#=GF ID   Adeno_52K
#=GF AC   PF03052.19
#=GF DE   Adenoviral protein L1 52/55-kDa
#=GF AU   Mifsud W;0000-0002-9805-6461
#=GF SE   Pfam-B_2151 (release 6.4)
#=GF GA   25.00 25.00;
#=GF TC   44.20 42.50;
#=GF NC   19.20 17.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   8627769
#=GF RT   The complete DNA sequence and genomic organization of the avian
#=GF RT   adenovirus CELO. 
#=GF RA   Chiocca S, Kurzbauer R, Schaffner G, Baker A, Mautner V, Cotten
#=GF RA   M; 
#=GF RL   J Virol 1996;70:2939-2949.
#=GF RN   [2]
#=GF RM   8709283
#=GF RT   Interaction of the adenovirus L1 52/55-kilodalton protein with
#=GF RT   the IVa2 gene product during infection. 
#=GF RA   Gustin KE, Lutz P, Imperiale MJ; 
#=GF RL   J Virol. 1996;70:6463-6467.
#=GF RN   [3]
#=GF RM   9733823
#=GF RT   Encapsidation of viral DNA requires the adenovirus L1
#=GF RT   52/55-kilodalton protein. 
#=GF RA   Gustin KE, Imperiale MJ; 
#=GF RL   J Virol. 1998;72:7860-7870.
#=GF DR   INTERPRO; IPR004292;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The adenoviral protein L1 52/55-kDa is expressed in both the
#=GF CC   early and late stages of infection which suggests that it could
#=GF CC   play multiple roles in the viral life cycle.  The L1 52/55 kDa
#=GF CC   protein interacts with the viral IVa2 protein and is required
#=GF CC   for DNA packaging [2][3]. L1 53/55-kDa is required to mediate
#=GF CC   stable association between the viral DNA and empty capsid [2].
#=GF SQ   75
#=GS A0A1Y0B6F7_9ADEN/44-244  AC A0A1Y0B6F7.1
#=GS PKG3_ADE12/45-246        AC P36715.1
#=GS A0A4Y5G371_9ADEN/96-302  AC A0A4Y5G371.1
#=GS A0A191ULN3_9ADEN/85-291  AC A0A191ULN3.1
#=GS Q71BX8_ADE01/25-147      AC Q71BX8.1
#=GS A0A163HI15_9ADEN/43-242  AC A0A163HI15.1
#=GS A0A1J0FAP2_9ADEN/25-227  AC A0A1J0FAP2.1
#=GS A0A1T1H7S3_OCELI/1-92    AC A0A1T1H7S3.1
#=GS H9AAP4_9ADEN/46-247      AC H9AAP4.1
#=GS T1UHA6_9ADEN/42-243      AC T1UHA6.1
#=GS Q5GFB5_ADE04/62-263      AC Q5GFB5.1
#=GS A6MLX3_9ADEN/62-263      AC A6MLX3.1
#=GS Q9YUR3_9ADEN/21-215      AC Q9YUR3.1
#=GS A0A097IW89_9ADEN/48-249  AC A0A097IW89.1
#=GS PKG3_ADES1/21-226        AC A9CB88.1
#=GS A0A191ULU4_9ADEN/90-296  AC A0A191ULU4.1
#=GS A0A0A7JTI3_9ADEN/21-229  AC A0A0A7JTI3.1
#=GS Q89727_ADE40/53-254      AC Q89727.1
#=GS X5M4W1_9ADEN/72-278      AC X5M4W1.1
#=GS G9B6K0_9ADEN/13-206      AC G9B6K0.1
#=GS Q32UI0_9ADEN/52-253      AC Q32UI0.1
#=GS U5NEI5_9ADEN/87-293      AC U5NEI5.1
#=GS I3PMM8_9ADEN/74-275      AC I3PMM8.1
#=GS A0A5J6SG81_ADE01/68-269  AC A0A5J6SG81.1
#=GS B9A5X9_9ADEN/43-244      AC B9A5X9.1
#=GS DNBI_ADE12/64-188        AC P36704.1
#=GS A0A076FTF2_9ADEN/30-235  AC A0A076FTF2.1
#=GS B2VQE9_9ADEN/43-244      AC B2VQE9.1
#=GS A0A223PYR1_9ADEN/36-242  AC A0A223PYR1.1
#=GS A0A7H0S536_9ADEN/34-239  AC A0A7H0S536.1
#=GS E0YC62_9ADEN/84-289      AC E0YC62.1
#=GS A0A1L5LC28_9ADEN/72-278  AC A0A1L5LC28.1
#=GS A0A6H1TF82_9ADEN/68-270  AC A0A6H1TF82.1
#=GS A0A1X9RIV9_9ADEN/31-231  AC A0A1X9RIV9.1
#=GS Q9QM77_9ADEN/85-291      AC Q9QM77.1
#=GS A0A7R7FRG8_ADEB7/31-235  AC A0A7R7FRG8.1
#=GS C7SRT3_9ADEN/52-253      AC C7SRT3.1
#=GS PKG3_ADE02/68-269        AC P03262.1
#=GS A0A6M6AAP8_9ADEN/53-254  AC A0A6M6AAP8.1
#=GS A0A0M4MET7_9ADEN/44-245  AC A0A0M4MET7.1
#=GS J9Z410_9ADEN/68-269      AC J9Z410.1
#=GS LEAD_ADE02/23-142        AC P03263.1
#=GS A0A1B1SL26_9ADEN/90-295  AC A0A1B1SL26.1
#=GS A0A516UYJ9_9ADEN/68-269  AC A0A516UYJ9.1
#=GS Q2KSB9_9ADEN/57-258      AC Q2KSB9.1
