#=GF ID   Arena_nucleocap
#=GF AC   PF00843.21
#=GF DE   Arenavirus nucleocapsid N-terminal domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_1333 (release 2.1)
#=GF GA   27.20 27.20;
#=GF TC   28.20 145.30;
#=GF NC   24.80 19.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   8599223
#=GF RT   Oliveros virus: a novel arenavirus from Argentina. 
#=GF RA   Bowen MD, Peters CJ, Mills JN, Nichol ST; 
#=GF RL   Virology 1996;217:362-366.
#=GF RN   [2]
#=GF RM   21085117
#=GF RT   Cap binding and immune evasion revealed by Lassa nucleoprotein
#=GF RT   structure.
#=GF RA   Qi X, Lan S, Wang W, Schelde LM, Dong H, Wallat GD, Ly H, Liang
#=GF RA   Y, Dong C;
#=GF RL   Nature. 2010;468:779-783.
#=GF DR   INTERPRO; IPR035083;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This N-terminal domain folds into a novel structure with a deep
#=GF CC   cavity for binding the m7GpppN cap structure that is required
#=GF CC   for viral RNA transcription [2].
#=GF SQ   18
#=GS NCAP_GTOVV/4-334        AC Q8AZ66.1
#=GS Q8BDE3_TAMVU/3-338      AC Q8BDE3.1
#=GS J7HCF9_9VIRU/2-330      AC J7HCF9.1
#=GS NCAP_TACVF/4-334        AC P18140.1
#=GS A0A0F7LDH0_9VIRU/7-338  AC A0A0F7LDH0.1
#=GS A0A0H3YA18_9VIRU/7-338  AC A0A0H3YA18.1
#=GS NCAP_LATVB/4-333        AC Q8BDE6.1
#=GS NCAP_IPPYV/4-339        AC Q27YE3.1
#=GS Q8BD27_BCNVU/3-336      AC Q8BD27.1
#=GS A0A2Z5DEG4_9VIRU/4-333  AC A0A2Z5DEG4.1
#=GS NCAP_PIARV/2-335        AC P03541.1
#=GS A0A1P8PFC6_9VIRU/7-338  AC A0A1P8PFC6.1
#=GS NCAP_LASSJ/4-339        AC P13699.1
#=GS NCAP_LYCVA/4-335        AC P09992.1
#=GS NCAP_GOGV/7-338         AC J7H5M4.1
#=GS A0A2U7PK98_9VIRU/4-335  AC A0A2U7PK98.1
#=GS NCAP_PIRVV/3-334        AC Q8BDE4.1
#=GS C5ILC2_9VIRU/4-334      AC C5ILC2.1
NCAP_GTOVV/4-334                   ........SKEIPSFRWTQSLRRELGMFTEPTKSSVLNDAKLIADSLDFTQVSQVQRLLRKSKRGDTDLDKLRDLNKEVDRLMSMKSVQNNTVLKVGDLGKDELMDLASDLEKLKKKI..GDR...E..-.SNSP.RMYM.GNLTQSQLEKRAGILRTLGFQ-QQRGA-A..GGVVRLWDVSDPS.KLNNQFGSMPALTIACMTVQGGETMNNVVQA.LTSLGLLYTVKYPNLDDLEKLTLEHDCLQIITKDESALNISGYNFSLSAAVKAGASLIDGGNMLETIKVTPNNFSSIVKAALNVKRREGMFIDERPGNRNPYENLLYKLCLSGEGWPYIGSRSQILGRSWDNTSVDL-n.
Q8BDE3_TAMVU/3-338                 ......dq--SVPSFRWVQSLRRGLSAWTTPVKADVLNDTRALLSGLDFSKVASVQRMMRREKRDDNDLTNLRDLNKEVDSLMTMRSSQKNMFLKVGSLSKDELMELSSDLNKLKEKV..QRS...E..RiSGSS.GVYQ.GNLTTTQLTRRSEILQLVGIQRPGL-NRR..GGVVKIWDIKEPEhSLINQFGSTPAVTISCMAEQGGETLNDVVARpNRSVGYFTQQSFLIWVTWRALSSKHSCLKVITQEESQINISGFNLSLSAAVKAGACLVDGGNMLETIKVEESTFTTIIKTLLEIKSKERMFVDITPGQRNPYENLLYKLCLSGEGWPYIASRSQIKGRAWDNTVIEF-d.
