#=GF ID AsiA
#=GF AC PF09010.14
#=GF DE Anti-Sigma Factor A
#=GF AU Mistry J;0000-0003-2479-5322
#=GF AU Sammut SJ;0000-0003-4472-904X
#=GF SE pdb_1jr5
#=GF GA 25.00 25.00;
#=GF TC 26.50 54.20;
#=GF NC 24.90 23.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 11830637
#=GF RT Solution structure and stability of the anti-sigma factor AsiA:
#=GF RT implications for novel functions.
#=GF RA Urbauer JL, Simeonov MF, Urbauer RJ, Adelman K, Gilmore JM,
#=GF RA Brody EN;
#=GF RL Proc Natl Acad Sci U S A. 2002;99:1831-1835.
#=GF DR INTERPRO; IPR015100;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Anti-sigma factor A is a transcriptional inhibitor that inhibits
#=GF CC sigma 70-directed transcription by weakening its interaction
#=GF CC with the core of the host's RNA polymerase. It is an all-helical
#=GF CC protein, composed of six helical segments and intervening loops
#=GF CC and turns, as well as a helix-turn-helix DNA binding motif,
#=GF CC although neither free anti-sigma factor nor anti-sigma factor
#=GF CC bound to sigma-70 has been shown to interact directly with DNA.
#=GF CC In solution, the protein forms a symmetric dimer of small (10.59
#=GF CC kDa) protomers, which are composed of helix and coil regions and
#=GF CC are devoid of beta-strand/sheet secondary structural elements
#=GF CC [1].
#=GF SQ 97
#=GS A0A7S5SK01_9CAUD/2-82 AC A0A7S5SK01.1
#=GS A0A240F2V9_9CAUD/2-83 AC A0A240F2V9.1
#=GS K0G7R3_9CAUD/2-81 AC K0G7R3.1
#=GS E5E4L6_9CAUD/2-80 AC E5E4L6.1
#=GS I7AUC1_9CAUD/2-81 AC I7AUC1.1
#=GS Q56ED8_9CAUD/2-83 AC Q56ED8.1
#=GS A0A6G6XH77_9CAUD/2-81 AC A0A6G6XH77.1
#=GS A0A7G9VYE8_9CAUD/2-82 AC A0A7G9VYE8.1
#=GS A0A7S9XC63_9CAUD/1-84 AC A0A7S9XC63.1
#=GS A0A1Z1LYR6_9CAUD/1-81 AC A0A1Z1LYR6.1
#=GS A0A223LF16_9CAUD/3-83 AC A0A223LF16.1
#=GS E5DHZ2_9CAUD/1-81 AC E5DHZ2.1
#=GS A0A2U7NLX5_9CAUD/20-101 AC A0A2U7NLX5.1
#=GS A0A3P4AA03_9CAUD/2-81 AC A0A3P4AA03.1
#=GS A0A0B6VPM1_9CAUD/1-80 AC A0A0B6VPM1.1
#=GS Q6WHK8_BPKVM/10-94 AC Q6WHK8.1
#=GS A0A0G2SSC2_9CAUD/1-82 AC A0A0G2SSC2.1
#=GS A0A7T5UD27_9CAUD/1-81 AC A0A7T5UD27.1
#=GS A0A6B9J5B4_9CAUD/2-82 AC A0A6B9J5B4.1
#=GS A0A023W6W7_9CAUD/1-95 AC A0A023W6W7.1
#=GS A0A0A7HC73_9CAUD/1-81 AC A0A0A7HC73.1
#=GS A0A1D3RL15_9CAUD/1-81 AC A0A1D3RL15.1
#=GS A0A240F458_9CAUD/2-83 AC A0A240F458.1
#=GS A0A097J6U1_BPR32/2-81 AC A0A097J6U1.1
