#=GF ID ArenaCapSnatch
#=GF AC PF17296.6
#=GF DE Arenavirus cap snatching domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE PDB:4i1t
#=GF GA 27.00 27.00;
#=GF TC 33.20 31.50;
#=GF NC 25.30 22.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF CL CL0236
#=GF RN [1]
#=GF RM 20862324
#=GF RT The N-terminal domain of the arenavirus L protein is an RNA
#=GF RT endonuclease essential in mRNA transcription.
#=GF RA Morin B, Coutard B, Lelke M, Ferron F, Kerber R, Jamal S,
#=GF RA Frangeul A, Baronti C, Charrel R, de Lamballerie X, Vonrhein C,
#=GF RA Lescar J, Bricogne G, Gunther S, Canard B;
#=GF RL PLoS Pathog. 2010;6:e1001038.
#=GF DR INTERPRO; IPR026382;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain represents the N-terminal domain of the Arenavirus
#=GF CC polymerase that is involved in cap snatching during
#=GF CC transcription initiation.
#=GF SQ 18
#=GS L_GOGV/8-177 AC J7H8Q3.1
#=GS A0A2U7PZY1_9VIRU/1-86 AC A0A2U7PZY1.1
#=GS L_TACVF/1-172 AC P20430.1
#=GS Q6XQI8_BCNVU/1-171 AC Q6XQI8.2
#=GS A0A0H3Y8T2_9VIRU/7-177 AC A0A0H3Y8T2.1
#=GS L_LATVB/1-172 AC B2MW49.1
#=GS L_LASSJ/1-172 AC O09705.1
#=GS L_IPPYV/1-172 AC Q27YE1.1
#=GS L_LYCVA/1-172 AC P14240.1
#=GS Q915A5_PIARV/1-171 AC Q915A5.1
#=GS J7HBG8_9VIRU/1-171 AC J7HBG8.1
#=GS A0A2Z5DEQ8_9VIRU/1-172 AC A0A2Z5DEQ8.1
#=GS A0A1P8PFC9_9VIRU/7-177 AC A0A1P8PFC9.1
#=GS A0A0F7LCD5_9VIRU/7-176 AC A0A0F7LCD5.1
#=GS L_GTOVV/1-172 AC Q6UY70.1
#=GS C5ILC4_9VIRU/1-172 AC C5ILC4.1
#=GS L_PIRVV/1-171 AC Q6RSS2.1
#=GS L_TAMVU/2-174 AC A9JR23.1
L_GOGV/8-177 .........................dselerl--------KGLVLEVLSYERDLYR--PGWISNTA-GEMAMNAIKLRSTIHELNCCRDTGLKHNNDLKEMNELFDEAIGSHETVKTIVPDGYLIdkNN..NVLT..VLEVSTRTEPSDQTKKVQLDRLKYDGFENLLRPLG..WTLNVITISEKKPRIGRIPEILMFKLLSTSLSILSYT-t...
A0A2U7PZY1_9VIRU/1-86 ................................--------------------------------------------------------------------------------------MPDGYNL..MG..KTLI..LLETFVRVNPDDFERKWKADMSKLISLKEDLCKIG..ITLVPVVDGRSSYNTQYLPEWATERFRWLLIEILR---gvk.
L_TACVF/1-172 ................................MDETVSELKDLVRKHIPNRHEFAHQKDAFLSHCHSGSLLQEGFKLLSNLVELESCESHACHLNTCQKYVDVILSDHGIPCPTLPKVIPDGFKL..TG..KTLI..LLETFVRVNPEEFERKWKSDMTKLLNLKQDLLRSG..ITLVPVVDGRTNYSNRFTPEWVVERIRWLLIEILRKSR....
Q6XQI8_BCNVU/1-171 ................................MSEYLDELKELIRKWIPDEEMYIEQKTSFLSQVNLRSAVIEGLKLLSIIIEIDSCKKHGCVHNK-NKTVNQILRDHKIVGPTLPDIVPDGYRV..IG..STII..LLEAFVRVSHESFEIKYKSDFEKLMQLSKDLSRCG..LTLIPVVDGRSNYYTEHFPDWTIERMRWLILKIT----nflr
A0A0H3Y8T2_9VIRU/7-177 ...........................edael-----KKLKEIVLQVLSYERDLY--KPGWISDIAGEM-AVNAIKLRSTIHELNCCRDTGLKFNNELTEMNSILDEAIGSHETVKTIVPDGYLI..DG..NNNIisILEASTRAEPADQNRKVELDRAKYDGVEDILRPIG..WSLNIITISETKPRINNIPESLMFKLLSTSISILSYT-t...
L_LATVB/1-172 ................................MDDIVNQLFDLLRKHFPARPKVTEQITLVTCQNDAKMILTEGFKLLSLLVELDSAEANNCTHNSDSLTIEGILRKEGIMSIALPRIVPDGFSL..YG..NVLI..LLETFVRVNPVSFEQKYNQDMSKLLSLKDDLSLCG..ITLVPLVDGRTNYYNRFVDDWVIERFRWLLLQLIKF--vr..
L_LASSJ/1-172 ................................MEEDIACVKDLVSKYLVDNERLSRQKLAFLVQTEPRMLLMEGLKLLSLCIEVDSCNANGCEHNSEDKSVERILHDHGILTPSLCLWYPDGYKL..TG..NVLI..LLECFVRSSPANFEQKYIEDFKKLEQLKEDLKSVD..INLIPLIDGRTSFYNEQIPDWVNDKLRDTLFSLLKYAQ....