J7HCF9_9VIRU/2-330                 ..nqlvvk----------KHLNKVLRPFQANLNNDLFKDVKLISAKININEVNDVLRRLRKETKTRDDLQKLRKLNKYLAEGTNVTSEQVVVEIDSTQMSDEDLMQCIDNLERIKKKA..EYKggrD..K.PSSK.FEFE.TGLSHEDHERFSSLFASFVPQKPNPRN-E..NNKPKSWIGVSSE.ELANQFGTSPSITVSIMLQRSGCTFKELFEA.LNDISLLDAGMFVNASVIKALSSKHHCLDVVEFS-VPKNSSGYNITVKSVVKAANSIS-SHPKLEKIMVTDQNRTKLLSVLVAAQKDLQLEIKL-DEERTLFEDLFYKVCVSPNGACVVSIRSNLTGRGWDNTVFKL-r.
NCAP_TACVF/4-334                   ........SKEVPSFRWTQSLRKGLSQFTQTVKSDILKDAKLIADSIDFNQVAQVQRVLRKTKRTDDDLNKLRDLNIEVDRLMSMKSVQKNTIFKVGDLARDELMELASDLEKLKDKI..KRT...E..-.SNGT.NAYM.GNLPQSQLNRRSEILRTLGFA--QQGGRP..NGIVRVWDVKDSS.KLNNQFGSMPALTIACMTVQGGETMNNVVQA.LTSLGLLYTVKYPNLSDLDKLIPNHECLQIITKEESSINISGYNLSLLAAVKAGASILDGGNMLETIRVSPDNFSSLIKNTLQVKRREGMFIDDRPGSRNPYENLLYKLCLSGDGWPYIGSRSQIMGRSWDNTSVDLT..
A0A0F7LDH0_9VIRU/7-338             ..aavnql-------ALKKKLNKMLSPFQRELNNQIFKDVKALRGGLDINKINDVLRRLRKETKGPNDLERLRSLNETTAGLSGMVAVQRVIEIDSTLMSDEELIQCIENIDMIKKKAeyKGG...S..K.PRTS.EFESeTGMTKSDHEVFNKLFNRFVPRK-ESGPAG..PSTPKSWIGINPA.DLANQFGTSPAITICLIMMRTNSPFKQIIDA.LYDISILDSGMFVNASVIKAMTPQHPCLECVEYT-VPKNSSGYNITVKAIVKA-ANVLSKLPKLEKLVLDDDNRVEIIRTLLSIQRELGIKIQI-NEERGLFEDVFYKICVSPNGPCVVSIRSELTGRGWENTVFRL-r.
A0A0H3YA18_9VIRU/7-338             aavnqlal---------KKKLNXMLSPFQRELNNQIFKDVKALRGGLDINKINDVLRRLRKETKGPNDLERLRSLNETTAGLSGMVAVQKVIEIDSTLMSDEELIQCIENIDMIKKKAeyKGG...S..K.PRTS.EFESeTGMTKSDHEMFNKLFNRFVPRK-ESGPAG..PSTPKSWTGINPA.DLANQFGTSPAITICLIMMRTNSPFKQIIDA.LYDISILDSGMFVNASVIKAMTPQHPCLECVEYT-VPKNSSGYNITVKAIVKA-ANVLSKLPKLEKLVLDDDNRVEIIRTLLFIQRELGIKIQM-NEERGLFEDVFYKICVSPNGPCVVSIRSELTGRGWENTVFRL-r.
NCAP_LATVB/4-333                   .......a-SEVPSFRWTQSLRRGLSHFTTSAKGDVLRDAKSLVDGLDFNQVSQVQRVMRKDKRSDDDLSKLRDLNRSVDSLMVMKNKQNNVSLKIGSLSKDELMDLATDLEKLKRKI..NLG...D..-.RQGP.GVYQ.GNLTSAQLEKRSEILKSLGFQ---PRANQ..NGVVKVWDIKNPK.LLINQFGSIPALTIACMSVQGAEQMNDVVQG.LTSLGLLYTVKYPNLDDLDKLSKDHPCLEFITKEESANNISGYNLSLSAAVKAGACLVDGGNMLETILVKPDNFQDIVKSLLVVKRQEKMFVNEKPGLRNPYENILYKLCLSGEGWPYIGSRSQIVGRAWENTTVDL-s.
NCAP_IPPYV/4-339                   ........SKEVKSFLWTQALRRELGQYCSTVKSSIIKDAQSLLHSLDFSEVSNIQRLMRKDKRNDSDLKRLRDLNQAVFNLVELKSTQQKNVLRVGKLTSDDLLVLAADLDRLKNKV..MRT...E..R.PQTL.GVYM.GNLTNQQLDQRKRLLDMIGISNARNAPRPgaDGVVRVWDVKDSS.LLNNQFGTMPSLTLACMSKQGQYELNDVVQS.LTDLGLVYAAKYPNAMDLEKLTQAHPVLSIIDVSKSSINVSGYNFSLSAAVKAGACMLDGGNMLETLKVTPQNLEDILASMLKVKRAHSMFVSDTPGDRNPYENLLYKVCLSGNGWPYIACRTSLTGRAWDNTVVDL-g.
