AC S9YKL0.1 #=GS A0A6J2LAQ5_9CHIR/4-55 AC A0A6J2LAQ5.1 #=GS A0A851MWU7_9DEND/6-57 AC A0A851MWU7.1 #=GS A0A674CKR8_SALTR/4-55 AC A0A674CKR8.1 #=GS A0A8C0KKC8_CANLU/4-55 AC A0A8C0KKC8.1 #=GS A0A8C5DGZ5_9TELE/2-53 AC A0A8C5DGZ5.1 #=GS A0A8I3RRG0_CANLF/4-55 AC A0A8I3RRG0.1 #=GS A0A8J4NNU6_EUDMI/6-57 AC A0A8J4NNU6.1 #=GS A0A8B8WWS3_BALMU/4-55 AC A0A8B8WWS3.1 #=GS A0A672NJB6_SINGR/4-55 AC A0A672NJB6.1 #=GS H2QRB5_PANTR/4-55 AC H2QRB5.1 #=GS A0A8C3N807_GEOPR/4-55 AC A0A8C3N807.1 #=GS A0A2K6C338_MACNE/30-81 AC A0A2K6C338.1 #=GS H0XHT6_OTOGA/6-57 AC H0XHT6.1 #=GS A0A484CKE7_PERFV/31-75 AC A0A484CKE7.1 #=GS S7PCR1_MYOBR/6-57 AC S7PCR1.1 #=GS A0A8D2IMQ9_UROPR/4-55 AC A0A8D2IMQ9.1 #=GS A0A2K5RKI0_CEBIM/4-55 AC A0A2K5RKI0.1 #=GS A0A7L2JI69_CINMU/6-57 AC A0A7L2JI69.1 #=GS A0A8K1LEI1_9PASS/1-38 AC A0A8K1LEI1.1 #=GS A0A6P6KZ14_CARAU/7-58 AC A0A6P6KZ14.1 #=GS A0A7K5DV17_POLCE/6-57 AC A0A7K5DV17.1 #=GS W5LI44_ASTMX/6-57 AC W5LI44.2 #=GS A0A7K6SCE0_9GRUI/6-57 AC A0A7K6SCE0.1 #=GS A0A8C3VNM9_9CETA/4-55 AC A0A8C3VNM9.1 #=GS A0A8C5K8W5_JACJA/8-59 AC A0A8C5K8W5.1 #=GS A0A6J2W4Q7_CHACN/7-58 AC A0A6J2W4Q7.1 #=GS H0XI22_OTOGA/4-55 AC H0XI22.1 #=GS A0A8C8A4G8_9STRI/6-57 AC A0A8C8A4G8.1 #=GS A0A7K4RPH2_COLPI/6-57 AC A0A7K4RPH2.1 #=GS A0A553MW93_9TELE/68-119 AC A0A553MW93.1 #=GS A0A7J7YV46_PIPKU/4-55 AC A0A7J7YV46.1 #=GS A0A493TYQ4_ANAPP/4-55 AC A0A493TYQ4.1 #=GS A0A8C4M7A0_EQUAS/4-55 AC A0A8C4M7A0.1 #=GS A0A3P8UAS3_AMPPE/4-55 AC A0A3P8UAS3.1 #=GS A0A835TNL9_9PASS/28-79 AC A0A835TNL9.1 #=GS A0A287DA74_ICTTR/6-57 AC A0A287DA74.1 #=GS A0A7K8HV68_9CORV/22-67 AC A0A7K8HV68.1 #=GS A0A452FZ37_CAPHI/4-55 AC A0A452FZ37.1 #=GS A0A671F4N9_RHIFE/1-38 AC A0A671F4N9.1 #=GS D3Z3K9_MOUSE/21-72 AC D3Z3K9.1 #=GS A0A7J7YVU6_PIPKU/4-55 AC A0A7J7YVU6.1 #=GS A0A2I4DD68_9TELE/4-55 AC A0A2I4DD68.1 #=GS A0A8C9Q1V1_SPEDA/4-55 AC A0A8C9Q1V1.1 #=GS A0A091IQM6_EGRGA/6-57 AC A0A091IQM6.1 #=GS A0A7L4E4J1_HIRRU/6-57 AC A0A7L4E4J1.1 #=GS A0A850XFD2_PIACA/6-57 AC A0A850XFD2.1 #=GS A0A452FZQ4_CAPHI/4-55 AC A0A452FZQ4.1 #=GS A0A8V5GQI2_MELUD/4-55 AC A0A8V5GQI2.1 #=GS A0A672M9K1_SINGR/4-55 AC A0A672M9K1.1 #=GS A0A6J3EHR4_AYTFU/4-55 AC A0A6J3EHR4.1 #=GS APC_HUMAN/4-55 AC P25054.2 #=GS A0A6P7X1C6_9AMPH/14-65 AC A0A6P7X1C6.1 #=GS A0A6J3FSM1_SAPAP/6-57 AC A0A6J3FSM1.1 #=GS A0A0P7Z6T0_SCLFO/4-55 AC A0A0P7Z6T0.1 #=GS A0A8M1FU00_URSMA/6-56 AC A0A8M1FU00.1 #=GS W5LXB8_LEPOC/6-57 AC W5LXB8.1 #=GS A0A7N9APX8_9TELE/4-49 AC A0A7N9APX8.1 #=GS A0A8C5LSV9_9ANUR/4-55 AC A0A8C5LSV9.1 #=GS A0A8D0DAF7_SANLU/4-55 AC A0A8D0DAF7.1 #=GS A0A8D2JZM9_THEGE/4-55 AC A0A8D2JZM9.1 #=GS A0A3M0JJU4_HIRRU/6-57 AC A0A3M0JJU4.1 #=GS A0A4W6F6A0_LATCA/6-58 AC A0A4W6F6A0.1 #=GS A0A7J8I3B7_MOLMO/30-81 AC A0A7J8I3B7.1 #=GS A0A7K6FQA1_9CORV/6-57 AC A0A7K6FQA1.1 #=GS A0A6J3FR89_SAPAP/30-81 AC A0A6J3FR89.1 #=GS A0A3Q3CRJ4_HAPBU/6-57 AC A0A3Q3CRJ4.1 #=GS A0A3L8RT55_CHLGU/6-57 AC A0A3L8RT55.1 #=GS A0A7K8S9X9_9PASS/6-57 AC A0A7K8S9X9.1 #=GS A0A8C2X1K2_CYCLU/6-52 AC A0A8C2X1K2.1 #=GS A0A1U8CVI6_MESAU/4-55 AC A0A1U8CVI6.1 #=GS A0A8C5UAT4_9PASS/6-57 AC A0A8C5UAT4.1 #=GS A0A8C7F1X6_ONCKI/4-55 AC A0A8C7F1X6.1 #=GS A0A673AQT7_9TELE/4-55 AC A0A673AQT7.1 #=GS A0A6P4YVB0_BRABE/24-75 AC A0A6P4YVB0.1 #=GS A0A7K7UBW5_9CHAR/6-57 AC A0A7K7UBW5.1 #=GS A0A485PQG5_LYNPA/30-81 AC A0A485PQG5.1 #=GS A0A8D2D6S5_SCIVU/4-55 AC A0A8D2D6S5.1 #=GS A0A7J8EXG1_ROUAE/4-55 AC A0A7J8EXG1.1 #=GS A0A8B7W5Y7_CASCN/4-55 AC A0A8B7W5Y7.1 #=GS A0A7K9L4P8_9PASS/6-57 AC A0A7K9L4P8.1 #=GS A0A4X2LLZ1_VOMUR/1-52 AC A0A4X2LLZ1.1 #=GS A0A7F8K9X6_DELLE/30-81 AC A0A7F8K9X6.1 #=GS A0A6P6DGB9_OCTDE/4-55 AC A0A6P6DGB9.1 #=GS A0A7L2D2V3_CATFU/6-62 AC A0A7L2D2V3.1 #=GS A0A8C8A407_9STRI/6-57 AC A0A8C8A407.1 #=GS A0A5F8H8F1_MONDO/98-149 AC A0A5F8H8F1.1 #=GS A0A8V5GZ32_MELUD/6-57 AC A0A8V5GZ32.1 #=GS A0A8C5LFB1_JACJA/4-55 