#=GS Q2KSC5_9ADEN/25-137      AC Q2KSC5.1
#=GS B5SNR8_ADE41/49-250      AC B5SNR8.1
#=GS A0A2Z4QJM2_9ADEN/28-228  AC A0A2Z4QJM2.1
#=GS P87555_ADEC2/25-227      AC P87555.1
#=GS Q83899_ADEO7/32-238      AC Q83899.1
#=GS A0A1J0MUL6_9ADEN/97-299  AC A0A1J0MUL6.1
#=GS A0A6N3IR65_9ADEN/32-235  AC A0A6N3IR65.1
#=GS A0A1P8SW67_9ADEN/72-275  AC A0A1P8SW67.1
#=GS A0A516UYP3_9ADEN/25-147  AC A0A516UYP3.1
#=GS A0A0K1DBT9_ADEE2/36-238  AC A0A0K1DBT9.1
#=GS A0A5H2X2P0_9ADEN/61-264  AC A0A5H2X2P0.1
#=GS A6MLX0_9ADEN/15-138      AC A6MLX0.1
#=GS A0A0M5L3X4_9ADEN/46-247  AC A0A0M5L3X4.1
#=GS E7CH35_9ADEN/110-323     AC E7CH35.1
#=GS PKG3_ADEG1/70-273        AC Q64753.1
#=GS Q9III1_ADEF1/14-210      AC Q9III1.1
#=GS E9KLA0_9ADEN/92-298      AC E9KLA0.1
#=GS H9AAV9_9ADEN/76-277      AC H9AAV9.1
#=GS A0A1U9AL11_ADE04/22-137  AC A0A1U9AL11.1
#=GS B6SBM4_9ADEN/21-216      AC B6SBM4.1
#=GS O11416_9ADEN/21-227      AC O11416.1
#=GS Q997I2_ADEB4/32-238      AC Q997I2.1
#=GS Q9WF15_ADE17/43-244      AC Q9WF15.1
#=GS A0A4P8PIN3_9ADEN/59-234  AC A0A4P8PIN3.1
#=GS Q6QPE7_9ADEN/60-261      AC Q6QPE7.1
#=GS A0A191ULI3_9ADEN/85-291  AC A0A191ULI3.1
#=GS A0A5F2P0F9_9ADEN/60-262  AC A0A5F2P0F9.1
#=GS A0A096ZH18_9ADEN/85-291  AC A0A096ZH18.1
#=GS A0A1D8QMB5_9ADEN/70-276  AC A0A1D8QMB5.1
#=GS U5NEE5_9ADEN/62-265      AC U5NEE5.1
A0A1Y0B6F7_9ADEN/44-244             .............larlha-----------HPDN..HPRVCVKRDAAEAYIPRE..NLF...RDRSGE....ePEGSRDLKYKAGRQL...R..T..GMprKRVLTEGDF..eVDERS....GISSAKAHMEAADLVRAYEQTVKQEANFQKSFNNHVRTLISREETTLGLMHLWDFAEAYSQNPA...SKTLTAQLFLIVQHLQDEGIFREAFL.SIAEPE......GRWMLDLLNILQSIVvQERQLSLPEKVAAVN.........
PKG3_ADE12/45-246                   ...............iarl-----GAHSPER---..HPRVQLARDSRVAFVPRQ..NMF...RDNSGE....eAEEMRDCRFRAGREL...R..R..GFnrERLLREEDF..ePDEHS....GISSARAHVSAANLVTAYEQTVTEERNFQKSFNNHVRTLIAREEVAIGLMHLWDFVEAYVHNPA...SKPLTAQLFLIVQHSRDNETFRDAML.NIAEPQ......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
A0A4Y5G371_9ADEN/96-302             ..................m-GPPVCGIAAGADVD..EIRMQERERARRGAVPET..NLFktsRDSLPQ.....NDYEREAMYRSGQAL...T..L..DR..RRVLTARDFeygEGEDP....SFTPGANHLRAAELKRAAEQTAFGEEMRNSCHQTRLRTALLRPELPAGIYYLYDFVQTYVDHPD..gRVKLNPQLMLVAQHAG-NTMLAQRLW.TIAEDK......NAWLRDLIEMAYMIV.NDPYLTTEQQLAAVC.........
A0A191ULN3_9ADEN/85-291             ..................l-GPPVCGLAAGADVD..EIRMRERESGRRGAIPET..NLFkasREAVPQ.....NDYDREAMYRSGQAI...S..V..NR..GRVLTADDFaydEGQDP....SFTPGANHLRAAELKRAAEQTAFGEELRNSCHQARLRTALTRPELPAGIYYLYDFVQTYVDHPD..gRVKLNPQLVLVAQHAG-NTMLAQRLW.SIAEDK......NAWLRDLIEMAYMIV.NDPYLSTEQQLSAIC.........
Q71BX8_ADE01/25-147                 ..........evpatgrtl---------------..------------------..---...------.....---------------...-..-..--..---------...-----....VLAFVKTCAVLAAVHGLYILHEVDLTTAHKEAEWEFEPLAWR--VWLVVFYFG-----------...CLSLTVWLLEGSYGGSDHHAARAQSP.DVRARR......SELDDNIAQMGAVHGlELPRRQVRRELLQV-y........
A0A163HI15_9ADEN/43-242             .............larvvs----------GGPER..HPRVQVKRDASEAYVPRQ..NVL...RDHPGT....eGEEMRDLRYRAGRHM...R..V..PK..NRVLRDVDF..eAEPLT....GISPARAHLEAANLATAYEQTAREEANFQKTFNNNVRTLVAREEVTIGLMHLWDFTEAYVSNPS...SKTLTAQLFLIAQHSRDEGVFKESLL.TLAEPE......SQWLVDLINILQSIIvQERGMRVPEKVAAIN.........
A0A1J0FAP2_9ADEN/25-227             ..................m-ARIQGGAAPET---..HPRVLMKQEASEAYIPPS..NVF...RDNEGE....eAEGMRHLKFEAGRTL...R..G..SHgaRRVLGERDF..eKDPRN....GISPAEAHLKSADLVTAYEQTVNEEVNFQTSFNNNVRTLIAREEVVVGLMHLWDFVQAYLENPI...SKALTAQLFLIVQHCRDEGVLRESLL.NIAEPE......SRWLVDLLNLLQTIVvQERGLSVGEKVAAIN.........