Q8BD27_BCNVU/3-336                 .....dqv---VHSFRWTQSLRRGLSNWTCPVKADVLNDTRALLSGLDFAKVASVQRMMRRDKRDESDLTSLRDLNKEVDSLMTMKSTQKNMFLKIGSLSKGELMELSGDLNKLKDKV..QRT...E..R.PPGSgGQYQ.GNLTTTQLTRRGELLQFIGIQKAGRVG-T..NGVVKVWDVKDSS.LMINQFGSMPALTISCMAEQGGETLNDVVQG.LTDLGLLYTAKYPNLNDLEALSEKHPCLKVITQEESQINISGYNLSLSAAVKAGACLIDGGNMLETIKIDTSTFTTVIKTLLEVKARERMFVSSVPGQRNPYENILYKLCLSGEGWPYIASRSQIKGRAWDNTVVEF-d.
A0A2Z5DEG4_9VIRU/4-333             ........SKEVPSFRWTQALRRGLSEFTTATKIDVMKDAKSLIDHLDFSQVAQVQRVMRKTKRSESDLEKLINLNRDVHNLMSMKTTQSNVVLSLSDLQKDELMDLSADLDKLKKKV..TTT...E..R.-GSP.GIYQ.GNLTQQQLEKRTDLLRSLGFS--KQG-RS..DTVVRVWDINDSN.KLVNQFGSIPALTIACMTVQGDTSMNDVIQG.LSSLGLLYTVKYPNLKDLEKLTNEHDCLEIITKEESSNNISGFNFSLSAAVKAGASIIDGGNMLETIRVSPDIMTQIIKSLLIVKRKEGMFVDPRPGQRNPYENILYKLCLSGEGWPYISSRTQIKGRAWDNTTVDI-q.
NCAP_PIARV/2-335                   ........SDNIPSFRWVQSLRRGLSNWTHPVKADVLSDTRALLSALDFHKVAQVQRMVRKDKRTDSDLTKLRDMNKEVDALMNMRSVQRDNVLKVGGLAKEELMELASDLDKLRKKV..TRT...E..G.LSQP.GVYE.GNLTNTQLEQRAEILRSMGFANARPAGNR..DGVVKVWDIKDNT.LLINQFGSMPALTIACMTEQGGEQLNDVVQA.LSALGLLYTVKFPNMTDLEKLTQQHSALKIISHEPSALNISGYNLSLSAAVKAAACMIDGGNMLETIQVKPSMFSTLIKSLLQIKNREGMFVSTTPGQRNPYENLLYKICLSGDGWPYIGSRSQVQGRAWDNTTVDL-d.
A0A1P8PFC6_9VIRU/7-338             .aavnqla--------LKKRLNKLLAPFQSELNNQILKDVKALRAGLDANKINDVLRRLRKDTKGPNDLARLRELNETAAGLSAMVAVQRTVEIDSSLMSDEELIQCIENIEAIKKKA..EYK...GgsK.PRTS.EFESeTGMSRSDHETFNRLFSRFVPR-KDSGPTG..PTTPKSWVGIDAR.DLANQFGTSPAITISLMMMRTNSPFKQIIEA.LYDISLLDSGMFVNSSVVKAMTAQHPCLECVEYS-VPKNSSGYNITVKAVVKA-ANVLSKLPKVEKLVIDDDNRVEIIRTLLSIQKELGIKIQ-ISEERGIFEDVFYKICVSPNGPCVVSIRSELTGRGWDNTVFRL-k.
NCAP_LASSJ/4-339                   ........SKEIKSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKERRDDNDLKRLRDLNQAVNNLVELKSTQQKSILRVGTLTSDDLLILAADLEKLKSKV..IRT...E..R.PLSA.GVYM.GNLSSQQLDQRRALLNMIGMSGGNQGARAgrDGVVRVWDVKNAE.LLNNQFGTMPSLTLACLTKQGQVDLNDAVQA.LTDLGLIYTAKYPNTSDLDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQTMDGILKSILKVKKALGMFISDTPGERNPYENILYKICLSGDGWPYIASRTSITGRAWENTVVDLE..
