#=GF ID   AvrPphF-ORF-2
#=GF AC   PF09143.14
#=GF DE   AvrPphF-ORF-2
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1s21
#=GF GA   25.00 25.00;
#=GF TC   25.60 29.40;
#=GF NC   24.60 24.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0084
#=GF RN   [1]
#=GF RM   15341731
#=GF RT   Crystal structures of the type III effector protein AvrPphF and
#=GF RT   its chaperone reveal residues required for plant pathogenesis. 
#=GF RA   Singer AU, Desveaux D, Betts L, Chang JH, Nimchuk Z, Grant SR,
#=GF RA   Dangl JL, Sondek J; 
#=GF RL   Structure. 2004;12:1669-1681.
#=GF DR   INTERPRO; IPR015226;
#=GF DR   SCOP; 1s21; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family of plant pathogenic proteins adopt an
#=GF CC   elongated structure somewhat reminiscent of a mushroom that can
#=GF CC   be divided into 'stalk' and 'head' subdomains. The stalk
#=GF CC   subdomain is composed of the N-terminal helix (alpha1) and beta
#=GF CC   strands beta3-beta4. An antiparallel beta sheet (beta5,
#=GF CC   beta7-beta8) forms the base of the head subdomain that interacts
#=GF CC   with the stalk. A pair of twisted antiparallel beta sheets
#=GF CC   (beta1 and beta6; beta2 and beta9/9') supported by alpha2 form
#=GF CC   the dome of the head. The head subdomain possesses weak
#=GF CC   structural similarity with the catalytic portion of a number of
#=GF CC   ADP-ribosyltransferase toxins [1].
#=GF SQ   8
#=GS A0A421DL53_9GAMM/29-199  AC A0A421DL53.1
#=GS A1TRM9_ACIAC/83-173      AC A1TRM9.1
#=GS Q88A90_PSESM/29-204      AC Q88A90.1
#=GS Q8XB62_ECO57/57-213      AC Q8XB62.1
#=GS A0A1G9L1L1_9PSED/31-199  AC A0A1G9L1L1.1
#=GS Q8XRK9_RALSO/153-338     AC Q8XRK9.2
#=GS A0A081NHE9_9GAMM/54-211  AC A0A081NHE9.1
#=GS A0A014NBN5_9GAMM/45-218  AC A0A014NBN5.1
A0A421DL53_9GAMM/29-199             ..........tntr----GGQTINSVNDLPPAEKEAFLNVHDPVRAMNLNENTLLYRSTDKRFI....SRGHLKGNPNS.IARIFNYDRLRPNP.YLQL..VT.HR--NAP.........PYFPVEMRA...SELKDPSLNVMVG...LQAREAILQYAK.-RDNVSVEMRLGDFMRQGGKVYSDTSS-AISSNYATALVVTLPKGSSVPVTII..............
A1TRM9_ACIAC/83-173                 .......yvlkngr-------VFPSVNTLPPAERAAFLKKHDPCSQLKLNDDSVFFRVTERQWV....QDGTLSGHPQS.GARIRNHFAIAENP.YM--..--.-------.........---------...-------------...------------.-----------------------------------------------------pgsfkpaemdamhl
Q88A90_PSESM/29-204                 ..............STHVGGDTLTSIHQLSHSQREQFLNMHDPMRVMGLDHDTELFRTTDSRYI....KNDKLAGNPQS.MASILMHEELRPNR.FASH..TG.AQPHEAR.........AYVPKRIKA...TDLGVPSLNVMTG...SLARDGIRAYDHmSDNQVSVKMRLGDFLERGGKVYADASSVADDGETSQALIVTLPKGQKVPVERV..............
Q8XB62_ECO57/57-213                 ..qeknitervlsi--------------------------------FKIKRDFVAVRIQNNQFTd..lKNKKIQGHQNT.VASVMDWYNPQKNA.LGIT..MG.TPRKSAD.........IAKEEHRNA...LNFMIMEKNTFHEkilNSNDNLQKSYSK.TEDSSWVAASVGSLLDKGAKVYPDTSCSLRL---GEPFIFTLPESVRVDVDI-y.............
A0A1G9L1L1_9PSED/31-199             ..........pvse----GGNRLTSVDQLNSRERQRFLKSHDPMEIYKLKRDTPLYRTMPAEYL....VDGRVSGNPNS.CALIRNHERLRPNP.Y---..-G.GQPGTAS.........AYWTVQHRA...YELG-PSLNVMAG...NDAQASTAPYHQ.-EGNVTVEMRLGDFLERGGKAYVDESAGKGDGIDAIPLIVTLPEGESVPARRI..............
Q8XRK9_RALSO/153-338                .........ssppy---------IPVDALPPPLSKAFLEAFDPIRSLGLTDQSVFYRALASRYLladgHQMKLAGNPRS.GAYVRHHHRLLPSSgLASRetFE.SLPATARermlndpmqQYEWVRMRA...RDLPEPSLNVMFG...VHAEAGARSYAK.TSDHVVVSMTFGDLRKAGGQVFLDTRA-SAGSDHTKALIVTLPKGRTVPVKII..............
A0A081NHE9_9GAMM/54-211             sppsaqtdsitklv-----------------------------MDKYELSPDTRVFRMCDKKFLd..lNNMRAHGNPTPeSTQVRDFYNMVEDP.VTKG.yIEhCKRNNIS.........APEPRLISGktfADKLAPCLNVS--...--VEPAVDYYVE.--GMVLFSFRLGDALDIGARIYPDETSVA---QLTTPLIITIPTDKTVPIQ--l.............
A0A014NBN5_9GAMM/45-218             ..........ssps-----GERLTSVYQLSSKERKKFLNNHDPMKRFGLSSSTPVYRTTHKSYV...dEDGMMAGNPHS.GALIEMHEELAPNP.FARS..NG.FRPDEAR.........AYVPRKESA...HNLGVPSLNVMVG...AGALGSVKRYAQ.-DDHVTTKMKLGDFLNRGGKVYTDYSAVAGNGDTTNALLVTLPEGEKVPVKIV..............
#=GC seq_cons                       ..........sssh.......hhsSVppLsstp+ptFLp.HDPhcthpLscDTslaRsscpcal....pss+luGNPpS.sApIcsHccLtPNP.aspt..hs.sp.tsAp.........sYhshchpA...t-Lh.PSLNVMhG...stAcsuhctYsc..cspVsVpM+LGDhLcpGGKVYsDpSusutsuphspsLIVTLPcGppVPVchl..............
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