AC A0A8C5LFB1.1 #=GS A0A7K5C327_MOTAL/6-57 AC A0A7K5C327.1 #=GS A0A4Z2BAQ6_9TELE/6-57 AC A0A4Z2BAQ6.1 #=GS A0A8C6ZAE8_NOTPE/4-55 AC A0A8C6ZAE8.1 #=GS A0A7L4FEF3_9COLU/6-57 AC A0A7L4FEF3.1 #=GS A0A8J8YC77_CALJA/4-55 AC A0A8J8YC77.1 #=GS A0A3Q7UPB2_VULVU/125-176 AC A0A3Q7UPB2.1 #=GS H0UWJ7_CAVPO/4-55 AC H0UWJ7.2 #=GS A0A498MH18_LABRO/4-55 AC A0A498MH18.1 #=GS A0A851CCX7_CALVR/6-57 AC A0A851CCX7.1 #=GS A0A8C8SJ24_9SAUR/6-57 AC A0A8C8SJ24.1 #=GS A0A6J3A5M8_VICPA/4-55 AC A0A6J3A5M8.1 #=GS A0A7K7CK81_APHCE/6-57 AC A0A7K7CK81.1 #=GS A0A7K6CGS2_PTIVI/6-57 AC A0A7K6CGS2.1 #=GS A0A2R8ZEG0_PANPA/6-57 AC A0A2R8ZEG0.1 #=GS A0A8C3Z756_9TELE/4-55 AC A0A8C3Z756.1 #=GS A0A8C4GCM8_9TELE/6-56 AC A0A8C4GCM8.1 #=GS A0A3Q3AWD3_KRYMA/4-55 AC A0A3Q3AWD3.1 #=GS A0A226MHF4_CALSU/5-56 AC A0A226MHF4.1 #=GS A0A851US25_9PASS/6-57 AC A0A851US25.1 #=GS A0A3Q0D7B6_MESAU/4-55 AC A0A3Q0D7B6.1 #=GS A0A1S3T4L1_SALSA/6-57 AC A0A1S3T4L1.1 #=GS A0A8V0Y647_CHICK/4-55 AC A0A8V0Y647.1 #=GS A0A7J7YUQ9_PIPKU/4-55 AC A0A7J7YUQ9.1 #=GS A0A5F8GN92_MONDO/4-55 AC A0A5F8GN92.1 #=GS A0A8C4UI41_FALTI/6-57 AC A0A8C4UI41.1 #=GS A0A8M2B1L0_DANRE/4-55 AC A0A8M2B1L0.1 #=GS A0A7J6AK26_AMEME/4-55 AC A0A7J6AK26.1 #=GS A0A8J6GQU4_MICOH/6-57 AC A0A8J6GQU4.1 #=GS A0A8C4VHW9_9SAUR/4-55 AC A0A8C4VHW9.1 #=GS A0A8C4FK26_9TELE/4-55 AC A0A8C4FK26.1 #=GS A0A8C0KQ57_CANLU/4-55 AC A0A8C0KQ57.1 #=GS H9GCR7_ANOCA/4-55 AC H9GCR7.2 #=GS A0A5F9D2P6_RABIT/4-55 AC A0A5F9D2P6.1 #=GS A0A6J2M7H7_9CHIR/6-57 AC A0A6J2M7H7.1 #=GS A0A093BYP0_9AVES/6-57 AC A0A093BYP0.1 #=GS A0A8C6D609_MOSMO/4-55 AC A0A8C6D609.1 #=GS A0A7K7GTT6_ERIRU/6-57 AC A0A7K7GTT6.1 #=GS A0A673IEU3_9TELE/4-55 AC A0A673IEU3.1 #=GS A0A8C3QFZ7_9PASS/4-55 AC A0A8C3QFZ7.1 #=GS A0A2Y9JIN4_ENHLU/4-55 AC A0A2Y9JIN4.1 #=GS A0A8I5NR64_PAPAN/4-55 AC A0A8I5NR64.1 #=GS A0A2K5HSI3_COLAP/4-55 AC A0A2K5HSI3.1 #=GS A0A7K6HA66_9PASS/6-49 AC A0A7K6HA66.1 #=GS A0A7J7XDK5_MYOMY/6-57 AC A0A7J7XDK5.1 #=GS A0A7K9KET4_9PASE/6-57 AC A0A7K9KET4.1 #=GS A0A7J8BPH2_ROUAE/6-57 AC A0A7J8BPH2.1 #=GS A0A7R5K8X3_9PASS/4-55 AC A0A7R5K8X3.1 #=GS A0A6P8S7R5_GEOSA/11-62 AC A0A6P8S7R5.1 #=GS A0A8C8Z8M9_PROSS/6-57 AC A0A8C8Z8M9.1 #=GS A0A6J2LDI2_9CHIR/4-55 AC A0A6J2LDI2.1 #=GS A0A8B8X0T5_BALMU/4-55 AC A0A8B8X0T5.1 #=GS A0A8B7ZKN6_ACAPL/7-58 AC A0A8B7ZKN6.1 #=GS A0A7J6AKZ1_AMEME/7-58 AC A0A7J6AKZ1.1 #=GS A0A7N8WIS0_9TELE/4-55 AC A0A7N8WIS0.1 #=GS A0A850VCB7_9CORV/6-57 AC A0A850VCB7.1 #=GS A0A3Q3B5V2_KRYMA/6-57 AC A0A3Q3B5V2.1 #=GS A0A7L4MC48_GLAPT/6-57 AC A0A7L4MC48.1 #=GS A0A2K5CBF0_AOTNA/4-55 AC A0A2K5CBF0.1 #=GS A0A7L2LGM7_9SYLV/6-57 AC A0A7L2LGM7.1 #=GS A0A2K6GRI3_PROCO/4-55 AC A0A2K6GRI3.1 #=GS A0A8D2F010_THEGE/4-55 AC A0A8D2F010.1 #=GS A0A7J8EWJ1_ROUAE/4-55 AC A0A7J8EWJ1.1 #=GS A0A8B7IP09_9AVES/6-57 AC A0A8B7IP09.1 #=GS A0A6J3ECN6_AYTFU/4-55 AC A0A6J3ECN6.1 #=GS H3D6T3_TETNG/6-57 AC H3D6T3.1 #=GS A0A6P3HWK1_BISBI/1-33 AC A0A6P3HWK1.1 #=GS A0A8C6ZI92_NOTPE/4-55 AC A0A8C6ZI92.1 #=GS A0A6J1YKY4_ACIJB/30-81 AC A0A6J1YKY4.1 #=GS A0A2K6GA60_PROCO/6-57 AC A0A2K6GA60.1 #=GS A0A8J6KPJ3_MICOH/4-55 AC A0A8J6KPJ3.1 #=GS A0A2K6PXN4_RHIRO/6-57 AC A0A2K6PXN4.1 #=GS A0A2Y9JRK9_ENHLU/4-55 AC A0A2Y9JRK9.1 #=GS A0A8D2DDQ0_SCIVU/6-57 AC A0A8D2DDQ0.1 #=GS A0A7J7X9Z8_PIPKU/30-81 AC A0A7J7X9Z8.1 #=GS A0A6I9LFC6_PERMB/4-55 AC A0A6I9LFC6.1 #=GS A0A668VE59_OREAU/4-55 AC A0A668VE59.1 #=GS A0A8C2TDT8_COTJA/4-55 AC A0A8C2TDT8.1 #=GS A0A0A0B3B2_CHAVO/6-57 AC A0A0A0B3B2.1 #=GS A0A1S3WST2_ERIEU/4-55 AC A0A1S3WST2.1 #=GS A0A7K7SS15_9TYRA/6-57 AC A0A7K7SS15.1 #=GS A0A0Q3MJ87_AMAAE/6-57 AC A0A0Q3MJ87.1 #=GS A0A3Q2H5U9_HORSE/4-55 AC A0A3Q2H5U9.1 #=GS A0A6J3FR94_SAPAP/6-57 AC A0A6J3FR94.1 #=GS A0A8B8X2L3_BALMU/30-81 AC A0A8B8X2L3.1 #=GS A0A6I9LJ35_PERMB/4-55 AC A0A6I9LJ35.1 #=GS 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