A0A1T1H7S3_OCELI/1-92               ...................---------------..------------------..---...------.....---------------...-..-..--..---------...-----....-----------------------------------MRTLVAREEVAIGLMHLWDFVSALEQNPN...SKPLMAQLFLIVQHSRDNEAFRDALL.NIVEPE......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
H9AAP4_9ADEN/46-247                 ..............larlg------AHVP---ER..HPRVQLARDSRAAYVPRQ..NLF...RDASGE....eGEELRDCRFRAGREL...RagL..DR..ERLLRAEDF..eAEEGR....GVSPARAHLAAANLVTAYEQTVKEERSFQQSFNNHVRTLVAREEVAIGLMHLWDFVEAFVHNPS...SKALTAQLFLIVQHSRDNELFRDALL.NIAEPE......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
T1UHA6_9ADEN/42-243                 ...............larl-----GAPSPER---..HPRVQLQKDVRPAYVPAQ..NLF...RDRSGE....ePEEMRDCRFRAGREL...RegL..DR..QRVLRDEDF..ePNEQT....GISPARAHVAAANLVTAYEQTVKQERNFQKSFNNHVRTLIAREEVALGLMHLWDLAEAIVQNPD...SKPLTAQLFLVVQHSRDNEAFREALL.NIAEPE......GRWLLELINILQSIVvQERSLSLAEKVAAIN.........
Q5GFB5_ADE04/62-263                 ...............larl-----GASSPER---..HPRVQMKRDAREAYVPKQ..NLF...RDRSGE....ePEEMRAARFHAGREL...RrgL..DR..KRVLRDEDF..eADELT....GISPARAHVAAANLVTAYEQTVKEESNFQKSFNNHVRTLIAREEVTLGLMHLWDLLEAIVQNPT...SKPLTAQLFLVVQHSRDNETFREALL.NITEPE......GRWLLDLVNILQSIVvQERGLPLSEKLAAIN.........
A6MLX3_9ADEN/62-263                 ...............larl-----GASSPER---..HPRVQMKRDAREAYVPKQ..NLF...RDRSGE....ePEEMRAARFHAGREL...RrgL..DR..KRVLRDEDF..eADELT....GISPARAHVAAANLVTAYEQTVKEESNFQKSFNNHVRTLIAREEVTLGLMHLWDLLEAIVQNPT...SKPLTAQLFLVVQHSRDNETFREALL.NITEPE......GRWLLDLVNILQSIVvQERGLSLSEKLAAIN.........
Q9YUR3_9ADEN/21-215                 ..................m-SSPAISGEPESPLQ..PFTEQMEKE--ESKVPQN..NLF...RDGNVN.....-EHLRDIRYYSGKSV...Q..L..DG..DQKLKGSDF...GEDYP....CFSKGENFMKAAKLKRDADYTETYEVSAQDADNNFYKVMLMRPETLFGLYYFESIIKNIMSDPS...--NTVFLRRLCALAVEWNGRLKGFIP.ELPDDR......HEWLRDLITLLAAIC.-RSCVTVDEQVAAIN.........
A0A097IW89_9ADEN/48-249             ................lar---L-GAHSPER---..HPRVQLKKDSSEAYVPSR..NTF...RERSGE....ePEEMRDCRFRAGREL...RkgM..DR..DRLLRAEDF..ePQERT....GVSAARAHVAAADLVTAYEQTVKEEMNFQKSFNNHVRTLIAREEVAIGLMHLWDFLEAYVQNPT...SKPLTAQLFLIVQHSRDNETFRDALL.NIAEPE......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
PKG3_ADES1/21-226                   .................np--ELHCGIAGTGGLEeqLRSKQREDRFHKACPPAV..DLN...RDDTQL....yGEGERDLRLKSSACV...Q..L..DR..TPV-TPEDF...VPDDM....G-SRAIRQMEAAKLVRNGQHTRDVERWQHDTYCSHLTQLLVRPLTSLGVMYLADFLNTFVELPP...NHTLTMQLVTIINHTS-EPTLRRLLK.DIGEKDaeghlkNEWLLQLLSIIEMIFkDEPS-----------erarltall
A0A191ULU4_9ADEN/90-296             .................gg--PPVCGLAAGADID..EIRMRERESGRRGAVPET..NLFkasRDALPQ.....NDYDREAMYRAGQAL...S..V..NR..RRVLTADDFaygEGQDP....SFTPGANHLRAAELKRASEQTAFGEEMRNSCHQTRLRTALMRPELPAGIYYLYDFVQTYMDHPD..gRVKLNPQLVLVAQHAG-NTMLAQRLW.SIAEEK......NAWLRDLIEMAYMIV.NDPYLSTEQQLAAVC.........
A0A0A7JTI3_9ADEN/21-229             .................pa--PSNCGIAVRSDEElqARKEQRADHSGASAGPKRpkDVF...RDAEPR.....MAEERDLAYKAGKAI...T..V..DM..GKVLCPDDF...SPDMP....ASSPAERHIQAAELKRNATHTDNLEEWAHDTFMMTCRQLLRQHSTRLGVIYLSDFLHSYVESPP...KHELAVQMAAIQQHTQ-NAVIRRALQ.RAGEKNekgestQKWFLDLMRVIEMIV.-EEERHVGAQLAALN.........
Q89727_ADE40/53-254                 ...............larl-----GAPSPER---..HPRVQLKKDSRQAYVPPQ..NLF...RDRSGQ....ePEEMRDRRFYAGQEL...R..A..GFnrQRVLRAEDF..ePDEHS....GISPARAHVSAADLVTAYEQTVNEERNFQKSFNNHVRTLVAREEVAIGLMHLWDFMEAYVQNPS...SKPLTAQLFLIVQHSRDNEAFREAML.NIAEPE......GRWLLDLVNILQSIVvQERSLSLADKVAAIN.........
X5M4W1_9ADEN/72-278                 .................ee--PPTCGVAAGAGLD..TTRMYEREARRRGAVPET..NLFkdtRDRVPQ.....NDYEREMMYRSGQTL...R..V..DG..RRVLRPEDFvpeAEADP....TFSPASNHLRAAELKRAARQTAFGEEMRVCRHQTRLRTALARPELRAGLYYLYDFVQTYVEHPD..gRVKLNPQLVLVAQHAG-NTLLAQRLW.AIAEER......NAWLRDLIEMAYVIA.NDAYLSAEQQLAALC.........