NCAP_LYCVA/4-335                   ........SKEVKSFQWTQALRRELQSFTSDVKAAVIKDATNLLNGLDFSEVSNVQRIMRKEKRDDKDLQRLRSLNQTVHSLVDLKSTSKKNVLKVGRLSAEELMSLAADLEKLKAKI..MRS...E..R.PQAS.GVYM.GNLTTQQLDQRSQILQIVGMRKPQQGA--..SGVVRVWDVKDSS.LLNNQFGTMPSLTMACMAKQSQTPLNDVVQA.LTDLGLLYTVKYPNLNDLERLKDKHPVLGVITEQQSSINISGYNFSLGAAVKAGAALLDGGNMLESILIKPSNSEDLLKAVLGAKRKLNMFVSDQVGDRNPYENILYKVCLSGEGWPYIACRTSIVGRAWENTTIDLT..
NCAP_GOGV/7-338                    .aavnqla--------LKKKLNKMLAPYQRELNNQIFKDVKALRVGLDINKVNDTLRRLRKETKGPNDLKNLRDLNETAAGLSGMVATQRTVEIDSSLMSDEELIQCIENIDVIKKKAeyKGG...S..R.PRIS.EFESeTGMSKSDHEMFNKLFNRFAPK-KDPGPAA..FSTPKSWVGISPA.DLANQFGTSPAITICLIMMRTNSPFKQILDA.LHDISLLDQGMFVNASVVKAMTSQHPCLDCVEYT-VPKNSSGYNITVKAVVKA-ANVLSKLPKVEKLVIDDDNRVEIIRTLLTIQRELNIKIQV-NEERGLFEDIFYKICVSPNGPCVVSIRSELTGRGWENTIFR--lr
A0A2U7PK98_9VIRU/4-335             ........SKEVPNFRWLQSLRRGLSDFTTPVKSDVLKDAKLIADGLDFSQVALVQRVLRKTKRTDADLDKLRDLNREVDNLMMMRSSQKNTVLKMGDLSKSDLMDLAADLEKLKKKV..GQT...E..R.SSTG.GVYL.GNLTQSQLSKRTDLLRRLGFQ--QQQMRS..SGVVRVWDVADST.RLNNQFGSIPALTIACMTVQGGDTMGNVVQA.LTSLGLLYTVKFPNLTDLEKLTAEHDCLQIITRDESAINISGYNFSLSAAVKAGASLLDGGNMLETIKVTPSNFSSIIKAVLVVKRKEGMFVDEKPGNRNPYENLLYKLCLSGEGWPYIGSRSQVKGRSWENTIVDL-s.
NCAP_PIRVV/3-334                   ........SDNVASFRWTQALRRGLSNWTNPVKSDVITDTRALLAALDFDRVAQVQRLMRKDKRTDTDLTKLRDLNKEVDALMNMRTTQKDNVLRVGGLSKDELMELASDLQKLKKKV..LRV...E..G.SGQP.GVYA.GNLTTTQLEQRSKILRDMGFA--QLRGNP..SGVVKVWDIKDSS.LLINQFGSMPAVTMACMTEQGGESLNDVVQG.LSALGLLYTVKYPNMSDLEKLADQYPCLGYITQEQSQINVSGYNLSLSAAVKAGACMLDGGNMLETIQVKPTMFSSMIKAVLEVKSKERMFVSEAPGQRNPYENLLYKLCLSGDGWPYIGSRSQVKGRAWDNTTVDLT..
C5ILC2_9VIRU/4-334                 ........SKEVKSFLWLQTLRRELSPFCTDVRAKVVKDAVSLINGLDFSMVSDVQRLMRKDKRNDEDLMKLRELNQTVDGLVDLKSSNKKNRVGVGKLTSDELMILATDLEKLKKKV..TRT...E..-.ARGP.GVYR.GNLSQDQLGRRSELLNMIGMGTPRPTR--..NTVVRVWDVKDSS.LLNNQFGTMPSLTLACLTRQTRVDLNDSVQA.CVDLGLIYTAKFPNMDDLDKLKNKHPVLDYVSNCDSAINISGYNLSLASLVKAGASLMKGGDMLETIELNSRNIDDVIKATLTARNKVQMFVSEVPGERNPYENLLYKICLSGEGWPYISSRTSIKGRSWDNTVIDMT..
#=GC seq_cons                      .........ppl.SFtWsQuLRRtLSsFssslKusVlKDs+uLhsGLDFscVusVQRhhRK-KRsDsDLp+LRDLNcpVcuLhsM+SsQ+sshL+lGpLSc-ELMpLuuDL-KLKKKl..pps...E..+.spss.GhYp.GNLTpoQL-pRscLLpplGhp..ppusts..sGVV+VWDlpDus.hLsNQFGohPALTIACMshQGspshN-VVQA.LosLGLLYTsKaPNhsDL-+LospHPCLchIopppSslNISGYNlSLuAAVKAGAsllDGGNMLETIpVsssNhssIIKolLplK+c.sMFlsptPGpRNPYENlLYKlCLSG-GWPYIuSRSplpGRuWDNTllDL.p.
//