#=GS J7I4K9_9CAUD/1-83 AC J7I4K9.1
#=GS A0A5B9NCJ7_9CAUD/1-81 AC A0A5B9NCJ7.1
#=GS D9I6I4_9CAUD/1-80 AC D9I6I4.1
#=GS R9TEX8_9CAUD/10-94 AC R9TEX8.1
#=GS A0A0K1LP27_9CAUD/1-81 AC A0A0K1LP27.1
#=GS A0A060AMS7_9CAUD/4-84 AC A0A060AMS7.1
#=GS A0A6B9Y0V3_9CAUD/1-81 AC A0A6B9Y0V3.1
#=GS A0A0U4IH54_9CAUD/8-90 AC A0A0U4IH54.1
#=GS A0A7G5AYG1_9CAUD/3-83 AC A0A7G5AYG1.1
#=GS A0A088FW16_9CAUD/2-81 AC A0A088FW16.1
#=GS A0A6J3ZYV6_BPT2/2-81 AC A0A6J3ZYV6.1
#=GS A0A219YC78_9CAUD/2-82 AC A0A219YC78.1
#=GS A0A5P8PHQ3_9CAUD/1-95 AC A0A5P8PHQ3.1
#=GS A0A873WSL1_9CAUD/1-78 AC A0A873WSL1.1
#=GS A0A868BRA5_BPFBB/1-82 AC A0A868BRA5.1
#=GS A0A411BIC7_9CAUD/3-84 AC A0A411BIC7.1
#=GS A0A3Q9R7G8_9CAUD/2-82 AC A0A3Q9R7G8.1
#=GS A0A410T4S4_9CAUD/1-81 AC A0A410T4S4.1
#=GS Q7Y4Q5_BPR69/2-81 AC Q7Y4Q5.1
#=GS A0A0B5A2R8_9CAUD/1-81 AC A0A0B5A2R8.1
#=GS M1EAI1_BPS16/1-81 AC M1EAI1.1
#=GS E5EQ30_9CAUD/1-80 AC E5EQ30.1
#=GS A0A2S1GM14_9CAUD/1-82 AC A0A2S1GM14.1
#=GS A0A6B9STF7_9CAUD/10-94 AC A0A6B9STF7.1
#=GS A0A346FJY1_BPT6/2-81 AC A0A346FJY1.1
#=GS A0A192YBU6_9CAUD/1-77 AC A0A192YBU6.1
#=GS A0A411BAG5_9CAUD/2-82 AC A0A411BAG5.1
#=GS A0A2Z4QAR6_9CAUD/1-81 AC A0A2Z4QAR6.1
#=GS E5EZ20_BPAC4/2-80 AC E5EZ20.1
#=GS ASIA_BPT4/2-81 AC P32267.1
#=GS A0A0B6VLD1_9CAUD/1-80 AC A0A0B6VLD1.1
#=GS D4ZA57_BPAR1/2-81 AC D4ZA57.1
#=GS A0A067ZK43_9CAUD/2-81 AC A0A067ZK43.1
#=GS A0A7T8F0N6_9CAUD/2-82 AC A0A7T8F0N6.1
#=GS A0A3T0IMA2_9CAUD/1-81 AC A0A3T0IMA2.1
#=GS A0A7T6ZLP2_9CAUD/1-78 AC A0A7T6ZLP2.1
#=GS I7J414_BPPR1/1-81 AC I7J414.1
#=GS E5FJ32_9CAUD/1-81 AC E5FJ32.1
#=GS E5DQQ2_9CAUD/2-82 AC E5DQQ2.1
#=GS A0A1W6JU55_9CAUD/2-81 AC A0A1W6JU55.1
#=GS A0A6H0X733_9CAUD/10-94 AC A0A6H0X733.1
#=GS A0A0A7HD11_9CAUD/1-81 AC A0A0A7HD11.1
#=GS A0A2H4YGT9_9CAUD/1-81 AC A0A2H4YGT9.1
#=GS A0A345AV77_9CAUD/2-82 AC A0A345AV77.1
#=GS A0A7T5QYJ2_9CAUD/3-84 AC A0A7T5QYJ2.1
#=GS A0A218MA20_9CAUD/2-81 AC A0A218MA20.1
#=GS I6XM06_9CAUD/3-83 AC I6XM06.1
#=GS E5DRZ5_9CAUD/2-82 AC E5DRZ5.1
#=GS A0A482GDR6_9CAUD/2-81 AC A0A482GDR6.1
#=GS A0A3T0IMX7_9CAUD/1-83 AC A0A3T0IMX7.1
#=GS A0A5B7LFA5_9CAUD/1-81 AC A0A5B7LFA5.1
#=GS A0A6B9WQE2_9CAUD/2-81 AC A0A6B9WQE2.1
#=GS A0A0A0YQI0_9CAUD/1-81 AC A0A0A0YQI0.1
#=GS E1A2L6_9CAUD/2-82 AC E1A2L6.1
#=GS A0A2Z5ZCZ7_9CAUD/2-81 AC A0A2Z5ZCZ7.1
#=GS A0A6B9SVJ7_9CAUD/2-82 AC A0A6B9SVJ7.1
#=GS A0A2H4YFD5_9CAUD/2-82 AC A0A2H4YFD5.1