G9B6K0_9ADEN/13-206                 ..............tstie------GAQAESPLQ..PYTEQMEKE--ESKVPQN..NLF...RDGNVN.....-EHLRDLKYYSGKSV...E..L..DS..QTRLQAGDF...REEFP....CFSRGENFMKAATLKRDADYTESYEVSAQDADNNFYKMILMRPETIFGLYYFENILKNLIKDPT...--NTTLVRRLCTVAVEWSGRLKGFIP.ELTDER......HGWLRDLITLLAAIC.-RSCVTVEEQVAAIN.........
Q32UI0_9ADEN/52-253                 ...............larl-----GAPSPER---..HPRVQLKKDSREAYVPQQ..NLF...RDRSGE....ePEEMRASRFNAGREL...RhgL..DR..RRVLRDEDF..eVDEVT....GISPARAHVAAANLVSAYEQTVKEERNFQKSFNNHVRTLIAREEVTLGLMHLWDLMEAIIQNPT...SKPLTAQLFLVVQHSRDNEAFREALL.NITEPE......GRWLYDLINILQSIIvQERSLGLAEKVAAIN.........
U5NEI5_9ADEN/87-293                 .................dg--PPVCGLSAGADMD..EIRMRERESARRGAIPEL..NLFkanKEILPQ.....NDYERESMYRAGHAL...S..V..DR..NRVLTARDFaygEGEDP....SFTPGANHLRAAELKRAAEQTAFGEEMRNSCHQTRLRTALLRPELPAGIYYLYDFVQTYVDHPD..gRVKLNPQLVLVAQHAG-NTMLAQRLW.AIAEEK......NAWLRDLIEMAYMIV.NDPYLNTEQQLSALC.........
I3PMM8_9ADEN/74-275                 .................la---PTCGIASGSGID..EFRSYERDVHRAAQVPES..NLFkdpRSVIPQ.....NDYEREAMYRSGQAI...D..V..NR..QRVLTPSDF...EGD-P....RFNPAVNHLKAAELKRQAEQTSFNEEFRNVSHQAKLRTALTRRELKAGIFYLYDFVQTYMDHPD..gRVALNPQLVLVAQHAG-NSILAQRLW.AIAEDR......NAWLRELIEMAYMIV.NDPYLSVQQQLSAIC.........
A0A5J6SG81_ADE01/68-269             ...............larl-----GAPSPER---..HPRVQLKRDTREAYVPRQ..NLF...RDREGE....ePEEMRDRKFHAGREL...R..H..GLnrERLLREEDF..ePDART....GISPARAHVAAADLVTAYEQTVNQEINFQKSFNNHVRTLVAREEVAIGLMHLWDFVSALEQNPN...SKPLMAQLFLIVQHSRDNEAFRDALL.NIVEPE......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
B9A5X9_9ADEN/43-244                 ...............larl-----GAPSPER---..HPRVQLQKDVRPAYVPAQ..NLF...RDRSGE....ePEEMRDCRFRAGREL...RegL..DR..QRVLRDEDF..ePNEQT....GISPARAHVAAANLVTAYEQTVKQERNFQKSFNNHVRTLIAREEVALGLMHLWDLAEAIVQNPD...SKPLTAQLFLVVQHSRDNEAFREALL.NIAEPE......GRWLLELINILQSIVvQERSLSLAEKVAAIN.........
DNBI_ADE12/64-188                   .......vmkveissadra---------------..------------------..---...------.....---------------...-..-..--..---------...----F....MLMFVKACAVFASLHGLYLLNEVYLAASHQKADGKINT-TWQ--LPFVLFLFC-----------...CIATTVWILE-SENGEGDGAPRPACP.DFSTRG......AETGNQGVQPGAVHGiSQREKHVRGDSAQV-d........
A0A076FTF2_9ADEN/30-235             ................cpe---THCGIAATGGLEdqLRSKQREDRQPKPAAPLV..DYH...RDDKKI....yGEGERDLLYKSSACV...S..L..DD..S-PISSEDF...EPDDM....-GSRAMRHMEASKLVRNGQHTRDVERWQYDTFKSHVFQLLGRPFTSLGVLYLSDFLNTFVELPP...NHALTMQLVTILNHTS-EPTLRRILK.DIGEKDgeghlkNEWLLQLVNIIEMIFkDEPSDK--T------rltail...
B2VQE9_9ADEN/43-244                 ...............larl-----GAPSPER---..HPRVQLQKDVRPAYVPAQ..NLF...RDRSGE....ePEEMRDCRFRAGREL...RegL..DR..QRVLRDEDF..ePNEQT....GISPARAHVAAANLVTAYEQTVKQERNFQKSFNNHVRTLIAREEVALGLMHLWDLAEAIVQNPD...SKPLTAQLFLVVQHSRDNEAFREALL.NIAEPE......GRWLLELINILQSIVvQERSLSLAEKVAAIN.........
A0A223PYR1_9ADEN/36-242             ................qna---INVGIASINDEEasLRRNQRDDRLPKAKIPIT..DIF...HDEEPK.....MAEERDLMYNASKYI...K..I..DT..QKKLNPESF...KPDFP....SSNAAARHIEAAELYRNGCHTRDLEKWTYDTFISHVKQLICRPNISLGLTYLDDFIQTYIELNN...HSELMYQLIAILNHIT-EPTLKRLIS.NIAQKDkkgaltQQWLIDLITCLYLIF.-RDEQTVSEKLSAL-l........
A0A7H0S536_9ADEN/34-239             ..........esvglsrvq-----------ADPQ.tHPRVQMKKDAAEAYVPPR..NVF...RDDPGL....eGESLRDLQFKAGKHM...R..L..DR..ERVLTDRDFetsAEDST....GISPARAHLEAANMLTAYEQTVRQEKNFQATFNNNVRTLLTRQEVTLGLMHLWDFISAYLERCS..pHKSLTSQLMLIAQHCREDGILRDSLL.NICEPE......SRWLVDLIDVLQSIIvQERQLKISEKVAAIN.........
E0YC62_9ADEN/84-289                 ................aea---PQCGLAAGAGLD..GVRMGEREAARRAAVPET..NLFkapKETLPE.....SDYERDLMYRSGQAL...E..V..DR..RRVLRPEDFa.sEGPDP....SFTPAANHLRAAELKRAAEQTAFGEEMRNQCHQTRLRTSLLRPELAAGLYYLYDFVQTYVEHPD..gRVALNPQLVLVAQHAG-NSMLAQRLW.AIAEDK......NAWLRDLIEMAYMIA.NDPYLGTEQQVAALC.........
