#=GF ID   ATG19
#=GF AC   PF12744.11
#=GF DE   Autophagy protein Atg19, Atg8-binding
#=GF PI   ATG19_autophagy;
#=GF AU   Wood V;0000-0001-6330-7526
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Wood V
#=GF GA   25.00 25.00;
#=GF TC   32.00 25.70;
#=GF NC   24.10 23.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0159
#=GF RN   [1]
#=GF RM   16247502
#=GF RT   Autophagy: molecular machinery for self-eating.
#=GF RA   Yorimitsu T, Klionsky DJ;
#=GF RL   Cell Death Differ. 2005;12:1542-1552.
#=GF RN   [2]
#=GF RM   11430817
#=GF RT   Cvt19 is a receptor for the cytoplasm-to-vacuole targeting
#=GF RT   pathway.
#=GF RA   Scott SV, Guan J, Hutchins MU, Kim J, Klionsky DJ;
#=GF RL   Mol Cell. 2001;7:1131-1141.
#=GF RN   [3]
#=GF RM   17192412
#=GF RT   Atg19 mediates a dual interaction cargo sorting mechanism in
#=GF RT   selective autophagy.
#=GF RA   Chang CY, Huang WP;
#=GF RL   Mol Biol Cell. 2007;18:919-929.
#=GF RN   [4]
#=GF RM   19236009
#=GF RT   ATG systems from the protein structural point of view.
#=GF RA   Noda NN, Ohsumi Y, Inagaki F;
#=GF RL   Chem Rev. 2009;109:1587-1598.
#=GF DR   INTERPRO; IPR024543;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Autophagy is generally known as a process involved in the
#=GF CC   degradation of bulk cytoplasmic components that are
#=GF CC   non-specifically sequestered into an autophagosome, where they
#=GF CC   are sequestered into double-membrane vesicles and delivered to
#=GF CC   the degradative organelle, the lysosome/vacuole, for breakdown
#=GF CC   and eventual recycling of the resulting macromolecules. In
#=GF CC   contrast to autophagy, however, the Cvt pathway is a highly
#=GF CC   selective process that involves the sequestration of at least
#=GF CC   two specific cargos that are resident vacuolar hydrolases,
#=GF CC   aminopeptidase I (Ape1) and alpha-mannosidase (Ams1). These
#=GF CC   proteins are sequestered within a double-membrane vesicle,
#=GF CC   termed a Cvt vesicle. The Cvt vesicle is fairly consistent in
#=GF CC   size, and is much smaller than the autophagosome, being 140-160
#=GF CC   nm in diameter. The prApe1 is sequestered within either Cvt
#=GF CC   vesicles or autophagosomes, depending on the nutrient
#=GF CC   conditions, and delivered to the vacuole. Autophagy and the Cvt
#=GF CC   pathway are topologically and mechanistically similar and share
#=GF CC   most of the same machinery. The Ape1 complex is ultimately
#=GF CC   enwrapped within either Cvt vesicles or autophagosomes at the
#=GF CC   perivacuolar PAS. The receptor protein Atg19 binds to the Ape1
#=GF CC   complex through the prApe1 propeptide to form the Cvt complex in
#=GF CC   the cytosol. In the absence of Atg19, prApe1 can form an Ape1
#=GF CC   complex, but does not localise at the PAS. Atg19 is a peripheral
#=GF CC   membrane protein with differing binding sites for both Ape1 and
#=GF CC   Ams1. The Atg8-binding region in the yeast proteins is this very
#=GF CC   C-terminal residues [3].