#=GS A0A7U0G8X7_9CAUD/1-78 AC A0A7U0G8X7.1
#=GS A0A386K834_9CAUD/1-81 AC A0A386K834.1
#=GS K4I5W1_9CAUD/1-81 AC K4I5W1.1
#=GS A0A4Y5TT95_9CAUD/1-81 AC A0A4Y5TT95.1
#=GS G0YKD2_9CAUD/2-80 AC G0YKD2.2
#=GS A0A7D7IKJ0_9CAUD/1-81 AC A0A7D7IKJ0.1
#=GS A0A219YAY3_9CAUD/2-83 AC A0A219YAY3.1
#=GS A0A811ANE5_9CAUD/2-81 AC A0A811ANE5.1
#=GS A0A5B9NFE4_9CAUD/9-89 AC A0A5B9NFE4.1
#=GS A0A5B9NLD3_9CAUD/1-81 AC A0A5B9NLD3.1
#=GS A0A0A0Q3M9_9CAUD/1-81 AC A0A0A0Q3M9.1
#=GS A8R9N6_9CAUD/1-81 AC A8R9N6.1
#=GS A0A2I6PF68_9CAUD/1-83 AC A0A2I6PF68.1
#=GS A0A097J1C7_BPR03/2-81 AC A0A097J1C7.1
#=GS A0A2S1PGL4_9CAUD/1-83 AC A0A2S1PGL4.1
#=GS J7KLV4_9CAUD/3-84 AC J7KLV4.1
A0A7S5SK01_9CAUD/2-82 ..s-KKVELLKDIVATISVMVKLGV.EgE..............V....LDTQ.TNLIAFLSEAGFTTTSGKPLTQMNFRYMF..GSCTHDEIREILSEFSA----------qhayd...
A0A240F2V9_9CAUD/2-83 nys----ENIKDIIATASLLIKFGC.E.D..............I....LNKQ.ETFVSFLNELGFRSPTGEEFTRAGFRQMM..KRLPIEQREELIEMFNQGH--------rdvnhq..
K0G7R3_9CAUD/2-81 ...NKDIEIVREIITIASILIKFSR.E.D..............I....VEDR.ASFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
E5E4L6_9CAUD/2-80 .lf----NTLAEIIAVASILIKFGF.D.D..............I....LENH.NLFIAYLNELEI-TIQGKKVTSANLYMLT..QEITTSQKKQLIEEFNMGHEP------iyr.....
I7AUC1_9CAUD/2-81 ...NKNIDTVREIITVASILIKFSR.E.D..............I....VENR.ANFIAFLNEIGV-THEGRKLNQNSFRKIV..SELTQEDKKTLIDEFNEGF----EGVY........
Q56ED8_9CAUD/2-83 nys----ENIKDIIATASLLIKFGC.E.D..............I....LNKQ.ETFVSFLNELGFRSPTGEEFTRAGFRQMM..KRLPIEQREELIEMFNQGH--------rdvnhq..
A0A6G6XH77_9CAUD/2-81 ...NKDIEIVREIITIASILIKFSR.E.D..............I....VEDR.ASFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
A0A7G9VYE8_9CAUD/2-82 .vy----ETLAEIIAVVSILIKFGH.D.D..............I....LEDK.NLFIAFLNELGI-TINGKKVTAGNLFNLT..QDITTRQKEQLIAEFNIGHAP------iykkl...
A0A7S9XC63_9CAUD/1-84 .ms---VELVREIFTVASLLIKFDS.E.D..............IlerrVEGK.RLFIEVLNELGIRNTNNKPLTESSFKKLI..QGLSKEEKESLIEEFNQGF--------qaiy....
A0A1Z1LYR6_9CAUD/1-81 ..m-SKIEIVREIVTVASILIKTSC.E.D..............I....LEKR.ENFIAFLNELGLRNEHGRELNLANFKKMI..DGLNDDERSSLVEEFNEGF----EDI-y.......
A0A223LF16_9CAUD/3-83 .yn----ETIKEIISIASVLIKFGC.E.D..............I....LNNQ.ELFVSFLNELGLKSPSGEEFTRAGFRQMM..KRLPADQREELVEMFNQGH--------rdinhq..
E5DHZ2_9CAUD/1-81 ..m-SKLEIVREIVTVASVLIKFGS.E.H..............I....LEKR.EHFIAFLNEIGIKNDLGRPLNQSNFRKMI..EEMTAEEKQQLVEEFNEGF----ESVY........