A0A1L5LC28_9ADEN/72-278             ..................a-GPPVCGLASGAGLD..AVRMAERDAHRRGAVQET..NLFkdtRDRVPQ.....NDYEREMMYRSGQMI...E..V..DG..QRVLRPEDFvpmSEEDP....TFSPAANHIRAAELKRAARQTQFGEEMRNCRHQTRIRTALLRPELGAGIYYLYDFVQTYLEHPD..gRVKLNPQLVLVAQHAG-NTLLAQRLW.AIAEDR......NAWLRDLIEMAYVIV.NDPYLTTEQQVAAVC.........
A0A6H1TF82_9ADEN/68-270             ...........larlycdp-------------ET..HPRCVMKRDGCVAAVPQK..NVL...RDACDPpggseAEDLRHARYAAGRDI...A..L..DP..ESVIRDDDF..vPCDRS....GISRARAQLQAADLKTAFEQTVRQESNFQRSFNATVRGIVSRDDVLVGLMHLWDFVEAYVGNPT...SKALNAQLFLIAQHSRDEGLFREALL.NICDRE......SKWLLDLINVLQTIVvQERHLSAAEKVAAVN.........
A0A1X9RIV9_9ADEN/31-231             .............larlqt--------SP---EQ..HPRVAIKKDASEAYVPEQ..NLF...RDNEGQ....eFEEIRDLKFNSGKEM...CcgL..NR..KKLLKDEDF..eLDEKT....GISPARAHISAADLVTAYEQTVKEEMNFQKAFNNQVRVLISREEVMIGLLQLWDFIEAFKINPK...SRCLTSQLLLIAQHIKGPGVFRETFL.NINEPE......SRWLYDLINLLQSIVvQERSLKLPEKVAAIN.........
Q9QM77_9ADEN/85-291                 ..................l-GPPVCGLAAGADVD..EIRMRKRESGRRGAIPET..NLFkasREAVPQ.....NDYDREAMYRSGQAI...S..V..NR..GRVLTADDFaydEGQDP....SFTPGANHLRAAELETPGRADRVREELRNSCHQTRLRTALTRPELPAGIYYLYDFVQTYVDHPD..gRVKLNPQLVLVAQHAG-NTMLAQRLW.SIAEDK......NAWLRDLIEMAYMIV.NDPYLSTEQQLSAIC.........
A0A7R7FRG8_ADEB7/31-235             ...............cegc-----VGIASKPDEQtkFRRSQRDDRLPKAQIPLE..DIH...SDPEPK.....MAEERDLQYKASNVI...Q..L..DE..NKVLKSDDF...KPDFP....SSSPAQRHIEAAKIKRDGDYTRSLEQWSHDTFISHCKQLLTRPCTSLGIIYLDDFLQTYLEHSN...SSSLNFQLFTLINHVN-EPMLKRLLK.SISDKNek.gfvNQWLIDLITCMYLIL.-RDEKDLDNQISAL-l........
C7SRT3_9ADEN/52-253                 ...............larl-----GAPSPER---..HPRVQLKKDSREAYVPQQ..NLF...RDRSGE....ePEEMRASRFNAGREL...RhgL..DR..RRVLRDEDF..eVDEVT....GISPARAHVAAANLVSAYEQTVKEERNFQKSFNNHVRTLIAREEVTLGLMHLWDLMEAIIQNPT...SKPLTAQLFLVVQHSRDNEAFREALL.NITEPE......GRWLYDLINILQSIIvQERSLGLAEKVAAIN.........
PKG3_ADE02/68-269                   ...............larl-----GAPSPER---..HPRVQLKRDTREAYVPRQ..NLF...RDREGE....ePEEMRDRKFHAGREL...R..H..GLnrERLLREEDF..ePDART....GISPARAHVAAADLVTAYEQTVNQEINFQKSFNNHVRTLVAREEVAIGLMHLWDFVSALEQNPN...SKPLMAQLFLIVQHSRDNEAFRDALL.NIVEPE......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
A0A6M6AAP8_9ADEN/53-254             ...............larl-----GAPSPER---..HPRVQLKKDSRQAYVPPQ..NLF...RDRSGQ....ePEEMRDRRFYAGQEL...R..A..GFnrQRVLRAEDF..ePDEHS....GISPARAHVSAADLVTAYEQTVNEERNFQKSFNNHVRTLVAREEVAIGLMHLWDFMEAYVQNPS...SKPLTAQLFLIVQHSRDNEAFREAML.NIAEPE......GRWLLDLVNILQSIVvQERSLSLADKVAAIN.........
A0A0M4MET7_9ADEN/44-245             ...............larl-----GAPSPER---..HPRVQLVRDARQAFVPKQ..NLF...RDRSGQ....eAEEMRDCRFRAGREL...R..AgfDR..ERLLRAEDF..ePDERS....GVSPARAHVSAANLVSAYEQTVNEERNFQKSFNNHVRTLIAREEVTIGLMHLWDFVEAYVQNPA...SKPLTAQLFLIVQHSRDNETFRDAML.NIAEPE......GRWLLDLINILQSIVvQERGLSLADKVAAIN.........
J9Z410_9ADEN/68-269                 ...............larl-----GAPSPER---..HPRVQLKRDTREAYVPRQ..NLF...RDREGE....ePEEMRDRKFHAGREL...R..H..GLnrERLLREEDF..ePDART....GISPARAHVAAADLVTAYEQTVNQEINFQKSFNNHVRTLVAREEVAIGLMHLWDFVSALEQNPN...SKPLMAQLFLIVQHSRDNEAFRDALL.NIVEPE......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
LEAD_ADE02/23-142                   ........kvevpatgrtl---------------..------------------..---...------.....---------------...-..-..--..---------...-----....VLAFVKTCAVLAAVHGLYILHEVDLTTAHKEAEWEFEPLAWR--VWLVVFYFG-----------...CLSLTVWLLEGSYGGSDHHAARAQSP.DVRARR......SELDDNIAQMGAVHGlELPRRQV--------lrh......