#=GF SQ   32
#=GS J8PWV8_SACAR/163-407      AC J8PWV8.1
#=GS ATG34_YEAST/163-412       AC Q12292.1
#=GS J7RRG9_KAZNA/175-412      AC J7RRG9.1
#=GS A0A1G4J3Q2_9SACH/304-551  AC A0A1G4J3Q2.1
#=GS A0A1S7HEL6_9SACH/267-449  AC A0A1S7HEL6.1
#=GS A0A376B680_9ASCO/180-272  AC A0A376B680.1
#=GS A0A1E5R0F0_9ASCO/176-358  AC A0A1E5R0F0.1
#=GS K0KQT3_WICCF/270-560      AC K0KQT3.1
#=GS A0A7H9B896_ZYGMR/243-507  AC A0A7H9B896.1
#=GS G0W6A4_NAUDC/703-912      AC G0W6A4.1
#=GS A0A1X7R6L5_9SACH/143-407  AC A0A1X7R6L5.1
#=GS G8BMN5_TETPH/141-398      AC G8BMN5.1
#=GS A0A0C7NEU8_9SACH/271-514  AC A0A0C7NEU8.1
#=GS A0A1G4JJF0_9SACH/297-540  AC A0A1G4JJF0.1
#=GS A0A7H9HSI9_9SACH/232-471  AC A0A7H9HSI9.1
#=GS H2ARX1_KAZAF/267-525      AC H2ARX1.1
#=GS C5DNC2_LACTC/272-509      AC C5DNC2.1
#=GS G0W3W6_NAUDC/170-261      AC G0W3W6.1
#=GS Q757I4_ASHGO/342-561      AC Q757I4.2
#=GS G0W3W6_NAUDC/275-440      AC G0W3W6.1
#=GS J5PDA7_SACK1/168-412      AC J5PDA7.1
#=GS A0A4C2E3S6_9SACH/270-455  AC A0A4C2E3S6.1
#=GS I6NDE5_ERECY/439-684      AC I6NDE5.1
#=GS A0A1E3NZL2_WICAA/268-511  AC A0A1E3NZL2.1
#=GS ATG19_YEAST/195-415       AC P35193.1
#=GS I2H5K3_TETBL/243-335      AC I2H5K3.1
#=GS A0A1G4M9T9_LACFM/266-505  AC A0A1G4M9T9.1
#=GS G0V9K5_NAUCC/177-418      AC G0V9K5.1
#=GS A0A1V2L3H9_CYBFA/235-438  AC A0A1V2L3H9.1
#=GS Q6CTN9_KLULA/338-596      AC Q6CTN9.1
#=GS G8ZTZ3_TORDC/228-462      AC G8ZTZ3.1
#=GS A0A1S7H9E3_9SACH/269-449  AC A0A1S7H9E3.1
J8PWV8_SACAR/163-407                 ............c-VMISEDNPD....LVEFFSHCKTDVQLEEFYEG...............YKV...YEK...LLQKFNGKKK.E.LFSfld.............entpVPEID..SVKQIVSYE.EPKEKKRETSA....P...K....DQSLRVEVG.HQDNSIHFTLCNNTNA.IVPGD..CTFE..FFNSASEV.FS..........IR--.--MGP.HELGIKGQKEL.CYfpSLP.IPLV.DYT.------.........IKVRN..KAGDII.FTGKCDKSNEIA.......LK.TPL...........---..--......STLSig...giHILQDPCDIFH.ADA.fSSFDESSVMSTPHTGEAS.DADDSAYTSSRSFTWEEI..........................................................
ATG34_YEAST/163-412                  ............c-IILPEDKPE....LIKFFSKFETSVQLQEVYEG...............YKV...YEK...LLQKFGGQKK.R.MESfln.............entpMSGAE..AIKQINISE.ELKEKGERLTT....P...N....DPLLHVEVS.NEDNSLHFILYNKTNI.IIPGN..CTFE..FSSQISEV.FS..........IK--.--MGP.HEIGIKGQKEL.WFfpSLP.TPLS.NYT.------.........MKVVN..QDGETI.LVGKCADSNEIT.......LK.SPL...........ASF..ST......GSFQtg...sfHTLQDPTNVFR.ADA.lSSPDESSIMSTPFLGETD.EVYNSGSTLSRPFTWEEI..........................................................
J7RRG9_KAZNA/175-412                 .............VIEVSKKNND....LFEFFNNILTEDQLKDLKHG...............FEK...YTQ...WISLYNNDEG.K.LE-....................-EHLK..TLQDFSTFF.STKDNSDFVKY....P...-....---ISLRIF.PKELNICFELQNSFGV.AVPKG..LALMiyYRDGTLDK.TS.........tYKVD.IS---.HGVGPHLTKTF.RR..FKR.EFGP.EFS.VGNVTR.........VQIIS..DRSQIL.YTGHQDAFAEES.......DP.QSR...........VFN..FTvv..ddIAFA.......ENNNDND----.TAS..YKDNDNDIISTSISNTAN.DDDNH-------------tvtedadfndy...............................................