A0A2U7NLX5_9CAUD/20-101 .sf--NKESIMDIIATMSILIKFDA.D.D..............I....LDNI.NLFAEYLNELGFRTVEGFELNKYRLKRMFfnSGLSREDMTGLFDE-------------hferlnrk
A0A3P4AA03_9CAUD/2-81 ...NKDIEIVREIITIASILIKFSR.E.D..............I....VEDR.ASFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
A0A0B6VPM1_9CAUD/1-80 mtk---FEIISEIVTIASILIKTDC.D.D..............I....MWKR.DHFIAFLNEAGIRNESGKELNGVSFNKLF..-DLTEDEREKLIEQFNEGY--------edvh....
Q6WHK8_BPKVM/10-94 ...KSTPELALDIAAYASLLVKMGY.D.E..............C....VTNQ.KLFVEMCNEAGFRTTTGKEFTQMSFRQMF..ARLPQGTKREVRESFSWGNVPQGESIL........
A0A0G2SSC2_9CAUD/1-82 .mn--KLETLSEIFAVISILIKFES.E.D..............I....IEDE.NLFIAFINELGI-RNNGKLFNKSNLKSLV..KSLSDEEKTKLIEEFNTGH--------kstysl..
A0A7T5UD27_9CAUD/1-81 .ms--KFEIVREIITIASILIKFGR.D.D..............I....VEKR.DHFIAFINETHANDKEWKRLNQSSFRKMV..SDLTDDEKTKLVEEFNEGY----EGIY........
A0A6B9J5B4_9CAUD/2-82 .vy----ETLAEIIAVVSILIKFGH.D.D..............I....LEDK.NLFIAFLNELGI-TINGKKVTAAGLFNLT..QDITTRQKEQLIAEFNIGHAP------iykkl...
A0A023W6W7_9CAUD/1-95 ..m-NNVEFVREVMTVVSIVIKFGC.E.EpsqeamridpsyrgV....IAKH.RHFVPFLVELGMKHPSGRELTVGNFRQVM..TELTIDEKEELIEEFNQGF--------rhiy....
A0A0A7HC73_9CAUD/1-81 mtk---FEIVSEIVTVTSILIKTDR.E.D..............I....TMKR.DVFIAFLNELGLRNENGNELNNVSFNKLF..KSLSEDEIEQIIEQFNEGF--------edih....
A0A1D3RL15_9CAUD/1-81 ..m-SKIEIVREIVTVASVLIKFGS.E.H..............I....LEKR.EHFIAFLNEIGIKNDLGRPLNQSNFRKMI..EEMTAEEKQQLVEEFNEGF----ESVY........
A0A240F458_9CAUD/2-83 nys----ENIKDIIATASLLIKFGC.E.D..............I....LNKQ.ETFVSFLNELGFRSPTGEEFTRAGFRQMM..KRLPIEQREELIEMFNQGH--------rdvnhq..
A0A097J6U1_BPR32/2-81 ...NKNIDTVREIITVASILIKFSR.E.D..............I....VENR.ANFIAFLNEIGV-THEGRKLNQNSFRKIV..SELTQEDKKTLIDEFNEGF----EGVY........
J7I4K9_9CAUD/1-83 msy---NETIKEIISIASVLIKFGC.E.D..............I....LNNQ.ELFVSFLNELGLKSPSGEEFTRAGFRQMM..KRLPADQREELVEMFNQGH--------rdvnhq..
A0A5B9NCJ7_9CAUD/1-81 mtk---FEIVQEIVTVASILTKFNA.E.H..............I....MEKR.DEFIAFLNEIGIKNEQGRQLNQSNFRKMV..SELTDEEKRILVEEYNEGF----ESIY........
D9I6I4_9CAUD/1-80 .my----EVLAEVIAVASILIKFGY.D.E..............I....LENK.VLFVAFLNELKIKSHTGAPITVHTLTTMS..ENITTREQRQLIDEFNIGHEP------lyr.....
R9TEX8_9CAUD/10-94 ...KSTPELALDIAAYASLLVKLGY.E.D..............C....VTNQ.KLFVEMCNEAGFRTTTGKEFTQMSFRQMF..ARLPQGTKREVRESFSWGNIPTSESIL........
A0A0K1LP27_9CAUD/1-81 .mt--NFEIVREVVTIASILIKFGR.D.D..............I....VEKR.DHFIAFINETHVDDKDWRRLNQGSFRKLI..YELTVDEKKLLVEEFNEGY----EDI-y.......