A0A1B1SL26_9ADEN/90-295             .................ee--PPSCGMAVGATLD..PTRMYERDAARKGAIPEV..NLFkakPDTVPQ.....GDYDRDMMYRSGQVV...Q..L..DR..NRVLRPEDFa.aDAGDP....TFSPAVNHMKAAELKRASEQTAFGEEMRNVCHQTRIRTALSRPEVGAGIYYLYDFVQTYMEHPD..gRVKLNPQLVLVAQHAG-NTSLAQRLW.AIAEEK......NAWLRDLIEMAYMIV.TDPYLSIEQQVSAVC.........
A0A516UYJ9_9ADEN/68-269             ...............larl-----GAPSPER---..HPRVQLKRDTREAYVPRQ..NLF...RDREGE....ePEEMRDRKFHAGREL...R..H..GLnrERLLREEDF..ePDART....GISPARAHVAAADLVTAYEQTVNQEINFQKSFNNHVRTLVAREEVAIGLMHLWDFVSALEQNPN...SKPLMAQLFLIVQHSRDNEAFRDALL.NIVEPE......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
Q2KSB9_9ADEN/57-258                 ...............larl-----GAPSPER---..HPRVQLKKDSREAYVPQQ..NLF...RDRSGE....ePEEMRASRFNAGREL...RhgL..DR..RRVLRDDDF..eVDEVT....GISPARAHVAAANLVSAYEQTVKEERNFQKSFNNHVRTLIAREEVTLGLMHLWDLMEAITQNPT...SKPLTAQLFLVVQHSRDNEAFREALL.NITEPE......GRWLYDLINILQSIIvQERSLGLAEKVAAIN.........
Q2KSC5_9ADEN/25-137                 ..........elpatrraf---------------..------------------..---...------.....---------------...-..-..--..---------...-----....MLVLVQTAAVLAAIHGMHLMNELYLTSFDEKFQWKIE--AWR--LYLALYYVV-----------...CIGMTIFCLD---GGHADEPSREASP.DLGAAG......AELEDESAQAGAVQG.---PETLRSQVL---ra.......
B5SNR8_ADE41/49-250                 ...............larl-----GAPSPEH---..HPRVQLKRDARQAYVPPQ..NLF...RDRSGQ....ePEEMRDRRFHAGKEL...R..A..GFnsQRVLRAEDF..ePDKRS....GVSPARAHVSAADLVTAYEQTVNEERNFQKTFNNHVRTLVAREEVAIGLMHLWDFMEAYVQNPA...SKPLTAQLFLIVQHSRDNETFREAML.NIAEPE......GRWLLDLVNILQSIVvQERSLSLADKVAAIN.........
A0A2Z4QJM2_9ADEN/28-228             ............glarieg-------H---EPDK..HPRVCLKKDSSESYIPEK..NVF...RDHPGD....eMEQMRDMKYRSGKEI...Q..L..DK..MRVLTENDF..eIDPSS....RVSAARKHMEAADLVTAYEQTAKQEANFQKTFSNHIRVLISREEVNIGLMYLWDFIEAFVSNPS...SKTLNAQLFLIVQHSRDDGIFRDALL.SINAPE......SRWLLDLVNILQTIIvQERSLRTSEKVAAVN.........
P87555_ADEC2/25-227                 ..................l-ARLQGGAAPEL---..HPRVQMKQEAAEAYIPTS..NVF...RDNEGE....eAEGLRHLKYESGRLL...R..N..DHtsKRVLGERDF..eKDPQN....GISAAEAHLKSADLVTAYEHTVKAEVNFQTTFNNNVRTLIAREEVVIGLMHLWDFVEAFLENPV...SKALTAQLFLIVQHCRDEGVLRESLL.NIAEPE......SRWLVDLLNLLQTIVvQERGLAVGEKVAAIN.........
Q83899_ADEO7/32-238                 ..................e-FEPAVGISSKPSDEfnMRRSQRDDNLPKSQIPVV..DIL...HDKNPK.....MAEERDLMYKSSACI...K..L..DD..SKQLKTDMF...RPDFA....GTSPAQRHIEAAELKRNGSYTRSLEQWTHDSFISHVKQLLSRPFISLGITYLDDFLQTYLDHTE...SSSLNFQLFTLINHCS-ENTLKRILK.HISKKNeknqyvNQWLIDLITCIYLII.-RDEQNVTEQVNAL-l........
A0A1J0MUL6_9ADEN/97-299             ..................l-ARLQGGAAPEV---..HPRVQMKQEAAEAYIPAS..NVF...RDNEGE....eAEGLRHLKYESGRML...R..K..DHpsKRVLDERDF..eKSPEN....GISAAEAHLKSADLVTAYEHTVKAEVNFQTTFNNNVRTLIAREEVVIGLMHLWDFVEAFLENPV...SKALTAQLFLIVQHCRDEGVLRESLL.NIAEPE......SRWLVDLLNLLQTIVvQERSLAVGEKVAAIN.........
A0A6N3IR65_9ADEN/32-235             ...............ssss-----CGIAAPRSAVeaRVRFREDGKAPKARLPQV..DLF...RDPEPY.....MEEERDLRYRASGCL...N..L..PP..E-VMTEVDF...QPDEV....G-NRAIRQLEAAKLKRSGEFTRDAEKWQHDLFQSSVRQLLLRHNTPMGMLYLSDFFNTFVDAPP...SHALSMQHLTILNHVT-EPTLYRALK.EIDAKTkggrlkKEWLLHLLEVLHMIF.-KEERTVSGRLTAL-m........
A0A1P8SW67_9ADEN/72-275             ..................s-VPPTCGLAVGAGID..EARMRERDMGRKAAVPEI..NLFkesKDSLPH.....GDYDRDLLYEAGQGI...A..V..NR..RRVLTPEDF...ESEHP....DFSPAVNHLKAAEMKRAAEQTAFSEEMRNTRHQTRLRTAILRPELPAGIYYLYDFVQTYVEHPD..gRVKLNPQLVLVAQHAG-NSILGQRLW.AIAEDK......NSWLRDLIEMAYMIV.QDPNLSSEQKLSAVC.........