A0A1G4J3Q2_9SACH/304-551             ............l-IDIPESQDQ....VFSFFANIKSVTELSAMIEK...............CAK...FDA...LEQQVGGDWT.S.LENavklm..........assttSFETL..-AEDSGSQL.ASVDANRDEVS....D...E....DDLILVELI.KKDHLISFKLHNRGIH.PVSSG..LKLV..FQ-YFETA.DAn........pVKCT.LHMGP.HEFQADSHKIL.NF..NYR.GLID.NFS.TSHSCK.........IDLVD..QDDTVV.FTGSSAGSSTLV.......LR.PAA...........MPD.vQT......SVYL.......EAQSSTS----.-GL..DSLNAHDVISTTATNEES.TKFSSY------------dsevedyd..................................................
A0A1S7HEL6_9SACH/267-449             lrasnprrerrrr----------....--------------------...............---...---...----------.-.---....................-----..---------.-----------....-...E....LSLLEILVT.RRDNLLTFTVHNIGKC.TVPAGsiLRLS..LSDGSKLP.ST..........FSVE.GCLGP.HELAPGGKRML.NQ..QIP.SSFP.QHL.ASNEPR.........IFLFDgtNNERAL.YAGSASTLFDST......fQL.RPLefa.....stsQHD..CK......P---.......-----------.LSP..LIKEEEELVSSSNTNDEY.SLCSE-------------lsndsnesnvsnwedy..........................................
A0A376B680_9ASCO/180-272             .............IIDISDKHNQ....LFEFFSAIKDEQELLDIMNK...............YKS...YDK...LVEELDVLKN.E.RQK....................KSISS..DTAASSSNI.MDKEQKS--CE....A...-....---------.----------------.-----..----..--------.--..........----.-----.-----------.--..---.----.---.------.........-----..------.------------.......--.---...........---..--......----.......-----------.---..------------------.------------------ekdcqdvssstntitntst.......................................
A0A1E5R0F0_9ASCO/176-358             ...........vf--DISDKDKD....LFDFFSKLDTVEKLRGVMNK...............VVN...YDE...LLIQYEALLP.KtLPKsvf.............ptpsAKTAE..SFSS-STLT.SSKDGFSTTPN....F...SgklgNPGIYVDFGiKNKKEMVFKILNSSNNiTIPTN..CILN..FNFVRKST.HK.........mVKCY.LQMSKsQEVKPLDSFKI.NF..NH-.----.---.------.........-----..------.------------.......--.---...........---..--......----.......-----------.---..------------------.------------------vfqdgdflnesehfevkimhksk...................................
K0KQT3_WICCF/270-560                 ...........pi--DSKEYESK....IVEFVSKYNDVSKLSKILSK...............IQT...YDH...LLSLTDNDEV.L.LS-....................-TMVE..SFIESNKNQ.SIENK-SS--I....S...K....KPNLSIEIS.QIDQTLIFHLQNKSSL.LTPKN..LTLV..MKIVNKHE.GEgdi....dnvTKFN.LSIGP.HSIYPNGHKRL.YY..NLN.GIYEsNFKlFDNKFT.........IELFD..EFNKLF.ALGICINGSGLV......eLN.DDL..........nVLE..KL......SNID.......IDDKDED---E.IDE..DGSSE-QILQQTNSNSNS.NSNS--------------dsnssssqfvtpsnstfitdqifqskedlidiesktdslestetadsasttespkssi
A0A7H9B896_ZYGMR/243-507             .............VIDIPEEEKE....LFEMFGDID---KLKEIAKG...............YKS...YKK...WVED-HGGEE.K.VSDilr..............nslNAHTN..DSASSNSFN.RPKTVKRRYHT....AskvK....HSPVKVEIT.RKDTTVFFKLFNRSKN.NIPGG..FSLV..YSVSDSEV.PElsqnaehtfsEICN.LTMGP.HELLVDHTKTL.RF..NFY.PRVA.ETL.NFEKGD.........IKIVD..PNNRTV.YSSTKCELSGKSht...ffLK.KLH..........dISD.fSNs....lQTYV.......DTTSSPET-CQ.LLE..KEQYSDGVISSNVTNDDE.TIHSGSS-----------qdsnwdey..................................................