A0A060AMS7_9CAUD/4-84 .te--STELCRDIVATASILIKFEM.C.H..............I....MDSQ.SSFVEFLNAAGFRTVRGKEFSKMSFRKMW..ERLSPSEIKDILSEFDSR---------nfdil...
A0A6B9Y0V3_9CAUD/1-81 mtk---FEIVSEIATIVSILIKTDC.E.D..............V....MWKK.DNFIAFLNELGIRTETGRELTNLSFNKLF..RELSEDERELLIEQFNEGY--------edih....
A0A0U4IH54_9CAUD/8-90 ...NTKIDLIMDMIAALSILIKFDMaD.E..............I....LENQ.HNVVAFLDELGFKTLSGQKLTVMNFRYII..SSLRPNDKNKVINEFKMAF--------espki...
A0A7G5AYG1_9CAUD/3-83 .it--KVELMKDIVATASILAKYGC.D.D..............I....LDTQ.SGFVDFLNELGFTTVRGKPLTIFNFRVMV..NSLTPYQKKEIVKEFDAGRI-------dhl.....
A0A088FW16_9CAUD/2-81 ...NKDIEIVREIITIASILIKFSR.E.D..............I....VEDR.ANFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
A0A6J3ZYV6_BPT2/2-81 ...NKNIDTVREIITVASILIKFSR.E.D..............I....VENR.ANFIAFLNEIGV-THEGRKLNQNSFRKIV..SELTQEDKKTLIDEFNEGF----EGVY........
A0A219YC78_9CAUD/2-82 .sn--KIEVLKDIVATASILIKFGR.D.D..............I....LDTQ.RGFIDFLSTAGFTTPSGKPLTIQNFRVMV..KSLKPSQIKEIFEEFDAGRI-------ydm.....
A0A5P8PHQ3_9CAUD/1-95 ..m-NNVEFVREVMAVVSIVIKFGC.E.EpsqeamridpsyrgV....IAKH.RHFVPFLVELGMKHPSGRELTVGNFRQVM..TELTNDEKEELIEEFNQGF--------rhiy....
A0A873WSL1_9CAUD/1-78 .ml----EDIRDIFAVVSILIKFER.E.D..............I....FQNP.NLFIEFLNELGF-RSNGRALTRQNFTKMI..QSLSEADKTEMIEEFNEGH--------kaiy....
A0A868BRA5_BPFBB/1-82 ..m-SKLEIVREIITVSSILIKFGS.E.D..............I....LQGKtENYVAFLNELGIRNESGRQLNVASFKKLM..RELSQDEREVLIEEFNEGF--------adiy....
A0A411BIC7_9CAUD/3-84 ..n-TKVEILKDIVATASILVKYDC.E.D..............I....LDTQ.TGFIDFLNELGFTTIRGKPLTQHNFKIML..KSMTDYQIKEALKEFDAGKI-------sdmi....
A0A3Q9R7G8_9CAUD/2-82 .vf----ETLAEIAAVVSILIKFGH.D.D..............I....IEDK.NLFIAFLNELGI-TINGKKVTAGNLFNLT..QDITNRQKEQLIAEFNIGHAP------iykkl...
A0A410T4S4_9CAUD/1-81 .mt--KIEIVSEIATIVSILIKTDC.E.D..............I....MQRR.DEFIAFLNELGIRNEHGKELNGLSYNKLF..KSLTEDERETLIEQFNEGY--------edih....
Q7Y4Q5_BPR69/2-81 ...NKDIEIVREIITIASILIKFSR.E.D..............I....VEDR.ANFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
A0A0B5A2R8_9CAUD/1-81 mtk---LEIIREIVTIVSILIKTDC.D.D..............I....LTSR.DGFIAFLNEAGIRNEFGRTLNGANFKKLA..DGLSVEEKEMLIEEFNTGY----EDI-y.......
M1EAI1_BPS16/1-81 mtk---FEVAREVVTIASLLIKFGR.D.D..............I....VDKR.DNFIAFINETMSADKNWKQLNQSSFRKII..SDLTAEEKGMLVEEFNEGF----EDI-y.......
E5EQ30_9CAUD/1-80 .ma---FETLCEIVAVASILIKFGH.D.D..............I....LEHR.PLFIAFLNELGI-TVNARKVTSASLFELT..QDITNRQREQLISDFLVGHE-------piyr....