A0A516UYP3_9ADEN/25-147             ..........evpatgrtl---------------..------------------..---...------.....---------------...-..-..--..---------...-----....VLAFVKTCAVLAAVHGLYILHEVDLTTAHKEAEWEFEPLAWR--VWLVVFYFG-----------...CLSLTVWLLEGSYGGSDHHAARAQSP.DVRARR......SELDDNIAQMGAVHGlELPRRQVRRELLQV-y........
A0A0K1DBT9_ADEE2/36-238             ..........eglarlthd------------PET..HPRAVLKKDASEAYVPKR..NLI...REEDGE....yAETVRDLRLRAGSHM...R..L..DS..QRVLTDHDFe.tEPAAP...tSVSPARAHLEAANLLTTYQQTVKEEKNFQQSFNNHVRTLVARQEVTVGLMHLWDFVEALTENPS...SRSLTSQLFLILQHSRDDGVFRESLL.HIGDPD......GRWLLDLINVLHTIVvQERNLKLAEKVAAIN.........
A0A5H2X2P0_9ADEN/61-264             ................niv---PSCGIASGAGID..NFRVLSRDINRRALVPET..NLFkssTDVVPQ.....NDYEREHMYKAGTAI...S..V..NP..NRVLKPDDF...NGEAP....DFNPAINHIKAANLKTAANQTARQEELRNICHQSRLRTALTRLEIKAGLYYLYDFVATYVENPD..gRVALNPQLVLVAQHAG-NSMLAERIW.SIADDK......NTWLRELIEMAYMII.NDPTLTTDQQLSAIC.........
A6MLX0_9ADEN/15-138                 rgmavdvmevemptarrtf---------------..------------------..---...------.....---------------...-..-..--..---------...-----....VLVFIQAATVLATLHGMHVLHELYLGSFDEEFQWEVES--WR--LHLVLYYVV-----------...VVGLALFCLD---GGHADEPAREAGP.DLGANG......SESEDEGAQAGAVQG.---PETLRSQVS---gqr......
A0A0M5L3X4_9ADEN/46-247             ..............larlg------AHVP---ER..HPRVQLARDSRAAYVPRQ..NLF...RDGSGE....eGEELRDCRFRAGREL...RagL..DR..ERLLRAEDF..eAEEGR....GVSSARAHLAAANLVTAYEQTVKEERSFQQSFNNHVRTLVAREEVAIGLMHLWDFVEAFVHNPG...SKALTAQLFLIVQHSRDNELFRDALL.NIAEPE......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
E7CH35_9ADEN/110-323                .......lpptrgsgeldr------------AVA.rHPRVALKRDTQVSDVAPD..NLF...REDLSGgv.geREGLRDLHYRAGHEIlesG..L..DR..ERVLSGYDF...EQPVSggpaGPSPGHAHVRAADLATAYQQTVRQERSFQQTFNHTLRTLLAREETRVGLMHLWDFAQALRDNPQ...SRALTAQLFLITQHCRDEGVFREALL.GLAEPE......SRWLFDLLDILQSIVvQEQRLTTEERVAAIN.........
PKG3_ADEG1/70-273                   ..................e-GPVACGLAAGAGVD..EVRMRERDAARRATVPEI..NLFkarRDVVPN.....GDYERDLMYHSGQAI...D..I..DR..QRVLTPEDF...KGSEP....AFTPAVNHMRAAELKRAAEQTAFGEELRNTCHQTRIRTALLRPEIGAGIYYLYDFVQTYLEHPD..gRVKLNPQLVLVAQHAG-NTMLAQRLW.AIAEEK......NAWLRDLIEMAYMIV.NDPYLNTEQQLSAIC.........
Q9III1_ADEF1/14-210                 ............kldstpd----VGDMTSQ---Q..VYAEQLEKE--ESKVPQR..NLF...RDGSMN.....-DYVKDTTYYSGKAV...K..L..DP..RTRLVPDDF...REEFP....GFSAAVNHMKAAELKLDADSTERYEVSHQDTINNIIKSMVLRPETLMGVTYLQNILQR-LEDPN..gVDVALVMRHLYMLALNWDGELRNILT.EIGDKK......YEWLRDIVAMTHAIL.-NELHDVNEIVAAIN.........
E9KLA0_9ADEN/92-298                 .................gg--PPVCGLAAGADID..EIRMRERESGRRGAVPET..NLFkasRDALPQ.....NDYDREAMYRAGQAL...S..V..NR..RRVLTADDFaygEGQDP....SFTPGANHLRAAELKRASEQTAFGEEMRNSCHQTRLRTALMRPELPAGIYYLYDFVQTYMDHPD..gRVKLNPQLVLVAQHAG-NTMLAQRLW.SIAEEK......NAWLRDLIEMAYMIV.NDPYLSTEQQLAAVC.........
H9AAV9_9ADEN/76-277                 ..............larlg------AHVP---ER..HPRVQLARDSRAAYVPRQ..NLF...RDASGE....eGEELRDCRFRAGREL...RagL..DR..ERLLRAEDF..eAEEGR....GVSPARAHLAAANLVTAYEQTVKEERSFQQSFNNHVRTLVAREEVAIGLMHLWDFVEAFVHNPS...SKALTAQLFLIVQHSRDNELFRDALL.NIAEPE......GRWLLDLINILQSIVvQERSLSLADKVAAIN.........
A0A1U9AL11_ADE04/22-137             .......mevemptarrtf---------------..------------------..---...------.....---------------...-..-..--..---------...-----....VLVFIQAATVLATLHGMHVLHELYLGSFDEEFQWEVES--WR--LHLVLYYVV-----------...VVGLALFCLD---GGHADEPAREAGP.DLGANG......SESEDEGAQAGAVQG.---PETL--------rsqglra..
B6SBM4_9ADEN/21-216                 .............msppai-----EGTQPDSPLQ..AITEQMEKE--ESKVPQN..NLF...RDGNVN.....-EHLRDLKYYSGKSI...S..L..DP..ETRLRPSDF...KEEYP....CFSRGENYMKAATLKRDADYTESYEVSAQDADNNFYKMILLRPETIFGLYYVENILKNLIKDPT...--NTTLVRRLCTVAVEWSGRLKGFIP.ELTDER......HGWLRDLITLLAAIC.-RSCTSVEEQVAAIN.........