G0W6A4_NAUDC/703-912                 ..........let-------DDE....THDFISTLKTSEDLKKVVNG...............YPK...FKE...WRYIGGKDES.E.IDErf................ssKDNMI..AQVSINHEL.ENIKKPEEFLN....-...-....STALEVTME.RRYKDIKFTLTNRGKS.DLPGN..SKFV..VQYSIEHHgVAh........vADVT.LDMGP.HKLLIGSKKHL.LW..SPP.CPIH.NGI.-----V.........VDVVElsTEDGFV.FYSGKVHDNNFE.......LS.TPA...........---..--......----.......-----------.---..------------------.------------------lsyehlevneqyynslekrkqvnll.................................
A0A1X7R6L5_9SACH/143-407             ............y-FDIDPQNNE....LFEFYSNIKSSEDLENIMKS...............YQK...YQN...WIQKFNNDEK.Y.LENqlenmlvl...tkhpivpslSKETS..SKKLDSMEKqNIPNKNTNTHN....Nn.nN....NYPFTLTIY.EKDLNFCFKLKNNTDI.YFPNK..LNIV..TNLDG-GS.YV..........IS--.---VP.HGIGPRNQRVF.TR..FKR.EFGS.DCQ.ISDFMY.........FQIKD..IDEKTVlYEGIRSKFDNEQs.....iFKlRSV...........NHL.tLS......GINL.......EKLQKHNSTPS.PPSvrSSVDAGDIISTTISSNLN.ES----------------tsgrtfdeydflse............................................
G8BMN5_TETPH/141-398                 .............IIDIPESNSK....VYDFFSKIETVSELEEVMNG...............YLK...WKE...VEQRDNVCDQ.E.INN....................KNEVV..GHPSVRSDI.SSKPGTDDLVN....E...N....QVVLAVEIT.KSDYLIEFNVIHEGEK.DLPSD..LRLA..YHDES---.--..........IKINdLPLGK.HPLKAGRNKTI.KC..NTF.NLLN.TTT.GGVTSSnnhttrqnyIYIYD..PSDDSV.QYIANIATPQTKv....ylEK.APMl.........sAHN.lQKye..mlSSPS.......LLKEQNN---N.TQS..KSEDDNDIISTTVTNTTL.SHNPRNTKSTNSRRISDW..........................................................
A0A0C7NEU8_9SACH/271-514             .............IIDIPERNAA....VFNYFSKVETESELVELIQN...............HEN...YQE...LLHKVGGDKS.K.LDD...................aIDQFL..EPKYSDASS.GSLDASVATAR....E...D....DNLIVVEVS.KREHVISFRLWNKGPD.SVPSG..LKLV..FRCFEPPS.TV.........pIKCT.LHMGP.HEFQMGHYKTL.NF..NCR.GMID.HFL.MQNTYQ.........VDLVD..HEDQVV.YTGCSQGEPTIC.......LR.PLV..........lMGI..QE......SVYA.......EAREDDTSLVT.TVH..DDSDDHDIISNTVSNDEN.AKYYSD------------leeydfl...................................................
A0A1G4JJF0_9SACH/297-540             .............VIDIPERSSK....VFDFFSNVQSESDLAALVGD...............HEK...YQL...LLSKLEGDEE.K.LTQ....................LVETHldTKATSKNLI.TSLDASVETAH....D...A....DNLIEVEMS.KREHVISFKLLNKGPD.SVCNG..LKLV..FR-YFEAN.SAv........pIKCT.LHMGP.HEFQRDHYKTL.NF..NCR.GLID.YFS.MANTCQ.........IDLVD..HDDQVV.FTGISRGGSRLL.......LR.PPM...........MIG.iQE......SVYS.......EARESHD--LE.TGS.qDDRDDRDIISNTMTNEDT.KDSELED-----------ydflsd....................................................
A0A7H9HSI9_9SACH/232-471             .............VIDIPGERKD....LFDMFANL---ENLDAVIHG...............YSM...YKK...WTEKYDDDK-.-.IDE...................iLKNAS..VKPAVKTSR.SNKRTK---SS....I...K....PAGLVVEMT.QKDNALIFHIYNRDKV.AVPGG..LTLS..GSLIGDAE.RG..........GDWE.LPMGP.HELLPGCHKVL.KY..NCH.AETF.NFP.TSATSK.........ITLVD..EHKNVS.YEGVTNFQPGSHf.....tLH.HSG...........AKP.eQD......LVLI.......NDANSNANALQ.LLE..KDDSDSVISSSTVTNDND.TSQSVSN--HESFDWED-y.........................................................