A0A2S1GM14_9CAUD/1-82 ..m-SKLETVREIITVASILIKFGA.E.D..............I....LQGKsDEFVAFLNEIGI-RNEGRELNVASFKKMI..KELSLEDKEILVEEFNEGY--------advyr...
A0A6B9STF7_9CAUD/10-94 ...KSTPELALDIAAYASLLVKMGY.D.E..............C....VTNQ.KLFVEMCNEAGFRTTTGKEFTQMSFRQMF..ARLPQGTKREVRESFSWGNVPQGESIL........
A0A346FJY1_BPT6/2-81 ...NKNIDTVREIITVASILIKFSR.E.D..............I....VENR.ANFIAFLNEIGV-THEGRKLNQNSFRKIV..SELTQEDKKTLIDEFNEGF----EGVY........
A0A192YBU6_9CAUD/1-77 ..m----NLAEEIVTIVSILIKFEC.D.D..............I....LDNQ.ELFVEFLNELGL-RNNGRSLSKVNMATLF..ERMTAAERKRIIENFNIGH--------qsly....
A0A411BAG5_9CAUD/2-82 ..n-AKLELIKDIIATVSLIIKLEV.DgE..............I....LDSQ.QNLIDFLNEAGFRTVRGLEFTKMSFRQMI..GRMTDKERNEVLKEFSA----------qehye...
A0A2Z4QAR6_9CAUD/1-81 mtk---FEIVQEIVTVASILTKFNA.E.H..............I....MEKR.DEFIAFLNEIGIKNEQGRQLNQSNFRKMV..SELTDEEKRILVEEYNEGF----ESIY........
E5EZ20_BPAC4/2-80 .yn-----ILADIIATASILIKFGH.D.D..............I....LENQ.RTFVAFLNELGFKTVEGRPITLTNLFNMT..QDITTREKDKLIEEFNIGHEP------iyr.....
ASIA_BPT4/2-81 ...NKNIDTVREIITVASILIKFSR.E.D..............I....VENR.ANFIAFLNEIGV-THEGRKLNQNSFRKIV..SELTQEDKKTLIDEFNEGF----EGVY........
A0A0B6VLD1_9CAUD/1-80 mtk---FEIISEIVTIASILIKTDC.D.D..............I....MWKR.DHFIAFLNEAGIRNESGKELNGVSFNKLF..-DLTEDEREKLIEQFNEGY--------edvh....
D4ZA57_BPAR1/2-81 ...NKNIDTVREIITVASILIKFSR.E.D..............I....VENR.ANFIAFLNEIGV-THEGRKLNQNSFRKIV..SELTQEDKKTLIDEFNEGF----EGVY........
A0A067ZK43_9CAUD/2-81 ...NKDIEIVREIITVASILIKFSR.E.D..............I....VEDR.ANFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
A0A7T8F0N6_9CAUD/2-82 .vf----ETLAEIAAVVSILIKFGH.D.D..............I....IEDK.NLFIAFLNELGI-TINGKKVTAGNLFNLT..QDITNRQKEQLIAEFNIGHAP------iykkl...
A0A3T0IMA2_9CAUD/1-81 .mt--KIEIVSEIATIVSILIKTDC.E.D..............I....MQRR.DEFIAFLNELGIRNEHGKELNGLSYNKLF..KSLTEDERDTLIEQFNEGY--------edih....
A0A7T6ZLP2_9CAUD/1-78 .ml----NTVREIINVASILIKFDC.E.D..............I....LENK.PLFIEFINELGL-RNNGKLFNKSNFAKLM..SSLSDEEKATVIEEFNVGH--------ksvy....
I7J414_BPPR1/1-81 mte---LEIIREIVTIVSILIKTDC.D.D..............I....LTSR.DGFIAFLNEAGIRNEFGRTLNGANFKKLA..DGLSVEEKEMLIEEFNTGY----EDI-y.......
E5FJ32_9CAUD/1-81 mtk---FEIVSEIVTVTSILIKTDR.E.D..............I....TMKR.DVFIAFLNELGLRNENGNELNNVSFNKLF..KSLSEDEIEQIIEQFNEGF--------edih....
E5DQQ2_9CAUD/2-82 ..n-AKLELIKDIIATVSLIIKLEV.DgE..............I....LDSQ.QNLIDFLNEAGFRTVRGLEFTKMSFRQMI..GRMTDKERNEVLKEFSA----------qehye...