L_IPPYV/1-172 ................................MEESLRETKLLISRYLRQDERIARQKLAFLGQSEPRSLLIEGLKLLSLCIEIDSCDTNCCTHNTEGQSVENFLFQNHILCPSLPLVVPDGMKL..NG..NILI..ILECFVRSNPTNFQQKYQEDSVKLDSLKGDLERAG..ISLIPIIDGRTSYYNSLMEEWVCDQFRHNLFKLLEF--eq..
L_LYCVA/1-172 ................................MDEIISELRELCLNYIEQDERLSRQKLNFLGQREPRMVLIEGLKLLSRCIEIDSADKSGCTHNHDDKSVETILVESGIVCPGLPLIIPDGYKL..ID..NSLI..LLECFVRSSPASFEKKFIEDTNKLACIREDLAVAG..VTLVPIVDGRCDYDNSFMPEWANFKFRDLLFKLLEYSN....
Q915A5_PIARV/1-171 ................................MEEYVSEFKDMVRKWVPEWEELSEQKNNVLAQVKDRAITIEGLKLLSMLVEVDSCKKHSCRHNTR-MTVNAILRELKVTCPTLPDVTPDGYCM..VG..DVLI..LLEVFVRTSQEAFEKKYNQDFLKLMQLSSDLKRQN..ITLVPVIDGRSSYYVEYIPDWVVERLRWLLLKLM----dglr
J7HBG8_9VIRU/1-171 ........................mdpdtnll--------KNVILEILSIEPDLYKQSSI---VDDPYKLAMSAIRLRATIHELNCCRDLGIIHNTKEISLNMVIDRAIPIHPTFQHIVPDGYTIdrAN..MTII..VLEASTRSMPSDQKRKITSDKLKYSGVEDHLKHEG..WLFNIIVISETKPRNGNVPERLLFELLKLSLSILSYS-d...
A0A2Z5DEQ8_9VIRU/1-172 ................................MDETIINLKDLVRKYIPDLPEITLQKELLLSQQQVDMILTEGFKLLALIVELESAYSNNCTPNHEGMTVEQILRDNKVLTPSLPKLIPDGYNL..LG..ETLI..LLETFVRVDSVSFEQKWKSDMAKLLCLKDDLARAG..ITLVPIVDGRTNYYNRFVPDWVTERFRWLMLNLVKGS-r...
A0A1P8PFC9_9VIRU/7-177 ..............................ed--AELARLKEIVLQVLSYERDLY--KPSYMTNIAGEM-AIGAIRLRSSIHELNCCRDTGLKYNGELKEMNELLDESIGPHETIKTIVPDGYLI..DKnnNILS..ILEASTRSEPSDQSRKVELDRLKYDGLDSLLRPNG..WTLNLILISERKPRIGKVPEALMFKLLSTSLSILSYT-t...
A0A0F7LCD5_9VIRU/7-176 dvelerlqklvleilsyerdlykpgwisniag------------------------------------EMATNAIRLRSTVHELNCCRDIGLRFNGELREINTLLDEAIGTHETVKLVIPDGFLIdkTN..NVMT..VLETSTRAEPTDQNRKVSLDRQKYDGVEDILRPNGwsLNLITICERKPR--LGKIPEILMFKLLSTSLSILSYT-t...
L_GTOVV/1-172 ................................MDEKVFVLKDFIRRQVPDIPELSYQKEALLSQVEVPMVLTEGFKLLSCLVEIESCRKNSCECNFEQKFVDTILSENGVVAPTLPKVIPDGYRF..FN..KTLI..LLETFVRVNPEEFEKKWKTDMAKLLSLKEDIHRTG..ITLVPVVDGRGNYNTDLLPDWATERFRWLLIDLLRESR....
C5ILC4_9VIRU/1-172 ................................MDSLKNELLQLISRNFPNDERLAPQKLKVLCQTEPKFIMIEGLKLLSTCIEIDICDENGCIHNTEEKSVELILRENGFVVPSLPCVTPDGFKV..SG..NMLI..LLECFVRLNPLEYEQKYNNDMKKLSSLRGDLEHSG..ITLVPLVVGRSGYENNSIPDWVVFKFKNLIFRLLEYV-q...
L_PIRVV/1-171 ................................MEEHVNELHDLVRKWVSDDENFAEQKAIFLSQTKLRAITIEGLKLLSTIVEVDSCQKNSCIHNR-EKTLNSILRDNKIVCPTLPEIVPDGYRL..IG..DVLI..LLEVFVRSNQESFEKKYEQDYTKLMQVKKDLQSHG..ITLVPMIDGRSSYYVEFMPDWVVEKIRWHLIKLMD---llk.
L_TAMVU/2-174 .........................secltyf-----NELKDLVRKWVPDEDTYVEQKTVLLSQVNFSSIVTEGLKLLSTLIEVDSCVKHGCIHNR-SKTVNQILYDHRIVGPTLPDVVPDGYRV..SG..STLI..LLETFVRVNQESFECKYRHDFEKLMQLSKDLAKCG..LTLVPVIDGRSSYYIERLPDWVIERMRWLLLRIMS---nlr.
#=GC seq_cons ................................Mpp.ltpLK-Llp+hlspccclscQK.shLuQspschlhhEGlKLLSpllEl-SCccsuCpHNs-t+olspILc-stlssPTLPpllPDGYpl..sG..ssLI..LLEsFVRssPssFE+KappDhtKL.sLccDLppsG..lTLlPllDGRosYhsphlP-Wlh-+hRhLllplLphs.p...
//