H2ARX1_KAZAF/267-525                 ............f-IDIDPKNRR....LFEYFSKIASEADLEKLLSN...............SQK...YEG...LLQRFDNDET.L.LL-....................-SELS..HLSLNNSDT.SSIKHEEP--T....E...M....GIPFELKVY.EKDLNVCFELSNGTDT.YFSEN..LYLL..IHYISSEN.EI..........WKTK.IDI-C.HGIGPKSKRIFtKF.kSFFeKKGG.DFS.IEDFGF.........FEIKD..GADRLL.FSTQGSKLVPCNngtdlmfH-.--Lvaky...nnltEIN.lRKl....eNFKS.......EETIKLKEAFT.YDN..ENVESDDVISTTITNDVGfENNDSDN-----------efeeydflse................................................
C5DNC2_LACTC/272-509                 .............IIDIPDRNAR....VFDFFSKIKTEEQLAQLINH...............YEK...YEN...LLAQVSGDDA.K.LQ-....................--EAV..ALILSPCKT.NSLDASIETAH....E...E....EDLIDVQMG.KRDHVISFKLNNRGPR.PVSSG..LRLV..FQ-YFEPR.NAn........pVKCT.LHMGP.HEFQKDSYKTL.NF..NCR.GLIE.NFS.LGNPCK.........IDLVD..QDDDVI.FTGSSSGGPNMC.......LK.QPI...........MFD.iQQ......SVYS.......EAREVPD----.LEA..DSIEDQDIISNTVTNEGS.QHASRDD-----------selddydf..................................................
G0W3W6_NAUDC/170-261                 ............f-LDIPIGNKN....LISFFQNLKSEDDLEKLVDE...............YEL...YQD...LKKQYDGHMGiE.ML-....................--LDE..ALERRRFET.ESKDSRNKTQL....T...T....QK-------.----------------.-----..----..--------.--..........----.-----.-----------.--..---.----.---.------.........-----..------.------------.......--.---...........---..--......----.......-----------.---..------------------.------------------mdevlaktaelekfi...........................................
Q757I4_ASHGO/342-561                 .ifapdisvaaat----------....---LFSQVHDVKDLERIASQ...............CAA...YES...LVPRFGASAE.E.LE-....................-----..------RKL.SSLPPK---AT....E...D....EFGISVTVS.RVDFALTFRLRNYTTD.AIPSS..SSLV..FSHHPVGG.SS..........HTRT.MSIGP.HELPPGSSKQL.NI..CYP.---H.QTS.DGDPYS.........LSLVS..PAGTAL.YSGKASSMPADIll...acP-.--GgtpassaafnaMYT..NQ......SSAS.......-----------.---..------------------.------------------vpapvvnapfrqsnspvmpsdeeydllsdsd...........................
G0W3W6_NAUDC/275-440                 ............t-IKIPKSDGF....LNEFYSKITTTEKLQDLAIG...............YNW...YKE...WIQGCDNNEH.L.V--....................-----..-----SSAI.Y--QGKEYMKG....K...M....QCEVSIIVQ.RNETTWDVTLENISDD.PLPKG..MKLV..IESYESPK.QKr.......pvVVLS.TNIGG.--FPPSHADEL.EL.gPTK.NLNE.DLR.KYLRSV.........IKFVT..NEGEVV.YS----------.......--.---...........---..--......----.......-----------.---..------------------.------------------tvfeed....................................................
J5PDA7_SACK1/168-412                 .............YVVLPEDKPE....LVEFFSHLKTSEQLQEIYNG...............YRV...YET...LLQKFDGQKE.K.MHSflh.............egtsVPEGE..SMEQIALFE.EPKEKKEALAT....P...D....DRSLRVDVN.HEDNSLHFILYNNADL.IVPGN..CTFE..FSSSASKV.YS..........IK--.--MGP.HEIGPKGQKEL.WYfpSLS.APLV.DYT.------.........VKIIN..QNGDVI.FIGKCTESNEVT.......LK.SAL...........---..--......SSFStg...sfHTLQDPNNVFR.ADA.lSSFDESSVMSSPFPNEID.EIYDSGSTLNRPFTWEEI..........................................................