A0A1W6JU55_9CAUD/2-81 ...NKDIEIVREIITIASILIKFSR.E.D..............I....VEDR.ANFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
A0A6H0X733_9CAUD/10-94 ...KSTPELALDIAAYASLLVKMGY.D.E..............C....VTNQ.KLFVEMCNEAGFRTTTGKEFTQMSFRQMF..ARLPQGTKREVRESFSWGNVPQGESIL........
A0A0A7HD11_9CAUD/1-81 mtk---FEIVSEIVTVTSILIKTDR.E.D..............I....TMKR.DVFIAFLNELGLRNENGNELNNVSFNKLF..KSLSEDEIEQIIEQFNEGF--------edih....
A0A2H4YGT9_9CAUD/1-81 .mt--NFEVVREVITIASILIKFGR.D.D..............I....VEKR.DHFIAFINETHVDDKDWRRLNQGSFRKLI..SELTADEKKMLIEEFNEGY----EDI-y.......
A0A345AV77_9CAUD/2-82 .vy----ETLAEIIAVVSILIKFGH.D.D..............I....LEDK.NLFIAFLNELGI-TINSKKVTAGNLFNLT..QDITTRQKEKLINEFNVGHAP------iykkl...
A0A7T5QYJ2_9CAUD/3-84 ..n-TKVEILKDIVATASILVKYDC.E.D..............I....LDTQ.TGFIDFLNELGFTTIRGKPLTQHNFKIML..KSMTDYQIKEALKEFDAGKI-------sdmi....
A0A218MA20_9CAUD/2-81 ...NKDIEIVREIITIASILIKFSR.E.D..............I....VEDR.ASFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
I6XM06_9CAUD/3-83 .it--KVELMKDIVATASILAKYGC.D.D..............I....LDTQ.SGFVDFLNELGFTTVRGKPLTIFNFRVMV..SSLTQYQKKEIIKEFDAGRI-------dhl.....
E5DRZ5_9CAUD/2-82 .sn--KIEVLKDIVATASILIKFGR.D.D..............I....LDTQ.RGFIDFLSTAGFTTPSGKPLTIQNFRVMV..KSLKPSQIKEIFEEFDAGRI-------ydm.....
A0A482GDR6_9CAUD/2-81 ...NKDIEIVREIITIASILIKFSR.E.D..............I....VEDR.ASFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
A0A3T0IMX7_9CAUD/1-83 .mn--KLETLSEIFAVISILIKFES.E.D..............I....IEDE.NLFIAFINELGI-RNNGKLFNRSNLKSLI..KSLTEDEKKQLIEEFNMGH--------kstysii.
A0A5B7LFA5_9CAUD/1-81 mtk---FEIVQEIVTVASILTKFNA.E.H..............I....MEKR.DEFIAFLNEIGIKNEQGRQLNQSNFRKMV..SELTDEEKRILVEEYNEGF----ESIY........
A0A6B9WQE2_9CAUD/2-81 ...NKDIEIVREIITIASILIKFSR.E.D..............I....VEDR.ASFIGFLNEIGI-KKDGRQLNQNSFRKLI..TNLTAEEKKTLISEFNEGF----ENIY........
A0A0A0YQI0_9CAUD/1-81 .mt--NFEIVREVVTIASILIKFGR.D.D..............I....VEKR.DHFIAFINETHVDDKDWRRLNQGSFRKLI..SELTVDEKKLLVEEFNEGY----EDI-y.......
E1A2L6_9CAUD/2-82 ..n-AKLELVKDIIATVSLLIKLEV.EgE..............I....LDTQ.QNLIDFLNEAGFRTVRGLEFTKMSFRQMV..GRLTDEERAEVLTEFSA----------qehye...
A0A2Z5ZCZ7_9CAUD/2-81 .lk---IEIVREIITVASILIKTSC.E.D..............I....LEKR.ETFIAFLNELGLRNEHGRELNLANFKKMI..DGLTDEERLSLVEEFNEGF----EDI-y.......
A0A6B9SVJ7_9CAUD/2-82 .vf----ETLAEIAAVVSILIKFGH.D.D..............I....IEDK.NLFIAFLNELGI-TINGKKVTAGNLFNLT..QDITNRQKEQLIAEFNIGHAP------iykkl...
A0A2H4YFD5_9CAUD/2-82 ..n-AKLELIKDIVATVSLIIKLEV.DgE..............I....LDTQ.QNLIDFLNEAGFRTVRGLEFTKMSFRQMI..GRLTPEERMEVLSEFSA----------qehye...