O11416_9ADEN/21-227                 ..................q-CPIDCGIANKGDGAfsMRKQQRDDRVPVSAAPPV..DVF...RSPSPK.....MSEERDLMYHSGNAI...D..I..DT..NRKLEVKDF...SPDIP....GSSAANRHIQAAELYRNAKYTKDVETWAHDTFIATCRQLLRRPAVPLGLLYLTDFLHNYVQHPP...RHELAIQFVAIQQHVE-NSVLRRLLS.RISEKNdkgqltQQWFMDLVQVLEMIV.-EEETSVSTQLSAIC.........
Q997I2_ADEB4/32-238                 .................nk--NFNVGIASKHDEEttLRETQRNDKIPKSKIHKI..DVF...RDEEPK.....MAEERDLIYNASNHI...S..L..NL..DKKLEPEMF...KPDFP....GTNAAQRHIEAAEVHRNGNHTRDLEQWCHDTFVSHAKQLLLRPNLSLGMTYLDDFLQTYLEHSN...SSELTFQLITLLSHTT-EPTLRRLLS.SVSQKDskgnfkQQWLIDLVTCLYLII.-RDEQNINERLSAL-l........
Q9WF15_ADE17/43-244                 ...............larl-----GAPSPER---..HPRVQLQKDVRPAYVPAQ..NLF...RDRSGE....ePEEMRDCRFRAGREL...RegL..DR..QRVLRDEDF..ePNEQT....GISPARAHVAAANLVTAYEQTVKQERNFQKSFNNHVRTLIAREEVALGLMHLWDLAEAIVQNPD...SKPLTAQLFLVVQHSRDNEAFREALL.NIAEPE......GRWLLELINILQSIVvQERSLSLAEKVAAIN.........
A0A4P8PIN3_9ADEN/59-234             .............yetggd---------------..------------------..-TV...RDGQFN.....-EHQRDMIQQSGRQL...T..V..SP..VDLDKEEDY...EELAP....GMSQSVCRLKAEKMKNLTKHTDEREYNKSRQDYNQIHMLVSHSQVKMGLMYISDLLSAICNSSTpqnNYQLAAQMSVIAMHCQGEVISDLFMSgTLGEAC......NAWFVNIVHSLNTIV.NLSKLSAKKATHAI-l........
Q6QPE7_9ADEN/60-261                 ...............larl-----GASSPER---..HPRVQMKRDAREAYVPKQ..NLF...RDRSGE....ePEEMRASRFHAGREL...RrgL..DR..KRVLRDEDF..eADELT....GISPARAHVAAANLVTAYEQTVKEESNFQKSFNNHVRTLIAREEVTLGLMHLWDLLEAIVQNPT...SKPLTAQLFLVVQHSRDNETFREALL.NITEPE......GRWLLDLVNILQSIVvQERGLPLSEKLAAIN.........
A0A191ULI3_9ADEN/85-291             ..................l-GPPVCGLAAGADVD..EIRMRERESGRRGAIPET..NLFkasREAVPQ.....NDYDREAMYRSGQAI...S..V..NR..GRVLTADDFaydEGQDP....SFTPGANHLRAAELKRAAEQTAFGEELRNSCHQARLRTALTRPELPAGIYYLYDFVQTYVDHPD..gRVKLNPQLVLVAQHAG-NTMLAQRLW.SIAEDK......NAWLRDLIEMAYMIV.NDPYLRTEQQLSAIC.........
A0A5F2P0F9_9ADEN/60-262             .................sm--APTCGIASGADMD..EFRMYDRDVNRKATVPEC..NLFkapRTEVPQ.....NDYERDAMYYAGQGI...K..V..DK..NRVLEPEDF...RGD-P....TFNRAVNHLKAAELKRHSDQTAFNEEYRNMSHQAKIRTALTRREVKSGIYYLYDFVQTYMDHPD..gRVALNPQLVLVAQHAG-NSILAHRLW.AIAEDK......NAWLRELIEMTYMIV.NDPYMSTNQQLSAIC.........
A0A096ZH18_9ADEN/85-291             ..................l-GPPVCGLAAGADVD..EIRMRERESGRRGAIPET..NLFkasREAVPQ.....NDYDREAMYRSGQAI...S..V..NR..GRVLTADDFaydEGQDP....SFTPGANHLRAAELKRAAEQTAFGEELRNSCHQARLRTALTRPELPAGIYYLYDFVQTYVDHPD..gRVKLNPQLVLVAQHAG-NTMLAQRLW.SIAEDK......NAWLRDLIEMAYMIV.NDPYLSTEQQLSAIC.........
A0A1D8QMB5_9ADEN/70-276             ..................a-GPPVCGLASGAGLD..AVRMAERDAHRRGAVQET..NLFkdtRDRVPQ.....NDYEREMMYRSGQMI...E..V..DG..QRVLRPEDFvpmSEEDP....TFSPAANHIRAAELKRAARQTQFGEEMRNCRHQTRIRTALLRPELGAGIYYLYDFVQTYLEHPD..gRVKLNPQLVLVAQHAG-NTLLAQRLW.AIAEDR......NAWLRDLIEMAYVIV.NDPYLTTEQQVAAVC.........
U5NEE5_9ADEN/62-265                 ................ega---IACGIAAGSGLD..EVRMRERDAARRAAVPET..NLFkarRDVVPN.....NDYERDVMYRAGQAI...S..V..DR..NRVLTPEDF...EGPDS....TFTSAVNHLKAAELKRASEQTAFGEELRNNCHQTRIRTALLRPEVASGIYYLYDFVQTYLEHPD..gRVKLNPQLVLVAQHAG-NSMLAQRLW.AIAEEK......NAWLRDMIEMAYMIV.NDPYLSVEQQLAAVC.........
#=GC seq_cons                       .................th.....su.ustt.....c.RhphcccspcuhVPpp..NLF...RDt.sp.....s-t.R-hha+uGptl...p..l..sp..pRVLps-DF...tspts....uhSPApsHlpAAcLhpAhEQTsptEpshpcsFps+lRTLlsR.ElslGLhaLaDFlpsalppPs...spsLssQLhLlsQHup.NshhRctLh.sIuEsc......scWLhDLIshltsIV.p-ppLolscplAAIs.........
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