A0A4C2E3S6_9SACH/270-455             ..snkkprfrpel----------....--------------------...............---...---...----------.-.---....................-----..---------.-----------....-...-....-FSLEVTVT.RRDDLLTFNMYNNGKR.SLPGG..CVLI..LSNCGSPF.SSt........kTKIE.IHLGS.HELRRGDRKFL.HK..QIS.DGLA.ADC.----VR.........IDILSgkNKERVL.YTGFASCLLNTCv.....kLK.PPK...........PSD..SP......LSPSptatlasSAATGNQTSYKpLSS..LAKEDEGVISSSVTNDEY.SLCS--------------dsgeesnwedy...............................................
I6NDE5_ERECY/439-684                 ............t-IEIPPEQSD....VYEVLLKMQNEGTLASVVHE...............AED...YQR...IIKRFDTSAS.E.IFErlgryeelllmlpdgnydklKSLIE..EHLKCNNKA.PISPADSAMKS....P...S....SSEILVEVC.DIDYVVTFKLTNHTDE.VLPDN..MKLL..LNYFPDDG.EA..........LKYC.IFMGP.HKIAPDESKLL.NL..NHH.GSIK.RLF.AEGKYQ.........LDLLD..QNDILL.YTTKLTNEAKVS.......MK.P--...........---..--......----.......-----------.---..------------------.------------------ltretvdgclldfevvdglvnsmeklsasskfsadtlarde.................
A0A1E3NZL2_WICAA/268-511             ........lgake------YETA....IVDFVKNYDTVDKLKQLKEK...............LAT...FNN...LLELTDNNGQ.L.LT-....................---TI..VQSYVDSQK.FGKEES-----....K...N....TEGLTVQVS.QVARTIVFHLQNKGAV.STPKN..LNLL..FTCQGNEN.AL..........TKFS.LSMGP.HSIHSNGHKRL.YY..NTN.GIGF.NLS.--DKFT.........IELIG..DDNQVY.ASGVCTDGSGLIkle.dpkLK.NSS...........SVE..KG......ESFGs.....sSSSTSSNEAFM.TPS.sSTLIEQQVASEIMENKEE.EDTTKDS-----------sdkvdddtvvqd..............................................
ATG19_YEAST/195-415                  ............t-IDIPEDRSE....LVNFFTELKTVKQLEDVFQR...............YHD...YER...LSQECDS---.K.---....................-----..--TEIASDH.SKKETKIEVEP....P...N....ERSLQITMN.QRDNSLYFQLFNNTNS.VLAGN..CKLK..FTDAGDKP.TT.........qI---.IDMGP.HEIGIKEYKEY.RY.fPYA.LDLE.A--.---GST.........IEIEN..QYGEVI.FLGKYGSSPMIN.......LR.PPS...........---..RL......SAES......lQASQEPFYSFQ.IDT.lPELDDSSIISTSISLSYD.GDDNE-----KALTWEE-l.........................................................
I2H5K3_TETBL/243-335                 ............v-LNIPEEKKE....LFDFFSKVQDTSTLSNIQHG...............FET...YQR...WLEKVGGKES.E.IEK....................LLDVH..SIMQQELRQ.ETIKTDNKTNI....S...S....TDSERV---.----------------.-----..----..--------.--..........----.-----.-----------.--..---.----.---.------.........-----..------.------------.......--.---...........---..--......----.......-----------.---..------------------.------------------mknnlkgqle................................................
A0A1G4M9T9_LACFM/266-505             .............VIDIPEYDEK....VFKFFSNIKNEPELSRVVEF...............YEK...YSS...LLEQVGGDES.K.LTD...................aVQLAS..SVNSSTATI.AS--PIEALEG....E...E....DDLIEVDMS.KKDQVISFKLCNRSTK.SISSG..LKLV..FQ-YFEKG.NSi........pIKCN.LHMGP.HEFQAGNYKIL.NF..NYR.GVID.NFS.PFNRCQ.........IDLVD..QNDQLI.FTGASEGSSNLI.......LK.PPM...........MAS.fQK......TVYS.......EADTARE---S.KSS..ESLEDEDIISTTVTNDDF.KQSS--------------nydseiddyd................................................