A0A7U0G8X7_9CAUD/1-78 .ml----NTVREIINVASILIKFDC.E.D..............I....LENK.PLFIEFINELGL-RNNGKLFNKSNFAKLM..SSLSDEEKATVIEEFNVGH--------ksvy....
A0A386K834_9CAUD/1-81 mtk---FEIVQEIVTVASILTKFNA.E.H..............I....MEKR.DEFIAFLNEIGIKNEQGRQLNQSNFRKMV..SELTDEEKRILVEEYNEGF----ESIY........
K4I5W1_9CAUD/1-81 mtk---FEVAREVVTIASLLIKFGR.D.D..............I....VDKR.DNFIAFINETMSADKNWKQLNQSSFRKII..SDLTAEEKGMLVEEFNEGF----EDI-y.......
A0A4Y5TT95_9CAUD/1-81 .ms--KFEIVSEIITMASLLIKFQR.E.D..............I....LENR.EGFIAFLNECGIRNEFGRELNSANFRKMI..AELSDEEKKQLIQEFNVGH----ESVY........
G0YKD2_9CAUD/2-80 .lf----ETLQEIIAVASILIKFGH.D.D..............I....LENK.ALFIAFLNELGI-TIGNKKVTATSLWNLT..QDITNRQKEALIEEFLSGHEP------iyr.....
A0A7D7IKJ0_9CAUD/1-81 mtk---FEIVSEIVTVTSILIKTDR.E.D..............I....TMKR.DVFIAFLNELGLRNENGNELNNVSFNKLF..KSLSEDEIEQIIEQFNEGF--------edih....
A0A219YAY3_9CAUD/2-83 nys----ENIKDIIATASLLIKFGC.E.D..............I....LNKQ.ETFVSFLNELGFRSPTGEEFTRAGFRQMM..KRLPIEQREELIEMFNQGH--------rdvnhq..
A0A811ANE5_9CAUD/2-81 ...NKNIDTVREIITVASILIKFSR.E.D..............I....VENR.ANFIAFLNEIGV-MHEGRKLNQNSFRKIV..SELTQEDKKTLIDEFNEGF----EGVY........
A0A5B9NFE4_9CAUD/9-89 .ms--KFEIVSEIITMASLLIKFQR.E.D..............I....LENR.EGFIAFLNECGIRNEFGRELNSANFRKMV..AELSDDEKKQLIQEFNVGH----ESVY........
A0A5B9NLD3_9CAUD/1-81 mtk---FEIVQEIVTVASILTKFNA.E.H..............I....MEKR.DEFIAFLNEIGIKNEQGRQLNQSNFRKMV..SELTDEEKRILVEEYNEGF----ESIY........
A0A0A0Q3M9_9CAUD/1-81 .mt--NFEIVSEIATIVSILIKTDC.E.D..............V....MGKR.DEFIAFLNELGIRNEASKELNNVSFNKLF..KDLSENEKLLLIEQFNEGY--------edih....
A8R9N6_9CAUD/1-81 mtk---FEIVSEIVTITSILIKTDR.E.D..............I....TMKR.DVFIAFLNELGLRNENGNELNNVSFNKLF..KSLSEDEIEQIIEQFNEGF--------edih....
A0A2I6PF68_9CAUD/1-83 .mn--KLETLSEIFAVISILIKFES.E.D..............I....IEDE.NLFIAFINELGI-RNNGKLFNRSNLKSLI..KSLTEDEKKQLIEEFNMGH--------kstysii.
A0A097J1C7_BPR03/2-81 ...NKNIDTVREIITVASILIKFSR.E.D..............I....VENR.ANFIAFLNEIGV-THEGRKLNQNSFRKIV..SELTQEDKKTLIDEFNEGF----EGVY........
A0A2S1PGL4_9CAUD/1-83 msy---NETIKEIISIASVLIKFGC.E.D..............I....LNNQ.ELFVSFLNELGLKSPSGEEFTRAGFRQMM..KRLPADQREELVEMFNQGH--------rdvnhq..
J7KLV4_9CAUD/3-84 .yn----ETIKEIISIASVLIKFGC.E.D..............I....LNNQ.ELFVSFLNELGLKSPSGEEFTRAGFRQMM..KRLPADQREELVEMFNQGH--------rdvnhqm.
#=GC seq_cons ......hEllcEIlslASILIKFup.E.D..............I....l-s+.stFIuFLNElGlpspsG+pLspssF+phh..pcLTs--KcpLI-EFNpGa................
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