G0V9K5_NAUCC/177-418                 ...iyvkndlyqk----------....----INELLSKTKINDIIHG...............YEK...YTEwigLCQDNEDEVR.K.IL-....................TNNNE..ETATIQVDD.EPKNSFINDATslsaS...M....VPVITMNYQ.IKDFHVEFTLHNCGTS.TLSGG..LNFV..FQYQTDSG.NN.........iIEHQ.IDMGP.HDLKPDCKKIL.KF..MSL.NMIN.TNL.--EILS.........VNVVG..IDGRVI.YVGKKDAEKNNQf.....nLT.HPIls......aehL--..-EtneeffSVYS......fHQKQEPS----.---..EPVDTTDVISTTITNDNA.T-----------------kftweeyd..................................................
A0A1V2L3H9_CYBFA/235-438             ............y-VDIPFSDPKfatlLLELFKEKTSAEDIVKMKQG...............YEK...YLK...LVDIVGEENE.D.---....................-----..KLVEIVQKG.IPEPVSL---E....S...D....TPSVIVSIV.KMDSSIAFHLTNKSST.EIPSN..LKLR..LLAENKQG.NV.........vLK--.LSVGP.HPIQPGGFKRL.FY..NTN.NLSF.DFN.NDTLYT.........VELVD..KSGVAY.ALGSSENTNGTV.......--.---...........---..--......----.......-----------.---..------------------.------------------hlyklseddededeedtddipsdyeilsst............................
Q6CTN9_KLULA/338-596                 .............IIEVGQQNKA....MFDFFAEIKTESELEKLMQDaiswriakqwygediYEKlerYQN...MMQENAQKER.E.---....................-----..-------NE.SSDEATMNTQG....S...S....NPSLRVEMF.QKGHLLTFKLFNDGDE.TIPNG..LKLV..FQCEQKGR.VAt........pIKCN.LQVGP.DELQPGNYKIL.NF..NYR.GTLE.EFS.FEQPCK.........IDLID..VREQVV.YTTEQSTVPGSSv....fhLK.PPVck......mlpMGD..RR......NIPC.......NEDEDPDVQYT.LTS..PSQSDTDVISSSVTDQEE.EEEEEEEEEE--------eeeeeent..................................................
G8ZTZ3_TORDC/228-462                 .............VIDIADDRKD....LFDLFSKM---ENLEEIVHG...............FRL...YKK...WTEKLSEEKI.E.---....................-----..-GILSGEEF.SAKNRRFEVAK....P...G....--KLEVELK.KKDKAIIFQMRNTGAS.TVAGG..LTLV..YSTFKEDD.NLda......snVTCE.LPMGP.HELLPGNSKML.KF..NYF.GVLS.DIS.METKSQ.........IALVD..SEKNFI.FKGTNSGRAGSHf....ilNS.TGL...........ASDgiAG......DLPL.......LN--RRD---S.LQL.lEKDDSDSVISSTVTNDNE.TLHSVSDQ--E-------tsnwdey...................................................
A0A1S7H9E3_9SACH/269-449             .asklgrerhrre----------....--------------------...............---...---...----------.-.---....................-----..---------.-----------....-...-....LSLLEIFVT.RRDNLLTFTVHNVGKC.TVPAGsvLRLS.lFHDEKLP-.ST..........FSIE.GCLGP.HELAPGGRRVL.NQ..QIS.SSFP.RNL.ASNEPR.........IFLFDgtNSEHVL.YAGSASTLFDSTf.....qLR.PPEfa......nssQHD..CK......PLSP.......LIKED------.---..-----VEVVSSSNTNDEY.SLCSELSND---------snesnisnwedy..............................................
#=GC seq_cons                        ..............l-Istpppc....lh-FFuplpo.ppLpclhpt...............app...Ypp...llpphsspcp.c.l.........................h...th.t.spph.pshptp.thtt........p....ps.lpVpls.ccDpslpFpLhNpusp.slPss..hpLh..hp..tptt.ts..........hchp.lphGP.HcltssspKhL.pa..sh..s.ht.ph....t..p.........lplls..ppspsl.atGtpss.st.t.......hp..sh......................................pt.t...........t.pppplhSsshosp...p...................t.t.....................................................
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